ATA38983A - Verfahren zur herstellung einer insulinloesung - Google Patents
Verfahren zur herstellung einer insulinloesungInfo
- Publication number
- ATA38983A ATA38983A AT0038983A AT38983A ATA38983A AT A38983 A ATA38983 A AT A38983A AT 0038983 A AT0038983 A AT 0038983A AT 38983 A AT38983 A AT 38983A AT A38983 A ATA38983 A AT A38983A
- Authority
- AT
- Austria
- Prior art keywords
- producing
- insulin solution
- insulin
- solution
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K13/00—Apparatus or processes specially adapted for manufacturing or adjusting assemblages of electric components
- H05K13/06—Wiring by machine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Manufacturing & Machinery (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK49182 | 1982-02-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA38983A true ATA38983A (de) | 1986-09-15 |
| AT382780B AT382780B (de) | 1987-04-10 |
Family
ID=8094159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0038983A AT382780B (de) | 1982-02-05 | 1983-02-04 | Verfahren zur herstellung einer insulinloesung |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4476118A (de) |
| JP (1) | JPS58192818A (de) |
| AT (1) | AT382780B (de) |
| AU (1) | AU549981B2 (de) |
| BE (1) | BE895832A (de) |
| CA (1) | CA1203476A (de) |
| CH (1) | CH657530A5 (de) |
| DE (1) | DE3303860A1 (de) |
| ES (1) | ES519533A0 (de) |
| FI (1) | FI78616C (de) |
| FR (1) | FR2521009B1 (de) |
| GB (1) | GB2114573B (de) |
| GR (1) | GR77388B (de) |
| IE (1) | IE54548B1 (de) |
| IT (1) | IT1178455B (de) |
| LU (1) | LU84632A1 (de) |
| NL (1) | NL187269C (de) |
| NO (1) | NO161204C (de) |
| NZ (1) | NZ203189A (de) |
| PT (1) | PT76195B (de) |
| SE (1) | SE460948B (de) |
| ZA (1) | ZA83742B (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE50502T1 (de) * | 1984-06-09 | 1990-03-15 | Hoechst Ag | Insulinzubereitungen, verfahren zu deren herstellung und deren verwendung. |
| JP2520262B2 (ja) * | 1987-08-21 | 1996-07-31 | 春幸 川原 | パツチテスト材料 |
| US4789660A (en) * | 1987-09-10 | 1988-12-06 | American Home Products Corporation | Insulin administration using methyl and propyl paraben |
| US5130298A (en) * | 1989-05-16 | 1992-07-14 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| US5534488A (en) * | 1993-08-13 | 1996-07-09 | Eli Lilly And Company | Insulin formulation |
| US5474978A (en) * | 1994-06-16 | 1995-12-12 | Eli Lilly And Company | Insulin analog formulations |
| YU18596A (sh) * | 1995-03-31 | 1998-07-10 | Eli Lilly And Company | Analogne formulacije monomernog insulina |
| AU7678196A (en) * | 1995-11-13 | 1997-06-05 | Minimed, Inc. | Methods and compositions for the delivery of monomeric proteins |
| CA2248142A1 (en) * | 1996-03-12 | 1997-09-18 | Life Technologies, Inc. | Hematopoietic cell culture nutrient supplement |
| ES2218622T3 (es) * | 1996-07-26 | 2004-11-16 | Aventis Pharma Deutschland Gmbh | Derivados de insulina con actividad de union al zinc incrementada. |
| EP1283051B1 (de) * | 1997-06-13 | 2006-06-14 | Eli Lilly And Company | Stabile Insulinformulierungen |
| PE79099A1 (es) | 1997-06-13 | 1999-08-24 | Lilly Co Eli | Formulaciones de insulina estables |
| EP1030688B1 (de) * | 1997-11-12 | 2004-09-29 | Alza Corporation | Verfahren zur dermalen verabreichung von polypeptiden |
