AU593051B2 - Method of treating alzheimer's disease - Google Patents

Method of treating alzheimer's disease Download PDF

Info

Publication number
AU593051B2
AU593051B2 AU67609/87A AU6760987A AU593051B2 AU 593051 B2 AU593051 B2 AU 593051B2 AU 67609/87 A AU67609/87 A AU 67609/87A AU 6760987 A AU6760987 A AU 6760987A AU 593051 B2 AU593051 B2 AU 593051B2
Authority
AU
Australia
Prior art keywords
galanthamine
disease
alzheimer
acid addition
per day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU67609/87A
Other languages
English (en)
Other versions
AU6760987A (en
Inventor
Bonnie Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25227312&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU593051(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of AU6760987A publication Critical patent/AU6760987A/en
Application granted granted Critical
Publication of AU593051B2 publication Critical patent/AU593051B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
AU67609/87A 1986-01-15 1987-01-15 Method of treating alzheimer's disease Expired AU593051B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/819,141 US4663318A (en) 1986-01-15 1986-01-15 Method of treating Alzheimer's disease
US819141 1986-01-15

Publications (2)

Publication Number Publication Date
AU6760987A AU6760987A (en) 1987-07-16
AU593051B2 true AU593051B2 (en) 1990-02-01

Family

ID=25227312

Family Applications (1)

Application Number Title Priority Date Filing Date
AU67609/87A Expired AU593051B2 (en) 1986-01-15 1987-01-15 Method of treating alzheimer's disease

Country Status (10)

