BG25078A3 - A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid - Google Patents

A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid

Info

Publication number
BG25078A3
BG25078A3 BG035341A BG3534176A BG25078A3 BG 25078 A3 BG25078 A3 BG 25078A3 BG 035341 A BG035341 A BG 035341A BG 3534176 A BG3534176 A BG 3534176A BG 25078 A3 BG25078 A3 BG 25078A3
Authority
BG
Bulgaria
Prior art keywords
dichidropiridin
metoxycarbonyl
nitrophenyl
dimethyl
obtaining
Prior art date
Application number
BG035341A
Other languages
Bulgarian (bg)
English (en)
Inventor
Egbert Wehinger
Friedrich Bossert
Arend Heise
Stanislav Karda
Kurt Stoepel
Walle Vater
Original Assignee
Неизвестен
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Неизвестен filed Critical Неизвестен
Publication of BG25078A3 publication Critical patent/BG25078A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG035341A 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid BG25078A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG25078A3 true BG25078A3 (en) 1978-07-12

Family

ID=5960951

Family Applications (6)

Application Number Title Priority Date Filing Date
BG035341A BG25078A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG034575A BG24668A3 (en) 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid
BG035342A BG25079A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG035344A BG24804A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Family Applications After (5)

Application Number Title Priority Date Filing Date
BG035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG034575A BG24668A3 (en) 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid
BG035342A BG25079A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG035344A BG24804A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Country Status (27)

Country Link
JP (1) JPS5259161A (pt)
AT (1) AT352129B (pt)
AU (1) AU498964B2 (pt)
BE (1) BE847968A (pt)
BG (6) BG25078A3 (pt)
CA (1) CA1085406A (pt)
CH (2) CH623038A5 (pt)
CS (1) CS200499B2 (pt)
DE (1) DE2549568C3 (pt)
DK (1) DK146762C (pt)
ES (2) ES452986A1 (pt)
FI (1) FI60704C (pt)
FR (1) FR2330395A1 (pt)
GB (1) GB1516793A (pt)
GR (1) GR61241B (pt)
HK (1) HK12681A (pt)
IE (1) IE43984B1 (pt)
IL (1) IL50817A (pt)
LU (2) LU76133A1 (pt)
NL (2) NL175915C (pt)
NO (1) NO145574C (pt)
NZ (1) NZ182502A (pt)
PL (2) PL105940B1 (pt)
PT (1) PT65797B (pt)
RO (1) RO70295A (pt)
SE (1) SE423542B (pt)
ZA (1) ZA766622B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2549568A1 (de) 1977-05-18
IE43984L (en) 1977-05-05
PT65797B (de) 1978-05-12
AU1935876A (en) 1978-05-11
BG24805A3 (en) 1978-05-12
DE2549568C3 (de) 1981-10-29
AT352129B (de) 1979-09-10
ATA814276A (de) 1979-02-15
HK12681A (en) 1981-04-10
FI60704C (fi) 1982-03-10
GB1516793A (en) 1978-07-05
SE7612308L (sv) 1977-05-06
NO145574B (no) 1982-01-11
DK146762B (da) 1983-12-27
BG24804A3 (en) 1978-05-12
NO145574C (no) 1982-04-21
FI60704B (fi) 1981-11-30
FI763160A (pt) 1977-05-06
LU76133A1 (pt) 1977-06-02
BE847968A (fr) 1977-05-04
SE423542B (sv) 1982-05-10
BG24668A3 (en) 1978-04-12
IL50817A (en) 1979-07-25
JPS5647185B2 (pt) 1981-11-07
NL930035I1 (nl) 1993-08-02
PL106084B1 (pl) 1979-11-30
CH623038A5 (en) 1981-05-15
PT65797A (de) 1976-12-01
NO763608L (pt) 1977-05-06
GR61241B (en) 1978-10-12
NL175915C (nl) 1985-01-16
FR2330395B1 (pt) 1978-12-22
JPS5259161A (en) 1977-05-16
BG24803A3 (en) 1978-05-12
CA1085406A (en) 1980-09-09
ZA766622B (en) 1977-10-26
IE43984B1 (en) 1981-07-15
NZ182502A (en) 1978-07-28
CS200499B2 (en) 1980-09-15
IL50817A0 (en) 1977-01-31
PL105940B1 (pl) 1979-11-30
DE2549568B2 (de) 1980-08-21
BG25079A3 (en) 1978-07-12
ES452986A1 (es) 1977-12-16
DK146762C (da) 1984-06-12
NL7612198A (nl) 1977-05-09
AU498964B2 (en) 1979-03-29
FR2330395A1 (fr) 1977-06-03
DK498476A (da) 1977-05-06
NL930035I2 (nl) 1993-10-01
RO70295A (ro) 1981-08-17
ES463166A1 (es) 1978-07-16
LU88275I2 (pt) 1994-02-03
CH622779A5 (en) 1981-04-30

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