BE2014C053I2 - - Google Patents

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Publication number
BE2014C053I2
BE2014C053I2 BE2014C053C BE2014C053C BE2014C053I2 BE 2014C053 I2 BE2014C053 I2 BE 2014C053I2 BE 2014C053 C BE2014C053 C BE 2014C053C BE 2014C053 C BE2014C053 C BE 2014C053C BE 2014C053 I2 BE2014C053 I2 BE 2014C053I2
Authority
BE
Belgium
Application number
BE2014C053C
Other languages
French (fr)
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BE2014C053I2 publication Critical patent/BE2014C053I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BE2014C053C 2002-10-11 2014-09-09 BE2014C053I2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002298259 2002-10-11
PCT/JP2003/013070 WO2004033463A1 (ja) 2002-10-11 2003-10-10 ２，３−ジヒドロ−６−ニトロイミダゾ[２，１−ｂ]オキサゾール化合物

Publications (1)

Publication Number Publication Date
BE2014C053I2 true BE2014C053I2 (pt) 2022-08-30

Family

ID=32089299

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2014C053C BE2014C053I2 (pt) 2002-10-11 2014-09-09

Country Status (27)

Country Link
US (1) US7262212B2 (pt)
EP (2) EP2570418A3 (pt)
JP (1) JP4186065B2 (pt)
KR (1) KR100723847B1 (pt)
CN (4) CN100366624C (pt)
AR (4) AR041198A1 (pt)
AU (1) AU2003272979B2 (pt)
BE (1) BE2014C053I2 (pt)
BR (1) BRPI0314344B8 (pt)
CA (1) CA2497569C (pt)
CY (2) CY1113578T1 (pt)
DK (1) DK1555267T3 (pt)
ES (1) ES2400179T3 (pt)
FR (1) FR14C0066I2 (pt)
HK (2) HK1085463A1 (pt)
HU (1) HUS1400046I1 (pt)
LU (1) LU92517I2 (pt)
MX (1) MXPA05003674A (pt)
MY (1) MY139244A (pt)
PL (3) PL409525A1 (pt)
PT (1) PT1555267E (pt)
RU (1) RU2326121C3 (pt)
SI (1) SI1555267T1 (pt)
TW (1) TWI347946B (pt)
UA (1) UA83200C2 (pt)
WO (1) WO2004033463A1 (pt)
ZA (1) ZA200501033B (pt)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
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AU2003301282B2 (en) * 2002-10-15 2009-04-30 Otsuka Pharmaceutical Co., Ltd. 1-substituted 4-nitroimidazole compound and process for producing the same
AU2004285811B2 (en) * 2003-10-31 2008-06-12 Otsuka Pharmaceutical Co., Ltd. 2,3-dihydro-6-nitroimidazo (2,1-B) oxazole compounds for the treatment of tuberculosis
JP4761756B2 (ja) * 2003-10-31 2011-08-31 大塚製薬株式会社 ２，３−ジヒドロイミダゾ［２，１−ｂ］オキサゾ−ル化合物
TWI300409B (en) 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound
WO2005095380A1 (ja) 2004-03-31 2005-10-13 Nippon Soda Co., Ltd. 環状アミン化合物および有害生物防除剤
JP4789966B2 (ja) * 2004-04-09 2011-10-12 大塚製薬株式会社 医薬組成物
JP4787529B2 (ja) * 2004-04-09 2011-10-05 大塚製薬株式会社 医薬組成物
US7408066B2 (en) * 2005-06-20 2008-08-05 Schering Corproation Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists
SI1906926T1 (sl) * 2005-07-28 2011-02-28 Otsuka Pharma Co Ltd Farmacevtski sestavek, ki obsega 2,3-dihidro-6-nitroimidazo(2,1-b)oksazolne derivate
JP5105818B2 (ja) * 2005-10-05 2012-12-26 大塚製薬株式会社 医薬組成物
TW201233389A (en) * 2005-10-05 2012-08-16 Otsuka Pharma Co Ltd Antituberculous therapeutic drugs and kit containing the same
US7999102B2 (en) 2005-10-06 2011-08-16 Nippon Soda Co., Ltd. Cross-linked cyclic amine compounds and agents for pest control
TW200800268A (en) * 2005-11-04 2008-01-01 Otsuka Pharma Co Ltd Medicinal composition showing improved drug absorbability
US7750012B2 (en) 2005-12-21 2010-07-06 Decode Genetics Ehf Biaryl nitrogen-heterocycle inhibitors of LTA4H for treating inflammation
JP2009526773A (ja) * 2006-02-13 2009-07-23 ラボラトワール セローノ ソシエテ アノニム 細菌感染症治療のためのスルホンアミド誘導体
JP2007297305A (ja) * 2006-04-28 2007-11-15 Daiso Co Ltd Ｎ−（２，３−エポキシ−２−メチルプロピル）フタルイミドの製造法
CA2678577A1 (en) * 2007-02-26 2008-09-04 Vitae Pharmaceuticals, Inc. Cyclic urea and carbamate inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
AR070301A1 (es) 2007-05-08 2010-03-31 Otsuka Pharma Co Ltd Compuesto epoxi y metodo para producir el mismo
JP5451611B2 (ja) * 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター
PE20090595A1 (es) * 2007-08-15 2009-06-06 Glaxo Group Ltd Derivados de quinoliniloxipiperidina y pirrolidina como antagonistas del receptor h1
JP2011500634A (ja) * 2007-10-16 2011-01-06 グラクソ グループ リミテッド 炎症性疾患およびアレルギー性疾患の治療に用いるキノリン誘導体
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
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CA2712500A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
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JP5730021B2 (ja) * 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
JP5538356B2 (ja) * 2008-03-18 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤
AU2009228293B2 (en) * 2008-03-26 2012-11-08 Tennor Therapeutics (Suzhou) Limited Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
JP5451752B2 (ja) * 2008-05-01 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
EP2291371B1 (en) 2008-05-01 2015-06-10 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
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US9540322B2 (en) 2008-08-18 2017-01-10 Yale University MIF modulators
BRPI0917394A2 (pt) * 2008-08-18 2019-09-24 Univ Yale moduladores de mif
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TWI687409B (zh) 2014-08-28 2020-03-11 日商大塚製藥股份有限公司 稠合雜環化合物
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CN105732659B (zh) * 2014-12-12 2019-07-16 上海阳帆医药科技有限公司 硝基咪唑类化合物及其制备方法和在制药中的用途
JP6542900B2 (ja) * 2015-01-29 2019-07-10 メッドシャイン ディスカバリー インコーポレイテッド 抗肺結核症のニトロイミダゾール誘導体
JP6776226B2 (ja) * 2015-03-27 2020-10-28 大塚製薬株式会社 １−（４−ヒドロキシフェニル）−４−（４−トリフルオロメトキシフェノキシ）ピペリジン又はその塩の製造方法
CN106317072B (zh) * 2015-06-17 2020-03-17 盟科医药技术(上海)有限公司 用于分枝杆菌感染治疗的杂环化合物及其应用
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CN105859628B (zh) * 2016-04-19 2018-08-07 清远职业技术学院 一种抗菌化合物对n咪唑苯甲醛缩邻甲苯胺希夫碱及其制备方法和应用
EP3489242A4 (en) * 2016-07-22 2020-06-24 Medshine Discovery Inc. NITROIMIDAZOLE CRYSTAL AND SALT, AND THEIR MANUFACTURING METHOD
CN110997680B (zh) * 2017-08-16 2022-10-21 葛兰素史密斯克莱知识产权发展有限公司 新型化合物
KR20210019056A (ko) 2018-06-11 2021-02-19 오츠카 세이야쿠 가부시키가이샤 델라마니드 함유 조성물
CN109705022A (zh) * 2018-12-28 2019-05-03 上海彩迩文生化科技有限公司 一种芳香胺中间体的制备方法
CN112300192B (zh) * 2019-08-02 2023-08-11 南京长澳医药科技有限公司 硝基咪唑类化合物及其制备方法和用途
CN110483549B (zh) * 2019-08-30 2021-03-05 沈阳药科大学 一种硝基咪唑吡喃类抗结核药物的制备方法
CN110615800A (zh) * 2019-10-16 2019-12-27 李丽丽 硝基咪唑类化合物及其制备方法和用途
CN112156088B (zh) * 2020-10-30 2021-08-31 健民药业集团股份有限公司 一种化合物在制备结核分枝杆菌抑制剂中的用途
CN113603706A (zh) * 2021-08-04 2021-11-05 深圳市泰力生物医药有限公司 德拉马尼的晶型、含有该晶型的活性药物和药物组合物
CN115368252B (zh) * 2022-09-19 2024-01-12 西北农林科技大学 一种4-胺基酚类衍生物及应用
CN116640106B (zh) * 2023-05-11 2024-03-08 郑州大学 一种苯基哌嗪类化合物及其制备方法、应用

