EA199700136A1 - Способы ингибирования экзогенных эстрогенов - Google Patents

Способы ингибирования экзогенных эстрогенов

Info

Publication number
EA199700136A1
EA199700136A1 EA199700136A EA199700136A EA199700136A1 EA 199700136 A1 EA199700136 A1 EA 199700136A1 EA 199700136 A EA199700136 A EA 199700136A EA 199700136 A EA199700136 A EA 199700136A EA 199700136 A1 EA199700136 A1 EA 199700136A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
inhibiting
exogenous estrogens
estrogens
inhibiting exogenous
Prior art date
Application number
EA199700136A
Other languages
English (en)
Inventor
Генри У. Бриант
Джеффри А. Додж
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA199700136A1 publication Critical patent/EA199700136A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Заявлен способ ингибирования влияния экзогенных эстрогенов, включающий введение человеку или другому животному, нуждающемуся в этом, эффективного количества соединения, имеющего формулу Iгде Rи Rпредставляют собой, независимо друг от друга, водород, -CH,илигде Ar представляет собой необязательно замещенный фенил; Rвыбран из группы, включающей пирролидин, гексаметиленимино и пиперидино; или его фармацевтически приемлемой соли либо сольвата.
EA199700136A 1995-01-25 1997-08-22 Способы ингибирования экзогенных эстрогенов EA199700136A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/378,229 US5521214A (en) 1995-01-25 1995-01-25 Methods of inhibiting environmental estrogens
PCT/US1996/000902 WO1996022771A1 (en) 1995-01-25 1996-01-22 Methods of inhibiting environmental estrogens

Publications (1)

Publication Number Publication Date
EA199700136A1 true EA199700136A1 (ru) 1997-12-30

Family

ID=23492278

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199700136A EA199700136A1 (ru) 1995-01-25 1997-08-22 Способы ингибирования экзогенных эстрогенов

Country Status (13)

Country Link
US (1) US5521214A (ru)
EP (1) EP0806950A4 (ru)
JP (1) JPH10512886A (ru)
KR (1) KR19980701589A (ru)
CN (1) CN1169116A (ru)
AU (1) AU699678B2 (ru)
CA (1) CA2210940A1 (ru)
CZ (1) CZ233797A3 (ru)
EA (1) EA199700136A1 (ru)
FI (1) FI973095A (ru)
HU (1) HUP9800550A3 (ru)
NO (1) NO973367L (ru)
WO (1) WO1996022771A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624800D0 (en) * 1996-11-29 1997-01-15 Lilly Co Eli Methods of preventing breast cancer
CA2219377A1 (en) * 1996-10-30 1998-04-30 Eli Lilly And Company Improvements in or relating to the prophylaxis of breast cancer
US5760030A (en) * 1997-06-30 1998-06-02 Eli Lilly And Company Benzothiophene compounds and methods of use
AU777770C (en) 1999-05-04 2005-11-10 Strakan International Limited Androgen glycosides and androgenic activity thereof
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
KR100334130B1 (ko) * 2000-02-18 2002-04-26 정명식 에스트로겐 유사물질의 생물학적 분석방법
KR100368936B1 (ko) * 2000-10-04 2003-01-24 주식회사 대웅 우루소데옥시콜린산을 함유한 환경호르몬 독성의 예방 및치료제
JP4270540B2 (ja) * 2000-11-28 2009-06-03 田辺三菱製薬株式会社 蓄積性塩素含有化合物の排泄促進剤
US7720727B2 (en) * 2001-03-01 2010-05-18 Fisher-Rosemount Systems, Inc. Economic calculations in process control system
PL3820874T3 (pl) * 2018-07-12 2023-02-06 Eli Lilly And Company Selektywne środki degradujące receptor estrogenowy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
US5451590A (en) * 1993-12-21 1995-09-19 Eli Lilly & Co. Methods of inhibiting sexual precocity
US5593987A (en) * 1993-12-21 1997-01-14 Eli Lilly And Company Methods of inhibiting breast disorders

Also Published As

Publication number Publication date
MX9705537A (es) 1997-10-31
WO1996022771A1 (en) 1996-08-01
NO973367D0 (no) 1997-07-21
HUP9800550A3 (en) 1999-10-28
KR19980701589A (ko) 1998-05-15
EP0806950A4 (en) 1999-01-07
FI973095A0 (fi) 1997-07-23
CA2210940A1 (en) 1996-08-01
HUP9800550A2 (hu) 1998-12-28
NO973367L (no) 1997-07-21
CZ233797A3 (cs) 1998-02-18
AU4764996A (en) 1996-08-14
CN1169116A (zh) 1997-12-31
FI973095A (fi) 1997-07-24
EP0806950A1 (en) 1997-11-19
US5521214A (en) 1996-05-28
JPH10512886A (ja) 1998-12-08
AU699678B2 (en) 1998-12-10

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