BR0008713A - Processos para preparar formulações ecomposições farmacêuticas orais com ecb - Google Patents

Processos para preparar formulações ecomposições farmacêuticas orais com ecb

Info

Publication number
BR0008713A
BR0008713A BR0008713-0A BR0008713A BR0008713A BR 0008713 A BR0008713 A BR 0008713A BR 0008713 A BR0008713 A BR 0008713A BR 0008713 A BR0008713 A BR 0008713A
Authority
BR
Brazil
Prior art keywords
ecb
processes
echinocandin
compositions
pharmaceutical formulations
Prior art date
Application number
BR0008713-0A
Other languages
English (en)
Inventor
John Richard Schwier
Jerry Taylor
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR0008713A publication Critical patent/BR0008713A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: "PROCESSOS PARA PREPARARFORMULAçõES E COMPOSIçõES FARMACêUTICAS ORAISCOM ECB". é descrito um processo de pulverização de leito fluidoonde um ou mais carboidratos são incorporados em umaformulação de echinocandin para prover uma melhoria significativada estabilidade térmica. O carboidrato é solubilizado com umcomposto echinocandin ou complexo echinocandin/ carboidratoem (um) solvente (s) para formar uma solução farmacêutica que épulverizada na superfície de um diluente ou portador granular.Alternativamente, um agente de granulação é adicionado àsolução farmacêutica, que é, então pulverizada na superfície deum diluente ou portador não granular. As formulações oraisgranulares resultantes e medicamentos derivados das mesmas sãotambém descritos.
BR0008713-0A 1999-03-03 2000-03-02 Processos para preparar formulações ecomposições farmacêuticas orais com ecb BR0008713A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12269399P 1999-03-03 1999-03-03
PCT/US2000/005547 WO2000051567A1 (en) 1999-03-03 2000-03-02 Processes for making pharmaceutical oral ecb formulations and compositions

Publications (1)

Publication Number Publication Date
BR0008713A true BR0008713A (pt) 2001-12-26

Family

ID=22404178

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008713-0A BR0008713A (pt) 1999-03-03 2000-03-02 Processos para preparar formulações ecomposições farmacêuticas orais com ecb

Country Status (12)

Country Link
US (1) US6821951B2 (pt)
EP (1) EP1156784A1 (pt)
JP (1) JP2002538097A (pt)
KR (1) KR20010112302A (pt)
CN (1) CN1345230A (pt)
AU (1) AU771727B2 (pt)
BR (1) BR0008713A (pt)
CA (1) CA2362482A1 (pt)
HK (1) HK1040369A1 (pt)
IL (1) IL145188A0 (pt)
WO (1) WO2000051567A1 (pt)
ZA (1) ZA200108001B (pt)

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JP2003511345A (ja) 1998-12-09 2003-03-25 イーライ リリー アンド カンパニー Ｅｃｈｉｎｏｃａｎｄｉｎシクロペプチド化合物の精製
ATE294571T1 (de) * 1999-03-03 2005-05-15 Lilly Co Eli Echinocandin pharmazeutische zusammensetzungen
CN1345333A (zh) 1999-03-03 2002-04-17 伊莱利利公司 棘白菌素/糖类复合物
CA2362482A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
DK1155034T3 (da) 1999-03-03 2007-01-08 Lilly Co Eli Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte
TWI233805B (en) 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
AUPR272901A0 (en) * 2001-01-25 2001-02-22 Gainful Plan Limited Method of preparing biological materials and preparations produced using same
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US20050233074A1 (en) * 2002-08-14 2005-10-20 Dalziel Sean M Solid flowable powder with high liquid loading
CA2490601C (en) * 2003-12-29 2006-05-02 Ferring B.V. Method for preparing solid dosage form of desmopressin
HUE036778T2 (hu) 2011-03-03 2018-07-30 Cidara Therapeutics Inc Gombaellenes szerek és alkalmazásuk
SI2827710T1 (sl) 2012-03-19 2020-04-30 Cidara Therapeutics, Inc. Režimi odmerjanja za spojine razreda ehinokandin
CN103330932B (zh) * 2013-04-26 2015-12-23 江苏豪森药业股份有限公司 一种米卡芬净或其盐的药物组合物
EP3399995A4 (en) 2016-01-08 2019-08-21 Cidara Therapeutics, Inc. METHODS FOR PREVENTING AND TREATING PNEUMOCYSTIS INFECTIONS
MA43825A (fr) 2016-03-16 2021-04-07 Cidara Therapeutics Inc Schémas posologiques pour le traitement d'infections fongiques
WO2019014333A1 (en) 2017-07-12 2019-01-17 Cidara Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS
CN109574811B (zh) * 2018-11-22 2021-12-24 中山大学 一种阿尼芬净侧链中间体对戊氧基三联苯甲酸的制备方法

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Also Published As

Publication number Publication date
WO2000051567A8 (en) 2002-05-30
AU3393400A (en) 2000-09-21
CN1345230A (zh) 2002-04-17
HK1040369A1 (zh) 2002-06-07
ZA200108001B (en) 2003-06-25
US6821951B2 (en) 2004-11-23
CA2362482A1 (en) 2000-09-08
AU771727B2 (en) 2004-04-01
WO2000051567A1 (en) 2000-09-08
IL145188A0 (en) 2002-06-30
EP1156784A1 (en) 2001-11-28
JP2002538097A (ja) 2002-11-12
KR20010112302A (ko) 2001-12-20
US20020151474A1 (en) 2002-10-17

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.