PT1031346E - Vacinacao nao invasiva atraves da pele - Google Patents
Vacinacao nao invasiva atraves da peleInfo
- Publication number
- PT1031346E PT1031346E PT99101479T PT99101479T PT1031346E PT 1031346 E PT1031346 E PT 1031346E PT 99101479 T PT99101479 T PT 99101479T PT 99101479 T PT99101479 T PT 99101479T PT 1031346 E PT1031346 E PT 1031346E
- Authority
- PT
- Portugal
- Prior art keywords
- skin
- invasive vaccination
- vaccination
- invasive
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99101479A EP1031346B1 (en) | 1999-01-27 | 1999-01-27 | Noninvasive vaccination through the skin |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1031346E true PT1031346E (pt) | 2002-09-30 |
Family
ID=8237425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99101479T PT1031346E (pt) | 1999-01-27 | 1999-01-27 | Vacinacao nao invasiva atraves da pele |
Country Status (19)
Country | Link |
---|---|
US (1) | US7867480B1 (pt) |
EP (2) | EP1031346B1 (pt) |
JP (1) | JP2002535350A (pt) |
KR (2) | KR20010112252A (pt) |
CN (1) | CN1230151C (pt) |
AR (1) | AR037312A1 (pt) |
AT (1) | ATE216875T1 (pt) |
AU (1) | AU778972B2 (pt) |
BR (1) | BR0007749A (pt) |
CA (1) | CA2360692C (pt) |
DE (1) | DE69901377T2 (pt) |
DK (1) | DK1031346T3 (pt) |
ES (1) | ES2173678T3 (pt) |
HK (1) | HK1030363A1 (pt) |
HU (1) | HU225170B1 (pt) |
MX (1) | MXPA01007657A (pt) |
PT (1) | PT1031346E (pt) |
SI (1) | SI1031346T1 (pt) |
WO (1) | WO2000044349A1 (pt) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
US7030212B1 (en) | 1998-07-31 | 2006-04-18 | Haruo Sugiyama | Tumor antigen based on products of the tumor suppressor gene WT1 |
DK1031347T3 (da) | 1999-01-27 | 2002-07-08 | Idea Ag | Transnasal transport/immunisering med meget tilpasselige bærere |
ES2173678T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Vacunacion no invasiva a traves de la piel. |
FR2822049B1 (fr) | 2001-03-13 | 2003-08-01 | Dbv Medica 1 | Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation |
US7635488B2 (en) | 2001-03-13 | 2009-12-22 | Dbv Technologies | Patches and uses thereof |
TWI318630B (en) | 2001-03-22 | 2009-12-21 | Int Inst Cancer Immunology Inc | Wt1 modified peptide |
US20020193729A1 (en) | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
WO2003028758A1 (fr) * | 2001-09-28 | 2003-04-10 | Haruo Sugiyama | Nouvelle methode d'induction de lymphocytes t specifiques d'un antigene |
JP5230891B2 (ja) * | 2001-09-28 | 2013-07-10 | 株式会社癌免疫研究所 | 抗原特異的t細胞の新規な誘導方法 |
JP2006503072A (ja) * | 2002-10-02 | 2006-01-26 | ノルディック ワクチン テクノロジー アクティーゼルスカブ | ワクチン接種用組成物 |
GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
JP4703724B2 (ja) | 2006-04-28 | 2011-06-15 | ゼルティック エステティックス インコーポレイテッド | 皮下の脂質リッチ細胞の冷却が改善された治療装置に使用する凍結防止剤 |
US9132031B2 (en) | 2006-09-26 | 2015-09-15 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US20080077201A1 (en) | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
US8192474B2 (en) | 2006-09-26 | 2012-06-05 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
US20080287839A1 (en) | 2007-05-18 | 2008-11-20 | Juniper Medical, Inc. | Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator |
US8523927B2 (en) | 2007-07-13 | 2013-09-03 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
US8285390B2 (en) | 2007-08-21 | 2012-10-09 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
FR2924349B1 (fr) * | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
FR2924350B1 (fr) | 2007-12-03 | 2010-08-13 | Dbv Tech | Procede et compositions pour la vaccination par voie cutanee |
