FI934680A0 - Arylmorfolin, framstaellning och anvaending - Google Patents

Arylmorfolin, framstaellning och anvaending

Info

Publication number
FI934680A0
FI934680A0 FI934680A FI934680A FI934680A0 FI 934680 A0 FI934680 A0 FI 934680A0 FI 934680 A FI934680 A FI 934680A FI 934680 A FI934680 A FI 934680A FI 934680 A0 FI934680 A0 FI 934680A0
Authority
FI
Finland
Prior art keywords
arylmorfolin
anvaending
framstaellning och
human
framstaellning
Prior art date
Application number
FI934680A
Other languages
English (en)
Other versions
FI934680A (fi
Inventor
Nariman Bomanshaw Mehta
Grady Evan Boswell
James Leroy Kelley
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI934680A0 publication Critical patent/FI934680A0/fi
Publication of FI934680A publication Critical patent/FI934680A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI934680A 1991-04-23 1993-10-22 Arylmorfolin, framstaellning och anvaending FI934680A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919108629A GB9108629D0 (en) 1991-04-23 1991-04-23 Heterocyclic pharmaceutical compounds,preparation and use
PCT/GB1992/000733 WO1992018489A1 (en) 1991-04-23 1992-04-22 Arylmorpholine, preparation and use

Publications (2)

Publication Number Publication Date
FI934680A0 true FI934680A0 (fi) 1993-10-22
FI934680A FI934680A (fi) 1993-10-22

Family

ID=10693740

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934680A FI934680A (fi) 1991-04-23 1993-10-22 Arylmorfolin, framstaellning och anvaending

Country Status (17)

Country Link
US (2) US5648347A (fi)
EP (1) EP0583271B1 (fi)
JP (1) JP3130040B2 (fi)
AT (1) ATE173252T1 (fi)
AU (1) AU668863B2 (fi)
CA (1) CA2108967C (fi)
DE (1) DE69227583T2 (fi)
DK (1) DK0583271T3 (fi)
ES (1) ES2124256T3 (fi)
FI (1) FI934680A (fi)
GB (1) GB9108629D0 (fi)
HU (1) HU219458B (fi)
IE (1) IE921260A1 (fi)
NZ (1) NZ242421A (fi)
PT (1) PT100415B (fi)
WO (1) WO1992018489A1 (fi)
ZA (1) ZA922910B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
US7098206B2 (en) 1998-01-21 2006-08-29 Smithkline Beecham Corporation Pharmaceutically active morpholinol
EE04452B1 (et) 1998-01-21 2005-04-15 Glaxo Group Limited Farmatseutiliselt aktiivne morfolinool ja selle kasutamine
US6998400B2 (en) 1998-01-22 2006-02-14 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6855820B2 (en) 1999-01-20 2005-02-15 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6734213B2 (en) 1999-01-20 2004-05-11 Smithkline Beecham Corporation Pharmaceutically active morpholinol
FR2796069B3 (fr) * 1999-07-09 2001-08-24 Sanofi Synthelabo Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes
GB0228787D0 (en) * 2002-12-10 2003-01-15 Pfizer Ltd Morpholine dopamine agonists
US7323462B2 (en) 2002-12-10 2008-01-29 Pfizer Inc. Morpholine dopamine agonists
WO2004052372A1 (en) * 2002-12-10 2004-06-24 Pfizer Limited Morpholine derivatives for use as dopamine agonists in the treatment of i.a. sexual dysfunction
AU2011255276B2 (en) * 2010-05-21 2016-09-22 Research Triangle Institute Phenylmorpholines and analogues thereof
ES2546492T3 (es) 2010-05-21 2015-09-24 Research Triangle Institute Derivados de 1-fenilmorfolina como análogos de hidroxibupropion para tratar drogodependencia
CN105949142B (zh) * 2016-05-21 2018-03-27 南华大学 具有抗抑郁活性的单一手性化合物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2997469A (en) * 1961-08-22 Preparation of substituted
GB851311A (en) * 1958-04-02 1960-10-12 Geigy Ag J R Morpholine compounds and their production
US3117967A (en) * 1962-04-02 1964-01-14 Smith Kline French Lab 2-biphenylyl-2-hydroxy-morpholinium halides
GB1336732A (en) * 1970-10-28 1973-11-07 Istituto Gentili Spa Pisa Diethanolamine derivatives
IE50355B1 (en) * 1979-10-20 1986-04-02 Wyeth John & Brother Ltd Morpholine derivatives
FR2517305B1 (fr) * 1981-12-01 1985-10-25 Lafon Labor Nouveaux derives de 2-phenyl-morpholine et leur utilisation en therapeutique
FR2553411B1 (fr) * 1983-10-14 1986-08-01 Lafon Labor Derives de 2-halogenophenyl-morpholine, procede de preparation et utilisation en therapeutique
FR2553410B1 (fr) * 1983-10-14 1986-05-16 Lafon Labor Nouveaux derives de 2-tolyl-morpholine utiles en therapeutique
FR2553413B1 (fr) * 1983-10-17 1986-03-21 Lafon Labor Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique
GB8417170D0 (en) * 1984-07-05 1984-08-08 Wellcome Found Heterocyclic pharmaceutical compounds
US4803200A (en) * 1987-10-02 1989-02-07 A. H. Robins Company, Incorporated Substituted dialkanolamines, sulfur analogs and condensed 1,4-oxazine derivatives thereof in viral disease treatment
GB8924528D0 (en) * 1989-10-31 1989-12-20 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use

Also Published As

Publication number Publication date
AU668863B2 (en) 1996-05-23
ZA922910B (en) 1994-01-24
JPH06506675A (ja) 1994-07-28
HU9303000D0 (en) 1994-01-28
DK0583271T3 (da) 1999-07-26
IE921260A1 (en) 1992-11-04
ATE173252T1 (de) 1998-11-15
JP3130040B2 (ja) 2001-01-31
PT100415A (pt) 1993-06-30
HUT70531A (en) 1995-10-30
FI934680A (fi) 1993-10-22
ES2124256T3 (es) 1999-02-01
GB9108629D0 (en) 1991-06-12
US5760224A (en) 1998-06-02
HU219458B (hu) 2001-04-28
DE69227583T2 (de) 1999-04-01
PT100415B (pt) 1999-08-31
WO1992018489A1 (en) 1992-10-29
EP0583271A1 (en) 1994-02-23
CA2108967C (en) 2002-10-08
DE69227583D1 (de) 1998-12-17
EP0583271B1 (en) 1998-11-11
CA2108967A1 (en) 1992-10-24
US5648347A (en) 1997-07-15
AU1575392A (en) 1992-11-17
NZ242421A (en) 1994-10-26

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Legal Events

Date Code Title Description
MA Patent expired