BR0214256A - Medicamento e uso do mesmo - Google Patents

Medicamento e uso do mesmo

Info

Publication number
BR0214256A
BR0214256A BR0214256-2A BR0214256A BR0214256A BR 0214256 A BR0214256 A BR 0214256A BR 0214256 A BR0214256 A BR 0214256A BR 0214256 A BR0214256 A BR 0214256A
Authority
BR
Brazil
Prior art keywords
patients
cure
alkenyl
alkyl
active agent
Prior art date
Application number
BR0214256-2A
Other languages
English (en)
Other versions
BRPI0214256B1 (pt
BRPI0214256B8 (pt
Inventor
Yunik Chang
Robert Lathrop
Erwin B Hm
Irene Gander-Meisterernst
Regina Greger
Johanna Holldack
Ulrich Moebius
Original Assignee
Medigene Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26010614&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0214256(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10156794A external-priority patent/DE10156794B4/de
Application filed by Medigene Ag filed Critical Medigene Ag
Publication of BR0214256A publication Critical patent/BR0214256A/pt
Publication of BRPI0214256B1 publication Critical patent/BRPI0214256B1/pt
Publication of BRPI0214256B8 publication Critical patent/BRPI0214256B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

"MEDICAMENTO E USO DO MESMO". A invenção refere-se a um medicamento contendo um composto de fórmula geral (I), onde R~ 1~ = independentemente, um grupo alquila C~ 11~-C~ 21~, alquileno ou alquinila reto ou ramificado, saturado, insaturado de modo único ou múltiplo, opcionalmente substituído, preferivelmente um grupo alquila C~ 11-C~ 15~, alquileno ou alquinila, particularmente um grupo alquila C~ 11~-C~ 13~, alquileno ou alquinila, mais preferivelmente um grupo alquila C~ 13~, R2 = independentemente, um grupo alquila C~ 1~-C~ 8~, alquileno ou alquinila reto ou ramificado, preferivelmente um grupo alquila C~ 1~-C~ 6~, alquileno ou alquinila, em particular um grupo alquila C~ 2~-C~ 4~, alquileno ou alquinila, mais preferivelmente um grupo alquila C~ 3~, um grupo -[CH~ 2~-(CH~ 2~)~ m~-O]~ n~H com n = 1 a 10, preferivelmente n = 1 a 5,m = 1 a 5, preferivelmente m = 1 a 3, um grupo -CH~ 2~-[CH-(OH)]~ p~ [CH~ 2~-(R~ 3~)]-, onde R~ 3~ = independentemente H ou OH, p = 1 a 7, preferivelmente p = 1 a 4, um grupo pentose ou um grupo hexose, como um agente terapeuticamente ativo, sozinho ou em combinação com um ou vários outros agentes farmacêuticos como uma preparação em combinação para o tratamento de doenças virais da pele e/ou doenças de tumor, em particular causada por papiloma vírus humano (HPV) e/ou vírus de herpes e uma formulação de medicamento de atuação tópica e o uso da mesma.
BRPI0214256A 2001-11-19 2002-11-18 medicamento BRPI0214256B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33170501P 2001-11-19 2001-11-19
DE10156794A DE10156794B4 (de) 2001-11-19 2001-11-19 Arzneimittel zur Behandlung von Warzen
PCT/EP2002/012919 WO2003043628A1 (de) 2001-11-19 2002-11-18 Arzneimittel zur behandlung von viralen haut- und tumorerkrankungen

Publications (3)

Publication Number Publication Date
BR0214256A true BR0214256A (pt) 2004-09-21
BRPI0214256B1 BRPI0214256B1 (pt) 2016-06-28
BRPI0214256B8 BRPI0214256B8 (pt) 2021-05-25

Family

ID=26010614

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0214256A BRPI0214256B8 (pt) 2001-11-19 2002-11-18 medicamento

Country Status (19)

Country Link
US (4) US7858662B2 (pt)
EP (2) EP1448186B1 (pt)
JP (1) JP4495459B2 (pt)
KR (1) KR100956369B1 (pt)
CN (1) CN1323660C (pt)
AT (1) ATE417611T1 (pt)
BR (1) BRPI0214256B8 (pt)
CA (1) CA2466720C (pt)
CY (1) CY1108882T1 (pt)
DE (2) DE122009000073I1 (pt)
DK (1) DK1448186T3 (pt)
ES (1) ES2319626T3 (pt)
HK (2) HK1073788A1 (pt)
IL (2) IL161625A0 (pt)
MX (1) MXPA04004532A (pt)
PT (1) PT1448186E (pt)
RU (1) RU2302861C3 (pt)
WO (1) WO2003043628A1 (pt)
ZA (1) ZA200403287B (pt)

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DE122009000073I1 (de) 2010-03-25
US9770406B2 (en) 2017-09-26
US20200054552A1 (en) 2020-02-20
HK1131048A1 (zh) 2010-03-12
EP2055300A2 (de) 2009-05-06
PT1448186E (pt) 2009-03-24
EP2055300B1 (de) 2016-01-27
CA2466720C (en) 2010-02-09
CY1108882T1 (el) 2014-07-02
ZA200403287B (en) 2005-07-27
MXPA04004532A (es) 2004-08-11
DE50213137D1 (de) 2009-01-29
KR20050044344A (ko) 2005-05-12
BRPI0214256B1 (pt) 2016-06-28
EP1448186A1 (de) 2004-08-25
RU2302861C3 (ru) 2017-04-14
US20050032895A1 (en) 2005-02-10
BRPI0214256B8 (pt) 2021-05-25
US20110009481A1 (en) 2011-01-13
EP1448186B1 (de) 2008-12-17
IL161625A (en) 2010-05-31
US7858662B2 (en) 2010-12-28
US20180193254A1 (en) 2018-07-12
JP4495459B2 (ja) 2010-07-07
IL161625A0 (en) 2004-09-27
US10434059B2 (en) 2019-10-08
JP2005514358A (ja) 2005-05-19
HK1073788A1 (en) 2005-10-21
AU2002356673A1 (en) 2003-06-10
CN1323660C (zh) 2007-07-04
ATE417611T1 (de) 2009-01-15
RU2302861C2 (ru) 2007-07-20
CN1589141A (zh) 2005-03-02
WO2003043628A1 (de) 2003-05-30
EP2055300A3 (de) 2010-05-12
ES2319626T3 (es) 2009-05-11
CA2466720A1 (en) 2003-05-30
DK1448186T3 (da) 2009-04-14
RU2004118667A (ru) 2005-04-10

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