US8603073B2 (en) | 2008-12-17 | 2013-12-10 | Zeltiq Aesthetics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
BRPI1014623B1 (pt) | 2009-04-30 | 2020-01-07 | Zeltiq Aesthetics, Inc. | Sistema para tratamento de celulas subcutâneas ricas em lipídeos em uma área alvo |
WO2011000889A1 (en) * | 2009-06-30 | 2011-01-06 | William Henry | Topical vaccine formulations and methods of treating drug addiction using same |
JP2013502436A (ja) | 2009-08-21 | 2013-01-24 | ターゲッティド デリバリー テクノロジーズ リミテッド | 小胞状の製剤 |
AU2011207506A1 (en) | 2010-01-25 | 2012-08-09 | Zeltiq Aesthetics, Inc. | Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods |
US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
GB201212010D0 (en) * | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
US8652457B2 (en) | 2012-07-13 | 2014-02-18 | Wisconsin Alumni Research Foundation | Interleukin-10 peptides and antibodies thereof for inhibiting adverse effects of protozoan infection |
US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
ES2542088B1 (es) * | 2014-01-29 | 2016-05-05 | Enoc Solutions, S.L. | Composición de azufre liposomado |
ES2974899T3 (es) | 2014-01-31 | 2024-07-02 | Zeltiq Aesthetics Inc | Composiciones y sistemas de tratamiento para el enfriamiento mejorado de tejido rico en lípidos |
US10675176B1 (en) | 2014-03-19 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Treatment systems, devices, and methods for cooling targeted tissue |
USD777338S1 (en) | 2014-03-20 | 2017-01-24 | Zeltiq Aesthetics, Inc. | Cryotherapy applicator for cooling tissue |
US10952891B1 (en) | 2014-05-13 | 2021-03-23 | Zeltiq Aesthetics, Inc. | Treatment systems with adjustable gap applicators and methods for cooling tissue |
US9821028B2 (en) * | 2014-07-11 | 2017-11-21 | Wisconsin Alumni Research Foundation | Methods of controlling parasitic worms in animals |
US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
US10935174B2 (en) | 2014-08-19 | 2021-03-02 | Zeltiq Aesthetics, Inc. | Stress relief couplings for cryotherapy apparatuses |
WO2017001617A1 (en) | 2015-06-30 | 2017-01-05 | Sequessome Technology Holdings Limited | Blended formulations |
WO2017070112A1 (en) | 2015-10-19 | 2017-04-27 | Zeltiq Aesthetics, Inc. | Vascular treatment systems, cooling devices, and methods for cooling vascular structures |
US10524956B2 (en) | 2016-01-07 | 2020-01-07 | Zeltiq Aesthetics, Inc. | Temperature-dependent adhesion between applicator and skin during cooling of tissue |
US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
MX2019002835A (es) | 2016-09-13 | 2019-09-04 | Allergan Inc | Composiciones no proteínicas de toxina clostridial. |
US11076879B2 (en) | 2017-04-26 | 2021-08-03 | Zeltiq Aesthetics, Inc. | Shallow surface cryotherapy applicators and related technology |
BR112020004869A2 (pt) | 2017-09-12 | 2020-09-15 | Wisconsin Alumni Research Foundation | peptídeo do receptor-2 de interleucina-10, anticorpos, composições, e métodos de uso dos mesmos |
EP3829496A1 (en) | 2018-07-31 | 2021-06-09 | Zeltiq Aesthetics, Inc. | Methods, devices, and systems for improving skin characteristics |
CN114075551B (zh) * | 2021-06-11 | 2024-01-26 | 华中农业大学 | 沙林鼠种布鲁氏菌脂多糖的单克隆抗体及应用 |
Family Cites Families (127)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2160326B1 (pt) | 1971-11-19 | 1975-02-07 | Anvar | |
US4185100A (en) | 1976-05-13 | 1980-01-22 | Johnson & Johnson | Topical anti-inflammatory drug therapy |
