AU549981B2 - Zinc stabilized insulin - Google Patents

Zinc stabilized insulin

Info

Publication number
AU549981B2
AU549981B2 AU11136/83A AU1113683A AU549981B2 AU 549981 B2 AU549981 B2 AU 549981B2 AU 11136/83 A AU11136/83 A AU 11136/83A AU 1113683 A AU1113683 A AU 1113683A AU 549981 B2 AU549981 B2 AU 549981B2
Authority
AU
Australia
Prior art keywords
stabilized insulin
zinc stabilized
zinc
insulin
stabilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU11136/83A
Other languages
English (en)
Other versions
AU1113683A (en
Inventor
Jens Jorgen Vejlgaard Brange
Svend Havelund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of AU1113683A publication Critical patent/AU1113683A/en
Application granted granted Critical
Publication of AU549981B2 publication Critical patent/AU549981B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K13/00—Apparatus or processes specially adapted for manufacturing or adjusting assemblages of electric components
    • H05K13/06—Wiring by machine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU11136/83A 1982-02-05 1983-02-04 Zinc stabilized insulin Expired AU549981B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK491/82 1982-02-05
DK49182 1982-02-05

Publications (2)

Publication Number Publication Date
AU1113683A AU1113683A (en) 1983-08-11
AU549981B2 true AU549981B2 (en) 1986-02-20

Family

ID=8094159

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11136/83A Expired AU549981B2 (en) 1982-02-05 1983-02-04 Zinc stabilized insulin

Country Status (22)

Country Link
US (1) US4476118A (enExample)
JP (1) JPS58192818A (enExample)
AT (1) AT382780B (enExample)
AU (1) AU549981B2 (enExample)
BE (1) BE895832A (enExample)
CA (1) CA1203476A (enExample)
CH (1) CH657530A5 (enExample)
DE (1) DE3303860A1 (enExample)
ES (1) ES519533A0 (enExample)
FI (1) FI78616C (enExample)
FR (1) FR2521009B1 (enExample)
GB (1) GB2114573B (enExample)
GR (1) GR77388B (enExample)
IE (1) IE54548B1 (enExample)
IT (1) IT1178455B (enExample)
LU (1) LU84632A1 (enExample)
NL (1) NL187269C (enExample)
NO (1) NO161204C (enExample)
NZ (1) NZ203189A (enExample)
PT (1) PT76195B (enExample)
SE (1) SE460948B (enExample)
ZA (1) ZA83742B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU575951B2 (en) * 1984-06-09 1988-08-11 Hoechst Aktiengesellschaft Insulin preparation with thickening agent and surfactant

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2520262B2 (ja) * 1987-08-21 1996-07-31 春幸 川原 パツチテスト材料
US4789660A (en) * 1987-09-10 1988-12-06 American Home Products Corporation Insulin administration using methyl and propyl paraben
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5534488A (en) * 1993-08-13 1996-07-09 Eli Lilly And Company Insulin formulation
US5474978A (en) * 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
AR002976A1 (es) * 1995-03-31 1998-05-27 Lilly Co Eli Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas
AU7678196A (en) * 1995-11-13 1997-06-05 Minimed, Inc. Methods and compositions for the delivery of monomeric proteins
JP2000507812A (ja) * 1996-03-12 2000-06-27 ライフ テクノロジーズ，インコーポレイテッド 造血細胞培養栄養補充成分
DE59711533D1 (de) * 1996-07-26 2004-05-27 Aventis Pharma Gmbh Insulinderivate mit erhöhter Zinkbindung
SI0884053T1 (en) * 1997-06-13 2003-02-28 Eli Lilly And Company Stable insulin formulations
ZA984697B (en) 1997-06-13 1999-12-01 Lilly Co Eli Stable insulin formulations.
WO1999024015A1 (en) * 1997-11-12 1999-05-20 Alza Corporation Buffered drug formulations for transdermal electrotransport delivery
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
DE69920767T2 (de) * 1998-10-16 2006-02-02 Novo Nordisk A/S Stabile konzentrierte Insulin Präparationen zur pulmonaren Verabreichung
DE19930676B4 (de) * 1999-07-02 2006-01-19 Sanofi-Aventis Deutschland Gmbh Verfahren zur Stabilisierung von Insulin, Insulinderivaten und/oder deren Vorläufer in komplexen Mischungen bei deren Lagerung in wäßrigen Lösungsmitteln
DK1265630T3 (da) * 2000-03-24 2006-10-09 Genentech Inc Anvendelse af insulin til behandling af brusksygdomme
JP4147234B2 (ja) * 2004-09-27 2008-09-10 キヤノン株式会社 吐出用液体、吐出方法、カートリッジ及び吐出装置
WO2003094956A1 (en) 2002-05-07 2003-11-20 Novo Nordisk A/S Soluble formulations comprising monomeric insulin and acylated insulin
US20050065066A1 (en) * 2002-12-20 2005-03-24 Kaarsholm Niels Christian Stabilised insulin compositions
JP2006516966A (ja) * 2002-12-20 2006-07-13 ノボ　ノルディスク　アクティーゼルスカブ 安定化されたインスリン組成物
WO2004096266A1 (en) * 2003-05-02 2004-11-11 Novo Nordisk A/S Improved physical stability of insulin formulations
EP2107069B1 (en) * 2003-08-05 2013-01-16 Novo Nordisk A/S Novel insulin derivatives
CN103223160B (zh) 2004-07-19 2015-02-18 比奥孔有限公司 胰岛素-低聚物共轭物,制剂及其用途
US20090074882A1 (en) 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
US20090136538A1 (en) * 2006-05-22 2009-05-28 Jan Jezek Stable vaccine formulation
GB0700523D0 (en) * 2007-01-11 2007-02-21 Insense Ltd The Stabilisation Of Proteins
WO2008112706A1 (en) 2007-03-13 2008-09-18 Nutrition 21, Inc. Methods and compositions for the sustained release of chromium
JP5552046B2 (ja) * 2007-06-13 2014-07-16 ノボ・ノルデイスク・エー／エス インスリン誘導体を含有する薬学的製剤
WO2009002867A2 (en) 2007-06-26 2008-12-31 Nutrition 21, Inc. Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement
WO2009063072A2 (en) * 2007-11-16 2009-05-22 Novo Nordisk A/S Pharmaceutical compositions containing insulin and an insulinotropic peptide
EP2341940A1 (en) * 2008-07-16 2011-07-13 Arecor Limited The stabilisation of proteins
EP2328607A1 (en) * 2008-07-16 2011-06-08 Arecor Limited Stable formulation of a therapeutic protein
KR20110085985A (ko) * 2008-10-30 2011-07-27 노보 노르디스크 에이/에스 하루 한번 주사 빈도보다 적은 인슐린 주사를 사용한 진성 당뇨병의 치료
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
BR112013010345A2 (pt) 2010-10-27 2017-07-25 Novo Nordisk As tratamento de diabetes melitus usando as injeções de insulina administradas com intervalos de variação da injeção
ES2927800T3 (es) 2011-03-01 2022-11-11 Nutrition 21 Llc Composición de insulina y cromo para el tratamiento y la prevención de diabetes, hipoglicemia y trastornos relacionados
ES2670969T3 (es) 2012-11-13 2018-06-04 Adocia Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido
MX360420B (es) * 2012-12-19 2018-10-31 Wockhardt Ltd Una composicion acuosa estable que comprende insulina humana o un analogo o derivado de la misma.
BR112015013223A2 (pt) 2012-12-26 2017-07-11 Wockhardt Ltd composição farmacêutica
TWI641381B (zh) * 2013-02-04 2018-11-21 法商賽諾菲公司 胰島素類似物及／或胰島素衍生物之穩定化醫藥調配物
JP2016519127A (ja) 2013-04-30 2016-06-30 ノヴォ ノルディスク アー／エス 新規投与レジメン
WO2015084694A2 (en) * 2013-12-04 2015-06-11 Merck Sharp & Dohme Corp. Method for preparing crystalline insulin
TW201630622A (zh) 2014-12-16 2016-09-01 美國禮來大藥廠 速效胰島素組合物
JO3749B1 (ar) 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
GB2564295A (en) 2016-02-11 2019-01-09 Nutrition 21 Llc Chromium containing compositions for improving health and fitness
EP3518893A1 (en) 2016-09-29 2019-08-07 Arecor Limited Novel formulations
KR20190140048A (ko) 2017-06-01 2019-12-18 일라이 릴리 앤드 캄파니 신속-작용 인슐린 조성물
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation
CN114887039B (zh) * 2022-05-13 2026-01-30 西北工业大学 一种锌离子介导的自组装胰岛素纳米药物、制备方法和应用
CN120142500B (zh) * 2025-02-28 2025-10-10 中国计量科学研究院 一种具有互换性的活性人胰岛素溶液标准物质及其制备方法和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2882202A (en) * 1950-04-05 1959-04-14 Novo Terapeutisk Labor As Insulin crystal preparations and methods of producing them
US2787575A (en) * 1950-11-22 1957-04-02 Organon Zinc-glycine-insulin composition and production thereof
US2882203A (en) * 1951-06-26 1959-04-14 Novo Terapeutisk Labor As Injectable insulin preparation with protracted effect
DE1044360B (de) * 1953-08-19 1958-11-20 Roskilde Medical Company Ltd R Verfahren zur Herstellung von Zinkinsulin mit erhoehtem Zinkgehalt
DE956098C (de) * 1954-02-18 1957-01-10 Dr Dr Guenther Weitzel Verfahren zur Herstellung zinkreicher Insulin-Komplexverbindungen
US3058885A (en) * 1957-06-08 1962-10-16 Novo Terapeutisk Labor As Process for treatment of insulin crystals and for production of insulin preparationstherefrom
US3014842A (en) * 1957-08-10 1961-12-26 Novo Terapeutish Lab A S Injectable bovine insulin crystal suspensions and process of producing same
US3091573A (en) * 1958-05-12 1963-05-28 Novo Terapeutisk Labor As Quick acting insulin preparation
FR1263220A (fr) * 1958-08-01 1961-06-09 Novo Terapeutisk Labor As Procédé de production d'une préparation d'insuline à action rapide
DK116527B (da) * 1967-03-01 1970-01-19 Nordisk Insulinlab Fremgangsmåde til fremstilling af en hurtigtvirkende, holdbar, neutral opløsning af rent krystallinsk okseinsulin eller okseinsulin, der ved tilsætning af Zn er krystalliserbart i vand, eller blandinger af okseinsulin og insulin af anden oprindelse.
GB1285023A (en) * 1968-08-09 1972-08-09 Novo Terapeutisk Labor As Improvements in or relating to injectable insulin preparations
US3657425A (en) * 1969-03-12 1972-04-18 Burroughs Wellcome Co Beef insulin preparations
DE2459515C3 (de) * 1974-12-17 1982-02-11 Hoechst Ag, 6000 Frankfurt Arzneimittelzubereitungen mit antidiabetischer Wirkung
EP0018609B1 (de) * 1979-04-30 1983-09-21 Hoechst Aktiengesellschaft Gegen Denaturierung beständige, wässrige Protein-Lösungen, Verfahren zu ihrer Herstellung und ihre Verwendung
DK80781A (da) * 1980-02-29 1981-08-30 Hospital For Sick Children Oploesninger af polypeptider
WO1983003054A1 (en) * 1982-03-03 1983-09-15 Johansen, Kristian, Betton A proces for producing an insulin preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU575951B2 (en) * 1984-06-09 1988-08-11 Hoechst Aktiengesellschaft Insulin preparation with thickening agent and surfactant

Also Published As

Publication number Publication date
AT382780B (de) 1987-04-10
BE895832A (fr) 1983-08-04
ES8500060A1 (es) 1984-10-16
NL8300440A (nl) 1983-09-01
IE54548B1 (en) 1989-11-08
NL187269C (nl) 1991-08-01
GB2114573B (en) 1985-05-01
DE3303860A1 (de) 1983-08-18
SE8300598L (sv) 1983-08-06
NO161204C (no) 1989-07-19
IT8319420A0 (it) 1983-02-04
NO830385L (no) 1983-08-08
LU84632A1 (fr) 1983-09-08
NL187269B (nl) 1991-03-01
AU1113683A (en) 1983-08-11
ATA38983A (de) 1986-09-15
US4476118A (en) 1984-10-09
IT1178455B (it) 1987-09-09
IE830220L (en) 1983-08-05
PT76195A (en) 1983-03-01
FR2521009B1 (fr) 1987-07-17
ZA83742B (en) 1983-11-30
NZ203189A (en) 1985-07-31
PT76195B (en) 1986-01-27
GB2114573A (en) 1983-08-24
GR77388B (enExample) 1984-09-11
FI78616C (fi) 1989-09-11
CH657530A5 (de) 1986-09-15
DE3303860C2 (enExample) 1989-12-28
JPH0367056B2 (enExample) 1991-10-21
SE8300598D0 (sv) 1983-02-04
SE460948B (sv) 1989-12-11
FI830375L (fi) 1983-08-06
FI830375A0 (fi) 1983-02-03
NO161204B (no) 1989-04-10
ES519533A0 (es) 1984-10-16
FI78616B (fi) 1989-05-31
GB8303133D0 (en) 1983-03-09
CA1203476A (en) 1986-04-22
FR2521009A1 (fr) 1983-08-12
JPS58192818A (ja) 1983-11-10

Similar Documents

Publication Publication Date Title
AU1113683A (en) Zinc stabilized insulin
AU567303B2 (en) Barrel cordlock
AU569849B2 (en) Syringe
AU551549B2 (en) Quadricycle
AU552422B2 (en) Syringe
AU537128B2 (en) Buckle
AU560073B2 (en) Spergualin-related compounds
AU1475883A (en) Dosierpumpe
AU8194387A (en) Acetylcinnamate compounds
AU1476983A (en) Bomanordning
AU2956584A (en) Stabilized 2-mercaptopyridine-i-oxide
AU2231083A (en) 1-fluro-1-aryloxy-2-azolylmethyl-2-alkanols
AU1568583A (en) Multi-carbamates insecticides
AU7531081A (en) Self-destructible syringes
AU553665B2 (en) 2-beta-d-ribofuranosylselenazole-4-carboxamide compounds
AU1825983A (en) Skjellklase-skilleanordning
AU552790B2 (en) Stabilized polycarbonate composition
AU1777983A (en) Anesthetic-antipruritic compounds
AU2175183A (en) Pyridylalkylamino-pyrimidones
AU563551B2 (en) Injector
AU1314983A (en) Thieno-containing compounds
AU2343984A (en) Rohrtrenner
AU563468B2 (en) Injector
AU533828B3 (en) Mussell farming
AU1195583A (en) Medicament based on l-methionine

Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired