AU623853B2 - Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents - Google Patents

Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents Download PDF

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Publication number
AU623853B2
AU623853B2 AU14643/88A AU1464388A AU623853B2 AU 623853 B2 AU623853 B2 AU 623853B2 AU 14643/88 A AU14643/88 A AU 14643/88A AU 1464388 A AU1464388 A AU 1464388A AU 623853 B2 AU623853 B2 AU 623853B2
Authority
AU
Australia
Prior art keywords
sucralfate
gel
suspension
solution
suspending agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU14643/88A
Other languages
English (en)
Other versions
AU1464388A (en
Inventor
Carla Marcella Caramella
Paolo Colombo
Ubaldo Conte
Gianni Zagnoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lisapharma SpA
Original Assignee
Lisapharma SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lisapharma SpA filed Critical Lisapharma SpA
Publication of AU1464388A publication Critical patent/AU1464388A/en
Application granted granted Critical
Publication of AU623853B2 publication Critical patent/AU623853B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Stereo-Broadcasting Methods (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Lift-Guide Devices, And Elevator Ropes And Cables (AREA)
AU14643/88A 1987-04-15 1988-04-14 Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents Ceased AU623853B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20129/87A IT1203901B (it) 1987-04-15 1987-04-15 Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti
IT20129/87 1987-04-15

Publications (2)

Publication Number Publication Date
AU1464388A AU1464388A (en) 1988-10-20
AU623853B2 true AU623853B2 (en) 1992-05-28

Family

ID=11164041

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14643/88A Ceased AU623853B2 (en) 1987-04-15 1988-04-14 Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents

Country Status (20)

