AU612343B2 - A dry formulation for the preparation of a suspension of diclofenac in salt form; and a stable suspension produced therefrom - Google Patents

A dry formulation for the preparation of a suspension of diclofenac in salt form; and a stable suspension produced therefrom Download PDF

Info

Publication number
AU612343B2
AU612343B2 AU11102/88A AU1110288A AU612343B2 AU 612343 B2 AU612343 B2 AU 612343B2 AU 11102/88 A AU11102/88 A AU 11102/88A AU 1110288 A AU1110288 A AU 1110288A AU 612343 B2 AU612343 B2 AU 612343B2
Authority
AU
Australia
Prior art keywords
diclofenac
dry formulation
suspension
salt
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU11102/88A
Other languages
English (en)
Other versions
AU1110288A (en
Inventor
Leo Geller
Peter Glanzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU1110288A publication Critical patent/AU1110288A/en
Application granted granted Critical
Publication of AU612343B2 publication Critical patent/AU612343B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
AU11102/88A 1987-01-30 1988-01-29 A dry formulation for the preparation of a suspension of diclofenac in salt form; and a stable suspension produced therefrom Ceased AU612343B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH350/87A CH673395A5 (fi) 1987-01-30 1987-01-30
CH350/87 1987-01-30

Publications (2)

Publication Number Publication Date
AU1110288A AU1110288A (en) 1988-08-04
AU612343B2 true AU612343B2 (en) 1991-07-11

Family

ID=4185019

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11102/88A Ceased AU612343B2 (en) 1987-01-30 1988-01-29 A dry formulation for the preparation of a suspension of diclofenac in salt form; and a stable suspension produced therefrom

Country Status (26)

Country Link
JP (1) JPS63192716A (fi)
KR (1) KR880008808A (fi)
AT (1) AT397460B (fi)
AU (1) AU612343B2 (fi)
BE (1) BE1000442A4 (fi)
CA (1) CA1305058C (fi)
CH (1) CH673395A5 (fi)
DE (1) DE3802357A1 (fi)
DK (1) DK45588A (fi)
ES (1) ES2008420A6 (fi)
FI (1) FI880368A (fi)
FR (1) FR2611498B1 (fi)
GB (1) GB2201089B (fi)
GR (1) GR880100041A (fi)
IE (1) IE60453B1 (fi)
IT (1) IT1224241B (fi)
LU (1) LU87115A1 (fi)
MY (1) MY102662A (fi)
NL (1) NL8800231A (fi)
NO (1) NO880403L (fi)
NZ (1) NZ223343A (fi)
PH (1) PH23652A (fi)
PT (1) PT86644B (fi)
SE (1) SE8800228L (fi)
YU (1) YU15488A (fi)
ZA (1) ZA88638B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH675537A5 (fi) * 1988-03-25 1990-10-15 Ciba Geigy Ag
MX9201782A (es) * 1991-04-19 1992-10-01 Sandoz Ag Particulas de sustancias biologicamente activas, sustancialmente insolubles en agua, proceso para su produccion y composicion farmaceutica que las contiene.
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
GB9212450D0 (en) * 1992-06-11 1992-07-22 Indena Spa New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them
ZA949182B (en) * 1993-12-02 1995-07-26 South African Druggists Ltd Pharmaceutical composition
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
FR2793418B1 (fr) * 1999-05-11 2001-07-27 Synthelabo Formulations galeniques d'agents antithrombotiques pour administration sous-cutanee
GB0207529D0 (en) * 2002-04-02 2002-05-08 Norbrook Lab Ltd Injectable veterinary composition for small animals
JO3352B1 (ar) * 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0185374A2 (de) * 1984-12-21 1986-06-25 Merckle GmbH Flüssige Diclofenac-Zubereitungen
US4614741A (en) * 1983-07-05 1986-09-30 Troponwerke Gmbh & Co., Kg Depot antiinflammatory agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1373913A (en) * 1970-12-17 1974-11-13 Glaxo Lab Ltd Pharmaceutical compositions
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
EP0152379A3 (de) * 1984-02-15 1986-10-29 Ciba-Geigy Ag Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5002940A (en) * 1984-11-06 1991-03-26 Ciba-Geigy Corporation Solid drug formulations and stable suspensions
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
DE3607339A1 (de) * 1986-03-06 1987-09-10 Merck Patent Gmbh Pharmazeutische zubereitung

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614741A (en) * 1983-07-05 1986-09-30 Troponwerke Gmbh & Co., Kg Depot antiinflammatory agents
EP0185374A2 (de) * 1984-12-21 1986-06-25 Merckle GmbH Flüssige Diclofenac-Zubereitungen

Also Published As

Publication number Publication date
IE60453B1 (en) 1994-07-13
PT86644B (pt) 1992-01-31
LU87115A1 (fr) 1989-03-08
DE3802357A1 (de) 1988-08-11
DK45588A (da) 1988-07-31
ES2008420A6 (es) 1989-07-16
PH23652A (en) 1989-09-27
SE8800228L (sv) 1988-07-31
NZ223343A (en) 1990-03-27
FR2611498A1 (fr) 1988-09-09
MY102662A (en) 1992-08-17
NL8800231A (nl) 1988-08-16
KR880008808A (ko) 1988-09-13
GB2201089A (en) 1988-08-24
PT86644A (pt) 1988-02-01
CH673395A5 (fi) 1990-03-15
IT8847557A0 (it) 1988-08-21
GB8801737D0 (en) 1988-02-24
JPS63192716A (ja) 1988-08-10
NO880403L (no) 1988-08-01
FI880368A (fi) 1988-07-31
CA1305058C (en) 1992-07-14
GB2201089B (en) 1990-05-16
YU15488A (en) 1989-10-31
AU1110288A (en) 1988-08-04
NO880403D0 (no) 1988-01-29
ZA88638B (en) 1989-10-25
GR880100041A (el) 1988-12-16
IE880250L (en) 1988-07-30
FI880368A0 (fi) 1988-01-27
BE1000442A4 (fr) 1988-12-06
DK45588D0 (da) 1988-01-29
IT1224241B (it) 1990-09-26
ATA18588A (de) 1993-09-15
SE8800228D0 (sv) 1988-01-25
FR2611498B1 (fr) 1991-06-14
AT397460B (de) 1994-04-25

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