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Publication number Priority date Publication date Assignee Title
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Also Published As

Publication number Publication date
CY2014041I2 (el) 2016-07-27
KR100723847B1 (ko) 2007-05-31
CY2014041I1 (el) 2016-07-27
CA2497569C (en) 2011-05-24
CY1113578T1 (el) 2016-06-22
BRPI0314344B8 (pt) 2021-05-25
US20060094767A1 (en) 2006-05-04
ZA200501033B (en) 2006-06-28
EP1555267B1 (en) 2013-01-16
PL409525A1 (pl) 2014-11-10
UA83200C2 (en) 2008-06-25
BRPI0314344B1 (pt) 2019-11-26
AR041198A1 (es) 2005-05-04
HK1085463A1 (en) 2006-08-25
MXPA05003674A (es) 2005-06-08
CN102532162A (zh) 2012-07-04
WO2004033463A1 (ja) 2004-04-22
PL217919B1 (pl) 2014-09-30
AU2003272979A1 (en) 2004-05-04
FR14C0066I2 (fr) 2015-05-22
US7262212B2 (en) 2007-08-28
BR0314344A (pt) 2005-07-12
EP2570418A3 (en) 2013-07-03
CN100366624C (zh) 2008-02-06
PT1555267E (pt) 2013-01-29
LU92517I2 (fr) 2014-10-13
TWI347946B (en) 2011-09-01
EP1555267A1 (en) 2005-07-20
HUS1400046I1 (hu) 2017-04-28
FR14C0066I1 (pt) 2014-10-17
RU2005114017A (ru) 2006-01-20
CN1705670A (zh) 2005-12-07
CA2497569A1 (en) 2004-04-22
PL404913A1 (pl) 2013-09-30
RU2326121C3 (ru) 2021-09-17
DK1555267T3 (da) 2013-02-11
AU2003272979B2 (en) 2009-07-23
AR091771A2 (es) 2015-02-25
TW200420568A (en) 2004-10-16
EP2570418A2 (en) 2013-03-20
PL376157A1 (en) 2005-12-27
RU2326121C2 (ru) 2008-06-10
CN102532162B (zh) 2015-05-27
CN101255170A (zh) 2008-09-03
MY139244A (en) 2009-09-30
JP4186065B2 (ja) 2008-11-26
AR086485A2 (es) 2013-12-18
HK1171018A1 (en) 2013-03-15
EP1555267A4 (en) 2010-08-18
AR089950A2 (es) 2014-10-01
SI1555267T1 (sl) 2013-05-31
ES2400179T3 (es) 2013-04-08
CN101172981A (zh) 2008-05-07
JP2004149527A (ja) 2004-05-27
KR20050061473A (ko) 2005-06-22

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