| DE19825447A1 (de) | 1998-06-06 | 1999-12-09 | Hoechst Marion Roussel De Gmbh | Neue Insulinanaloga mit erhöhter Zinkbildung |
| CN1210058C (zh) * | 1998-10-16 | 2005-07-13 | 诺沃挪第克公司 | 用于肺送递的稳定的浓缩胰岛素制剂 |
| DE19930676B4 (de) * | 1999-07-02 | 2006-01-19 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Stabilisierung von Insulin, Insulinderivaten und/oder deren Vorläufer in komplexen Mischungen bei deren Lagerung in wäßrigen Lösungsmitteln |
| ES2266187T3 (es) * | 2000-03-24 | 2007-03-01 | Genentech, Inc. | Uso de la insulina para el tratamiento de trastornos del cartilago. |
| JP4147234B2 (ja) * | 2004-09-27 | 2008-09-10 | キヤノン株式会社 | 吐出用液体、吐出方法、カートリッジ及び吐出装置 |
| ATE496064T1 (de) | 2002-05-07 | 2011-02-15 | Novo Nordisk As | Lösliche formulierungen, die monomeres insulin und acyliertes insulin enthalten |
| US20050065066A1 (en) * | 2002-12-20 | 2005-03-24 | Kaarsholm Niels Christian | Stabilised insulin compositions |
| ATE378063T1 (de) * | 2002-12-20 | 2007-11-15 | Novo Nordisk As | Pharmazeutische zusammensetzungen mit insulin und insulin-hexamer-liganden |
| WO2004096266A1 (en) * | 2003-05-02 | 2004-11-11 | Novo Nordisk A/S | Improved physical stability of insulin formulations |
| BRPI0413276B8 (pt) * | 2003-08-05 | 2021-05-25 | Novo Nordisk As | derivado de insulina, complexo de zinco do mesmo, e, composição farmacêutica |
| EP2626368B1 (de) | 2004-07-19 | 2016-12-21 | Biocon Limited | Insulinoligomerkonjugate, Formulierungen und Verwendungen davon |
| ES2371361T3 (es) * | 2005-12-28 | 2011-12-30 | Novo Nordisk A/S | Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones. |
| US20090136538A1 (en) * | 2006-05-22 | 2009-05-28 | Jan Jezek | Stable vaccine formulation |
| GB0700523D0 (en) * | 2007-01-11 | 2007-02-21 | Insense Ltd | The Stabilisation Of Proteins |
| EP3050568B1 (de) | 2007-03-13 | 2020-12-02 | JDS Therapeutics, LLC | Verfahren und zusammensetzungen zur verzögerten freisetzung von chrom |
| EP2167032B1 (de) * | 2007-06-13 | 2019-08-07 | Novo Nordisk A/S | Pharmazeutische formulierung enthaltend ein insulinderivat |
| WO2009002867A2 (en) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement |
| PT2597103T (pt) | 2007-11-16 | 2017-02-08 | Novo Nordisk As | Composições farmacêuticas contendo insulina e um péptido insulinotrófico |
| EP2328607A1 (de) * | 2008-07-16 | 2011-06-08 | Arecor Limited | Stabile formulierung eines therapeutischen proteins |
| EP2341940A1 (de) * | 2008-07-16 | 2011-07-13 | Arecor Limited | Stabilisierung von proteinen |
| BRPI0919946A2 (pt) * | 2008-10-30 | 2016-02-16 | Novo Nordisk As | tratamento de diabetes melito usando injeções de insulina com frequência de injeção menor que diariamente |
| US9060927B2 (en) | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
| RU2013123515A (ru) | 2010-10-27 | 2014-12-10 | Ново Нордиск А/С | Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами |
| US8933022B2 (en) | 2011-03-01 | 2015-01-13 | Jds Therapeutics, Llc | Methods and compositions for the treatment and prevention Hypoglycemia and related disorders |
| CN104902922B (zh) | 2012-11-13 | 2017-12-12 | 阿道恰公司 | 包含经取代阴离子化合物的速效胰岛素制剂 |
| WO2014096985A2 (en) | 2012-12-19 | 2014-06-26 | Wockhardt Limited | A stable aqueous composition comprising human insulin or an analogue or derivative thereof |
| JP2016505601A (ja) | 2012-12-26 | 2016-02-25 | ウォックハート リミテッド | 医薬組成物 |
| TWI780236B (zh) * | 2013-02-04 | 2022-10-11 | 法商賽諾菲公司 | 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物 |
| US10137172B2 (en) | 2013-04-30 | 2018-11-27 | Novo Nordisk A/S | Administration regime |
| WO2015084694A2 (en) * | 2013-12-04 | 2015-06-11 | Merck Sharp & Dohme Corp. | Method for preparing crystalline insulin |
| AR102869A1 (es) | 2014-12-16 | 2017-03-29 | Lilly Co Eli | Composiciones de insulina de rápida acción |
| JO3749B1 (ar) | 2015-08-27 | 2021-01-31 | Lilly Co Eli | تركيبات إنسولين سريعة المفعول |
| MX2018009748A (es) | 2016-02-11 | 2019-02-07 | Nutrition 21 Llc | Composiciones que contienen cromo para mejorar la salud y el estado físico. |
| EP3518893A1 (de) * | 2016-09-29 | 2019-08-07 | Arecor Limited | Neuartige formulierungen |
| AU2018275545B2 (en) | 2017-06-01 | 2021-02-04 | Eli Lilly And Company | Rapid-acting insulin compositions |
| US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2882202A (en) * | 1950-04-05 | 1959-04-14 | Novo Terapeutisk Labor As | Insulin crystal preparations and methods of producing them |
| US2787575A (en) * | 1950-11-22 | 1957-04-02 | Organon | Zinc-glycine-insulin composition and production thereof |
| US2882203A (en) * | 1951-06-26 | 1959-04-14 | Novo Terapeutisk Labor As | Injectable insulin preparation with protracted effect |
| DE1044360B (de) * | 1953-08-19 | 1958-11-20 | Roskilde Medical Company Ltd R | Verfahren zur Herstellung von Zinkinsulin mit erhoehtem Zinkgehalt |
| DE956098C (de) * | 1954-02-18 | 1957-01-10 | Dr Dr Guenther Weitzel | Verfahren zur Herstellung zinkreicher Insulin-Komplexverbindungen |
| US3058885A (en) * | 1957-06-08 | 1962-10-16 | Novo Terapeutisk Labor As | Process for treatment of insulin crystals and for production of insulin preparationstherefrom |
| US3014842A (en) * | 1957-08-10 | 1961-12-26 | Novo Terapeutish Lab A S | Injectable bovine insulin crystal suspensions and process of producing same |
| US3091573A (en) * | 1958-05-12 | 1963-05-28 | Novo Terapeutisk Labor As | Quick acting insulin preparation |
| FR1263220A (fr) * | 1958-08-01 | 1961-06-09 | Novo Terapeutisk Labor As | Procédé de production d'une préparation d'insuline à action rapide |
| DK116527B (da) * | 1967-03-01 | 1970-01-19 | Nordisk Insulinlab | Fremgangsmåde til fremstilling af en hurtigtvirkende, holdbar, neutral opløsning af rent krystallinsk okseinsulin eller okseinsulin, der ved tilsætning af Zn er krystalliserbart i vand, eller blandinger af okseinsulin og insulin af anden oprindelse. |
| GB1285023A (en) * | 1968-08-09 | 1972-08-09 | Novo Terapeutisk Labor As | Improvements in or relating to injectable insulin preparations |
| US3657425A (en) * | 1969-03-12 | 1972-04-18 | Burroughs Wellcome Co | Beef insulin preparations |
| EP0018609B1 (de) * | 1979-04-30 | 1983-09-21 | Hoechst Aktiengesellschaft | Gegen Denaturierung beständige, wässrige Protein-Lösungen, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DK80781A (da) * | 1980-02-29 | 1981-08-30 | Hospital For Sick Children | Oploesninger af polypeptider |
| WO1983003054A1 (en) * | 1982-03-03 | 1983-09-15 | Johansen, Kristian, Betton | A proces for producing an insulin preparation |
-
1983
- 1983-02-03 FI FI830375A patent/FI78616C/fi not_active IP Right Cessation
- 1983-02-04 NL NLAANVRAGE8300440,A patent/NL187269C/xx not_active IP Right Cessation
- 1983-02-04 GB GB08303133A patent/GB2114573B/en not_active Expired
- 1983-02-04 CH CH657/83A patent/CH657530A5/de not_active IP Right Cessation
- 1983-02-04 IE IE220/83A patent/IE54548B1/en not_active IP Right Cessation
- 1983-02-04 US US06/463,730 patent/US4476118A/en not_active Expired - Lifetime
- 1983-02-04 IT IT19420/83A patent/IT1178455B/it active
- 1983-02-04 LU LU84632A patent/LU84632A1/de unknown
- 1983-02-04 JP JP58016303A patent/JPS58192818A/ja active Granted
- 1983-02-04 FR FR8301790A patent/FR2521009B1/fr not_active Expired
- 1983-02-04 AT AT0038983A patent/AT382780B/de not_active IP Right Cessation
- 1983-02-04 DE DE19833303860 patent/DE3303860A1/de active Granted
- 1983-02-04 ZA ZA83742A patent/ZA83742B/xx unknown
- 1983-02-04 PT PT76195A patent/PT76195B/pt unknown
- 1983-02-04 GR GR70416A patent/GR77388B/el unknown
- 1983-02-04 SE SE8300598A patent/SE460948B/sv not_active IP Right Cessation
- 1983-02-04 ES ES519533A patent/ES519533A0/es active Granted
- 1983-02-04 BE BE6/47775A patent/BE895832A/fr not_active IP Right Cessation
- 1983-02-04 NO NO830385A patent/NO161204C/no not_active IP Right Cessation
- 1983-02-04 CA CA000420907A patent/CA1203476A/en not_active Expired
- 1983-02-04 AU AU11136/83A patent/AU549981B2/en not_active Expired
- 1983-02-04 NZ NZ203189A patent/NZ203189A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AT382780B (de) | Verfahren zur herstellung einer insulinloesung | |
| AT385201B (de) | Verfahren zur herstellung einer antiinflammatorischen ophthalmischen loesung | |
| DE3230888A1 (de) | Verfahren zur herstellung von verbundstoffen | |
| AT383808B (de) | Verfahren zur herstellung von penemen | |
| ATA148982A (de) | Verfahren zur herstellung einer analgetisch wirkenden zusammensetzung | |
| ATA423783A (de) | Verfahren zur herstellung von beta-hydroxybuttersaeurederivaten | |
| AT379831B (de) | Verfahren zur herstellung von kristallen | |
| AT374827B (de) | Verfahren zur herstellung von cholesterase | |
| AT389512B (de) | Verfahren zur herstellung von 3-chlormethylchinuclidin | |
| DE3650051D1 (de) | Verfahren zur Herstellung einer Roentgenlinse. | |
| AT367436B (de) | Verfahren zur herstellung von copolymerisaten | |
| AT379161B (de) | Verfahren zur herstellung von elastomer-duromer-verbundteilen | |
| AT376879B (de) | Verfahren zur herstellung einer injektionsloesung | |
| AT387770B (de) | Verbessertes verfahren zur herstellung von trichlorisocyanursaeure | |
| AT380686B (de) | Verfahren zur herstellung von buspiron | |
| DE3667276D1 (de) | Verfahren zur herstellung einer azidosulfonylbenzoesaeure. | |
| AT380480B (de) | Verfahren zur herstellung von anthracyclinglykosiden | |
| AT375328B (de) | Verfahren zur herstellung von sintermagnesia | |
| AT388374B (de) | Verfahren zur herstellung von n-sulfonylaryloxybenzamiden | |
| ATA201283A (de) | Verfahren zur herstellung von carboxyalkyldipeptiden | |
| ATA319282A (de) | Verfahren zur herstellung von reinem 3-amino-crotonitril | |
| ATA110780A (de) | Verfahren zur herstellung von o-trimethylsilyl- -cellulosen | |
| ATA328581A (de) | Verfahren zur herstellung von 1-phenoxy-3-amino- 2-propanolen | |
| ATA535281A (de) | Verfahren zur herstellung von phenoxyisobutters|ureestern | |
| ATA263781A (de) | Verfahren zur herstellung von beta-amidoethyl-ether-derivaten |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |