BG25079A3 - Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(2'-нитрофенил)-1,4 дихидропиридин-5-карбоновата киселина - Google Patents
Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(2'-нитрофенил)-1,4 дихидропиридин-5-карбоновата киселинаInfo
- Publication number
- BG25079A3 BG25079A3 BG035342A BG3534276A BG25079A3 BG 25079 A3 BG25079 A3 BG 25079A3 BG 035342 A BG035342 A BG 035342A BG 3534276 A BG3534276 A BG 3534276A BG 25079 A3 BG25079 A3 BG 25079A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- dihydropyridine
- methoxycarbonyl
- nitrophenyl
- dimethyl
- obtaining
- Prior art date
Links
- ZYVYEJXMYBUCMN-UHFFFAOYSA-N 1-methoxy-2-methylpropane Chemical class COCC(C)C ZYVYEJXMYBUCMN-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2549568A DE2549568C3 (de) | 1975-11-05 | 1975-11-05 | 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG25079A3 true BG25079A3 (bg) | 1978-07-12 |
Family
ID=5960951
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG035342A BG25079A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(2'-нитрофенил)-1,4 дихидропиридин-5-карбоновата киселина |
| BG035343A BG24803A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина |
| BG035341A BG25078A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина |
| BG035345A BG24805A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина |
| BG035344A BG24804A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина |
| BG034575A BG24668A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2-6-диметил-3- метоксикарбонил-4-(2'-нитрофенил)-1,4-дихидропиридин-5- карбоновата киселина |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG035343A BG24803A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина |
| BG035341A BG25078A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина |
| BG035345A BG24805A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина |
| BG035344A BG24804A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина |
| BG034575A BG24668A3 (bg) | 1975-11-05 | 1976-11-01 | Метод за получаване на изобутилов естер на 2-6-диметил-3- метоксикарбонил-4-(2'-нитрофенил)-1,4-дихидропиридин-5- карбоновата киселина |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS5259161A (enExample) |
| AT (1) | AT352129B (enExample) |
| AU (1) | AU498964B2 (enExample) |
| BE (1) | BE847968A (enExample) |
| BG (6) | BG25079A3 (enExample) |
| CA (1) | CA1085406A (enExample) |
| CH (2) | CH623038A5 (enExample) |
| CS (1) | CS200499B2 (enExample) |
| DE (1) | DE2549568C3 (enExample) |
| DK (1) | DK146762C (enExample) |
| ES (2) | ES452986A1 (enExample) |
| FI (1) | FI60704C (enExample) |
| FR (1) | FR2330395A1 (enExample) |
| GB (1) | GB1516793A (enExample) |
| GR (1) | GR61241B (enExample) |
| HK (1) | HK12681A (enExample) |
| IE (1) | IE43984B1 (enExample) |
| IL (1) | IL50817A (enExample) |
| LU (2) | LU76133A1 (enExample) |
| NL (2) | NL175915C (enExample) |
| NO (1) | NO145574C (enExample) |
| NZ (1) | NZ182502A (enExample) |
| PL (2) | PL106084B1 (enExample) |
| PT (1) | PT65797B (enExample) |
| RO (1) | RO70295A (enExample) |
| SE (1) | SE423542B (enExample) |
| ZA (1) | ZA766622B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146630A (en) * | 1976-11-12 | 1979-03-27 | Boehringer Mannheim Gmbh | Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers |
| JPS55301A (en) * | 1978-02-14 | 1980-01-05 | Yamanouchi Pharmaceut Co Ltd | 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation |
| DE3212736A1 (de) * | 1982-04-06 | 1983-10-13 | Bayer Ag, 5090 Leverkusen | Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung |
| DE3222367A1 (de) * | 1982-06-15 | 1983-12-15 | Bayer Ag, 5090 Leverkusen | Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung |
| JPS5982192U (ja) * | 1982-11-27 | 1984-06-02 | エムケ−精工株式会社 | 扉 |
| DE3312216A1 (de) * | 1983-04-05 | 1984-10-11 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern |
| DE3312283A1 (de) * | 1983-04-05 | 1984-10-18 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern |
| US4794111A (en) * | 1984-05-23 | 1988-12-27 | Bayer Aktiengesellschaft | Dihydropyridine preparations containing β-blockers |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
-
1975
- 1975-11-05 DE DE2549568A patent/DE2549568C3/de not_active Expired
-
1976
- 1976-10-22 NO NO763608A patent/NO145574C/no unknown
- 1976-10-29 JP JP51129540A patent/JPS5259161A/ja active Granted
- 1976-11-01 BG BG035342A patent/BG25079A3/xx unknown
- 1976-11-01 BG BG035343A patent/BG24803A3/xx unknown
- 1976-11-01 BG BG035341A patent/BG25078A3/xx unknown
- 1976-11-01 BG BG035345A patent/BG24805A3/xx unknown
- 1976-11-01 BG BG035344A patent/BG24804A3/xx unknown
- 1976-11-01 BG BG034575A patent/BG24668A3/xx unknown
- 1976-11-02 NZ NZ182502A patent/NZ182502A/xx unknown
- 1976-11-02 GB GB45501/76A patent/GB1516793A/en not_active Expired
- 1976-11-02 RO RO7688294A patent/RO70295A/ro unknown
- 1976-11-02 CH CH1381976A patent/CH623038A5/de not_active IP Right Cessation
- 1976-11-02 IL IL50817A patent/IL50817A/xx unknown
- 1976-11-02 CS CS767068A patent/CS200499B2/cs unknown
- 1976-11-03 NL NLAANVRAGE7612198,A patent/NL175915C/xx not_active IP Right Cessation
- 1976-11-03 AT AT814276A patent/AT352129B/de not_active IP Right Cessation
- 1976-11-03 FI FI763160A patent/FI60704C/fi not_active IP Right Cessation
- 1976-11-03 PL PL1976193438A patent/PL106084B1/pl unknown
- 1976-11-03 PL PL1976201800A patent/PL105940B1/pl unknown
- 1976-11-04 PT PT65797A patent/PT65797B/pt unknown
- 1976-11-04 SE SE7612308A patent/SE423542B/xx not_active IP Right Cessation
- 1976-11-04 ES ES452986A patent/ES452986A1/es not_active Expired
- 1976-11-04 IE IE2458/76A patent/IE43984B1/en not_active IP Right Cessation
- 1976-11-04 BE BE172063A patent/BE847968A/xx not_active IP Right Cessation
- 1976-11-04 ZA ZA766622A patent/ZA766622B/xx unknown
- 1976-11-04 LU LU76133A patent/LU76133A1/xx active Protection Beyond IP Right Term
- 1976-11-04 LU LU88275C patent/LU88275I2/xx unknown
- 1976-11-04 GR GR52093A patent/GR61241B/el unknown
- 1976-11-04 CA CA264,921A patent/CA1085406A/en not_active Expired
- 1976-11-04 DK DK498476A patent/DK146762C/da not_active IP Right Cessation
- 1976-11-05 AU AU19358/76A patent/AU498964B2/en not_active Expired
- 1976-11-05 FR FR7633488A patent/FR2330395A1/fr active Granted
-
1977
- 1977-10-13 ES ES463166A patent/ES463166A1/es not_active Expired
-
1980
- 1980-07-23 CH CH567880A patent/CH622779A5/de not_active IP Right Cessation
-
1981
- 1981-04-02 HK HK126/81A patent/HK12681A/xx unknown
-
1993
- 1993-05-24 NL NL930035C patent/NL930035I2/nl unknown
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