Country Link
US (1) US4663318A (OSRAM)
EP (1) EP0236684B1 (OSRAM)
JP (1) JPH08778B2 (OSRAM)
AT (1) ATE76294T1 (OSRAM)
AU (1) AU593051B2 (OSRAM)
DE (3) DE3779149D1 (OSRAM)
ES (1) ES2000428T3 (OSRAM)
GR (2) GR880300077T1 (OSRAM)
LU (1) LU90710I2 (OSRAM)
NL (1) NL300140I2 (OSRAM)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0363415B1 (en) * 1987-05-04 2008-10-15 Davis, Bonnie Compounds for the treatment of alzheimer's disease
US6150354A (en) 1987-01-15 2000-11-21 Bonnie Davis Compounds for the treatment of Alzheimer's disease
IT1222395B (it) * 1987-07-30 1990-09-05 Pierrel Spa Composizione farmaceutica per somministrazione intranasale comprendente l'ormone ghrh,un agonista colinergico e/o un sale biliare
US4897388A (en) * 1988-12-20 1990-01-30 Geriatric Research Institute, Inc. Method of treating Alzheimer's disease
DE4010079A1 (de) * 1990-03-29 1991-10-02 Lohmann Therapie Syst Lts Pharmazeutische formulierung zur behandlung des alkoholismus
US5519017A (en) * 1990-03-29 1996-05-21 Lts Lohmann Therapie-Systeme Gmbh + Co. Kg Pharmaceutic formulation for the treatment of alcoholism
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
ES2134215T3 (es) * 1991-05-14 1999-10-01 Ernir Snorrason Tratamiento de sindromes de fatiga con inhibidores de colinesterasa.
US5177070A (en) * 1991-11-15 1993-01-05 Ciba-Geigy Corporation Method of treating physiologic male erectile impotence
DE4301783C1 (de) * 1993-01-23 1994-02-03 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Galanthamin als wirksamem Bestandteil
DE4301782C1 (de) * 1993-01-23 1994-08-25 Lohmann Therapie Syst Lts Verwendung von Galanthamin zur Behandlung der Nicotinabhängigkeit
US6323196B1 (en) * 1993-10-15 2001-11-27 Aventis Pharmaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US6316439B1 (en) 1993-10-15 2001-11-13 Aventis Pharamaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US6323195B1 (en) 1993-10-15 2001-11-27 Aventis Pharmaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
CN1069624C (zh) * 1994-10-21 2001-08-15 萨诺化学药物股份公司 4a,5,9,10,11,12-六氢-6H-苯并呋喃并[3a,3,2-ef][2]苯并吖庚因衍生物的制备方法
US6407229B1 (en) 1994-10-21 2002-06-18 Sanochemia Pharmazeutika Ag Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2] benzazapine
DE19509663A1 (de) 1995-03-17 1996-09-19 Lohmann Therapie Syst Lts Verfahren zur Isolierung von Galanthamin
GB9514821D0 (en) * 1995-07-19 1995-09-20 Sod Conseils Rech Applic Galanthamine derivatives
AT402691B (de) * 1996-01-26 1997-07-25 Sanochemia Ltd Verwendung von galanthamin zum herstellen von arzneimitteln zur behandlung von trisomie 21 oder verwandter trisomie-syndrome
AT403803B (de) 1996-04-19 1998-05-25 Sanochemia Ltd Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
TW506836B (en) * 1996-06-14 2002-10-21 Janssen Pharmaceutica Nv Fast-dissolving galanthamine hydrobromide tablet
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
AU2004242546B2 (en) * 1998-11-23 2008-05-15 Bonnie Davis Dosage formulations for acetylcholinesterase inhibitors
JP5558648B2 (ja) 1998-11-23 2014-07-23 デイビス、ボニー アセチルコリンエステラーゼ阻害剤のための投与製剤
EA004936B1 (ru) * 1998-12-24 2004-10-28 Янссен Фармацевтика Н.В. Препаративная форма галантамина с регулируемым выделением
US20050063998A1 (en) * 1999-10-26 2005-03-24 Francois Marc Karel Jozef Oral solution containing galantamine and a sweetening agent
US6426097B2 (en) 2000-01-28 2002-07-30 Herbaceuticals Inc. Herbal supplement for cognitive related impairment due to estrogen loss
WO2001054697A1 (en) * 2000-01-28 2001-08-02 Tricia Grose Herbal supplement for cognitive related impairment due to estrogen loss
HK1049832A1 (zh) 2000-03-31 2003-05-30 萨诺化学药物股份公司 雪花胺的新衍生物和类似物
CA2310926C (en) * 2000-04-03 2002-10-15 Janssen Pharmaceutica N.V. A use of galantamine for the treatment of neuropsychiatric behaviour associated with alzheimer's disease
CA2310990A1 (en) 2000-04-03 2000-10-09 Michael Pontecorvo A use of galantamine for the treatment of alzheimer's disease; targeting the underlying cause of the disease
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
JP4721386B2 (ja) * 2001-07-10 2011-07-13 第一三共株式会社 新規ガランタミン類縁体
US20030162770A1 (en) * 2002-02-22 2003-08-28 Davis Bonnie M. Use of modulators of nicotinic receptors for treatment of cognitive dysfunction
KR100935615B1 (ko) 2002-06-14 2010-01-07 토야마 케미칼 컴퍼니 리미티드 뇌기능을 개선하는 의약조성물 및 뇌기능을 개선하기 위한방법
US20040067934A1 (en) * 2002-10-03 2004-04-08 Parys Wim Louis Julien Use of galantamine for the treatment of neuropsychiatric behaviour associated with alzheimer's disease
MXPA04006900A (es) * 2002-10-24 2004-10-15 Merz Pharma Gmbh & Co Kgaa Politerapia que utiliza derivados de 1-aminociclohexano e inhibidores de acetilcolinesterasa.
