FI953994A0 - Menetelmä (-)-N-metyyli-N-(4-(4-fenyyli-4-asetyyliaminopiperidiini-1-yl)-2-(3,4-diklorofenyyli)butyyli)bentsamidi ja sen farmaseuttisesti hyväksyttäviä suoloja - Google Patents

Menetelmä (-)-N-metyyli-N-(4-(4-fenyyli-4-asetyyliaminopiperidiini-1-yl)-2-(3,4-diklorofenyyli)butyyli)bentsamidi ja sen farmaseuttisesti hyväksyttäviä suoloja

Info

Publication number
FI953994A0
FI953994A0 FI953994A FI953994A FI953994A0 FI 953994 A0 FI953994 A0 FI 953994A0 FI 953994 A FI953994 A FI 953994A FI 953994 A FI953994 A FI 953994A FI 953994 A0 FI953994 A0 FI 953994A0
Authority
FI
Finland
Prior art keywords
benzamide
dichlorophenyl
phenyl
methyl
pharmaceutically acceptable
Prior art date
Application number
FI953994A
Other languages
English (en)
Swedish (sv)
Other versions
FI953994A (fi
FI116221B (fi
Inventor
Marcel Descamps
Joel Radisson
Gilles Anne-Archard
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI953994A0 publication Critical patent/FI953994A0/fi
Publication of FI953994A publication Critical patent/FI953994A/fi
Application granted granted Critical
Publication of FI116221B publication Critical patent/FI116221B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI953994A 1994-08-24 1995-08-24 Menetelmä (-)-N-metyyli-N-[4-(4-fenyyli-4-asetyyliaminopiperidin-1-yyli)-2-(3,4-dikloorifenyyli)butyyli]bentsamidin ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi FI116221B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/294,035 US5512680A (en) 1993-02-26 1994-08-24 Process for the preparation of an optically pure aminoalcohol
US29403594 1994-08-24

Publications (3)

Publication Number Publication Date
FI953994A0 true FI953994A0 (fi) 1995-08-24
FI953994A FI953994A (fi) 1996-02-25
FI116221B FI116221B (fi) 2005-10-14

Family

ID=23131621

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953994A FI116221B (fi) 1994-08-24 1995-08-24 Menetelmä (-)-N-metyyli-N-[4-(4-fenyyli-4-asetyyliaminopiperidin-1-yyli)-2-(3,4-dikloorifenyyli)butyyli]bentsamidin ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi

Country Status (24)

Country Link
US (2) US5512680A (fi)
EP (1) EP0698601B1 (fi)
JP (1) JP3037592B2 (fi)
KR (1) KR100275978B1 (fi)
AT (1) ATE172964T1 (fi)
AU (1) AU685971B2 (fi)
BR (1) BR9503776A (fi)
CA (1) CA2156764C (fi)
CZ (1) CZ289654B6 (fi)
DE (1) DE69505756T2 (fi)
DK (1) DK0698601T3 (fi)
ES (1) ES2125574T3 (fi)
FI (1) FI116221B (fi)
HU (1) HU218485B (fi)
IL (1) IL114866A (fi)
MY (1) MY116365A (fi)
NO (1) NO305167B1 (fi)
NZ (1) NZ272827A (fi)
PL (1) PL182914B1 (fi)
RU (1) RU2097376C1 (fi)
SI (1) SI0698601T1 (fi)
SK (1) SK281454B6 (fi)
TW (1) TW410223B (fi)
ZA (1) ZA957025B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792835B3 (fr) * 1999-04-27 2001-05-25 Sanofi Sa Utilisation du saredutant pour la preparation de medicaments utiles dans le traitement ou la prevention de l'ensemble des troubles de l'humeur, des troubles de l'adaptation ou des troubles mixtes anxiete-depression
WO2007020079A2 (en) * 2005-08-17 2007-02-22 Synthon B.V. Orally disintegratable simvastatin tablets
JP2009191006A (ja) * 2008-02-14 2009-08-27 Sumitomo Chemical Co Ltd 光学活性な４−アミノ−３−（３，４−ジクロロフェニル）ブタン−１−オールの製造方法およびその中間体
EP3322691A4 (en) 2015-07-13 2019-03-27 Piramal Enterprises Limited IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE903957A1 (en) * 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
FR2676054B1 (fr) 1991-05-03 1993-09-03 Sanofi Elf Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2688219B1 (fr) 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
US5391819A (en) * 1992-09-30 1995-02-21 Merck & Co., Inc. Process of making chiral 2-aryl-1,4-butanediamine derivatives as useful neurokinin-A antagonists
FR2701946B1 (fr) * 1993-02-26 1995-05-24 Sanofi Elf Procédé pour la préparation d'un aminoalcool optiquement pur.

