UY23707A1 - Procedimiento para la preparacion de derivados del acido nonatetraenoico - Google Patents
Procedimiento para la preparacion de derivados del acido nonatetraenoicoInfo
- Publication number
- UY23707A1 UY23707A1 UY23707A UY23707A UY23707A1 UY 23707 A1 UY23707 A1 UY 23707A1 UY 23707 A UY23707 A UY 23707A UY 23707 A UY23707 A UY 23707A UY 23707 A1 UY23707 A1 UY 23707A1
- Authority
- UY
- Uruguay
- Prior art keywords
- procedure
- preparation
- acid derivatives
- nonatetraenoic acid
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Processing Of Meat And Fish (AREA)
- Optical Communication System (AREA)
- Compounds Of Unknown Constitution (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la preparación del compuesto ácido (all-E)-3,7-dimetil-9-[3,5-dimetil-2-(noniloxi)-fenil]-2,4,6,8-nonatetranoico con fórmula (I) representada en la figura 1, y sus sales farmacéuticamente aceptables y ésteres hidrolizables farmacéuticamente aceptables, que comprende hacer reaccionar un compuesto de fórmula (II) representada en la figura 2, donde Ph es fenilo y X- es un anión, bajo las condiciones de una reacción Witting con un compuesto de fórmula (III) representada en la figura 3; y si se desea, hidrolizar el grupo éster alquílico para obtener el ácido carboxílico de fórmula (I). Se incluye también un procedimiento conforme a lo descrito para la preparación de una composición farmacéutica que contiene un compuesto de fórmula (I), donde dicha composición es un comprimido o cápsula, o una formulación para aplicaciones tópicas. Estas composiciones son de utilidad para reducir la secreción de sebo (como seborrea, caspa, piel o cabello graso, cabello cano), como también para prevenir el acné.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/001,144 US5369126A (en) | 1993-01-06 | 1993-01-06 | Nonatetraenoic acid derivative for use in treating acne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY23707A1 true UY23707A1 (es) | 1994-06-05 |
Family
ID=21694605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY23707A UY23707A1 (es) | 1993-01-06 | 1993-12-31 | Procedimiento para la preparacion de derivados del acido nonatetraenoico |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5369126A (es) |
| EP (1) | EP0606614B1 (es) |
| JP (1) | JP2563158B2 (es) |
| KR (1) | KR940018351A (es) |
| CN (1) | CN1098086A (es) |
| AT (1) | ATE150442T1 (es) |
| AU (1) | AU668239B2 (es) |
| BR (1) | BR9400020A (es) |
| CA (1) | CA2110336A1 (es) |
| CZ (1) | CZ2194A3 (es) |
| DE (1) | DE69309029T2 (es) |
| DK (1) | DK0606614T3 (es) |
| ES (1) | ES2099894T3 (es) |
| FI (1) | FI940040A (es) |
| GR (1) | GR3023582T3 (es) |
| HU (1) | HUT65945A (es) |
| IL (1) | IL108246A (es) |
| MX (1) | MX9400200A (es) |
| NO (1) | NO180534C (es) |
| NZ (1) | NZ250581A (es) |
| PL (1) | PL301783A1 (es) |
| TW (1) | TW247311B (es) |
| UY (1) | UY23707A1 (es) |
| ZA (1) | ZA939805B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4233297A (en) * | 1996-08-23 | 1998-03-06 | Arch Development Corporation | Identification of activators and inhibitors of sebum formation |
| US6294188B1 (en) | 1998-07-09 | 2001-09-25 | Aviana Biopharm Inc. | Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women |
| US20140014137A1 (en) | 2009-09-18 | 2014-01-16 | Ecolab Usa Inc. | Treatment of non-trans fats with acidic tetra sodium l-glutamic acid, n, n-diacetic acid (glda) |