Country Link
US (1) US5321013A (enExample)
EP (1) EP0286978B1 (enExample)
JP (1) JPS6445312A (enExample)
KR (1) KR930006037B1 (enExample)
CN (1) CN1021629C (enExample)
AT (1) ATE58144T1 (enExample)
AU (1) AU623853B2 (enExample)
CA (1) CA1306945C (enExample)
DE (1) DE3860967D1 (enExample)
DK (1) DK175683B1 (enExample)
ES (1) ES2021781B3 (enExample)
FI (1) FI88257C (enExample)
GR (1) GR3002515T3 (enExample)
IE (1) IE61339B1 (enExample)
IN (1) IN169494B (enExample)
IT (1) IT1203901B (enExample)
MX (1) MX11135A (enExample)
NO (1) NO174656C (enExample)
NZ (1) NZ224253A (enExample)
ZA (1) ZA882476B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2735559B2 (ja) * 1988-03-02 1998-04-02 中外製薬株式会社 懸濁液
IT1230157B (it) * 1989-06-16 1991-10-14 Lisapharma Spa Uso di sucralfato gel umido per il trattamento di ulcere del derma e come veicolo di farmaci ad attivita' topica
FR2657010B1 (fr) * 1990-01-12 1992-05-15 Pf Medicament Composition pharmaceutique sous forme de suspension aqueuse stable a base de sucrafalte et d'une substance anti-acide ainsi que son procede de preparation.
CA2090479C (en) * 1990-08-31 2002-01-15 Kiyoshige Ochi Stock solution of sucralfate suspended in water and production thereof
DK86492D0 (da) * 1992-06-30 1992-06-30 Bukh Meditec Laegemiddel
IT1264546B1 (it) * 1993-07-30 1996-10-02 Lisapharma Spa Composizione farmaceutica ad attivita' antiacida in forma di sospensione a base di gel di sucralfato
ATE213635T1 (de) * 1994-04-26 2002-03-15 Chugai Pharmaceutical Co Ltd Verfahren für die herstellung schmelz-granulierte sucralfatzubereitung
IT1274735B (it) * 1994-08-25 1997-07-24 Enosys S P A Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco
IT1284030B1 (it) * 1996-06-18 1998-05-08 Solchem Italiana Spa Metodo per la produzione di sospensioni acquose stabili, utili nelle composizioni farmaceutiche
IT1301969B1 (it) * 1998-07-30 2000-07-20 Lisapharma Spa Sucralfato gel secco granulare e poroso procedimento per la suapreparazione, e composizioni farmaceutiche solide che lo contengono
US6391860B1 (en) * 1999-09-09 2002-05-21 Mcgrath Patrick D. Method for preparation and use of paste formed by controlled reaction of sucralfate with hydrochloric acid
CN100425244C (zh) * 2004-04-14 2008-10-15 中国人民解放军总医院 注射用硫酸铝，用于治疗膀胱肿瘤的注射用硫酸铝注射液
CA2736884A1 (en) * 2008-09-17 2010-03-25 Patrick D. Mcgrath Antimicrobial sucralfate paste methods and compositions
WO2014151565A1 (en) 2013-03-15 2014-09-25 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
GR1008308B (el) 2013-05-31 2014-10-02 UNI-PHARMA ΚΛΕΩΝ ΤΣΕΤΗΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "UNI-PHARMA ABEE", Τοπικες φαρμακευτικες και ιατροτεχνολογικες συνθεσεις που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου ενυδατικου παραγοντα
JP6627485B2 (ja) * 2015-01-28 2020-01-08 ライオン株式会社 ゲル組成物及びその製造方法
JP6515680B2 (ja) * 2015-05-27 2019-05-22 ライオン株式会社 スクラルファート含有液状組成物
US10973846B2 (en) 2015-09-24 2021-04-13 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
FR3043556B1 (fr) * 2015-11-17 2020-01-10 Urgo Recherche Innovation Et Developpement Utilisation de composes oligosaccharidiques pour activer l'angiogenese
CN109431972B (zh) * 2018-11-20 2022-02-22 昆明积大制药股份有限公司 一种粒径为100nm—500nm的硫糖铝凝胶的成胶方法
CN114269386A (zh) 2019-06-10 2022-04-01 布里格姆及妇女医院股份有限公司 水活化的粘膜粘附性组合物和递送生物活性物质的方法
IT202100000059A1 (it) * 2021-01-04 2022-07-04 Nyuma Pharma Srl Nuove composizioni di sucralfato in alginato e loro utilizzo in terapia
CN118304859A (zh) * 2024-03-25 2024-07-09 康诺瑞达(福建)新药开发有限公司 一种硫糖铝混悬凝胶的制备方法以及检测其与蛋白亲和力的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3438284A (en) * 1984-08-22 1986-03-24 Merck Patent Gmbh Sucralfat-suspension
US4668665A (en) * 1982-10-27 1987-05-26 Chugai Seiyaku Kabushiki Kaisha Formulation of sucralfate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2512344A1 (fr) * 1981-09-08 1983-03-11 Af Aplicaciones Far Lab Procede de fabrication d'une suspension stable d'hydroxyde d'alumine et/ou d'hydroxyde de magnesie comme agent actif des antacida
DE3429263A1 (de) * 1984-08-08 1986-02-20 Gödecke AG, 1000 Berlin Verfahren zur stabilisierung filtrierbarer antacida mit hexitolen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668665A (en) * 1982-10-27 1987-05-26 Chugai Seiyaku Kabushiki Kaisha Formulation of sucralfate
AU3438284A (en) * 1984-08-22 1986-03-24 Merck Patent Gmbh Sucralfat-suspension

Also Published As

Publication number Publication date
KR930006037B1 (ko) 1993-07-03
FI88257B (fi) 1993-01-15
AU1464388A (en) 1988-10-20
FI881769A0 (fi) 1988-04-15
NZ224253A (en) 1991-03-26
IN169494B (enExample) 1991-10-26
JPS6445312A (en) 1989-02-17
DK175683B1 (da) 2005-01-17
MX11135A (es) 1993-12-01
EP0286978A1 (en) 1988-10-19
NO174656B (no) 1994-03-07
CN88102143A (zh) 1988-12-28
DE3860967D1 (de) 1990-12-13
IT1203901B (it) 1989-02-23
GR3002515T3 (en) 1993-01-25
NO881625L (no) 1988-10-17
ATE58144T1 (de) 1990-11-15
ES2021781B3 (es) 1991-11-16
EP0286978B1 (en) 1990-11-07
DK198488D0 (da) 1988-04-12
FI88257C (fi) 1993-04-26
CA1306945C (en) 1992-09-01
DK198488A (da) 1988-10-17
IE61339B1 (en) 1994-11-02
US5321013A (en) 1994-06-14
CN1021629C (zh) 1993-07-21
KR880012211A (ko) 1988-11-26
NO174656C (no) 1994-06-15
JPH0576927B2 (enExample) 1993-10-25
IE881038L (en) 1988-10-15
ZA882476B (en) 1988-09-29
IT8720129A0 (it) 1987-04-15
NO881625D0 (no) 1988-04-14
FI881769L (fi) 1988-10-16

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