NL187269B - Water bevattende oplossing van monocomponent-insuline en zinkionen. - Google Patents

Water bevattende oplossing van monocomponent-insuline en zinkionen.

Info

Publication number
NL187269B
NL187269B NLAANVRAGE8300440,A NL8300440A NL187269B NL 187269 B NL187269 B NL 187269B NL 8300440 A NL8300440 A NL 8300440A NL 187269 B NL187269 B NL 187269B
Authority
NL
Netherlands
Prior art keywords
water
containing solution
zinc ions
monocomponent insulin
monocomponent
Prior art date
Application number
NLAANVRAGE8300440,A
Other languages
English (en)
Other versions
NL8300440A (nl
NL187269C (nl
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Publication of NL8300440A publication Critical patent/NL8300440A/nl
Publication of NL187269B publication Critical patent/NL187269B/nl
Application granted granted Critical
Publication of NL187269C publication Critical patent/NL187269C/nl

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K13/00—Apparatus or processes specially adapted for manufacturing or adjusting assemblages of electric components
    • H05K13/06—Wiring by machine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
NLAANVRAGE8300440,A 1982-02-05 1983-02-04 Water bevattende oplossing van monocomponent-insuline en zinkionen. NL187269C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK49182 1982-02-05
DK49182 1982-02-05

Publications (3)

Publication Number Publication Date
NL8300440A NL8300440A (nl) 1983-09-01
NL187269B true NL187269B (nl) 1991-03-01
NL187269C NL187269C (nl) 1991-08-01

Family

ID=8094159

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE8300440,A NL187269C (nl) 1982-02-05 1983-02-04 Water bevattende oplossing van monocomponent-insuline en zinkionen.

Country Status (22)

Country Link
US (1) US4476118A (nl)
JP (1) JPS58192818A (nl)
AT (1) AT382780B (nl)
AU (1) AU549981B2 (nl)
BE (1) BE895832A (nl)
CA (1) CA1203476A (nl)
CH (1) CH657530A5 (nl)
DE (1) DE3303860A1 (nl)
ES (1) ES519533A0 (nl)
FI (1) FI78616C (nl)
FR (1) FR2521009B1 (nl)
GB (1) GB2114573B (nl)
GR (1) GR77388B (nl)
IE (1) IE54548B1 (nl)
IT (1) IT1178455B (nl)
LU (1) LU84632A1 (nl)
NL (1) NL187269C (nl)
NO (1) NO161204C (nl)
NZ (1) NZ203189A (nl)
PT (1) PT76195B (nl)
SE (1) SE460948B (nl)
ZA (1) ZA83742B (nl)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE50502T1 (de) * 1984-06-09 1990-03-15 Hoechst Ag Insulinzubereitungen, verfahren zu deren herstellung und deren verwendung.
JP2520262B2 (ja) * 1987-08-21 1996-07-31 春幸 川原 パツチテスト材料
US4789660A (en) * 1987-09-10 1988-12-06 American Home Products Corporation Insulin administration using methyl and propyl paraben
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5534488A (en) * 1993-08-13 1996-07-09 Eli Lilly And Company Insulin formulation
US5474978A (en) * 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
YU18596A (sh) * 1995-03-31 1998-07-10 Eli Lilly And Company Analogne formulacije monomernog insulina
CA2236579C (en) * 1995-11-13 2009-06-30 Minimed, Inc. Methods and compositions for the delivery of monomeric proteins
EP0891419A4 (en) * 1996-03-12 2000-03-01 Life Technologies Inc NUTRIENT ADDITIVE FOR HEMATOPOETIC CELL CULTURES
DK0821006T3 (da) * 1996-07-26 2004-08-16 Aventis Pharma Gmbh Insulinderivater med öget zinkbinding
PE79099A1 (es) * 1997-06-13 1999-08-24 Lilly Co Eli Formulaciones de insulina estables
DK1283051T3 (da) * 1997-06-13 2006-10-16 Lilly Co Eli Stabile insulinformuleringer
WO1999024071A1 (en) * 1997-11-12 1999-05-20 Alza Corporation Method for decreasing self-association of polypeptides
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
ATE277630T1 (de) * 1998-10-16 2004-10-15 Novo Nordisk As Stabile konzentrierte insulin präparationen zur pulmonaren verabreichung
DE19930676B4 (de) * 1999-07-02 2006-01-19 Sanofi-Aventis Deutschland Gmbh Verfahren zur Stabilisierung von Insulin, Insulinderivaten und/oder deren Vorläufer in komplexen Mischungen bei deren Lagerung in wäßrigen Lösungsmitteln
WO2001072323A2 (en) * 2000-03-24 2001-10-04 Genentech, Inc. Use of insulin for the treatment of cartilagenous disorders
JP4147234B2 (ja) * 2004-09-27 2008-09-10 キヤノン株式会社 吐出用液体、吐出方法、カートリッジ及び吐出装置
JP5599543B2 (ja) 2002-05-07 2014-10-01 ノヴォ ノルディスク アー／エス 単量体インスリン及びアシル化インスリンを含む可溶性製剤
US20050065066A1 (en) * 2002-12-20 2005-03-24 Kaarsholm Niels Christian Stabilised insulin compositions
EP1585541B1 (en) * 2002-12-20 2007-11-14 Novo Nordisk A/S Pharmaceutical compositions comprising insulin and legends of insulin hexamer
WO2004096266A1 (en) * 2003-05-02 2004-11-11 Novo Nordisk A/S Improved physical stability of insulin formulations
EP2264065B1 (en) * 2003-08-05 2017-03-08 Novo Nordisk A/S Novel insulin derivatives
UA103758C2 (ru) 2004-07-19 2013-11-25 Биокон Лимитед Конъюгаты олигомеров инсулина, их композиции и применение
PT1969004E (pt) 2005-12-28 2011-11-25 Novo Nordisk As Composições que compreendem uma insulina acilada e zinco e método para criar tais composições
US20090136538A1 (en) * 2006-05-22 2009-05-28 Jan Jezek Stable vaccine formulation
GB0700523D0 (en) * 2007-01-11 2007-02-21 Insense Ltd The Stabilisation Of Proteins
EP2134351B1 (en) 2007-03-13 2016-04-27 Nutrition 21, Inc. Methods and compositions for the sustained release of chromium
ES2744384T3 (es) * 2007-06-13 2020-02-24 Novo Nordisk As Formulación farmacéutica que comprende un derivado de insulina
WO2009002867A2 (en) 2007-06-26 2008-12-31 Nutrition 21, Inc. Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement
PL2209800T3 (pl) * 2007-11-16 2013-12-31 Novo Nordisk As Stabilne kompozycje farmaceutyczne zawierające liraglutyd i degludec
EP2328607A1 (en) * 2008-07-16 2011-06-08 Arecor Limited Stable formulation of a therapeutic protein
EP2341940A1 (en) * 2008-07-16 2011-07-13 Arecor Limited The stabilisation of proteins
US9603904B2 (en) * 2008-10-30 2017-03-28 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
BR112013010345A2 (pt) 2010-10-27 2017-07-25 Novo Nordisk As tratamento de diabetes melitus usando as injeções de insulina administradas com intervalos de variação da injeção
WO2012119007A1 (en) 2011-03-01 2012-09-07 N21 Acquisition Holding, Llc Compositions of insulin and chromium for the treatment and prevention of diabetes, hypoglycemia and related disorders
WO2014096985A2 (en) 2012-12-19 2014-06-26 Wockhardt Limited A stable aqueous composition comprising human insulin or an analogue or derivative thereof
PL2919804T3 (pl) 2012-11-13 2018-07-31 Adocia Szybko działająca formulacja insuliny zawierająca podstawiony związek anionowy
RU2015130613A (ru) 2012-12-26 2017-01-31 Вокхардт Лимитед Фармацевтическая композиция
TWI641381B (zh) * 2013-02-04 2018-11-21 法商賽諾菲公司 胰島素類似物及／或胰島素衍生物之穩定化醫藥調配物
EP2991672A1 (en) 2013-04-30 2016-03-09 Novo Nordisk A/S Novel administration regime
WO2015084694A2 (en) * 2013-12-04 2015-06-11 Merck Sharp & Dohme Corp. Method for preparing crystalline insulin
AR102869A1 (es) 2014-12-16 2017-03-29 Lilly Co Eli Composiciones de insulina de rápida acción
JO3749B1 (ar) 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
CN109069532A (zh) 2016-02-11 2018-12-21 营养21有限责任公司 含铬组合物用于改善健康和健身
CA3034971A1 (en) * 2016-09-29 2018-04-05 Arecor Limited A pharmaceutical insulin formulation
JP6920471B2 (ja) 2017-06-01 2021-08-18 イーライ リリー アンド カンパニー 迅速に作用するインスリン組成物
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2882202A (en) * 1950-04-05 1959-04-14 Novo Terapeutisk Labor As Insulin crystal preparations and methods of producing them
US2787575A (en) * 1950-11-22 1957-04-02 Organon Zinc-glycine-insulin composition and production thereof
US2882203A (en) * 1951-06-26 1959-04-14 Novo Terapeutisk Labor As Injectable insulin preparation with protracted effect
DE1044360B (de) * 1953-08-19 1958-11-20 Roskilde Medical Company Ltd R Verfahren zur Herstellung von Zinkinsulin mit erhoehtem Zinkgehalt
DE956098C (de) * 1954-02-18 1957-01-10 Dr Dr Guenther Weitzel Verfahren zur Herstellung zinkreicher Insulin-Komplexverbindungen
US3058885A (en) * 1957-06-08 1962-10-16 Novo Terapeutisk Labor As Process for treatment of insulin crystals and for production of insulin preparationstherefrom
US3014842A (en) * 1957-08-10 1961-12-26 Novo Terapeutish Lab A S Injectable bovine insulin crystal suspensions and process of producing same
US3091573A (en) * 1958-05-12 1963-05-28 Novo Terapeutisk Labor As Quick acting insulin preparation
FR1263220A (fr) * 1958-08-01 1961-06-09 Novo Terapeutisk Labor As Procédé de production d'une préparation d'insuline à action rapide
DK116527B (da) * 1967-03-01 1970-01-19 Nordisk Insulinlab Fremgangsmåde til fremstilling af en hurtigtvirkende, holdbar, neutral opløsning af rent krystallinsk okseinsulin eller okseinsulin, der ved tilsætning af Zn er krystalliserbart i vand, eller blandinger af okseinsulin og insulin af anden oprindelse.
GB1285023A (en) * 1968-08-09 1972-08-09 Novo Terapeutisk Labor As Improvements in or relating to injectable insulin preparations
US3657425A (en) * 1969-03-12 1972-04-18 Burroughs Wellcome Co Beef insulin preparations
DE3064888D1 (en) * 1979-04-30 1983-10-27 Hoechst Ag Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization
DK80781A (da) * 1980-02-29 1981-08-30 Hospital For Sick Children Oploesninger af polypeptider
EP0102976A1 (en) * 1982-03-03 1984-03-21 Nordisk Insulinlaboratorium A process for producing an insulin preparation

Also Published As

Publication number Publication date
NO161204B (no) 1989-04-10
NO161204C (no) 1989-07-19
GR77388B (nl) 1984-09-11
IE54548B1 (en) 1989-11-08
GB2114573B (en) 1985-05-01
NL8300440A (nl) 1983-09-01
AU1113683A (en) 1983-08-11
FI830375A0 (fi) 1983-02-03
DE3303860C2 (nl) 1989-12-28
FI830375L (fi) 1983-08-06
GB8303133D0 (en) 1983-03-09
PT76195A (en) 1983-03-01
ES8500060A1 (es) 1984-10-16
ATA38983A (de) 1986-09-15
NL187269C (nl) 1991-08-01
AU549981B2 (en) 1986-02-20
ZA83742B (en) 1983-11-30
GB2114573A (en) 1983-08-24
FI78616C (fi) 1989-09-11
IE830220L (en) 1983-08-05
SE8300598D0 (sv) 1983-02-04
LU84632A1 (fr) 1983-09-08
IT8319420A0 (it) 1983-02-04
FR2521009A1 (fr) 1983-08-12
IT1178455B (it) 1987-09-09
FI78616B (fi) 1989-05-31
JPS58192818A (ja) 1983-11-10
FR2521009B1 (fr) 1987-07-17
CA1203476A (en) 1986-04-22
AT382780B (de) 1987-04-10
DE3303860A1 (de) 1983-08-18
SE8300598L (sv) 1983-08-06
BE895832A (fr) 1983-08-04
US4476118A (en) 1984-10-09
CH657530A5 (de) 1986-09-15
NO830385L (no) 1983-08-08
SE460948B (sv) 1989-12-11
ES519533A0 (es) 1984-10-16
NZ203189A (en) 1985-07-31
JPH0367056B2 (nl) 1991-10-21
PT76195B (en) 1986-01-27

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20030204