DE69917467D1 - Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden - Google Patents

Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden

Info

Publication number
DE69917467D1
DE69917467D1 DE69917467T DE69917467T DE69917467D1 DE 69917467 D1 DE69917467 D1 DE 69917467D1 DE 69917467 T DE69917467 T DE 69917467T DE 69917467 T DE69917467 T DE 69917467T DE 69917467 D1 DE69917467 D1 DE 69917467D1
Authority
DE
Germany
Prior art keywords
cis
complexes
diol cyclic
boronate
reversible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69917467T
Other languages
English (en)
Inventor
Allen Moser
Clayton Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69917467D1 publication Critical patent/DE69917467D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69917467T 1998-08-28 1999-08-18 Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden Expired - Lifetime DE69917467D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9826798P 1998-08-28 1998-08-28
PCT/US1999/019066 WO2000012540A1 (en) 1998-08-28 1999-08-18 Reversible boronate complexes of 1,2-cis-diol cyclic-peptides

Publications (1)

Publication Number Publication Date
DE69917467D1 true DE69917467D1 (de) 2004-06-24

Family

ID=22268490

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69917467T Expired - Lifetime DE69917467D1 (de) 1998-08-28 1999-08-18 Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden

Country Status (6)

Country Link
EP (1) EP1107982B1 (de)
AT (1) ATE267210T1 (de)
AU (2) AU763351B2 (de)
CA (1) CA2340647A1 (de)
DE (1) DE69917467D1 (de)
WO (1) WO2000012540A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
JP2002528388A (ja) 1998-08-20 2002-09-03 イーライ リリー アンド カンパニー 環改変された環状ペプチドアナログ
DK1137663T3 (da) 1998-12-09 2007-01-08 Lilly Co Eli Oprensning af Echinocandin-cyclopeptidforbindelser
EP1156782B1 (de) 1999-03-03 2005-05-04 Eli Lilly And Company Echinocandin pharmazeutische zusammensetzungen
ES2204548T3 (es) 1999-03-03 2004-05-01 Eli Lilly And Company Complejos de equinocandina/carbohidrato.
IL145188A0 (en) 1999-03-03 2002-06-30 Lilly Co Eli Processes for making pharmaceutical oral ecb formulations and compositions
JP4063497B2 (ja) 1999-03-03 2008-03-19 イーライ リリー アンド カンパニー エキノカンジンアンモニウム塩結晶の形成およびアニオン交換
AR035808A1 (es) * 2001-04-12 2004-07-14 Merck & Co Inc Proceso de deshidratacion capaz de minimizar la epimerizacion de un grupo hidroxilo por ciertas equinocandinas
US7399645B2 (en) 2004-05-12 2008-07-15 Applera Corporation Constrained cis-diol-borate bioconjugation system
CN102421790A (zh) * 2009-05-07 2012-04-18 帝斯曼知识产权资产管理有限公司 制备环肽的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631364A (en) * 1994-03-31 1997-05-20 Axis Biochemicals Asa Labelled boronic acid derivatives
HRP970318B1 (en) * 1996-06-14 2002-06-30 Merck & Co Inc A process for preparing certain aza cyclohexapeptides

Also Published As

Publication number Publication date
EP1107982A1 (de) 2001-06-20
AU5683499A (en) 2000-03-21
EP1107982B1 (de) 2004-05-19
ATE267210T1 (de) 2004-06-15
WO2000012540A1 (en) 2000-03-09
CA2340647A1 (en) 2000-03-09
AU763351B2 (en) 2003-07-17
AU2003252851A1 (en) 2003-11-06

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Legal Events

Date Code Title Description
8332 No legal effect for de