BE2015C041I2 - - Google Patents
Download PDFInfo
- Publication number
- BE2015C041I2 BE2015C041I2 BE2015C041C BE2015C041C BE2015C041I2 BE 2015C041 I2 BE2015C041 I2 BE 2015C041I2 BE 2015C041 C BE2015C041 C BE 2015C041C BE 2015C041 C BE2015C041 C BE 2015C041C BE 2015C041 I2 BE2015C041 I2 BE 2015C041I2
- Authority
- BE
- Belgium
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0417487.6A GB0417487D0 (en) | 2004-08-05 | 2004-08-05 | Organic compound |
Publications (1)
Publication Number | Publication Date |
---|---|
BE2015C041I2 true BE2015C041I2 (enrdf_load_html_response) | 2024-10-08 |
Family
ID=32982602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE2015C041C BE2015C041I2 (enrdf_load_html_response) | 2004-08-05 | 2015-07-07 |
Country Status (40)
Families Citing this family (157)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
GB0417487D0 (en) * | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
GB0425569D0 (en) | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Biological products |
HRP20100014T1 (hr) * | 2005-09-01 | 2010-02-28 | Schering Corporation | Uporaba il-23 i il-17 antagonista u liječenju autoimune očne upalne bolesti |
RS52509B2 (sr) * | 2005-12-13 | 2020-09-30 | Lilly Co Eli | Anti-il-17 antitela |
EP2913343B1 (en) | 2005-12-20 | 2018-08-08 | SBI Biotech Co., Ltd. | Anti-ILT7 antibody |
AR060017A1 (es) | 2006-01-13 | 2008-05-21 | Novartis Ag | Composiciones y metodos de uso para anticuerpos de dickkopf -1 |
RU2430110C2 (ru) | 2006-01-31 | 2011-09-27 | Новартис Аг | Антитела - антагонисты интерлейкина-17 (ил-17) для лечения рака |
US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
WO2007147019A2 (en) | 2006-06-13 | 2007-12-21 | Zymogenetics, Inc. | Il-17 and il-23 antagonists and methods of using the same |
TW200815469A (en) | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
GB0612928D0 (en) * | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
MX2009001620A (es) * | 2006-08-11 | 2009-02-23 | Schering Corp | Anticuerpos para il-17a. |
GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
TWI426918B (zh) | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
EP2417974A1 (en) | 2007-02-28 | 2012-02-15 | Schering Corporation | Combination therapy for treatment of immune disorders |
KR101591533B1 (ko) | 2007-05-29 | 2016-02-03 | 노파르티스 아게 | 항-il-1-베타 치료법에 대한 신규 적응증 |
CA2690568A1 (en) * | 2007-06-20 | 2008-12-24 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
US20110091378A1 (en) * | 2007-07-23 | 2011-04-21 | Paul Dudas | Methods and Compositions for Treating Fibrosis Related Disorders Using IL-17 Antagonists |
US20110195509A1 (en) * | 2007-09-06 | 2011-08-11 | Drew Pardoll | Treatment of th17-mediated autoimmune disease via inhibition of stat 3 |
WO2009072802A2 (en) * | 2007-12-03 | 2009-06-11 | Amorepacific Corporation | Composition for slimming |
WO2009082624A2 (en) * | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
JP5886523B2 (ja) | 2008-01-09 | 2016-03-16 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | 眼の炎症性障害を処置するための治療組成物 |
GB0807413D0 (en) * | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
UA102097C2 (ru) * | 2008-04-29 | 2013-06-10 | Амген Рисерч (Мюнхен) ГмбХ | Способ лечения воспалительного заболевания с применением соединения, которое нейтрализует gm-csf, и соединения, которое нейтрализует il-17 |
EP2282769A4 (en) | 2008-04-29 | 2012-04-25 | Abbott Lab | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES |
KR20110025649A (ko) | 2008-05-05 | 2011-03-10 | 노비뮨 에스 에이 | 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법 |
TW201006485A (en) | 2008-06-03 | 2010-02-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
EP2297209A4 (en) | 2008-06-03 | 2012-08-01 | Abbott Lab | IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF |
AU2009268585C1 (en) | 2008-07-08 | 2014-10-02 | Abbvie Inc. | Prostaglandin E2 dual variable domain immunoglobulins and uses thereof |
WO2010034443A1 (en) | 2008-09-29 | 2010-04-01 | F. Hoffmann-La Roche Ag | Antibodies against human il 17 and uses thereof |
NZ594514A (en) | 2009-03-05 | 2013-06-28 | Abbott Lab | Interleukin-17 BINDING PROTEINS |
PE20120532A1 (es) * | 2009-04-27 | 2012-05-18 | Novartis Ag | ANTICUERPOS ANTI-ActRIIB |
PE20160652A1 (es) | 2009-05-05 | 2016-07-09 | Novimmune Sa | Anticuerpos que se unen a il-17f |
RU2012112550A (ru) | 2009-09-01 | 2013-10-10 | Эбботт Лэборетриз | Иммуноглобулины с двумя вариабельными доменами и их применение |
EP2485763A4 (en) * | 2009-10-10 | 2013-10-30 | Univ Leland Stanford Junior | CYTOKINE COMPOSITIONS OF THE IL-17 FAMILY AND ITS USES |
UY32948A (es) | 2009-10-15 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
NZ599737A (en) | 2009-10-30 | 2015-02-27 | Janssen Biotech Inc | Il-17a antagonists |
US9932403B2 (en) | 2010-05-20 | 2018-04-03 | Ablynx Nv | Biological materials related to HER3 |
SG188190A1 (en) | 2010-08-03 | 2013-04-30 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
NZ607615A (en) | 2010-08-05 | 2015-03-27 | Anaptysbio Inc | Antibodies directed against il-17 |
CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
AU2011293253B2 (en) | 2010-08-26 | 2014-12-11 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
WO2012045082A2 (en) | 2010-10-01 | 2012-04-05 | Jason Schrum | Engineered nucleic acids and methods of use thereof |
HRP20180301T1 (hr) * | 2010-10-08 | 2018-03-23 | Novartis Ag | Postupci liječenja psorijaze uporabom il-17 antagonista |
CN104800844A (zh) * | 2010-11-05 | 2015-07-29 | 诺华有限公司 | 使用il-17拮抗剂治疗类风湿性关节炎的方法 |
AU2014259523B2 (en) * | 2010-11-05 | 2016-02-04 | Novartis Ag | Methods of treating psoriatic arthritis using IL-17 antagonists |
TW201307845A (zh) | 2010-12-13 | 2013-02-16 | Novartis Ag | 預測方法及利用il-17拮抗劑治療關節炎的方法 |
GB201100282D0 (en) | 2011-01-07 | 2011-02-23 | Ucb Pharma Sa | Biological methods |
JP5947041B2 (ja) * | 2011-01-07 | 2016-07-06 | 第一三共ヘルスケア株式会社 | 安全なil−17産生抑制剤 |
US10208349B2 (en) | 2011-01-07 | 2019-02-19 | Ucb Biopharma Sprl | Lipocalin 2 as a biomarker for IL-17 inhibitor therapy efficacy |
EP2663869A1 (en) * | 2011-01-13 | 2013-11-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for predicting the risk of having a cardiovascular event in a subject |
LT2663577T (lt) | 2011-01-14 | 2017-07-25 | Ucb Biopharma Sprl | Antikūnas, surišantis il-17a ir il-17f |
WO2012125680A1 (en) | 2011-03-16 | 2012-09-20 | Novartis Ag | Methods of treating vasculitis using an il-17 binding molecule |
CA2831787A1 (en) * | 2011-03-29 | 2012-10-04 | Glaxosmithkline Llc | Buffer system for protein purification |
CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
UA117218C2 (uk) | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
HUE057725T2 (hu) | 2011-10-03 | 2022-06-28 | Modernatx Inc | Módosított nukleozidok, nukleotidok és nukleinsavak és ezek felhasználása |
KR20140097178A (ko) * | 2011-11-21 | 2014-08-06 | 노파르티스 아게 | IL-17 길항제 및 건선성 관절염 (PsA) 반응 또는 비-반응 대립유전자를 이용하여 PsA를 치료하는 방법 |
AP2014007680A0 (en) | 2011-12-02 | 2014-06-30 | Novartis Ag | Anti-1L-beta (interleukin-1beta) antibody-based prophylactic therapy to prevent complications leading to vaso-occlusion in sickle cell disease |
US20140359902A1 (en) | 2011-12-16 | 2014-12-04 | Synthon Biopharmaceuticals B.V. | EXPRESSION OF SECRETORY IgA ANTIBODIES IN DUCKWEED |
CA2859387A1 (en) | 2011-12-16 | 2013-06-20 | Moderna Therapeutics, Inc. | Modified nucleoside, nucleotide, and nucleic acid compositions |
UY34558A (es) | 2011-12-30 | 2013-07-31 | Abbvie Inc | Proteínas de unión específicas duales dirigidas contra il-13 y/o il-17 |
