BE1003093A3 - Procede de preparation d'une composition pharmaceutique sous forme de microparticules. - Google Patents

Procede de preparation d'une composition pharmaceutique sous forme de microparticules. Download PDF

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Publication number
BE1003093A3
BE1003093A3 BE9000729A BE9000729A BE1003093A3 BE 1003093 A3 BE1003093 A3 BE 1003093A3 BE 9000729 A BE9000729 A BE 9000729A BE 9000729 A BE9000729 A BE 9000729A BE 1003093 A3 BE1003093 A3 BE 1003093A3
Authority
BE
Belgium
Prior art keywords
preparation
microparticles
pharmaceutical composition
extrusion
composition
Prior art date
Application number
BE9000729A
Other languages
English (en)
French (fr)
Inventor
Piero Orsolini
Original Assignee
Debio Rech Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debio Rech Pharma Sa filed Critical Debio Rech Pharma Sa
Application granted granted Critical
Publication of BE1003093A3 publication Critical patent/BE1003093A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
BE9000729A 1989-07-28 1990-07-18 Procede de preparation d'une composition pharmaceutique sous forme de microparticules. BE1003093A3 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2829/89A CH679207A5 (show.php) 1989-07-28 1989-07-28

Publications (1)

Publication Number Publication Date
BE1003093A3 true BE1003093A3 (fr) 1991-11-19

Family

ID=4242536

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9000729A BE1003093A3 (fr) 1989-07-28 1990-07-18 Procede de preparation d'une composition pharmaceutique sous forme de microparticules.

Country Status (23)

Country Link
US (1) US5134122A (show.php)
JP (1) JPH0662427B2 (show.php)
AT (1) AT397197B (show.php)
AU (1) AU619996B2 (show.php)
BE (1) BE1003093A3 (show.php)
CA (1) CA2021767C (show.php)
CH (1) CH679207A5 (show.php)
DE (1) DE4023134C2 (show.php)
DK (1) DK175495B1 (show.php)
ES (1) ES2020890A6 (show.php)
FI (1) FI97688C (show.php)
FR (1) FR2650182B1 (show.php)
GB (1) GB2234169B (show.php)
GR (1) GR1001215B (show.php)
IE (1) IE65397B1 (show.php)
IL (1) IL95120A (show.php)
IT (1) IT1243357B (show.php)
LU (1) LU87772A1 (show.php)
NL (1) NL194858C (show.php)
NO (1) NO300304B1 (show.php)
PT (1) PT94842B (show.php)
SE (1) SE504279C2 (show.php)
ZA (1) ZA905654B (show.php)

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WO1993015722A1 (en) * 1992-02-07 1993-08-19 Syntex (Usa) Inc. Controlled delivery of pharmaceuticals from preformed porous microparticles
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
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JPS60181029A (ja) * 1984-02-29 1985-09-14 Toyo Jozo Co Ltd 徐放性製剤の製法
FR2620621A1 (fr) * 1987-09-21 1989-03-24 Bpd Biopharm Dev Ltd Composition pharmaceutique pour la liberation soutenue et controlee de polypeptides insolubles dans l'eau

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Also Published As

Publication number Publication date
AT397197B (de) 1994-02-25
SE504279C2 (sv) 1996-12-23
FR2650182B1 (fr) 1992-05-15
FI903643A0 (fi) 1990-07-19
SE9002522D0 (sv) 1990-07-27
SE9002522L (sv) 1991-01-29
IT9021019A1 (it) 1992-01-23
ATA154590A (de) 1993-07-15
DK175495B1 (da) 2004-11-08
NL9001646A (nl) 1991-02-18
LU87772A1 (fr) 1990-12-11
NO903264D0 (no) 1990-07-23
ZA905654B (en) 1991-05-29
DK180790A (da) 1991-01-29
IL95120A (en) 1994-10-07
IL95120A0 (en) 1991-06-10
FI97688C (fi) 1997-02-10
IE902592A1 (en) 1991-02-27
GR900100568A (en) 1991-12-10
AU619996B2 (en) 1992-02-06
DK180790D0 (da) 1990-07-27
DE4023134C2 (de) 1997-04-17
NL194858C (nl) 2003-05-06
CH679207A5 (show.php) 1992-01-15
FI97688B (fi) 1996-10-31
NL194858B (nl) 2003-01-06
PT94842A (pt) 1991-03-20
CA2021767C (en) 1996-10-22
IT9021019A0 (it) 1990-07-23
NO300304B1 (no) 1997-05-12
NO903264L (no) 1991-01-29
PT94842B (pt) 1997-04-30
ES2020890A6 (es) 1991-10-01
GB9015722D0 (en) 1990-09-05
IE65397B1 (en) 1995-10-18
US5134122A (en) 1992-07-28
GB2234169A (en) 1991-01-30
CA2021767A1 (en) 1991-01-29
JPH0366625A (ja) 1991-03-22
JPH0662427B2 (ja) 1994-08-17
GB2234169B (en) 1993-02-10
AU5910390A (en) 1991-01-31
IT1243357B (it) 1994-06-10
FR2650182A1 (fr) 1991-02-01
DE4023134A1 (de) 1991-01-31
GR1001215B (el) 1993-06-21

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