SK284149B6 - Spôsob prípravy kryštalického chirálneho hydroxyesteru na syntézu činidiel pôsobiacich proti hubám - Google Patents

Spôsob prípravy kryštalického chirálneho hydroxyesteru na syntézu činidiel pôsobiacich proti hubám Download PDF

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Publication number
SK284149B6
SK284149B6 SK864-98A SK86498A SK284149B6 SK 284149 B6 SK284149 B6 SK 284149B6 SK 86498 A SK86498 A SK 86498A SK 284149 B6 SK284149 B6 SK 284149B6
Authority
SK
Slovakia
Prior art keywords
formula
diol
reaction
weight
enzyme
Prior art date
Application number
SK864-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK86498A3 (en
Inventor
Christopher M. Nielsen
Anantha Sudhakar
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of SK86498A3 publication Critical patent/SK86498A3/sk
Publication of SK284149B6 publication Critical patent/SK284149B6/sk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62Halogen-containing esters
    • C07C69/65Halogen-containing esters of unsaturated acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Casting Devices For Molds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK864-98A 1995-12-20 1996-12-18 Spôsob prípravy kryštalického chirálneho hydroxyesteru na syntézu činidiel pôsobiacich proti hubám SK284149B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57533495A 1995-12-20 1995-12-20
PCT/US1996/019423 WO1997022710A1 (en) 1995-12-20 1996-12-18 Process for preparing intermediates for the synthesis of antifungal agents

Publications (2)

Publication Number Publication Date
SK86498A3 SK86498A3 (en) 1999-01-11
SK284149B6 true SK284149B6 (sk) 2004-10-05

Family

ID=24299896

Family Applications (1)

Application Number Title Priority Date Filing Date
SK864-98A SK284149B6 (sk) 1995-12-20 1996-12-18 Spôsob prípravy kryštalického chirálneho hydroxyesteru na syntézu činidiel pôsobiacich proti hubám

Country Status (20)

Country Link
EP (1) EP0868525B1 (cs)
JP (4) JP2000501946A (cs)
KR (1) KR100456181B1 (cs)
CN (1) CN1090240C (cs)
AT (1) ATE232906T1 (cs)
AU (1) AU716642B2 (cs)
BR (1) BR9612082A (cs)
CA (1) CA2240408C (cs)
CZ (1) CZ292649B6 (cs)
DE (1) DE69626308T2 (cs)
DK (1) DK0868525T3 (cs)
ES (1) ES2187684T3 (cs)
HU (1) HU225765B1 (cs)
IL (2) IL125005A0 (cs)
MX (1) MX9804958A (cs)
NO (1) NO320154B1 (cs)
NZ (1) NZ325566A (cs)
PL (1) PL185775B1 (cs)
SK (1) SK284149B6 (cs)
WO (1) WO1997022710A1 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003277139A1 (en) 2002-10-03 2004-04-23 Wyeth Holdings Corporation Process for preparing monoprotected diols from symmetric diols
WO2011144657A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Purification of posaconazole and posaconazole intermediates
RU2580318C2 (ru) 2010-05-19 2016-04-10 Сандоз Аг Получение промежуточных продуктов для синтеза позаконазола
MX342850B (es) 2010-05-19 2016-10-14 Sandoz Ag Proceso para la preparacion de triazolonas quirales.
EP2571847B1 (en) 2010-05-19 2016-09-21 Sandoz AG Process for the preparation of chiral hydrazides
CN103635465A (zh) 2011-06-16 2014-03-12 桑多斯股份公司 制备手性化合物的方法
EP2789610A1 (en) 2013-04-10 2014-10-15 Sandoz Ag Purification of Posaconazole Intermediates
CN108727196A (zh) * 2018-07-23 2018-11-02 安徽华星化工有限公司 一种生产2-甲基-4-氯苯氧乙酸的酯类的方法
CN115448912B (zh) * 2022-10-12 2023-09-12 四川澄华生物科技有限公司 泊沙康唑中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3978193A (en) * 1992-05-01 1993-11-29 Cognis, Inc. Process of preparing enriched enantiomers of glycerol carbonate and derivatives thereof for synthesis of beta -blockers
US5403937A (en) * 1993-04-30 1995-04-04 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents
US5442093A (en) * 1994-05-09 1995-08-15 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents

Also Published As

Publication number Publication date
HUP9902113A2 (hu) 1999-11-29
NO320154B1 (no) 2005-11-07
NZ325566A (en) 1999-05-28
DE69626308T2 (de) 2003-07-24
KR20000064470A (ko) 2000-11-06
CN1090240C (zh) 2002-09-04
PL327456A1 (en) 1998-12-07
JP2000501946A (ja) 2000-02-22
ATE232906T1 (de) 2003-03-15
DK0868525T3 (da) 2003-04-07
BR9612082A (pt) 1999-05-11
JP2007020573A (ja) 2007-02-01
IL125005A (en) 2006-04-10
AU1410197A (en) 1997-07-20
NO982880L (no) 1998-06-19
PL185775B1 (pl) 2003-07-31
AU716642B2 (en) 2000-03-02
JP2008259512A (ja) 2008-10-30
CZ191698A3 (cs) 1998-10-14
ES2187684T3 (es) 2003-06-16
CN1209171A (zh) 1999-02-24
HUP9902113A3 (en) 2001-02-28
CA2240408C (en) 2007-04-24
CA2240408A1 (en) 1997-06-26
CZ292649B6 (cs) 2003-11-12
JP2011139715A (ja) 2011-07-21
HU225765B1 (en) 2007-08-28
DE69626308D1 (de) 2003-03-27
HK1010563A1 (en) 1999-06-25
EP0868525B1 (en) 2003-02-19
NO982880D0 (no) 1998-06-19
MX9804958A (es) 1998-09-30
IL125005A0 (en) 1999-01-26
EP0868525A1 (en) 1998-10-07
JP4906785B2 (ja) 2012-03-28
WO1997022710A1 (en) 1997-06-26
SK86498A3 (en) 1999-01-11
KR100456181B1 (ko) 2004-12-31

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Legal Events

Date Code Title Description
TC4A Change of owner's name

Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20121108

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20141218