GR920100250A - Βελτιωμένη μέ?οδος για την παραγωγή γλυκοσυλοτρανσφεράσης. - Google Patents

Βελτιωμένη μέ?οδος για την παραγωγή γλυκοσυλοτρανσφεράσης.

Info

Publication number
GR920100250A
GR920100250A GR920100250A GR920100250A GR920100250A GR 920100250 A GR920100250 A GR 920100250A GR 920100250 A GR920100250 A GR 920100250A GR 920100250 A GR920100250 A GR 920100250A GR 920100250 A GR920100250 A GR 920100250A
Authority
GR
Greece
Prior art keywords
production
glycosyltransferases
improved process
glucosyltransferases
interconnected
Prior art date
Application number
GR920100250A
Other languages
English (en)
Inventor
Eric Dr Prof Berger
Bernd Dr Meyhack
Gabriele Dr Watzele
Manfred Dr Watzele
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9208211A external-priority patent/GB2256197B/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of GR920100250A publication Critical patent/GR920100250A/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

H εφεύρεση σχετίζεται με το πεδίο της τεχνολογίας του ανασυνδεόμενου DNA και περιέχει μια νέα μέθοδο γι ατην παραγωγή γλυκοσυλοτρανφερασών με χρήση μετασχηματισμένων στελεχών ζύμης. ω
GR920100250A 1991-05-31 1992-05-29 Βελτιωμένη μέ?οδος για την παραγωγή γλυκοσυλοτρανσφεράσης. GR920100250A (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP91810414 1991-05-31
EP92810167 1992-03-04
GB9208211A GB2256197B (en) 1991-05-31 1992-04-14 Yeast as host for expression of heterologous glycosyl transferase enzymes

Publications (1)

Publication Number Publication Date
GR920100250A true GR920100250A (el) 1993-03-31

Family

ID=27234292

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920100250A GR920100250A (el) 1991-05-31 1992-05-29 Βελτιωμένη μέ?οδος για την παραγωγή γλυκοσυλοτρανσφεράσης.

Country Status (19)

Country Link
JP (1) JPH05199871A (el)
AT (1) AT401940B (el)
AU (1) AU655470B2 (el)
BE (1) BE1005579A5 (el)
CA (1) CA2070057A1 (el)
DK (1) DK71992A (el)
ES (1) ES2046118B1 (el)
FI (1) FI922515A (el)
GR (1) GR920100250A (el)
HU (1) HU212927B (el)
IE (1) IE69059B1 (el)
IL (1) IL102052A0 (el)
IT (1) IT1255044B (el)
LU (1) LU88123A1 (el)
MX (1) MX9202583A (el)
NO (1) NO922134L (el)
NZ (1) NZ242958A (el)
PT (1) PT100545A (el)
SE (1) SE9201544L (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7819584U1 (de) * 1978-06-30 1978-10-12 Howmedica International, Inc. Zweigniederlassung Kiel, 2301 Schoenkirchen Tubenartiger vorratsbehaelter fuer medizinisches spritzgeraet
SK108894A3 (en) * 1992-03-09 1995-07-11 Univ California Sialyltransferases and isolated dna fraction coding sialyltransferases
WO2001079520A1 (en) * 2000-04-13 2001-10-25 Biotica Technology Limited Hybrid glycosylated products and their production and use
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
EP1814573B1 (en) 2004-10-29 2016-03-09 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
CA2593682C (en) 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
JP2009544327A (ja) 2006-07-21 2009-12-17 ノヴォ ノルディスク アー／エス Ｏ−結合型グリコシル化配列によるペプチドのグリコシル化
EP2054521A4 (en) 2006-10-03 2012-12-19 Novo Nordisk As METHODS OF PURIFYING CONJUGATES OF POLYPEPTIDES
KR20150064246A (ko) 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
ES2551123T3 (es) 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
CN101965200B (zh) 2008-02-27 2013-06-19 诺沃-诺迪斯克有限公司 缀合的因子ⅷ分子

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0288435A1 (en) * 1987-04-15 1988-10-26 Ciba-Geigy Ag Process for the production of proteins
WO1991006635A1 (en) * 1989-10-24 1991-05-16 Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
WO1991012340A1 (en) * 1990-02-14 1991-08-22 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
WO1991016900A1 (en) * 1990-04-27 1991-11-14 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4751990A (en) * 1988-12-13 1990-07-10 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0288435A1 (en) * 1987-04-15 1988-10-26 Ciba-Geigy Ag Process for the production of proteins
WO1991006635A1 (en) * 1989-10-24 1991-05-16 Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
WO1991012340A1 (en) * 1990-02-14 1991-08-22 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules
WO1991016900A1 (en) * 1990-04-27 1991-11-14 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIOCHEM. BIOPHYS. RES. COMMUN. vol. 157, no. 2, 15 December 1988, ACADEMIC PRESS, N.Y., US; pages 657 - 663 K.A. MASRI ET AL. 'Identification of the full-length coding sequence for human galactosyltransferase (beta-N-acetylglucosaminide: beta-1,4-galactosyltransferase)' the whole document *
J. BIOL. CHEM. vol. 262, no. 36, 25 December 1987, AM. SOC. MOL. BIOL., INC. US; pages 17735 - 17743 J. WEINSTEIN ET AL. 'Primary structure of Beta-galactoside-alpha2,6-sialyltransferas e' the whole document *
J. BIOL. CHEM. vol. 263, no. 21, 25 July 1988, AM. SOC. MOL. BIOL. INC., US; pages 10420 - 10428 N.L. SHAPER ET AL. 'Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase' the whole document *
J. BIOL. CHEM. vol. 264, no. 24, 25 August 1989, AM. SOC. MOL. BIOL. INC., US; pages 14290 - 14297 D.H. JOZIASSE ET AL. 'Bovine alpha-1,3-galactosyltransferase: Isolation and characterization of a cDNA' the whole document *
NUCL. ACIDS RES. vol. 18, no. 23, 11 December 1990, IRL PRESS, OXFORD, UK; page 7174 G. WATZELE AND E.G. BERGER 'Near identity of HeLa cell galactosyltransferase with the human placental enzyme' the whole document *

Also Published As

Publication number Publication date
FI922515A0 (fi) 1992-05-29
NZ242958A (en) 1993-06-25
CA2070057A1 (en) 1992-12-01
HUT65728A (en) 1994-07-28
DK71992D0 (da) 1992-05-29
AU655470B2 (en) 1994-12-22
ITRM920411A1 (it) 1993-11-29
ATA112792A (de) 1996-05-15
IT1255044B (it) 1995-10-17
JPH05199871A (ja) 1993-08-10
HU9201787D0 (en) 1992-08-28
IL102052A0 (en) 1992-12-30
ES2046118A1 (es) 1994-01-16
DK71992A (da) 1992-12-01
ES2046118B1 (es) 1994-08-16
NO922134D0 (no) 1992-05-29
BE1005579A5 (fr) 1993-11-09
IE69059B1 (en) 1996-08-07
PT100545A (pt) 1993-08-31
SE9201544L (sv) 1992-12-01
LU88123A1 (de) 1993-12-06
AT401940B (de) 1996-12-27
SE9201544D0 (sv) 1992-05-15
ITRM920411A0 (it) 1992-05-29
HU212927B (en) 1996-12-30
IE921769A1 (en) 1992-12-02
NO922134L (no) 1992-12-01
AU1705292A (en) 1992-12-03
MX9202583A (es) 1992-11-01
FI922515A (fi) 1992-12-01

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