BE1005579A5 - Procede pour la production de glycosyltransferases, vecteur hybride et souches de levures utilises a cette fin. - Google Patents

Procede pour la production de glycosyltransferases, vecteur hybride et souches de levures utilises a cette fin. Download PDF

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Publication number
BE1005579A5
BE1005579A5 BE9200491A BE9200491A BE1005579A5 BE 1005579 A5 BE1005579 A5 BE 1005579A5 BE 9200491 A BE9200491 A BE 9200491A BE 9200491 A BE9200491 A BE 9200491A BE 1005579 A5 BE1005579 A5 BE 1005579A5
Authority
BE
Belgium
Prior art keywords
leu
promoter
sequence
dna
yeast
Prior art date
Application number
BE9200491A
Other languages
English (en)
French (fr)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9208211A external-priority patent/GB2256197B/en
Application filed by Ciba Geigy filed Critical Ciba Geigy
Application granted granted Critical
Publication of BE1005579A5 publication Critical patent/BE1005579A5/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BE9200491A 1991-05-31 1992-05-27 Procede pour la production de glycosyltransferases, vecteur hybride et souches de levures utilises a cette fin. BE1005579A5 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP91810414 1991-05-31
EP92810167 1992-03-04
GB9208211A GB2256197B (en) 1991-05-31 1992-04-14 Yeast as host for expression of heterologous glycosyl transferase enzymes

Publications (1)

Publication Number Publication Date
BE1005579A5 true BE1005579A5 (fr) 1993-11-09

Family

ID=27234292

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9200491A BE1005579A5 (fr) 1991-05-31 1992-05-27 Procede pour la production de glycosyltransferases, vecteur hybride et souches de levures utilises a cette fin.

Country Status (19)

Country Link
JP (1) JPH05199871A (xx)
AT (1) AT401940B (xx)
AU (1) AU655470B2 (xx)
BE (1) BE1005579A5 (xx)
CA (1) CA2070057A1 (xx)
DK (1) DK71992A (xx)
ES (1) ES2046118B1 (xx)
FI (1) FI922515A (xx)
GR (1) GR920100250A (xx)
HU (1) HU212927B (xx)
IE (1) IE69059B1 (xx)
IL (1) IL102052A0 (xx)
IT (1) IT1255044B (xx)
LU (1) LU88123A1 (xx)
MX (1) MX9202583A (xx)
NO (1) NO922134L (xx)
NZ (1) NZ242958A (xx)
PT (1) PT100545A (xx)
SE (1) SE9201544L (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7819584U1 (de) * 1978-06-30 1978-10-12 Howmedica International, Inc. Zweigniederlassung Kiel, 2301 Schoenkirchen Tubenartiger vorratsbehaelter fuer medizinisches spritzgeraet
HU219260B (en) * 1992-03-09 2001-03-28 Cytel Corp Recombinant polypeptid with sialyltransferase activity, dna molecule coding thereof and vectors
AU4858801A (en) * 2000-04-13 2001-10-30 Biotica Tech Ltd Hybrid glycosylated products and their production and use
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
EP2338333B1 (en) 2003-04-09 2017-09-06 ratiopharm GmbH Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
WO2006010143A2 (en) 2004-07-13 2006-01-26 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
SI2586456T1 (sl) 2004-10-29 2016-05-31 Ratiopharm Gmbh Preoblikovanje in glikopegliacija fibroblastnega rastnega faktorja (FGF)
EP1858543B1 (en) 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylated granulocyte colony stimulating factor
WO2006121569A2 (en) 2005-04-08 2006-11-16 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
CN101516388B (zh) 2006-07-21 2012-10-31 诺和诺德公司 通过o-联糖基化序列的肽的糖基化
EP2054521A4 (en) 2006-10-03 2012-12-19 Novo Nordisk As METHODS OF PURIFYING CONJUGATES OF POLYPEPTIDES
ES2406267T3 (es) 2007-04-03 2013-06-06 Biogenerix Ag Métodos de tratamiento usando G-CSF glicopegilado
WO2008154639A2 (en) 2007-06-12 2008-12-18 Neose Technologies, Inc. Improved process for the production of nucleotide sugars
PL2257311T3 (pl) 2008-02-27 2014-09-30 Novo Nordisk As Koniugaty cząsteczek czynnika VIII

