BA98301A - Postupak za dobijanje antiaritmickih agenasa - Google Patents

Postupak za dobijanje antiaritmickih agenasa

Info

Publication number
BA98301A
BA98301A BA980301A BA980301A BA98301A BA 98301 A BA98301 A BA 98301A BA 980301 A BA980301 A BA 980301A BA 980301 A BA980301 A BA 980301A BA 98301 A BA98301 A BA 98301A
Authority
BA
Bosnia and Herzegovina
Prior art keywords
alkyl
group
formula
compounds
antiarrhythmic agents
Prior art date
Application number
BA980301A
Other languages
Bosnian (bs)
English (en)
Inventor
Geoffrey Noel Thomas
Peter Edward Cross
John Edmund Arrowsmith
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26290703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BA98301(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB868610668A external-priority patent/GB8610668D0/en
Priority claimed from GB868630059A external-priority patent/GB8630059D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of BA98301A publication Critical patent/BA98301A/bs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Polyamides (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Lubricants (AREA)
  • Plural Heterocyclic Compounds (AREA)
BA980301A 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa BA98301A (bs)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB868610668A GB8610668D0 (en) 1986-05-01 1986-05-01 Anti-arrhythmia agents
GB868630059A GB8630059D0 (en) 1986-12-17 1986-12-17 Antiarrhythmic agents
YU73588A YU46541B (sh) 1986-05-01 1988-04-12 Postupak za dobijanje antiaritmičkih agenasa
BA980211A BA98211B1 (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa

Publications (1)

Publication Number Publication Date
BA98301A true BA98301A (bs) 2001-09-14

Family

ID=26290703

Family Applications (2)

Application Number Title Priority Date Filing Date
BA980211A BA98211B1 (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa
BA980301A BA98301A (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BA980211A BA98211B1 (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa

Country Status (27)

Country Link
US (2) US4959366A (fr)
EP (1) EP0245997B1 (fr)
KR (2) KR870011084A (fr)
CN (1) CN1019801B (fr)
AT (1) ATE74906T1 (fr)
AU (1) AU578557B2 (fr)
BA (2) BA98211B1 (fr)
CA (1) CA1289140C (fr)
DE (2) DE3778201D1 (fr)
DK (1) DK175096B1 (fr)
EG (1) EG18188A (fr)
ES (1) ES2033840T3 (fr)
FI (1) FI88291C (fr)
GR (1) GR3004457T3 (fr)
HU (1) HU196743B (fr)
IE (1) IE59366B1 (fr)
IL (1) IL82373A (fr)
LU (1) LU90519I2 (fr)
LV (1) LV5715B4 (fr)
MY (1) MY111142A (fr)
NL (1) NL300002I2 (fr)
NO (2) NO168527C (fr)
NZ (1) NZ220151A (fr)
PH (1) PH23425A (fr)
PL (1) PL149924B1 (fr)
PT (1) PT84782B (fr)
YU (2) YU46195B (fr)