US20040097484A1 (en) * 2002-11-14 2004-05-20 Marc Cantillion Once a day galantamine pharmaceutical compositions and methods of use
EP1603548A4 (en) * 2003-02-05 2007-10-10 Myriad Genetics Inc METHOD AND COMPOSITION FOR THE TREATMENT OF NEURODEEGENERATIVE DISEASES
EP1628532A2 (en) * 2003-05-30 2006-03-01 Microbia, Inc. Methods for the protection of memory and cognition
US20050048543A1 (en) * 2003-07-11 2005-03-03 Jeroen Aerssens CHRNA2 genetic markers associated with galantamine response
WO2005065069A2 (en) * 2003-07-11 2005-07-21 Myriad Genetics, Inc. Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
ATE374030T1 (de) * 2003-07-25 2007-10-15 Hoffmann La Roche Kombination eines mglur2 antagonists und eines ache inhibitors zur behandlung von akuten und/oder chronischen neurologischen krankheiten
US20050260613A1 (en) * 2003-10-28 2005-11-24 Genaissance Pharmaceuticals LRPAP1 genetic markers associated with galantamine
BG65658B1 (bg) * 2003-11-13 2009-05-29 "Софарма" Ад Комбиниран лекарствен продукт на основата на галантамин
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
US7250258B2 (en) * 2003-12-15 2007-07-31 Pgxhealth Llc CDK5 genetic markers associated with galantamine response
US20050142193A1 (en) * 2003-12-31 2005-06-30 Lijuan Tang Galantamine formulations
EP1763337A2 (en) * 2003-12-31 2007-03-21 Actavis Group HF Immediate, controlled and sustained release formulations of galanthamine
RU2397762C2 (ru) * 2004-02-19 2010-08-27 Новартис Аг Применение ингибиторов холинэстеразы для лечения сосудистой депрессии
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
CN1946906A (zh) * 2004-04-29 2007-04-11 吉斯通护岸系统股份有限公司 用于墙、护墙和类似物的饰面
EP1750724A4 (en) * 2004-05-14 2008-01-23 Univ Johns Hopkins METHOD FOR ENHANCING COGNITIVE FUNCTION USING CO-ADMINISTRATION OF GABAB RECEPTOR ANTAGONIST AND ACETYLCHOLINESTERASE INHIBITOR
JPWO2006004201A1 (ja) * 2004-07-01 2008-04-24 エーザイ・アール・アンド・ディー・マネジメント株式会社 神経再生促進剤
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
ATE439347T1 (de) * 2004-11-23 2009-08-15 Warner Lambert Co 7-(2h-pyrazol-3-yl)-3,5-dihydroxy-heptansäure- derivate als hmg-co-a-reductase-inhibitoren zur behandlung von lipidemia
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
AU2005322611A1 (en) * 2004-12-23 2006-07-06 Voyager Pharmaceutical Corporation Leuprolide acetate and acetylcholinesterase inhibitors or NMDA receptor antagonists for the treatment of Alzheimer's disease
AU2006244297A1 (en) 2005-04-06 2006-11-16 Adamas Pharmaceuticals, Inc. Methods and compositions for treatment of CNS disorders
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
NZ564789A (en) * 2005-07-22 2010-07-30 Myriad Genetics Inc High drug load formulations and dosage forms
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
RU2009120048A (ru) 2006-10-27 2010-12-10 Медивэйшн Ньюролоджи, Инк. (Us) Способы и комбинированные средства для лечения болезни альцгеймера
US20110201597A1 (en) 2008-03-27 2011-08-18 Chase Thomas N Method and composition for treating alzheimer-type dementia
WO2011034568A1 (en) 2009-09-18 2011-03-24 Chase Pharmaceuticals Corporation Method and composition for treating alzheimer-type dementia
EP3178477A1 (en) 2008-03-27 2017-06-14 Chase Pharmaceuticals Corporation Combination of a nspacha (peripheral anticholinergic agent) like solifenacin and an achei (acetyl choline esterase inhibitor) like donepezil for treating dementia
BR112012012766A2 (pt) 2009-11-26 2016-09-06 Usv Ltd composicões farmacêuticas de galantamina de liberação controlada
EP2533645B1 (en) * 2010-02-09 2016-07-27 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2011151359A1 (en) 2010-06-02 2011-12-08 Noscira, S.A. Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative
FR2962335B1 (fr) 2010-07-12 2013-01-18 Cll Pharma Utilisation du nonapeptide pat dans le traitement et la prevention des maladies neurodegeneratives
US9561218B2 (en) 2012-09-05 2017-02-07 Chase Pharmaceuticals Corporation Anticholinergic neuroprotective composition and methods
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA
BG66818B1 (bg) 2013-03-07 2019-01-31 Berbee Beheer B. V. Състав на екстракт от hippeastrum papilio за производство на лекарствени средства и хранителни добавки
ES2881081T3 (es) 2013-03-15 2021-11-26 Agenebio Inc Procedimientos y composiciones para mejorar la función cognitiva
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
DK3033082T3 (da) 2013-08-16 2021-09-20 Univ Maastricht Behandling af kognitiv svækkelse med pde4-hæmmer
CN112843005B (zh) 2015-05-22 2023-02-21 艾吉因生物股份有限公司 左乙拉西坦的延时释放药物组合物

Also Published As

Publication number Publication date
GR880300077T1 (en) 1988-10-21
US4663318A (en) 1987-05-05
JPH08778B2 (ja) 1996-01-10
JPS62215527A (ja) 1987-09-22
EP0236684A3 (en) 1988-12-14
DE10199020I1 (de) 2001-05-23
DE3779149D1 (de) 1992-06-25
EP0236684A2 (en) 1987-09-16
ES2000428T9 (es) 2013-08-14
DE10199020I2 (de) 2004-05-06
EP0236684B1 (en) 1992-05-20
GR3005447T3 (OSRAM) 1993-05-24
ES2000428T3 (es) 1993-10-01
NL300140I1 (nl) 2004-02-02
LU90710I2 (fr) 2001-03-05
DE236684T1 (de) 1988-04-28
AU6760987A (en) 1987-07-16
NL300140I2 (nl) 2004-04-01
ES2000428A4 (es) 1988-03-01
ATE76294T1 (de) 1992-06-15

Similar Documents

Publication Publication Date Title
AU593051B2 (en) Method of treating alzheimer&#39;s disease
CA2226784C (en) Use of cgmp-phosphodiesterase inhibitors to treat impotence
JP2977912B2 (ja) 向精神薬の安定化溶液
US5750537A (en) Use of 5HT3 antagonist to treat impotence
CA1273879A (en) Pharmaceutical compositions and medical uses of dioxopiperidine derivatives
JPH06507621A (ja) ベンゾジアゼピンによる治療における改善
KR19990067527A (ko) 동통의 치료를 위한 에피나스틴의 용도
JPH04501267A (ja) 骨髄造血の刺激に有用なヘテロアリール―3―オキソ―プロパンニトリル誘導体
JPH05132430A (ja) 薬物従属症及び禁断症状の治療に関するグリシン/nmdaレセプターリガンドの用法
EP0190851B1 (en) Improved antiinflammatory composition
US6274621B1 (en) Ginkgolides for inhibition of membrane expression of benzodiazepine receptors
JP3243514B2 (ja) 療法―抵抗性精神分裂症治療用医薬
AU744261B2 (en) Use of NK-1 receptor antagonists for treating eating disorders
JPH0680009B2 (ja) 抗高血圧組み合わせ医薬
US4363809A (en) Organic compounds
WO1996033723A2 (en) Use of benzamide derivatives for treating and/or preventing meniere&#39;s syndrome and motion sickness
US4152435A (en) Compositions and methods to treat hypertension comprising a pyridazine and N-amidino-2-(2,6-dichlorophenyl) acetamide
US3780180A (en) N-substituted amino-n-nitroso-aminoace-tonitriles in the treatment of hypertension
US4225605A (en) Ergolene or ergoline compounds for treating congestive heart failure
AU724416B2 (en) Ginkgolides for inhibition of membrane expression
JPH11513386A (ja) β−受容体遮断薬とオピオイドとの新規な組合せ物
KR920703593A (ko) 이미다조퀴녹살린 화합물, 이의 제조방법 및 용도
JPH03170434A (ja) 抗ガン剤相乗剤
US3743746A (en) Process of treating peptic ulcer with a non-anticholinergic agent
CA1089765A (en) Antihypertensive composition