US4095596A (en) | 1976-11-26 | 1978-06-20 | Smithkline Corporation | Nasal inhaler |
US4369182A (en) | 1978-09-27 | 1983-01-18 | A. Nattermann & Cie Gmbh | Inflammation-preventing pharmaceutical composition of oral administration |
JPS55153713A (en) | 1979-05-02 | 1980-11-29 | Kureha Chem Ind Co Ltd | Pharmaceutical preparation of ribosome containing active substance |
US4383993A (en) | 1980-05-30 | 1983-05-17 | University Of Kentucky Research Foundation | Nasal dosage forms containing natural female sex hormones |
IL64397A0 (en) | 1981-01-07 | 1982-02-28 | Weder Hans G | Process for the preparation of liposomal medicaments |
EP0088046B1 (de) | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
EP0102324A3 (de) | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipide und Tenside in wässriger Phase |
USRE33273E (en) | 1982-08-18 | 1990-07-24 | Georgia Tech Research Corporation | Materials having improved nonfouling characteristics and method of making same |
FR2542998B1 (fr) | 1983-03-24 | 1986-01-31 | Rhone Poulenc Sante | Nouvelle forme transdermale du dinitrate d'isosorbide |
GB8321913D0 (en) | 1983-08-15 | 1983-09-14 | Acacia Chem Ltd | Spray method |
EP0152379A3 (de) | 1984-02-15 | 1986-10-29 | Ciba-Geigy Ag | Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen |
US5008050A (en) | 1984-06-20 | 1991-04-16 | The Liposome Company, Inc. | Extrusion technique for producing unilamellar vesicles |
US4897269A (en) | 1984-09-24 | 1990-01-30 | Mezei Associates Limited | Administration of drugs with multiphase liposomal delivery system |
US4921706A (en) | 1984-11-20 | 1990-05-01 | Massachusetts Institute Of Technology | Unilamellar lipid vesicles and method for their formation |
IL79114A (en) | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
JPS6295134A (ja) | 1985-10-21 | 1987-05-01 | Nippon Saafuakutanto Kogyo Kk | リポソ−ムの製造法 |
IN166447B (pt) | 1985-11-27 | 1990-05-12 | Ethicon Inc | |
DE3542773A1 (de) | 1985-12-04 | 1987-06-11 | Roehm Pharma Gmbh | Hautwirksame pharmaka mit liposomen als wirkstofftraeger |
US5244678A (en) | 1986-01-14 | 1993-09-14 | Ire-Celltarg S.A. | Pharmaceutical composition containing a local anesthetic and/or centrally acting analgesic encapsulated in liposomes |
FR2597367B1 (fr) | 1986-04-22 | 1988-07-15 | Oreal | Procede pour faciliter la formation de spherules lipidiques en dispersion dans une phase aqueuse et pour ameliorer leur stabilite et leur taux d'encapsulation, et dispersions correspondantes. |
EP0293465B1 (en) | 1986-11-28 | 1992-03-18 | The Liposome Company, Inc. | Phospholipid composition |
US4938970A (en) | 1987-02-06 | 1990-07-03 | Hustead Robert E | Painless electrolyte solutions |
DK86988A (da) | 1987-02-25 | 1988-08-26 | Takeda Chemical Industries Ltd | Liposompraeparat og anvendelse deraf |
US5154930A (en) | 1987-03-05 | 1992-10-13 | The Liposome Company, Inc. | Pharmacological agent-lipid solution preparation |
CA1323306C (en) | 1987-03-05 | 1993-10-19 | Mircea C. Popescu | Pharmacological agent-lipid solution preparation |
US4855090A (en) | 1987-03-13 | 1989-08-08 | Micro-Pak, Inc. | Method of producing high aqueous volume multilamellar vesicles |
US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
US4783450A (en) | 1987-04-13 | 1988-11-08 | Warner-Lambert Company | Use of commercial lecithin as skin penetration enhancer |
US5238613A (en) | 1987-05-20 | 1993-08-24 | Anderson David M | Microporous materials |