Also Published As

Publication number Publication date
DE69505756D1 (de) 1998-12-10
HU218485B (hu) 2000-09-28
FI953994A (fi) 1996-02-25
AU685971B2 (en) 1998-01-29
IL114866A (en) 1999-12-22
ATE172964T1 (de) 1998-11-15
MY116365A (en) 2004-01-31
NZ272827A (en) 1997-11-24
EP0698601B1 (en) 1998-11-04
DK0698601T3 (da) 1999-07-19
HUT74184A (en) 1996-11-28
CA2156764C (en) 2006-06-13
US5780666A (en) 1998-07-14
CA2156764A1 (en) 1996-02-25
US5512680A (en) 1996-04-30
BR9503776A (pt) 1996-04-16
NO305167B1 (no) 1999-04-12
TW410223B (en) 2000-11-01
JP3037592B2 (ja) 2000-04-24
EP0698601A1 (en) 1996-02-28
HU9502481D0 (en) 1995-10-30
IL114866A0 (en) 1995-12-08
CZ216495A3 (en) 1996-03-13
JPH08176108A (ja) 1996-07-09
RU2097376C1 (ru) 1997-11-27
AU3021695A (en) 1996-03-07
SK281454B6 (sk) 2001-03-12
ES2125574T3 (es) 1999-03-01
ZA957025B (en) 1996-03-26
KR100275978B1 (ko) 2000-12-15
FI116221B (fi) 2005-10-14
SI0698601T1 (en) 1999-04-30
SK103095A3 (en) 1996-03-06
CZ289654B6 (cs) 2002-03-13
KR960007562A (ko) 1996-03-22
PL182914B1 (pl) 2002-04-30
PL310155A1 (en) 1996-03-04
NO953313D0 (no) 1995-08-23
DE69505756T2 (de) 1999-05-27
NO953313L (no) 1996-02-26

Similar Documents

Publication Publication Date Title
DE69831868D1 (en) Antithrombosemittel
ATE297203T1 (de) Antithrombotische mitteln
NO932442D0 (no) Anvendelse av 1,3-oksatiolannukleosidanaloger ved behandling av hepatitt b
HUT59109A (en) Process for producing hydroxymethyl-(methylenecyclopentyl)-purines and -pyrimidines, their pharmaceutically acceptable salts and pharmaceutical compositions comprising same
BR9503536A (pt) Composto processo para sua preparação seu uso e composição farmacêutica
AU6735894A (en) Use of phenalkylamines
FI953994A0 (fi) Menetelmä (-)-N-metyyli-N-(4-(4-fenyyli-4-asetyyliaminopiperidiini-1-yl)-2-(3,4-diklorofenyyli)butyyli)bentsamidi ja sen farmaseuttisesti hyväksyttäviä suoloja
NO933837L (no) 4-aryl-3-(heteroarylureido)kinolin-derivater
BR9400020A (pt) Composto, processo para sua preparação, composicões farmacêuticas e uso
MY130190A (en) Method for the preparation of 4-halo-2'- nitrobutyrophenone compounds
MX9205408A (es) Metodo para tratar hipertension.
EP0245004A3 (en) Antihypercholesterolemic compounds
NO306673B1 (no) Mellomprodukt for fremstilling av farmasöytisk aktiv forbindelse
IES950207A2 (en) Process for the resolution of racemic 3-(2-pyridyl)-3-phenyl-N,N-dimethylpropylamines

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: SANOFI-AVENTIS

FG Patent granted

Ref document number: 116221

Country of ref document: FI

MM Patent lapsed