US9284283B2 (en) | 2012-02-02 | 2016-03-15 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating IL-17 |
DE18203666T1 (de) | 2012-04-02 | 2021-10-07 | Modernatx, Inc. | Modifizierte polynukleotide zur herstellung von sekretierten proteinen |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
EP2834273B1 (en) | 2012-04-05 | 2018-08-22 | F.Hoffmann-La Roche Ag | Bispecific antibodies against human tweak and human il17 and uses thereof |
CN104244979A (zh) | 2012-04-20 | 2014-12-24 | 诺华股份有限公司 | 使用il-17拮抗剂治疗强直性脊柱炎的方法 |
TWI609882B (zh) | 2012-05-22 | 2018-01-01 | 必治妥美雅史谷比公司 | 雙特異性抗體及其使用方法 |
AR093297A1 (es) | 2012-10-31 | 2015-05-27 | Amgen Res (Munich) Gmbh | Formulacion liquida que comprende un compuesto neutralizante de gm-csf |
JP6339578B2 (ja) | 2012-10-31 | 2018-06-06 | タケダ・ゲー・エム・ベー・ハーTakeda GmbH | Gm−csf中和化合物を含む凍結乾燥製剤 |
CN104884472B (zh) | 2012-11-01 | 2021-10-15 | 艾伯维公司 | 抗-vegf/dll4双重可变结构域免疫球蛋白及其用途 |
EP4074834A1 (en) | 2012-11-26 | 2022-10-19 | ModernaTX, Inc. | Terminally modified rna |
WO2014107737A2 (en) | 2013-01-07 | 2014-07-10 | Eleven Biotherapeutics, Inc. | Local delivery of il-17 inhibitors for treating ocular disease |
ES2758473T3 (es) | 2013-02-08 | 2020-05-05 | Novartis Ag | Anticuerpos anti-IL-17A y su uso en el tratamiento de trastornos autoinmunitarios e inflamatorios |
CN105324396A (zh) | 2013-03-15 | 2016-02-10 | 艾伯维公司 | 针对IL-1β和/或IL-17的双重特异性结合蛋白 |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
WO2014155278A2 (en) * | 2013-03-26 | 2014-10-02 | Novartis Ag | Methods of treating autoimmune diseases using il-17 antagonists |
WO2014161570A1 (en) | 2013-04-03 | 2014-10-09 | Roche Glycart Ag | Antibodies against human il17 and uses thereof |
US9707154B2 (en) | 2013-04-24 | 2017-07-18 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
US9603882B2 (en) | 2013-08-13 | 2017-03-28 | Industrial Technology Research Institute | Method for modulating Th17 cells and method for treating a disease related to modulation of Th17 cells |
JP6255099B2 (ja) * | 2013-08-15 | 2017-12-27 | ノバルティス アーゲー | Il−17アンタゴニストを使用して汎発性膿疱性乾癬(gpp)を処置する方法 |
CA2922251C (en) | 2013-08-30 | 2023-10-17 | Takeda Gmbh | Antibodies neutralizing gm-csf for use in the treatment of rheumatoid arthritis or as analgesics |
WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
CN105980401A (zh) | 2013-10-03 | 2016-09-28 | 现代治疗公司 | 编码低密度脂蛋白受体的多核苷酸 |
SI3072905T1 (sl) | 2013-11-18 | 2020-12-31 | Shanghai Hengrui Pharmaceutical Co., Ltd. | IL-17A-vezavno sredstvo in uporabe le-tega |
CN105916883B (zh) * | 2014-01-28 | 2019-12-03 | 北京韩美药品有限公司 | 双功能融合蛋白及其制备方法和用途 |
TWI713453B (zh) | 2014-06-23 | 2020-12-21 | 美商健生生物科技公司 | 干擾素α及ω抗體拮抗劑 |
SI3191120T1 (sl) | 2014-09-10 | 2024-10-30 | Novartis Ag | Uporaba antagonistov IL-17 za zaviranje napredovanja strukturne poškodbe pri pacientih s psoriatičnim artritisom |
RU2609627C2 (ru) | 2014-09-26 | 2017-02-02 | Закрытое Акционерное Общество "Биокад" | Высокоаффинные и агрегационно стабильные антитела на основе вариабельных доменов vl и производного vhh |
MA41044A (fr) | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
CN107001478B (zh) | 2014-10-14 | 2022-01-11 | 诺华股份有限公司 | 针对pd-l1的抗体分子及其用途 |
WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
AR103172A1 (es) * | 2014-12-22 | 2017-04-19 | Novartis Ag | Reducción selectiva de residuos de cisteina en anticuerpos il-17 |
KR102683288B1 (ko) | 2015-01-12 | 2024-07-11 | 애피바디 에이비 | Il-17a-결합 폴리펩티드 |
CN107407677B (zh) | 2015-01-28 | 2020-07-17 | 豪夫迈·罗氏有限公司 | 多发性硬化的基因表达标志和治疗 |
CN105315371B (zh) | 2015-03-05 | 2018-05-29 | 北京百特美博生物科技有限公司 | 抗人il-17单克隆抗体 |
TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
KR20180017145A (ko) | 2015-07-16 | 2018-02-20 | 일라이 릴리 앤드 캄파니 | 소양증의 치료 |
DK3317301T3 (da) | 2015-07-29 | 2021-06-28 | Immutep Sas | Kombinationsterapier omfattende antistofmolekyler mod lag-3 |
US20180207273A1 (en) | 2015-07-29 | 2018-07-26 | Novartis Ag | Combination therapies comprising antibody molecules to tim-3 |
EP4378957A3 (en) | 2015-07-29 | 2024-08-07 | Novartis AG | Combination therapies comprising antibody molecules to pd-1 |
IL297775A (en) | 2015-10-19 | 2022-12-01 | Novartis Ag | Methods of treating non-radiographic axial spondyloarthritis using interleukin-17 (il-17) antagonists |
KR102833068B1 (ko) | 2015-12-17 | 2025-07-14 | 노파르티스 아게 | Pd-1에 대한 항체 분자 및 그의 용도 |
KR102439395B1 (ko) | 2016-03-10 | 2022-09-05 | 비엘라 바이오, 인크. | Ilt7 결합 분자 및 이의 사용 방법 |
PL3426680T3 (pl) | 2016-03-10 | 2025-03-31 | Acceleron Pharma Inc. | Białka wiążące receptor aktywiny typu 2 i ich zastosowania |
RU2680011C2 (ru) | 2016-04-29 | 2019-02-14 | Закрытое Акционерное Общество "Биокад" | Триспецифические антитела против il-17a, il-17f и другой провоспалительной молекулы |
FR3051673B1 (fr) * | 2016-05-24 | 2018-06-22 | Assistance Publique - Hopitaux De Paris | Inhibiteurs de la voie de l'interleukine 17 pour le traitement des infections chroniques dues a hpv |
CN107488227A (zh) * | 2016-06-12 | 2017-12-19 | 三生国健药业(上海)股份有限公司 | 抗人白细胞介素‑17a单克隆抗体、其制备方法和应用 |
WO2017221174A1 (en) | 2016-06-22 | 2017-12-28 | Novartis Ag | Methods of treating vitiligo using interleukin-17 (il-17) antibodies |
ES2992409T3 (es) | 2016-07-19 | 2024-12-12 | Novartis Ag | Métodos de tratamiento de la psoriasis en placas de nueva aparición usando antagonistas de IL-17 |
EA201990673A1 (ru) | 2016-09-14 | 2019-08-30 | Бэйцзин Ханми Фарм. Ко., Лтд. | Антитела, специфически связывающиеся с il-17a, и их функциональные фрагменты |
WO2018096467A1 (en) | 2016-11-28 | 2018-05-31 | Novartis Ag | Methods of treating acne using interleukin-17 (il-17) antagonists |
JP6995127B2 (ja) | 2017-02-10 | 2022-02-04 | ジェネンテック, インコーポレイテッド | 抗トリプターゼ抗体、その組成物、及びその使用 |
WO2018158741A1 (en) | 2017-03-03 | 2018-09-07 | Novartis Ag | Psoriasis disease modification following long-term treatment with an il-17 antagonist |
US10676522B2 (en) | 2017-05-05 | 2020-06-09 | Novartis Ag | Methods of selectively treating asthma using IL-17 antagonists |
CN108359011B (zh) | 2017-07-21 | 2019-06-25 | 华博生物医药技术(上海)有限公司 | 靶向于白介素17a的抗体、其制备方法和应用 |
AU2018361975A1 (en) | 2017-11-02 | 2020-05-07 | Novartis Ag | Method of treating tendinopathy using interleukin-17 (IL-17) antagonists |
US20200277369A1 (en) | 2017-11-20 | 2020-09-03 | Novartis Ag | Method of treating hidradentitis suppurativa with il-17 antagonists |
WO2019108900A1 (en) | 2017-11-30 | 2019-06-06 | Novartis Ag | Bcma-targeting chimeric antigen receptor, and uses thereof |
EP3773717A4 (en) * | 2018-03-29 | 2022-05-11 | REMD Biotherapeutics, Inc. | TREATMENT OF AUTOIMMUNE AND INFLAMMATION DISEASES WITH ANTIBODIES THAT BIND INTERLEUKIN-17A (IL-17A). |
US11492409B2 (en) | 2018-06-01 | 2022-11-08 | Novartis Ag | Binding molecules against BCMA and uses thereof |
US12134644B2 (en) | 2018-07-31 | 2024-11-05 | Weiqun SHEN | Anti-IL-17A antibodies and use thereof |
EP3856772A1 (en) | 2018-09-25 | 2021-08-04 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Use of antagonists of th17 cytokines for the treatment of bronchial remodeling in patients suffering from allergic asthma |
EP3689907A1 (en) | 2019-01-31 | 2020-08-05 | Numab Therapeutics AG | Antibodies targeting il-17a and methods of use thereof |
CN120025437A (zh) | 2019-01-31 | 2025-05-23 | 努玛治疗有限公司 | 对TNFα和IL-17A具有特异性的多特异性抗体、靶向IL-17A的抗体及其使用方法 |
CN113474360B (zh) | 2019-02-18 | 2025-01-07 | 伊莱利利公司 | 治疗性抗体制剂 |
CN110179746A (zh) * | 2019-05-17 | 2019-08-30 | 通化东宝生物科技有限公司 | 一种稳定的苏金单抗注射剂及其制备方法 |
AU2020284114B2 (en) * | 2019-05-31 | 2025-06-26 | Fibrobiologics, Inc. | Concurrent activation of regenerative and tolerogenic processes by fibroblast-based compositions for the treatment of multiple sclerosis |
CN110343666B (zh) * | 2019-07-10 | 2023-05-30 | 通化东宝药业股份有限公司 | 一种cho细胞培养的补料培养基及其制备方法和应用 |
CA3148491C (en) | 2019-07-26 | 2023-08-01 | Sinocelltech Ltd | Humanized anti-il17a antibody and use thereof |
EP4006053A4 (en) | 2019-07-30 | 2022-10-26 | Jiangsu Hengrui Medicine Co., Ltd. | METHOD OF TREATMENT OF AN AUTOIMMUNE DISEASE WITH AN IL-17 ANTAGONIST |
BR112022004941A2 (pt) | 2019-09-20 | 2022-06-28 | Novartis Ag | Métodos para tratar doenças autoimunes com o uso de antagonistas de interleucina-17 (il-17) |
KR20220070244A (ko) * | 2019-09-25 | 2022-05-30 | 도꾜 다이가꾸 | 전신성 강피증 치료용 의약 조성물 |
WO2021067195A1 (en) | 2019-09-30 | 2021-04-08 | Janssen Biotech, Inc. | Compositions and methods for an il-17 target engagement assay with large molecule modulators |
AU2020386669A1 (en) | 2019-11-19 | 2022-06-02 | Novartis Ag | Methods of treating Lupus Nephritis using interleukin-17 (IL-17) antagonists |
JP2023504679A (ja) | 2019-12-06 | 2023-02-06 | ノバルティス アーゲー | インターロイキン-17(il-17)アンタゴニストを使用して扁平苔癬を治療する方法 |
CN114805577B (zh) * | 2019-12-31 | 2023-11-21 | 南京融捷康生物科技有限公司 | 针对il-17ra蛋白的抗体及其制备方法和应用 |
KR20230025890A (ko) | 2020-06-23 | 2023-02-23 | 노파르티스 아게 | 인터루킨-17(il-17) 길항제를 이용한 갑상선 안병증 및 그레이브스 안와병증의 치료 방법 |
UY39484A (es) | 2020-11-02 | 2022-06-30 | Novartis Ag | Inhibidores de interleucina-17 |
JP2023548529A (ja) | 2020-11-06 | 2023-11-17 | ノバルティス アーゲー | Cd19結合分子及びその使用 |
CA3202877A1 (en) | 2020-12-02 | 2022-06-09 | Fresenius Kabi Deutschland Gmbh | Methods of selectively reducing antibodies |
CN116635416A (zh) | 2020-12-22 | 2023-08-22 | 诺华股份有限公司 | 用于在细胞培养期间降低分泌的重组表达蛋白质中半胱氨酸残基的氧化水平的方法 |
AU2023262688A1 (en) | 2022-04-25 | 2024-10-24 | Novartis Ag | Crystalline forms of an il-17 inhibitor |
CN119630422A (zh) | 2022-05-16 | 2025-03-14 | 诺华股份有限公司 | 使用白细胞介素-17(il-17)拮抗剂治疗巨细胞动脉炎的方法 |
IL316872A (en) | 2022-05-18 | 2025-01-01 | Novartis Ag | Methods for selective treatment of tendinopathy using interleukin-17 (IL-17) antagonists |
EP4406553A1 (en) * | 2023-01-27 | 2024-07-31 | Fresenius Kabi Deutschland GmbH | Stable secukinumab biopharmaceutical composition |
WO2024156841A1 (en) * | 2023-01-27 | 2024-08-02 | Fresenius Kabi Deutschland Gmbh | Biopharmaceutical composition |
WO2025049345A1 (en) | 2023-08-25 | 2025-03-06 | Proteologix Us Inc. | Anti-il-13 multispecific antibody constructs and uses thereof |
CN117843778B (zh) * | 2023-12-21 | 2024-07-26 | 北京贝来药业有限公司 | 针对白介素家族成员的新型纳米抗体及其产品和应用 |
WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
CN119331085B (zh) * | 2024-10-16 | 2025-03-14 | 中国科学院合肥物质科学研究院 | 沙贝冠状病毒广谱中和抗体及其应用 |
Family Cites Families (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
DE3785186T2 (de) | 1986-09-02 | 1993-07-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US6562333B1 (en) | 1993-06-14 | 2003-05-13 | Schering Corporation | Purified mammalian CTLA-8 antigens and related reagents |
US6274711B1 (en) * | 1993-06-14 | 2001-08-14 | Inserm, Institut National De La Sante Et De La Recherche Medicale | Purified mammalian CTLA-8 antigens and related reagents |
AU696775B2 (en) | 1995-03-23 | 1998-09-17 | Kirin-Amgen, Inc. | IL-17 receptor |
US6074849A (en) * | 1995-07-19 | 2000-06-13 | Genetics Institute, Inc. | Polynucleotides encoding human CTLA-8 related proteins |
WO1997004097A2 (en) * | 1995-07-19 | 1997-02-06 | Genetics Institute, Inc. | Human ctla-8 and uses of ctla-8-related proteins |
EP0862454B1 (en) | 1995-10-27 | 2002-08-28 | Schering Corporation | Ctla-8 in combination with g-csf or with g-csf and il-6, and use of ctla-8 for treating infections |
DE69739375D1 (de) | 1996-11-27 | 2009-06-04 | Immunex Corp | Verfahren zur regulierung der stickstoffmonoxid-erzeugung |
EP1015488B1 (en) | 1997-09-17 | 2009-09-09 | Human Genome Sciences, Inc. | Interleukin-17 receptor-like protein |
US6482923B1 (en) | 1997-09-17 | 2002-11-19 | Human Genome Sciences, Inc. | Interleukin 17-like receptor protein |
US6849719B2 (en) | 1997-09-17 | 2005-02-01 | Human Genome Sciences, Inc. | Antibody to an IL-17 receptor like protein |
DE69833876T2 (de) | 1997-11-10 | 2007-05-24 | Cytimmune Sciences, Inc. | Zusammensetzungen und verfahren für die gezielte abgabe von faktoren |
US6562578B1 (en) * | 1999-01-11 | 2003-05-13 | Schering Corporation | IL-17-like cytokine binding compounds and antibodies |
WO1999032632A1 (en) | 1997-12-19 | 1999-07-01 | Millennium Pharmaceuticals, Inc. | Novel embryo-derived interleukin related factor molecules and uses therefor |
CA2317817A1 (en) | 1998-01-09 | 1999-07-15 | Immunex Corporation | Il-17rh dna and polypeptides |
AU2031399A (en) | 1998-01-09 | 1999-07-26 | Immunex Corporation | Human and murine il-17d, cytokine related to interleukin-17: dna and polypeptides |
AU3291099A (en) | 1998-02-11 | 1999-08-30 | Maxygen, Inc. | Genetic vaccine vector engineering |
JP3577586B2 (ja) | 1998-05-15 | 2004-10-13 | ジェネンテック・インコーポレーテッド | Il−17相同的ポリペプチドとその治療用途 |
ES2300154T3 (es) | 1998-09-17 | 2008-06-01 | Zymogenetics, Inc. | Factor de crecimiento de transformacion beta-9 en mamiferos (ztgfss9). |
WO2000020593A1 (en) | 1998-10-02 | 2000-04-13 | Eli Lilly And Company | Il-17 homolog nucleic acids, polypeptides, vectors, host cells, methods and uses thereof |
JP2000186046A (ja) * | 1998-10-14 | 2000-07-04 | Snow Brand Milk Prod Co Ltd | 慢性関節リウマチ治療剤及び診断方法 |
AU1071200A (en) | 1998-10-19 | 2000-05-08 | Biotech Australia Pty Limited | Systems for oral delivery |
DE29820466U1 (de) | 1998-11-16 | 1999-04-08 | Reutter, Werner, Prof. Dr.med., 14195 Berlin | Rekombinante Glycoproteine und sie enthaltende Arzneimittel |
US6734172B2 (en) | 1998-11-18 | 2004-05-11 | Pacific Northwest Research Institute | Surface receptor antigen vaccines |
AU3207000A (en) | 1999-01-11 | 2000-08-01 | Schering Corporation | Interleukin-17 related mammalian cytokine (il-171). polynucleotides encoding them. uses |
EP1141297B1 (en) | 1999-01-11 | 2009-09-30 | Schering Corporation | Interleukin-17 related mammalian cytokines. polynucleotides encoding them . uses |
ES2173678T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Vacunacion no invasiva a traves de la piel. |
BR0008161A (pt) | 1999-02-12 | 2002-05-28 | Scripps Research Inst | Uso de uma composição terapêutica para tratamento de uma célula tumoral, composição terapêutica, e kit para tratamento de uma célula tumoral |
US6036128A (en) | 1999-05-17 | 2000-03-14 | Common Ground Recycling, Inc. | Tire shredding machine and method of using the same |
EP1053751A1 (en) | 1999-05-17 | 2000-11-22 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Compositions and methods for treating cell proliferation disorders |
AU6677000A (en) | 1999-08-27 | 2001-03-26 | University Health Network | Method for activating cytotoxic t-lymphocytes (ctls) in vivo : composition comprising antibody anti cd40 (or cd40l or cd40 binding protein) and an antigen |
JP2001086046A (ja) * | 1999-09-09 | 2001-03-30 | Nec Corp | カメラ付き携帯電話装置 |
US7220840B2 (en) * | 2000-06-16 | 2007-05-22 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator protein |
CN1279055C (zh) | 2000-06-16 | 2006-10-11 | 人体基因组科学有限公司 | 免疫特异性结合BLyS的抗体 |
WO2002033083A2 (en) | 2000-10-13 | 2002-04-25 | Eli Lilly And Company | Methods of using a human il-17-related polypeptide to treat disease |
AU2002246746B2 (en) | 2000-10-18 | 2007-05-31 | Kirin-Amgen, Inc. | Methods for treating rheumatoid arthritis using il-17 antagonists |
EP2366406A1 (en) | 2001-01-25 | 2011-09-21 | ZymoGenetics, Inc. | Method for treating psoriasis |
ATE374214T1 (de) * | 2001-04-27 | 2007-10-15 | Kirin Brewery | Monoklonaler anti-cd-40-antikörper |
AU2002364954A1 (en) | 2001-11-16 | 2003-07-15 | Human Genome Sciences, Inc. | ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO BLyS |
EP1545578A4 (en) | 2002-08-28 | 2010-07-07 | Immunex Corp | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASES |
EP1633785B1 (en) * | 2003-05-21 | 2012-11-28 | Medarex, Inc. | Human monoclonal antibodies against bacillusanthracis protective antigen |
AU2004292393C1 (en) | 2003-11-21 | 2011-08-04 | Ucb Pharma S.A. | Method for the treatment of multiple sclerosis by inhibiting IL-17 activity |
WO2005108616A1 (en) * | 2004-05-03 | 2005-11-17 | Schering Corporation | Use of il-17 expression to predict skin inflammation; methods of treatment |
GB0417487D0 (en) * | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
HRP20100014T1 (hr) | 2005-09-01 | 2010-02-28 | Schering Corporation | Uporaba il-23 i il-17 antagonista u liječenju autoimune očne upalne bolesti |
-
2004
- 2004-08-05 GB GBGB0417487.6A patent/GB0417487D0/en not_active Ceased
-
2005
- 2005-08-03 PE PE2005000902A patent/PE20060418A1/es active IP Right Grant
- 2005-08-04 EP EP10175150.1A patent/EP2364729B3/en not_active Expired - Lifetime
- 2005-08-04 PL PL10174725T patent/PL2366405T3/pl unknown
- 2005-08-04 HU HUE10174725A patent/HUE025815T2/en unknown
- 2005-08-04 SI SI200531869T patent/SI2364729T1/sl unknown
- 2005-08-04 ES ES15156029.9T patent/ES2677245T3/es not_active Expired - Lifetime
- 2005-08-04 CA CA2573586A patent/CA2573586C/en not_active Expired - Lifetime
- 2005-08-04 AT AT05770286T patent/ATE517924T1/de active
- 2005-08-04 LT LTEP15156029.9T patent/LT2902039T/lt unknown
- 2005-08-04 WO PCT/EP2005/008470 patent/WO2006013107A1/en active Application Filing
- 2005-08-04 CN CN2005800265694A patent/CN101001645B/zh not_active Expired - Lifetime
- 2005-08-04 ES ES10175150.1T patent/ES2487533T7/es active Active
- 2005-08-04 EP EP15156029.9A patent/EP2902039B1/en not_active Expired - Lifetime
- 2005-08-04 AU AU2005268857A patent/AU2005268857C1/en active Active
- 2005-08-04 DK DK10174725.1T patent/DK2366405T3/en active
- 2005-08-04 PL PL15156029T patent/PL2902039T3/pl unknown
- 2005-08-04 TR TR2018/08057T patent/TR201808057T4/tr unknown
- 2005-08-04 PT PT101751501T patent/PT2364729E/pt unknown
- 2005-08-04 PT PT151560299T patent/PT2902039T/pt unknown
- 2005-08-04 SI SI200531965T patent/SI2366405T1/sl unknown
- 2005-08-04 MY MYPI20053629A patent/MY144925A/en unknown
- 2005-08-04 DK DK15156029.9T patent/DK2902039T3/en active
- 2005-08-04 RU RU2007108067A patent/RU2426741C3/ru active
- 2005-08-04 TW TW094126471A patent/TWI359153B/zh active
- 2005-08-04 KR KR1020087006406A patent/KR20080029018A/ko not_active Withdrawn
- 2005-08-04 PL PL05770286T patent/PL1776142T4/pl unknown
- 2005-08-04 PT PT05770286T patent/PT1776142E/pt unknown
- 2005-08-04 BR BR122018075556-3A patent/BR122018075556B1/pt active IP Right Grant
- 2005-08-04 JP JP2007524286A patent/JP4682200B2/ja not_active Expired - Lifetime
- 2005-08-04 PT PT101747251T patent/PT2366405E/pt unknown
- 2005-08-04 EP EP10174725.1A patent/EP2366405B1/en not_active Expired - Lifetime
- 2005-08-04 HU HUE15156029A patent/HUE038187T2/hu unknown
- 2005-08-04 AR ARP050103256A patent/AR050200A1/es active IP Right Grant
- 2005-08-04 BR BR122017009404-1A patent/BR122017009404B1/pt active IP Right Grant
- 2005-08-04 DK DK05770286.2T patent/DK1776142T6/en active
- 2005-08-04 BR BRPI0513078A patent/BRPI0513078C1/pt active IP Right Grant
- 2005-08-04 ES ES10174725.1T patent/ES2536228T3/es not_active Expired - Lifetime
