AU716642B2 - Process for preparing intermediates for the synthesis of antifungal agents - Google Patents

Process for preparing intermediates for the synthesis of antifungal agents Download PDF

Info

Publication number
AU716642B2
AU716642B2 AU14101/97A AU1410197A AU716642B2 AU 716642 B2 AU716642 B2 AU 716642B2 AU 14101/97 A AU14101/97 A AU 14101/97A AU 1410197 A AU1410197 A AU 1410197A AU 716642 B2 AU716642 B2 AU 716642B2
Authority
AU
Australia
Prior art keywords
formula
diol
enzyme
reaction
anhydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU14101/97A
Other languages
English (en)
Other versions
AU1410197A (en
Inventor
Christopher M. Nielsen
Anantha Sudhakar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU1410197A publication Critical patent/AU1410197A/en
Application granted granted Critical
Publication of AU716642B2 publication Critical patent/AU716642B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Casting Devices For Molds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU14101/97A 1995-12-20 1996-12-18 Process for preparing intermediates for the synthesis of antifungal agents Ceased AU716642B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57533495A 1995-12-20 1995-12-20
US08/575334 1995-12-20
PCT/US1996/019423 WO1997022710A1 (en) 1995-12-20 1996-12-18 Process for preparing intermediates for the synthesis of antifungal agents

Publications (2)

Publication Number Publication Date
AU1410197A AU1410197A (en) 1997-07-20
AU716642B2 true AU716642B2 (en) 2000-03-02

Family

ID=24299896

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14101/97A Ceased AU716642B2 (en) 1995-12-20 1996-12-18 Process for preparing intermediates for the synthesis of antifungal agents

Country Status (20)

Country Link
EP (1) EP0868525B1 (cs)
JP (4) JP2000501946A (cs)
KR (1) KR100456181B1 (cs)
CN (1) CN1090240C (cs)
AT (1) ATE232906T1 (cs)
AU (1) AU716642B2 (cs)
BR (1) BR9612082A (cs)
CA (1) CA2240408C (cs)
CZ (1) CZ292649B6 (cs)
DE (1) DE69626308T2 (cs)
DK (1) DK0868525T3 (cs)
ES (1) ES2187684T3 (cs)
HU (1) HU225765B1 (cs)
IL (2) IL125005A0 (cs)
MX (1) MX9804958A (cs)
NO (1) NO320154B1 (cs)
NZ (1) NZ325566A (cs)
PL (1) PL185775B1 (cs)
SK (1) SK284149B6 (cs)
WO (1) WO1997022710A1 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003277139A1 (en) 2002-10-03 2004-04-23 Wyeth Holdings Corporation Process for preparing monoprotected diols from symmetric diols
WO2011144657A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Purification of posaconazole and posaconazole intermediates
RU2580318C2 (ru) 2010-05-19 2016-04-10 Сандоз Аг Получение промежуточных продуктов для синтеза позаконазола
MX342850B (es) 2010-05-19 2016-10-14 Sandoz Ag Proceso para la preparacion de triazolonas quirales.
EP2571847B1 (en) 2010-05-19 2016-09-21 Sandoz AG Process for the preparation of chiral hydrazides
CN103635465A (zh) 2011-06-16 2014-03-12 桑多斯股份公司 制备手性化合物的方法
EP2789610A1 (en) 2013-04-10 2014-10-15 Sandoz Ag Purification of Posaconazole Intermediates
CN108727196A (zh) * 2018-07-23 2018-11-02 安徽华星化工有限公司 一种生产2-甲基-4-氯苯氧乙酸的酯类的方法
CN115448912B (zh) * 2022-10-12 2023-09-12 四川澄华生物科技有限公司 泊沙康唑中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3978193A (en) * 1992-05-01 1993-11-29 Cognis, Inc. Process of preparing enriched enantiomers of glycerol carbonate and derivatives thereof for synthesis of beta -blockers
US5403937A (en) * 1993-04-30 1995-04-04 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents
US5442093A (en) * 1994-05-09 1995-08-15 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents

Also Published As

Publication number Publication date
HUP9902113A2 (hu) 1999-11-29
NO320154B1 (no) 2005-11-07
NZ325566A (en) 1999-05-28
DE69626308T2 (de) 2003-07-24
KR20000064470A (ko) 2000-11-06
CN1090240C (zh) 2002-09-04
PL327456A1 (en) 1998-12-07
JP2000501946A (ja) 2000-02-22
ATE232906T1 (de) 2003-03-15
DK0868525T3 (da) 2003-04-07
BR9612082A (pt) 1999-05-11
JP2007020573A (ja) 2007-02-01
IL125005A (en) 2006-04-10
AU1410197A (en) 1997-07-20
NO982880L (no) 1998-06-19
PL185775B1 (pl) 2003-07-31
JP2008259512A (ja) 2008-10-30
CZ191698A3 (cs) 1998-10-14
ES2187684T3 (es) 2003-06-16
CN1209171A (zh) 1999-02-24
HUP9902113A3 (en) 2001-02-28
CA2240408C (en) 2007-04-24
CA2240408A1 (en) 1997-06-26
CZ292649B6 (cs) 2003-11-12
JP2011139715A (ja) 2011-07-21
HU225765B1 (en) 2007-08-28
DE69626308D1 (de) 2003-03-27
HK1010563A1 (en) 1999-06-25
EP0868525B1 (en) 2003-02-19
NO982880D0 (no) 1998-06-19
SK284149B6 (sk) 2004-10-05
MX9804958A (es) 1998-09-30
IL125005A0 (en) 1999-01-26
EP0868525A1 (en) 1998-10-07
JP4906785B2 (ja) 2012-03-28
WO1997022710A1 (en) 1997-06-26
SK86498A3 (en) 1999-01-11
KR100456181B1 (ko) 2004-12-31

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SREP Specification republished