| MX364819B (es) * | 2009-09-18 | 2019-05-08 | Ecolab Usa Inc | Tratamiento de manchas de grasas no trans, acidos grasos y filtro solar con un agente quelatador. |
| US10253281B2 (en) | 2012-08-20 | 2019-04-09 | Ecolab Usa Inc. | Method of washing textile articles |
| CN107208006A (zh) | 2015-01-29 | 2017-09-26 | 艺康美国股份有限公司 | 用于处理织物中的污染的组合物和方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA854828B (en) * | 1984-07-27 | 1986-03-26 | Hoffmann La Roche | Phenyl nonatetraenoic acid derivatives |
| US4648996A (en) * | 1984-07-27 | 1987-03-10 | Hoffmann-La Roche Inc. | Phenyl substituted-2,4,6,8-nonatetraenoic acid |
-
1993
- 1993-01-06 US US08/001,144 patent/US5369126A/en not_active Expired - Fee Related
- 1993-11-25 TW TW082109941A patent/TW247311B/zh active
- 1993-11-30 CA CA002110336A patent/CA2110336A1/en not_active Abandoned
- 1993-12-15 AU AU52432/93A patent/AU668239B2/en not_active Ceased
- 1993-12-18 DK DK93120467.1T patent/DK0606614T3/da active
- 1993-12-18 DE DE69309029T patent/DE69309029T2/de not_active Expired - Fee Related
- 1993-12-18 EP EP93120467A patent/EP0606614B1/en not_active Expired - Lifetime
- 1993-12-18 AT AT93120467T patent/ATE150442T1/de not_active IP Right Cessation
- 1993-12-18 ES ES93120467T patent/ES2099894T3/es not_active Expired - Lifetime
- 1993-12-23 NZ NZ250581A patent/NZ250581A/en unknown
- 1993-12-30 JP JP5354100A patent/JP2563158B2/ja not_active Expired - Lifetime
- 1993-12-30 ZA ZA939805A patent/ZA939805B/xx unknown
- 1993-12-31 IL IL108246A patent/IL108246A/xx not_active IP Right Cessation
- 1993-12-31 UY UY23707A patent/UY23707A1/es unknown
-
1994
- 1994-01-03 HU HU9400001A patent/HUT65945A/hu unknown
- 1994-01-03 MX MX9400200A patent/MX9400200A/es not_active IP Right Cessation
- 1994-01-05 KR KR1019940000092A patent/KR940018351A/ko not_active Application Discontinuation
- 1994-01-05 NO NO940034A patent/NO180534C/no unknown
- 1994-01-05 PL PL94301783A patent/PL301783A1/xx unknown
- 1994-01-05 BR BR9400020A patent/BR9400020A/pt not_active Application Discontinuation
- 1994-01-05 FI FI940040A patent/FI940040A/fi unknown
- 1994-01-05 CN CN94100183A patent/CN1098086A/zh active Pending
- 1994-01-05 CZ CZ9421A patent/CZ2194A3/cs unknown
-
1997
- 1997-05-29 GR GR970401230T patent/GR3023582T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69309029T2 (de) | 1997-10-30 |
| US5369126A (en) | 1994-11-29 |
| HU9400001D0 (en) | 1994-05-30 |
| PL301783A1 (en) | 1994-07-11 |
| FI940040A (fi) | 1994-07-07 |
| IL108246A0 (en) | 1994-04-12 |
| IL108246A (en) | 1997-06-10 |
| NO940034D0 (no) | 1994-01-05 |
| NZ250581A (en) | 1995-12-21 |
| NO180534B (no) | 1997-01-27 |
| MX9400200A (es) | 1994-07-29 |
| KR940018351A (ko) | 1994-08-16 |
| JP2563158B2 (ja) | 1996-12-11 |
| ZA939805B (en) | 1994-07-06 |
| EP0606614A1 (en) | 1994-07-20 |
| CA2110336A1 (en) | 1994-07-07 |
| HUT65945A (en) | 1994-08-29 |
| DE69309029D1 (de) | 1997-04-24 |
| ATE150442T1 (de) | 1997-04-15 |
| GR3023582T3 (en) | 1997-08-29 |
| AU668239B2 (en) | 1996-04-26 |
| NO180534C (no) | 1997-05-07 |
| BR9400020A (pt) | 1994-08-16 |
| ES2099894T3 (es) | 1997-06-01 |
| TW247311B (es) | 1995-05-11 |
| NO940034L (es) | 1994-07-07 |
| DK0606614T3 (da) | 1997-09-22 |
| EP0606614B1 (en) | 1997-03-19 |
| JPH06234698A (ja) | 1994-08-23 |
| CZ2194A3 (en) | 1994-07-13 |
| CN1098086A (zh) | 1995-02-01 |
| AU5243293A (en) | 1994-07-14 |
| FI940040A0 (fi) | 1994-01-05 |
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