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US5602174A (en) * 1986-02-15 1997-02-11 Beecham Wuefling Gmbh & Co. Treatment
NL8700842A (fr) * 1987-04-10 1988-11-01 Duphar Int Res
SE8705150D0 (sv) * 1987-12-23 1987-12-23 Haessle Ab Novel antiarrhythmic agents
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
GB8819307D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Antiarrhythmic agents
US5086073A (en) * 1989-06-02 1992-02-04 John Wyeth & Brother Limited Composition for treating depression with aralkyl amines
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5084463A (en) * 1989-12-11 1992-01-28 American Home Products Corporation N-quinolinyl alkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing class III antiarrhythmic activity
AU4787593A (en) * 1992-07-31 1994-03-03 Syntex (U.S.A.) Inc. Heterocyclic derivatives useful in the treatment of cardiovascular diseases
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
GB9404485D0 (en) * 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
DE4422517A1 (de) * 1994-06-28 1996-01-04 Dresden Arzneimittel Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JP3904599B2 (ja) * 1994-08-04 2007-04-11 シー・アンド・シー・リサーチ・ラブズ 新規なアミン誘導体、その製造方法及び抗不整脈剤としての用途
DE69500377T2 (de) 1994-08-19 1997-10-09 Mitsui Toatsu Chemicals Pyrimidin-Dion-Derivate und diese enthaltende antiarrhythmische Zusammensetzungen
US5679706A (en) * 1994-09-30 1997-10-21 Bristol-Myers Squibb Company Combination of a potassium channel activator and an antiarrhythmic agent
FR2726267B1 (fr) * 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
CN1055682C (zh) * 1995-12-06 2000-08-23 中国药科大学 甲磺酰胺基苯乙胺衍生物的新制备方法
CN1055679C (zh) * 1995-12-06 2000-08-23 中国药科大学 具有心血管活性的苯乙胺衍生物
GB9722662D0 (en) * 1997-10-27 1997-12-24 Pfizer Ltd Polymorphs
HUP9702411A2 (hu) * 1997-12-11 2000-03-28 Gyógyszerkutató Intézet Kft. Fenoxi-alkil-amin-származékok és a vegyületeket tartalmazó antiaritmiás hatású gyógyszerkészítmények
EP1436258A4 (fr) * 2001-03-08 2005-03-23 Univ Emory Antagonistes du recepteur nmda dependant du ph
CN100358865C (zh) * 2001-07-30 2008-01-02 中国科学院上海药物研究所 一类磺酰胺苯烷胺类化合物及其制备方法和用途
DE10201550A1 (de) * 2002-01-17 2003-07-31 Merck Patent Gmbh Phenoxy-Piperidine
AU2002357560A1 (en) * 2002-04-26 2003-11-10 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Sulfamidophenylalkylamines and their production and use
EA016558B1 (ru) * 2003-06-17 2012-05-30 Арена Фармасьютикалз, Инк. Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором
MXPA05013364A (es) * 2003-06-17 2006-03-17 Arena Pharm Inc Procedimiento para preparar 3-benzazepinas.
DE102004025726B4 (de) * 2004-05-26 2006-07-06 Roder, Hanno, Dr. Verwendung eines spezifischen K252a-Derivats zur Verhinderung oder Behandlung der Alzheimerschen Krankheit
CA2672650C (fr) * 2006-12-14 2015-09-08 Tautatis, Inc. Compositions et procedes pour le traitement du cancer
EP2170334B1 (fr) * 2007-06-29 2021-03-17 Emory University Antagonistes des récepteurs nmda pour la neuroprotection
CN101372467B (zh) * 2007-08-23 2011-09-14 明德国际仓储贸易(上海)有限公司 具有n,n-二烷氨基的桥基化合物及所应用的染料化合物
WO2009111004A1 (fr) 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Procédés de préparation d'intermédiaires se rapportant à l'agoniste 5-ht<sb>2c</sb> (r)-8-chloro-1-méthyl-2,3,4,5-tétrahydro-1h-3-benzazepine
WO2010148207A2 (fr) 2009-06-18 2010-12-23 Arena Pharmaceuticals, Inc. Procédés pour la préparation d'agonistes du récepteur 5-ht2c
US9045431B2 (en) 2010-06-02 2015-06-02 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
WO2012030939A1 (fr) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Administration de lorcasérine à des individus présentant une insuffisance rénale
MX2013002421A (es) 2010-09-01 2013-05-17 Arena Pharm Inc Sales no hidroscopicas de agonistas de 5-ht2c.
WO2012030938A1 (fr) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Sels de lorcasérine dotés d'acides optiquement actifs
CN102531946A (zh) * 2012-01-05 2012-07-04 山东大学 3-甲氧基苯甲酰胺衍生物及其制备方法与应用
AU2012392187B2 (en) 2012-10-09 2018-07-12 Arena Pharmaceuticals, Inc. Method of weight management
FR3029113A1 (fr) 2014-12-02 2016-06-03 Univ Paris-Sud Composes pour le traitement des maladies mitochondriales
CZ2017772A3 (cs) * 2017-12-01 2019-05-29 Farmak, A.S. Způsob přípravy N-[4-(2-{[2-(4-methansulfonamidofenoxy)ethyl](methyl)amino}ethyl)fenyl]methansulfonamidu (Dofetilidu)
US10888524B2 (en) 2018-02-05 2021-01-12 Enaltec Pharma Research Pvt. Ltd. Immediate release tablet of dofetilide

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Publication number Priority date Publication date Assignee Title
FR977261A (fr) * 1948-11-04 1951-03-29 équilibrage des masses dans les moteurs à combustion interne
FR148F (fr) * 1962-01-24
US3478149A (en) * 1962-01-24 1969-11-11 Mead Johnson & Co Therapeutic compositions and methods employing sulfonamidophenethanolamines
US3852468A (en) * 1967-02-27 1974-12-03 Ici Ltd Alkanolamine derivatives as {62 -adrenergic blocking agents
US3758692A (en) * 1969-04-14 1973-09-11 Mead Johnson & Co Ylamines sympathomimetic process and compositions employing sulfonamidophenalk
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
GB1263987A (en) * 1969-05-30 1972-02-16 Allen & Hanburys Ltd Phenethylamine derivatives
BE757005A (fr) * 1969-10-02 1971-04-02 Bristol Myers Co Phenethanolamines substituees et procede pour leur preparation
GB1301134A (en) * 1970-07-18 1972-12-29 Pfizer Ltd SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
IL57670A (en) * 1978-07-03 1982-11-30 Lilly Co Eli Phenethanolamines,their preparation and pharmaceutical formulations comprising them
EP0021636B1 (fr) * 1979-06-16 1982-12-01 Beecham Group Plc Amines secondaires, leur préparation et utilisation dans des compositions pharmaceutiques
DD157796A5 (de) * 1979-12-04 1982-12-08 Ciba Geigy Ag Verfahren zur herstellung neuer derivate des 2-amino-aethanols
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
DE3566886D1 (en) * 1984-05-04 1989-01-26 Upjohn Co N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use
US4569801A (en) * 1984-10-15 1986-02-11 Eli Lilly And Company Alkylsulfonamidophenylalkylamines

Also Published As

Publication number Publication date
PL265418A1 (en) 1988-07-21
EG18188A (en) 1992-09-30
EP0245997A2 (fr) 1987-11-19
DK175096B1 (da) 2004-06-01
AU578557B2 (en) 1988-10-27
LV5715A4 (lv) 1995-10-20
NO871820L (no) 1987-11-02
KR870011084A (ko) 1987-12-19
IE871165L (en) 1987-11-01
EP0245997B1 (fr) 1992-04-15
AU7226087A (en) 1987-11-19
IL82373A0 (en) 1987-10-30
DE10075004I2 (de) 2006-02-02
ES2033840T3 (es) 1993-04-01
FI88291C (fi) 1993-04-26
YU46541B (sh) 1993-11-16
PH23425A (en) 1989-08-07
NL300002I2 (nl) 2000-05-01
CN1019801B (zh) 1992-12-30
YU78387A (en) 1988-08-31
PT84782A (en) 1987-05-01
NO2001011I1 (no) 2001-07-16
NO168527C (no) 1992-03-04
HU196743B (en) 1989-01-30
DE3778201D1 (de) 1992-05-21
KR930001339B1 (ko) 1993-02-26
YU46195B (sh) 1993-05-28
DE10075004I1 (de) 2000-04-13
CA1289140C (fr) 1991-09-17
KR920014397A (ko) 1992-07-30
FI871898A (fi) 1987-11-02
IE59366B1 (en) 1994-02-09
MY111142A (en) 1999-09-30
GR3004457T3 (fr) 1993-03-31
BA98211B1 (bs) 1999-08-02
ATE74906T1 (de) 1992-05-15
HUT43558A (en) 1987-11-30
DK220287A (da) 1987-11-02
PL149924B1 (en) 1990-04-30
US4959366A (en) 1990-09-25
CN87103300A (zh) 1987-11-11
FI871898A0 (fi) 1987-04-29
LU90519I2 (fr) 2000-04-10
US5079248A (en) 1992-01-07
NO168527B (no) 1991-11-25
IL82373A (en) 1992-01-15
NZ220151A (en) 1989-02-24
FI88291B (fi) 1993-01-15
NL300002I1 (nl) 2000-04-03
DK220287D0 (da) 1987-04-30
YU73588A (en) 1990-04-30
LV5715B4 (lv) 1996-02-20
NO871820D0 (no) 1987-04-30
EP0245997A3 (en) 1989-12-20
PT84782B (pt) 1989-12-29

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