AU3534193A - Cyclic peptide antifungal agents and process for preparation thereof - Google Patents

Cyclic peptide antifungal agents and process for preparation thereof

Info

Publication number
AU3534193A
AU3534193A AU35341/93A AU3534193A AU3534193A AU 3534193 A AU3534193 A AU 3534193A AU 35341/93 A AU35341/93 A AU 35341/93A AU 3534193 A AU3534193 A AU 3534193A AU 3534193 A AU3534193 A AU 3534193A
Authority
AU
Australia
Prior art keywords
hydrogen
preparation
antifungal agents
cyclic peptide
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35341/93A
Other languages
English (en)
Inventor
Frederick Joseph Burkhardt
Manuel Debono
Jeffrey Scott Nissen
William Wilson Turner Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU3534193A publication Critical patent/AU3534193A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/66—Gramicidins S, C; Tyrocidins A, B, C; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
AU35341/93A 1992-03-19 1993-03-19 Cyclic peptide antifungal agents and process for preparation thereof Abandoned AU3534193A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85411792A 1992-03-19 1992-03-19
US99239092A 1992-12-16 1992-12-16
US992390 1992-12-16
US854117 1992-12-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU65529/96A Division AU689391B2 (en) 1992-03-19 1996-09-09 Cyclic peptide antifungal agents and process for preparation thereof

Publications (1)

Publication Number Publication Date
AU3534193A true AU3534193A (en) 1993-09-23

Family

ID=27127211

Family Applications (2)

Application Number Title Priority Date Filing Date
AU35341/93A Abandoned AU3534193A (en) 1992-03-19 1993-03-19 Cyclic peptide antifungal agents and process for preparation thereof
AU65529/96A Expired AU689391B2 (en) 1992-03-19 1996-09-09 Cyclic peptide antifungal agents and process for preparation thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU65529/96A Expired AU689391B2 (en) 1992-03-19 1996-09-09 Cyclic peptide antifungal agents and process for preparation thereof

Country Status (25)

Country Link
EP (1) EP0561639B1 (enExample)
JP (3) JP3519754B2 (enExample)
KR (1) KR100256036B1 (enExample)
CN (1) CN1036715C (enExample)
AT (1) ATE217635T1 (enExample)
AU (2) AU3534193A (enExample)
BR (1) BR9301232A (enExample)
CA (1) CA2091663C (enExample)
CZ (1) CZ288974B6 (enExample)
DE (2) DE122008000006I2 (enExample)
DK (1) DK0561639T3 (enExample)
ES (1) ES2174843T3 (enExample)
FI (1) FI118768B (enExample)
HU (2) HU225783B1 (enExample)
IL (3) IL122315A (enExample)
LU (1) LU91406I2 (enExample)
MX (1) MX9301457A (enExample)
MY (1) MY136593A (enExample)
NL (1) NL300334I2 (enExample)
NO (1) NO930948L (enExample)
NZ (3) NZ512085A (enExample)
PT (1) PT561639E (enExample)
RU (1) RU2129562C1 (enExample)
TW (1) TW264477B (enExample)
YU (1) YU49108B (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430018A (en) * 1991-10-17 1995-07-04 Merck & Co., Inc. Cyclohexapeptide with basic nitrogen containing alkylamide groups
IL122315A (en) * 1992-03-19 2002-03-10 Lilly Co Eli Cyclic peptides and antifungal pharmaceutical compositions containing them
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
AU674233B2 (en) * 1993-05-04 1996-12-12 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
AU7874494A (en) * 1993-09-22 1995-04-10 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
EP0781141B1 (en) * 1994-09-16 2002-09-04 Merck & Co. Inc. Aza cyclohexapeptide compounds
US5514651A (en) * 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
HU228151B1 (en) * 1994-10-07 2012-12-28 Astellas Pharma Inc Cyclic hexapeptides
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
PT805685E (pt) * 1995-01-26 2002-02-28 Merck & Co Inc Novos ciclo-hexapeptideos anti-fungicos
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
EP0881907A4 (en) * 1996-02-01 2000-05-10 Lilly Co Eli FUNGICIDES IN THE FORM OF CYCLIC PEPTIDES
US5693611A (en) * 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
JPH09227422A (ja) * 1996-02-12 1997-09-02 Rolic Ag シクロペンチル誘導体
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
UA72200C2 (uk) * 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
AU2003200556B2 (en) * 1997-12-10 2005-12-01 Novexel Echinocandin derivative and their preparation method
AUPP172898A0 (en) * 1998-02-09 1998-03-05 Fujisawa Pharmaceutical Co., Ltd. New compound
EP1064299A1 (en) * 1998-03-16 2001-01-03 Fujisawa Pharmaceutical Co., Ltd. Cyclohexapeptide wf14573 or its salt, production thereof and use thereof
EP1107981B1 (en) 1998-08-20 2005-01-26 Eli Lilly & Company Synthesis of ring-modified cyclic peptide analogs
ATE338059T1 (de) 1998-12-09 2006-09-15 Lilly Co Eli Reinigung von echinocandin cyclopeptiden
DE19907904A1 (de) 1999-02-24 2000-08-31 Clariant Gmbh Verfahren zur Herstellung von [1,1':4',1"]-Terphenylverbindungen
DK1582204T3 (da) 1999-03-03 2013-11-04 Lilly Co Eli Echinocandin-farmaceutiske formuleringer, der indeholder miceldannende overfladeaktive stoffer
CN1345230A (zh) 1999-03-03 2002-04-17 伊莱利利公司 口服ecb药物制剂和药物组合物的制备方法
DK1155034T3 (da) 1999-03-03 2007-01-08 Lilly Co Eli Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte
AU772633B2 (en) 1999-03-03 2004-05-06 Eli Lilly And Company Echinocandin/carbohydrate complexes
CA2400640A1 (en) * 2000-02-18 2001-08-23 Meiji Seika Kaisha, Ltd. Phenoxyalkylamine derivatives useful as opioid .delta. receptor ligands
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
MXPA05011536A (es) * 2003-04-30 2006-01-23 Inst For Pharm Discovery Inc Acidos carboxilicos substituidos con fenilo como inhibidores de la proteina tirosina fosfatasa-1b.
KR101551207B1 (ko) * 2008-09-04 2015-09-08 롬엔드하스전자재료코리아유한회사 신규한 유기 발광 화합물 및 이를 발광재료로서 채용하고 있는 유기 발광 소자
CN102464704B (zh) * 2010-11-05 2013-12-11 上海医药工业研究院 一种化合物及其制备方法和用途
SI3677252T1 (sl) * 2012-03-19 2024-02-29 Cidara Therapeutics, Inc. Sheme odmerjanja za spojine iz razreda ehinokandinov
PL3058958T3 (pl) 2015-02-23 2019-02-28 Selectchemie Ag Kompozycja anidulafunginy
JP6866583B2 (ja) * 2016-07-05 2021-04-28 Dic株式会社 液晶化合物
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE886576A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
BE886575A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) * 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
IL122315A (en) * 1992-03-19 2002-03-10 Lilly Co Eli Cyclic peptides and antifungal pharmaceutical compositions containing them

Also Published As

Publication number Publication date
RU2129562C1 (ru) 1999-04-27
NZ299314A (en) 2001-09-28
ATE217635T1 (de) 2002-06-15
NO930948D0 (no) 1993-03-16
KR930019694A (ko) 1993-10-18
IL122315A0 (en) 1998-04-05
KR100256036B1 (ko) 2000-05-01
DE69331922T2 (de) 2002-08-29
JP2002226500A (ja) 2002-08-14
CZ288974B6 (cs) 2001-10-17
EP0561639A1 (en) 1993-09-22
CN1080926A (zh) 1994-01-19
HU9300785D0 (en) 1993-06-28
NZ512085A (en) 2003-08-29
PT561639E (pt) 2002-10-31
YU18593A (sh) 1996-10-09
HU225783B1 (en) 2007-09-28
ES2174843T3 (es) 2002-11-16
FI931202A0 (fi) 1993-03-18
CN1036715C (zh) 1997-12-17
YU49108B (sh) 2004-03-12
DE122008000006I2 (de) 2011-07-21
CZ41693A3 (en) 1994-07-13
JP3520071B2 (ja) 2004-04-19
CA2091663A1 (en) 1993-09-20
IL122315A (en) 2002-03-10
FI118768B (fi) 2008-03-14
DE122008000006I1 (de) 2008-04-17
MX9301457A (es) 1994-02-28
NO930948L (no) 1993-09-20
AU6552996A (en) 1996-12-05
NZ247149A (en) 1996-10-28
LU91406I2 (fr) 2008-03-10
AU689391B2 (en) 1998-03-26
IL105048A (en) 2001-06-14
NL300334I1 (nl) 2008-03-03
NL300334I2 (nl) 2008-05-01
DK0561639T3 (da) 2002-06-17
EP0561639B1 (en) 2002-05-15
DE69331922D1 (de) 2002-06-20
JP3519754B2 (ja) 2004-04-19
FI931202L (fi) 1993-09-20
JP2004115540A (ja) 2004-04-15
HUT63637A (en) 1993-09-28
JPH0656892A (ja) 1994-03-01
HU211562A9 (en) 1995-12-28
BR9301232A (pt) 1993-09-21
TW264477B (enExample) 1995-12-01
IL105048A0 (en) 1993-07-08
MY136593A (en) 2008-10-31
CA2091663C (en) 2007-10-30

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