IL86650A0 (en) | 1987-06-30 | 1988-11-30 | Biophor Corp | Animal derived cells and liposomes,having an antigenic protein incorporated into their membrane |
US4849224A (en) | 1987-11-12 | 1989-07-18 | Theratech Inc. | Device for administering an active agent to the skin or mucosa |
US4983395A (en) | 1987-11-12 | 1991-01-08 | Theratech Inc. | Device for administering an active agent to the skin or mucosa |
US4937078A (en) | 1988-08-26 | 1990-06-26 | Mezei Associates Limited | Liposomal local anesthetic and analgesic products |
US5043165A (en) | 1988-12-14 | 1991-08-27 | Liposome Technology, Inc. | Novel liposome composition for sustained release of steroidal drugs |
US5049392A (en) | 1989-01-18 | 1991-09-17 | The Liposome Company, Inc. | Osmotically dependent vesicles |
US4944948A (en) | 1989-02-24 | 1990-07-31 | Liposome Technology, Inc. | EGF/Liposome gel composition and method |
EP0393707B1 (en) | 1989-04-21 | 1994-10-26 | Otsuka Pharmaceutical Co., Ltd. | Bioactive compounds associated with liposomes and their use in pharmaceutical preparations |
WO1991001146A1 (en) * | 1989-07-14 | 1991-02-07 | Praxis Biologics, Inc. | Cytokine and hormone carriers for conjugate vaccines |
AU629671B2 (en) | 1989-08-03 | 1992-10-08 | Hisamitsu Pharmaceutical Co. Inc. | Skin cream preparation for external use |
US5104661A (en) | 1989-08-14 | 1992-04-14 | Technology Unlimited, Inc. | Reverse loading of liposomes |
US5209720A (en) | 1989-12-22 | 1993-05-11 | Unger Evan C | Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes |
US6165500A (en) | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
WO1992003122A1 (de) | 1990-08-24 | 1992-03-05 | Gregor Cevc | Präparat zur wirkstoffapplikation in kleinsttröpfchenform |
EP0548210A1 (en) * | 1990-09-10 | 1993-06-30 | School Of Pharmacy, University Of London | Liposomes |
US5202125A (en) | 1990-12-10 | 1993-04-13 | Theratech, Inc. | Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes |
US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
US5552160A (en) | 1991-01-25 | 1996-09-03 | Nanosystems L.L.C. | Surface modified NSAID nanoparticles |
JP2922017B2 (ja) | 1991-03-25 | 1999-07-19 | 第一製薬株式会社 | 経口用脂質膜構造体 |
US5498420A (en) | 1991-04-12 | 1996-03-12 | Merz & Co. Gmbh & Co. | Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions |
HU223343B1 (hu) | 1991-05-20 | 2004-06-28 | Novartis Ag. | Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására |
ES2077419T3 (es) | 1991-06-10 | 1995-11-16 | Sanol Arznei Schwarz Gmbh | Emplasto con nitroglicerol y procedimiento para su produccion. |
IT1250691B (it) | 1991-07-22 | 1995-04-21 | Giancarlo Santus | Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac. |
GB9116610D0 (en) | 1991-08-01 | 1991-09-18 | Danbiosyst Uk | Preparation of microparticles |
EG20380A (en) | 1991-10-16 | 1999-02-28 | Richardson Vicks Inc | Enhanced skin penetration system for improved topical delivery of drugs |
HUT74560A (en) | 1991-10-16 | 1997-01-28 | Richardson Vicks Inc | Enhanced skin penetration system for improved topical delivery of drugs |
US5985860A (en) | 1992-06-03 | 1999-11-16 | Toppo; Frank | System for transdermal delivery of pain relieving substances |
CA2141192C (en) | 1992-07-28 | 1999-02-02 | Roberta C. Bloom | Pharmaceutical composition for topical use containing a crosslinked cationic polymer and an alkoxylated ether |
ES2136105T3 (es) | 1992-08-04 | 1999-11-16 | Rhone Poulenc Rorer Gmbh | Preparacion farmaceutica y/o cosmetica. |
ATE192327T1 (de) | 1993-03-24 | 2000-05-15 | Collaborative Lab Inc | Kosmetisches verabreichungssystem für salizylsäure und verfahren zur herstellung desselben |
DE4336557C2 (de) | 1993-05-06 | 1997-07-17 | Lohmann Therapie Syst Lts | Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung |
US5460820B1 (en) | 1993-08-03 | 1999-08-03 | Theratech Inc | Method for providing testosterone and optionally estrogen replacement therapy to women |
FR2714601B1 (fr) | 1993-12-30 | 1996-02-09 | Oreal | Composition dépigmentante pour le traitement simultané des couches superficielles et profondes, son utilisation. |
US5716526A (en) | 1994-01-14 | 1998-02-10 | The Liposome Company, Inc. | Method of separating materials from liposomes or lipid complexes |
US5536263A (en) | 1994-03-30 | 1996-07-16 | Lectec Corporation | Non-occulusive adhesive patch for applying medication to the skin |
US5540934A (en) | 1994-06-22 | 1996-07-30 | Touitou; Elka | Compositions for applying active substances to or through the skin |
ATE223202T1 (de) | 1994-09-30 | 2002-09-15 | Mika Pharma Ges Fuer Die Entwi | Pharmazeutische zusammensetzung |
IT1270678B (it) | 1994-10-20 | 1997-05-07 | Bayer Ag | Liposomi al chetoprofen |
US20020048596A1 (en) | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
DE4447287C1 (de) | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
US5763422A (en) | 1995-01-27 | 1998-06-09 | Board Of Regents, The University Of Texas System | Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein |
US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
IT1275955B1 (it) | 1995-03-22 | 1997-10-24 | Dompe Spa | Formulazioni farmaceutiche in forma di gel tissotropico |
US5654337A (en) | 1995-03-24 | 1997-08-05 | II William Scott Snyder | Topical formulation for local delivery of a pharmaceutically active agent |
DE19512181C2 (de) | 1995-03-31 | 2003-11-06 | Hexal Pharma Gmbh | Transdermales System mit Ramipril und/oder Trandolapril als ACE-Hemmer |
DE19518221A1 (de) | 1995-05-10 | 1996-11-14 | Schering Ag | Verwendung nichtsteroidaler Entzündungshemmer zur Verbesserung der physiologischen Verträglichkeit partikulärer pharmazeutischer Zubereitungen |
US5653987A (en) | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
US5908839A (en) | 1995-08-24 | 1999-06-01 | Magainin Pharmaceuticals, Inc. | Asthma associated factors as targets for treating atopic allergies including asthma and related disorders |
US6214386B1 (en) | 1995-11-22 | 2001-04-10 | Recordati, S.A. | Prompt-release oral pharmaceutical compositions for extemporaneous suspensions |
US5783208A (en) | 1996-07-19 | 1998-07-21 | Theratech, Inc. | Transdermal drug delivery matrix for coadministering estradiol and another steroid |
US5837289A (en) | 1996-07-23 | 1998-11-17 | Grasela; John C. | Transdermal delivery of medications using a combination of penetration enhancers |
US6797276B1 (en) | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
US5980898A (en) * | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
US5891472A (en) | 1996-11-19 | 1999-04-06 | Meri Charmyne Russell | Treatment of equine laminitis |
US6090800A (en) | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
WO1998050071A1 (en) * | 1997-05-01 | 1998-11-12 | Chiron Corporation | Use of virus-like particles as adjuvants |
US6274634B1 (en) | 1997-05-14 | 2001-08-14 | Senju Pharmaceutical Co., Ltd. | Aqueous suspension preparations with excellent redispersibility |
JP2002506448A (ja) * | 1997-06-24 | 2002-02-26 | カイロン コーポレイション | 抗髄膜炎菌ワクチン組成物を使用して成体を免疫する方法 |
US6083996A (en) | 1997-11-05 | 2000-07-04 | Nexmed Holdings, Inc. | Topical compositions for NSAI drug delivery |
IT1298214B1 (it) | 1998-01-28 | 1999-12-20 | Dompe Spa | Sali dell'acido (r) 2-(3-benzoilfenil) propionico e loro composizioni farmaceutiche. |
US6193996B1 (en) | 1998-04-02 | 2001-02-27 | 3M Innovative Properties Company | Device for the transdermal delivery of diclofenac |
US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
US6200598B1 (en) | 1998-06-18 | 2001-03-13 | Duke University | Temperature-sensitive liposomal formulation |
US6726925B1 (en) | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
SE9802864D0 (sv) | 1998-08-27 | 1998-08-27 | Pharmacia & Upjohn Ab | Transdermally administered tolterodine as antimuscarinic agent for the treatment of overactive bladder |
EP1143958B8 (en) | 1998-09-03 | 2007-05-23 | Loma Linda University Medical Center | Pharmaceutical composition and use of rnsaid for treating inflammation |
CN1192766C (zh) | 1998-10-23 | 2005-03-16 | 伊迪亚股份公司 | 开发、测试和使用用于改进的有效负载和可控制性解缔/缔合速度的大分子和复合聚集体的缔合物的方法 |
ES2226203T3 (es) | 1998-12-23 | 2005-03-16 | Idea Ag | Formulacion mejorada para aplicacion topica no invasiva. |
DK1031347T3 (da) | 1999-01-27 | 2002-07-08 | Idea Ag | Transnasal transport/immunisering med meget tilpasselige bærere |
ES2173678T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Vacunacion no invasiva a traves de la piel. |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
US6362227B1 (en) | 1999-03-02 | 2002-03-26 | Sepracor, Inc. | Methods for the treatment of tinnitus and other disorders using R(−)ketoptofen |
US7063859B1 (en) | 1999-04-28 | 2006-06-20 | Noven Pharmaceuticals, Inc. | Barrier film lined backing layer composition and method for topical administration of active agents |
US6726598B1 (en) | 1999-06-18 | 2004-04-27 | Powerlung, Inc. | Pulmonary exercise device |
WO2001001962A1 (en) | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
US6276598B1 (en) | 1999-07-13 | 2001-08-21 | Asm Assembly Automation Ltd. | Method and apparatus for ball placement |
JP2001036949A (ja) | 1999-07-19 | 2001-02-09 | Hitachi Ltd | 無線通信方法および無線通信システム |
US6685928B2 (en) | 1999-12-07 | 2004-02-03 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
US6248353B1 (en) | 1999-12-10 | 2001-06-19 | Dade Behring Inc. | Reconstitution of purified membrane proteins into preformed liposomes |
US6645520B2 (en) | 1999-12-16 | 2003-11-11 | Dermatrends, Inc. | Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers |
US6562370B2 (en) | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers |
US6586000B2 (en) | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
US6582724B2 (en) | 1999-12-16 | 2003-06-24 | Dermatrends, Inc. | Dual enhancer composition for topical and transdermal drug delivery |
US6673363B2 (en) | 1999-12-16 | 2004-01-06 | Dermatrends, Inc. | Transdermal and topical administration of local anesthetic agents using basic enhancers |
EP1116485A3 (de) | 2000-01-10 | 2002-01-16 | Gerhard Dr. Gergely | Instant-Granulat und Verfahren zu seiner Herstellung |
US20020119188A1 (en) | 2000-02-08 | 2002-08-29 | Susan Niemiec | Method of manufacturing liposomes |
DE60133270T2 (de) | 2000-05-10 | 2009-04-23 | Jagotec Ag | Zerkleinerung mittels mahlkörper |
CA2412376A1 (en) | 2000-07-26 | 2002-01-31 | Onkar N. Singh | Pharmaceutical suspension compositions lacking a polymeric suspending agent |
US6387383B1 (en) | 2000-08-03 | 2002-05-14 | Dow Pharmaceutical Sciences | Topical low-viscosity gel composition |
KR20030079784A (ko) | 2002-04-04 | 2003-10-10 | 마츠시타 덴끼 산교 가부시키가이샤 | 냉동 사이클 장치와, 그것을 구비하는 공기 조화기,냉장고, 온수 공급기 및 극저온 냉동 장치 |
US7473432B2 (en) | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
EP1551370B1 (en) | 2002-10-11 | 2007-12-19 | Idea Ag | Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
US7387788B1 (en) | 2003-10-10 | 2008-06-17 | Antares Pharma Ipl Ag | Pharmaceutical compositions of nicotine and methods of use thereof |
WO2005063213A1 (en) | 2003-12-19 | 2005-07-14 | Biodelivery Sciences International, Inc. | Rigid liposomal cochleate and methods of use and manufacture |
GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
CA2584475A1 (en) | 2004-11-12 | 2006-05-18 | Idea Ag | Extended surface aggregates in the treatment of skin conditions |
-
1999
- 1999-01-27 ES ES99101479T patent/ES2173678T3/es not_active Expired - Lifetime
- 1999-01-27 EP EP99101479A patent/EP1031346B1/en not_active Expired - Lifetime
- 1999-01-27 PT PT99101479T patent/PT1031346E/pt unknown
- 1999-01-27 DK DK99101479T patent/DK1031346T3/da active
- 1999-01-27 DE DE69901377T patent/DE69901377T2/de not_active Expired - Lifetime
- 1999-01-27 SI SI9930060T patent/SI1031346T1/xx unknown
- 1999-01-27 AT AT99101479T patent/ATE216875T1/de active
-
2000
- 2000-01-26 US US09/890,335 patent/US7867480B1/en not_active Expired - Fee Related
- 2000-01-26 HU HU0200315A patent/HU225170B1/hu not_active IP Right Cessation
- 2000-01-26 WO PCT/EP2000/000597 patent/WO2000044349A1/en active IP Right Grant
- 2000-01-26 MX MXPA01007657A patent/MXPA01007657A/es not_active IP Right Cessation
- 2000-01-26 BR BR0007749-6A patent/BR0007749A/pt not_active Application Discontinuation
- 2000-01-26 CN CNB008044538A patent/CN1230151C/zh not_active Expired - Fee Related
- 2000-01-26 KR KR1020017009479A patent/KR20010112252A/ko not_active Application Discontinuation
- 2000-01-26 AU AU27988/00A patent/AU778972B2/en not_active Ceased
- 2000-01-26 EP EP00906231A patent/EP1146858A1/en not_active Withdrawn
- 2000-01-26 KR KR1020077018740A patent/KR20070094662A/ko not_active Application Discontinuation
- 2000-01-26 JP JP2000595653A patent/JP2002535350A/ja active Pending
- 2000-01-26 CA CA2360692A patent/CA2360692C/en not_active Expired - Fee Related
- 2000-01-27 AR ARP000100372A patent/AR037312A1/es unknown
-
2001
- 2001-02-16 HK HK01101136A patent/HK1030363A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SI1031346T1 (en) | 2002-08-31 |
ATE216875T1 (de) | 2002-05-15 |
HK1030363A1 (en) | 2003-05-06 |
HU225170B1 (en) | 2006-07-28 |
US7867480B1 (en) | 2011-01-11 |
AU778972B2 (en) | 2004-12-23 |
EP1031346A1 (en) | 2000-08-30 |
DE69901377T2 (de) | 2003-01-02 |
AR037312A1 (es) | 2004-11-03 |
KR20010112252A (ko) | 2001-12-20 |
CA2360692A1 (en) | 2000-08-03 |
CN1230151C (zh) | 2005-12-07 |
EP1146858A1 (en) | 2001-10-24 |
AU2798800A (en) | 2000-08-18 |
DE69901377D1 (de) | 2002-06-06 |
ES2173678T3 (es) | 2002-10-16 |
DK1031346T3 (da) | 2002-08-12 |
EP1031346B1 (en) | 2002-05-02 |
HUP0200315A2 (en) | 2002-05-29 |
CA2360692C (en) | 2011-01-04 |
KR20070094662A (ko) | 2007-09-20 |
WO2000044349A1 (en) | 2000-08-03 |
MXPA01007657A (es) | 2003-06-24 |
BR0007749A (pt) | 2001-11-13 |
JP2002535350A (ja) | 2002-10-22 |
CN1342066A (zh) | 2002-03-27 |
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