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0288435A1 (en) * 1987-04-15 1988-10-26 Ciba-Geigy Ag Process for the production of proteins
WO1991006635A1 (en) * 1989-10-24 1991-05-16 Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
WO1991012340A1 (en) * 1990-02-14 1991-08-22 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
WO1991016900A1 (en) * 1990-04-27 1991-11-14 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990007000A2 (en) * 1988-12-13 1990-06-28 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0288435A1 (en) * 1987-04-15 1988-10-26 Ciba-Geigy Ag Process for the production of proteins
WO1991006635A1 (en) * 1989-10-24 1991-05-16 Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
WO1991012340A1 (en) * 1990-02-14 1991-08-22 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
WO1991016900A1 (en) * 1990-04-27 1991-11-14 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIOCHEM. BIOPHYS. RES. COMMUN. vol. 157, no. 2, 15 Décembre 1988, ACADEMIC PRESS, N.Y., US; pages 657 - 663 K.A. MASRI ET AL. 'Identification of the full-length coding sequence for human galactosyltransferase (beta-N-acetylglucosaminide: beta-1,4-galactosyltransferase)' the whole document *
J. BIOL. CHEM. vol. 262, no. 36, 25 Décembre 1987, AM. SOC. MOL. BIOL., INC. US; pages 17735 - 17743 J. WEINSTEIN ET AL. 'Primary structure of Beta-galactoside-alpha2,6-sialyltransferas e' the whole document *
J. BIOL. CHEM. vol. 263, no. 21, 25 Juillet 1988, AM. SOC. MOL. BIOL. INC., US; pages 10420 - 10428 N.L. SHAPER ET AL. 'Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase' the whole document *
J. BIOL. CHEM. vol. 264, no. 24, 25 Août 1989, AM. SOC. MOL. BIOL. INC., US; pages 14290 - 14297 D.H. JOZIASSE ET AL. 'Bovine alpha-1,3-galactosyltransferase: Isolation and characterization of a cDNA' the whole document *
NUCL. ACIDS RES. vol. 18, no. 23, 11 Décembre 1990, IRL PRESS, OXFORD, UK; page 7174 G. WATZELE AND E.G. BERGER 'Near identity of HeLa cell galactosyltransferase with the human placental enzyme' the whole document *

Also Published As

Publication number Publication date
LU88123A1 (de) 1993-12-06
ES2046118B1 (es) 1994-08-16
NO922134L (no) 1992-12-01
GR920100250A (el) 1993-03-31
ES2046118A1 (es) 1994-01-16
AT401940B (de) 1996-12-27
ITRM920411A0 (it) 1992-05-29
ITRM920411A1 (it) 1993-11-29
SE9201544L (sv) 1992-12-01
HU212927B (en) 1996-12-30
FI922515A (fi) 1992-12-01
PT100545A (pt) 1993-08-31
IT1255044B (it) 1995-10-17
CA2070057A1 (en) 1992-12-01
NO922134D0 (no) 1992-05-29
ATA112792A (de) 1996-05-15
HUT65728A (en) 1994-07-28
FI922515A0 (fi) 1992-05-29
NZ242958A (en) 1993-06-25
MX9202583A (es) 1992-11-01
DK71992D0 (da) 1992-05-29
IL102052A0 (en) 1992-12-30
IE921769A1 (en) 1992-12-02
DK71992A (da) 1992-12-01
HU9201787D0 (en) 1992-08-28
SE9201544D0 (sv) 1992-05-15
AU655470B2 (en) 1994-12-22
AU1705292A (en) 1992-12-03
JPH05199871A (ja) 1993-08-10
IE69059B1 (en) 1996-08-07

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RE Patent lapsed

Owner name: NOVARTIS A.G.

Effective date: 19990531