IT1255044B - Procedimento per produrre glicosiltransferasi, vettore ibrido di lievito in esso impiegato e ceppo di lievito trasformato con impiego di vettore ibrido - Google Patents

Procedimento per produrre glicosiltransferasi, vettore ibrido di lievito in esso impiegato e ceppo di lievito trasformato con impiego di vettore ibrido

Info

Publication number
IT1255044B
IT1255044B ITRM920411A ITRM920411A IT1255044B IT 1255044 B IT1255044 B IT 1255044B IT RM920411 A ITRM920411 A IT RM920411A IT RM920411 A ITRM920411 A IT RM920411A IT 1255044 B IT1255044 B IT 1255044B
Authority
IT
Italy
Prior art keywords
hybrid
employed
procedure
glycosyltransferase
yeast stock
Prior art date
Application number
ITRM920411A
Other languages
English (en)
Inventor
Gabriele Watzele
Eric Berger
Bernd Meyhack
Manfred Watzele
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9208211A external-priority patent/GB2256197B/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ITRM920411A0 publication Critical patent/ITRM920411A0/it
Publication of ITRM920411A1 publication Critical patent/ITRM920411A1/it
Application granted granted Critical
Publication of IT1255044B publication Critical patent/IT1255044B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La invenzione si riferisce al campo della tecnologia di DNA ricombinante e fornisce un nuovo metodo per la produzione di glicosiltransferasi mediante impiego di ceppi di lievito trasformati.
ITRM920411A 1991-05-31 1992-05-29 Procedimento per produrre glicosiltransferasi, vettore ibrido di lievito in esso impiegato e ceppo di lievito trasformato con impiego di vettore ibrido IT1255044B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP91810414 1991-05-31
EP92810167 1992-03-04
GB9208211A GB2256197B (en) 1991-05-31 1992-04-14 Yeast as host for expression of heterologous glycosyl transferase enzymes

Publications (3)

Publication Number Publication Date
ITRM920411A0 ITRM920411A0 (it) 1992-05-29
ITRM920411A1 ITRM920411A1 (it) 1993-11-29
IT1255044B true IT1255044B (it) 1995-10-17

Family

ID=27234292

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920411A IT1255044B (it) 1991-05-31 1992-05-29 Procedimento per produrre glicosiltransferasi, vettore ibrido di lievito in esso impiegato e ceppo di lievito trasformato con impiego di vettore ibrido

Country Status (19)

Country Link
JP (1) JPH05199871A (it)
AT (1) AT401940B (it)
AU (1) AU655470B2 (it)
BE (1) BE1005579A5 (it)
CA (1) CA2070057A1 (it)
DK (1) DK71992A (it)
ES (1) ES2046118B1 (it)
FI (1) FI922515A (it)
GR (1) GR920100250A (it)
HU (1) HU212927B (it)
IE (1) IE69059B1 (it)
IL (1) IL102052A0 (it)
IT (1) IT1255044B (it)
LU (1) LU88123A1 (it)
MX (1) MX9202583A (it)
NO (1) NO922134L (it)
NZ (1) NZ242958A (it)
PT (1) PT100545A (it)
SE (1) SE9201544L (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7819584U1 (de) * 1978-06-30 1978-10-12 Howmedica International, Inc. Zweigniederlassung Kiel, 2301 Schoenkirchen Tubenartiger vorratsbehaelter fuer medizinisches spritzgeraet
NZ251096A (en) * 1992-03-09 1996-03-26 Univ California Sialyltransferases and compositions and methods for their identification and synthesis
DK1278881T3 (da) * 2000-04-13 2010-05-10 Biotica Tech Ltd Glycosylerede hybrid-produkter og deres fremstilling og anvendelse
AU2004236174B2 (en) 2001-10-10 2011-06-02 Novo Nordisk A/S Glycopegylation methods and proteins/peptides produced by the methods
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
DK2586456T3 (en) 2004-10-29 2016-03-21 Ratiopharm Gmbh Conversion and glycopegylation of fibroblast growth factor (FGF)
EP1858543B1 (en) 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylated granulocyte colony stimulating factor
EP2386571B1 (en) 2005-04-08 2016-06-01 ratiopharm GmbH Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
EP2049144B8 (en) 2006-07-21 2015-02-18 ratiopharm GmbH Glycosylation of peptides via o-linked glycosylation sequences
US20100075375A1 (en) 2006-10-03 2010-03-25 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
CN101796063B (zh) 2007-04-03 2017-03-22 拉蒂奥法姆有限责任公司 使用糖聚乙二醇化g‑csf的治疗方法
ES2551123T3 (es) 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
MX2010009154A (es) 2008-02-27 2010-09-09 Novo Nordisk As Moleculas conjugadas del factor viii.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY103358A (en) * 1987-04-15 1993-06-30 Novartis Ag Process for the production of protiens.
WO1990007000A2 (en) * 1988-12-13 1990-06-28 La Jolla Cancer Research Foundation Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
DE69131925D1 (de) * 1990-02-14 2000-02-24 Univ Michigan Ann Arbor Verfahren und produkte für die synthese von oligosaccharidstrukturen auf glykoproteinen, glykolipiden oder als freie moleküle
WO1991016900A1 (en) * 1990-04-27 1991-11-14 Biogen, Inc. Fucosyl transferases involved in adhesion molecule expression
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen

Also Published As

Publication number Publication date
HU212927B (en) 1996-12-30
CA2070057A1 (en) 1992-12-01
ITRM920411A1 (it) 1993-11-29
HU9201787D0 (en) 1992-08-28
FI922515A0 (fi) 1992-05-29
IE921769A1 (en) 1992-12-02
BE1005579A5 (fr) 1993-11-09
NO922134D0 (no) 1992-05-29
NZ242958A (en) 1993-06-25
FI922515A (fi) 1992-12-01
IL102052A0 (en) 1992-12-30
ATA112792A (de) 1996-05-15
PT100545A (pt) 1993-08-31
SE9201544L (sv) 1992-12-01
ITRM920411A0 (it) 1992-05-29
DK71992D0 (da) 1992-05-29
DK71992A (da) 1992-12-01
ES2046118B1 (es) 1994-08-16
AU655470B2 (en) 1994-12-22
MX9202583A (es) 1992-11-01
JPH05199871A (ja) 1993-08-10
LU88123A1 (de) 1993-12-06
IE69059B1 (en) 1996-08-07
HUT65728A (en) 1994-07-28
NO922134L (no) 1992-12-01
GR920100250A (el) 1993-03-31
ES2046118A1 (es) 1994-01-16
SE9201544D0 (sv) 1992-05-15
AU1705292A (en) 1992-12-03
AT401940B (de) 1996-12-27

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970407