- 2005-08-04 ES ES05770286.2T patent/ES2367440T7/es active Active
- 2005-08-04 SG SG200905203-6A patent/SG155186A1/en unknown
- 2005-08-04 SI SI200531390T patent/SI1776142T1/sl unknown
- 2005-08-04 SI SI200532208T patent/SI2902039T1/en unknown
- 2005-08-04 NZ NZ552658A patent/NZ552658A/en unknown
- 2005-08-04 EP EP05770286.2A patent/EP1776142B9/en not_active Expired - Lifetime
- 2005-08-04 EP EP18166164.6A patent/EP3409288A1/en not_active Withdrawn
- 2005-08-04 US US11/658,344 patent/US7807155B2/en active Active
- 2005-08-04 DK DK10175150.1T patent/DK2364729T6/en active
- 2005-08-04 MX MX2007001338A patent/MX2007001338A/es active IP Right Grant
- 2005-08-04 KR KR1020077002745A patent/KR100852523B1/ko not_active Expired - Lifetime
- 2005-08-04 HR HRP20110758TT patent/HRP20110758T4/hr unknown
- 2005-08-04 PL PL10175150T patent/PL2364729T6/pl unknown
-
2007
- 2007-01-09 ZA ZA200700242A patent/ZA200700242B/xx unknown
- 2007-01-15 IL IL180717A patent/IL180717A/en active Protection Beyond IP Right Term
- 2007-01-25 EC EC2007007198A patent/ECSP077198A/es unknown
- 2007-02-02 TN TNP2007000034A patent/TNSN07034A1/en unknown
- 2007-02-20 NO NO20070985A patent/NO336279B1/no active Protection Beyond IP Right Term
- 2007-02-22 MA MA29710A patent/MA28982B1/fr unknown
-
2010
- 2010-02-18 US US12/707,934 patent/US8119131B2/en not_active Expired - Lifetime
- 2010-04-28 AU AU2010201689A patent/AU2010201689B2/en active Active
-
2011
- 2011-04-06 RU RU2011113153/10A patent/RU2011113153A/ru not_active Application Discontinuation
- 2011-09-27 CY CY20111100936T patent/CY1111963T1/el unknown
-
2012
- 2012-01-13 US US13/349,689 patent/US8617552B2/en not_active Expired - Lifetime
-
2013
- 2013-11-20 US US14/085,074 patent/US20140079719A1/en not_active Abandoned
-
2014
- 2014-08-08 CY CY20141100628T patent/CY1115444T1/el unknown
-
2015
- 2015-01-13 NO NO20150064A patent/NO337286B1/no active Protection Beyond IP Right Term
- 2015-01-13 NO NO20150065A patent/NO337129B1/no unknown
- 2015-02-18 US US14/625,073 patent/US9765140B2/en not_active Expired - Lifetime
- 2015-05-04 HR HRP20150480TT patent/HRP20150480T1/hr unknown
- 2015-05-07 CY CY20151100401T patent/CY1116256T1/el unknown
- 2015-07-03 FR FR15C0048C patent/FR15C0048I2/fr active Active
- 2015-07-07 BE BE2015C041C patent/BE2015C041I2/nl unknown
- 2015-07-09 NL NL300749C patent/NL300749I2/nl unknown
- 2015-07-09 HU HUS1500037C patent/HUS1500037I1/hu unknown
- 2015-07-10 LT LTPA2015029C patent/LTPA2015029I1/lt unknown
- 2015-07-10 CY CY2015030C patent/CY2015030I2/el unknown
- 2015-07-10 LU LU92768C patent/LU92768I2/xx unknown
- 2015-10-26 NO NO2015023C patent/NO2015023I1/no not_active IP Right Cessation
- 2015-12-23 NO NO20151787A patent/NO341384B1/no active Protection Beyond IP Right Term
-
2016
- 2016-08-23 NO NO2016017C patent/NO2016017I1/no unknown
-
2017
- 2017-08-11 US US15/674,970 patent/US10344084B2/en not_active Expired - Lifetime
- 2017-10-24 NO NO20171697A patent/NO348010B1/no unknown
-
2018
- 2018-02-14 NO NO2018007C patent/NO2018007I1/no unknown
- 2018-07-06 HR HRP20181069TT patent/HRP20181069T1/hr unknown
- 2018-07-11 CY CY181100727T patent/CY1120723T1/el unknown
- 2018-10-10 CY CY2018027C patent/CY2018027I1/el unknown
- 2018-10-10 HU HUS1800040C patent/HUS1800040I1/hu unknown
- 2018-10-10 LT LTPA2018515C patent/LTPA2018515I1/lt unknown
- 2018-10-10 LU LU00088C patent/LUC00088I2/en unknown
- 2018-12-10 HK HK18115774.0A patent/HK1256639A1/en unknown
-
2019
- 2019-05-15 US US16/412,543 patent/US20190270804A1/en not_active Abandoned
-
2022
- 2022-06-24 NO NO2022026C patent/NO2022026I1/no unknown
- 2022-07-07 US US17/859,653 patent/US20230235038A1/en not_active Abandoned
-
2024
- 2024-04-26 US US18/647,368 patent/US20250122277A1/en active Pending