MXPA04004532A - Medicamento para el tratamiento de enfermedades tumorales y virales de la piel. - Google Patents

Medicamento para el tratamiento de enfermedades tumorales y virales de la piel.

Info

Publication number
MXPA04004532A
MXPA04004532A MXPA04004532A MXPA04004532A MXPA04004532A MX PA04004532 A MXPA04004532 A MX PA04004532A MX PA04004532 A MXPA04004532 A MX PA04004532A MX PA04004532 A MXPA04004532 A MX PA04004532A MX PA04004532 A MXPA04004532 A MX PA04004532A
Authority
MX
Mexico
Prior art keywords
group
alkyl
alkylene
alkinyl
independently
Prior art date
Application number
MXPA04004532A
Other languages
English (en)
Inventor
Moebius Ulrich
Original Assignee
Medigene Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26010614&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA04004532(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10156794A external-priority patent/DE10156794B4/de
Application filed by Medigene Ag filed Critical Medigene Ag
Publication of MXPA04004532A publication Critical patent/MXPA04004532A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La invencion se relaciona a un medicamento que contiene un compuesto de la formula(ver formula)en donde R1= independiente, es un grupo opcionalmente sustituido de alquilo de C11-C21, alquileno o alquinilo, lineal o ramificado, saturado, sencillo o multiplicadamente insaturado, preferiblemente un grupo de alquilo de C11-C15, alquileno o alquinilo, particularmente un grupo alquilo de C11-C13 , alquileno o alquinilo, mas preferiblemente un grupo alquilo C13, R2 = independiente, un grupo de alquilo de C1-8, alquileno o alquinilo, lineal o ramificado, preferiblemente un grupo alquilo de C1-C6, alquileno o alquinilo, mas preferiblemente un grupo alquilo, un grupo -(CH2-(CH2)m-O)n-H, con n = 1 a 10, preferiblemente n = 1 a 5, m = 1 a 5, preferiblemente m = 1 a 3, un grupo -(CH2-(CH-(OH))p-(CH2 -(R3)), donde R3 = independiente H u OH, p = 1 a 7, preferiblemente p = 1 a 4, un grupo pentosa o un grupo hexosa, como agente terapeuticamente activo, solo o en combinacion con uno o varios agentes farmaceuticos adicionales como una preparacion en combinacion para el tratamiento de enfermedades de la piel virales y/o enfermedades tumorales, en particular, provocadas por virus de papiloma humano (HPV) y/o virus herpes y una formulacion de medicamento topicamente activo y el uso de los mismos.
MXPA04004532A 2001-11-19 2002-11-18 Medicamento para el tratamiento de enfermedades tumorales y virales de la piel. MXPA04004532A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33170501P 2001-11-19 2001-11-19
DE10156794A DE10156794B4 (de) 2001-11-19 2001-11-19 Arzneimittel zur Behandlung von Warzen
PCT/EP2002/012919 WO2003043628A1 (de) 2001-11-19 2002-11-18 Arzneimittel zur behandlung von viralen haut- und tumorerkrankungen

Publications (1)

Publication Number Publication Date
MXPA04004532A true MXPA04004532A (es) 2004-08-11

Family

ID=26010614

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04004532A MXPA04004532A (es) 2001-11-19 2002-11-18 Medicamento para el tratamiento de enfermedades tumorales y virales de la piel.

Country Status (19)

Country Link
US (4) US7858662B2 (es)
EP (2) EP1448186B1 (es)
JP (1) JP4495459B2 (es)
KR (1) KR100956369B1 (es)
CN (1) CN1323660C (es)
AT (1) ATE417611T1 (es)
BR (1) BRPI0214256B8 (es)
CA (1) CA2466720C (es)
CY (1) CY1108882T1 (es)
DE (2) DE122009000073I1 (es)
DK (1) DK1448186T3 (es)
ES (1) ES2319626T3 (es)
HK (2) HK1073788A1 (es)
IL (2) IL161625A0 (es)
MX (1) MXPA04004532A (es)
PT (1) PT1448186E (es)
RU (1) RU2302861C3 (es)
WO (1) WO2003043628A1 (es)
ZA (1) ZA200403287B (es)

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US7858662B2 (en) 2010-12-28
BRPI0214256B1 (pt) 2016-06-28
IL161625A (en) 2010-05-31
DE122009000073I1 (de) 2010-03-25
HK1073788A1 (en) 2005-10-21
CN1323660C (zh) 2007-07-04
EP2055300A3 (de) 2010-05-12
CA2466720A1 (en) 2003-05-30
US20200054552A1 (en) 2020-02-20
ZA200403287B (en) 2005-07-27
BR0214256A (pt) 2004-09-21
KR20050044344A (ko) 2005-05-12
AU2002356673A1 (en) 2003-06-10
US20050032895A1 (en) 2005-02-10
US10434059B2 (en) 2019-10-08
RU2004118667A (ru) 2005-04-10
ES2319626T3 (es) 2009-05-11
DE50213137D1 (de) 2009-01-29
CA2466720C (en) 2010-02-09
US20110009481A1 (en) 2011-01-13
EP2055300A2 (de) 2009-05-06
CY1108882T1 (el) 2014-07-02
WO2003043628A1 (de) 2003-05-30
JP4495459B2 (ja) 2010-07-07
RU2302861C3 (ru) 2017-04-14
DK1448186T3 (da) 2009-04-14
KR100956369B1 (ko) 2010-05-10
BRPI0214256B8 (pt) 2021-05-25
US9770406B2 (en) 2017-09-26
IL161625A0 (en) 2004-09-27
PT1448186E (pt) 2009-03-24
ATE417611T1 (de) 2009-01-15
EP1448186A1 (de) 2004-08-25
US20180193254A1 (en) 2018-07-12
JP2005514358A (ja) 2005-05-19
HK1131048A1 (zh) 2010-03-12
CN1589141A (zh) 2005-03-02
EP1448186B1 (de) 2008-12-17
RU2302861C2 (ru) 2007-07-20

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