MX9701360A - Metodos para la inhibicion de la desmielinizacion y las enfermedades de la dismielinizacion. - Google Patents
Metodos para la inhibicion de la desmielinizacion y las enfermedades de la dismielinizacion.Info
- Publication number
- MX9701360A MX9701360A MX9701360A MX9701360A MX9701360A MX 9701360 A MX9701360 A MX 9701360A MX 9701360 A MX9701360 A MX 9701360A MX 9701360 A MX9701360 A MX 9701360A MX 9701360 A MX9701360 A MX 9701360A
- Authority
- MX
- Mexico
- Prior art keywords
- demyelinating
- inhibiting
- methods
- dysmyelinating diseases
- dysmyelinating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se refiere al uso de un compuesto que tiene la formula (I) en donde R1 y R2 son, en forma independiente, hidrogeno, -CH3, (a) o (b) en donde Ar es fenilo substituido opcionalmente; R2 se selecciona del grupo que consiste de pirrolidina, haxametilenimino, y piperidino; o una sal o solvato, farmacéuticamente aceptable del mismo, para la preparacion de un medicamento para inhibir las enfermedades de desmielizacion o dismielinizacion o sus síntomas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/294,238 US5434166A (en) | 1994-08-22 | 1994-08-22 | Methods of inhibiting demyelinating and desmyelinating diseases |
PCT/US1995/010581 WO1996005823A1 (en) | 1994-08-22 | 1995-08-21 | Methods of inhibiting demyelinating and dysmyelinating diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9701360A true MX9701360A (es) | 1997-05-31 |
Family
ID=23132498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9701360A MX9701360A (es) | 1994-08-22 | 1995-08-21 | Metodos para la inhibicion de la desmielinizacion y las enfermedades de la dismielinizacion. |
Country Status (10)
Country | Link |
---|---|
US (2) | US5434166A (es) |
EP (1) | EP0769943A4 (es) |
JP (1) | JPH10505823A (es) |
AU (1) | AU3368595A (es) |
BR (1) | BR9508732A (es) |
CA (1) | CA2198114A1 (es) |
IL (1) | IL115015A0 (es) |
MX (1) | MX9701360A (es) |
WO (1) | WO1996005823A1 (es) |
ZA (1) | ZA956993B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US5770609A (en) | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6395494B1 (en) | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6417198B1 (en) | 1993-12-21 | 2002-07-09 | Eli Lilly And Company | Methods of inhibiting CNS problems in post-menopausal women |
CA2223595C (en) | 1995-06-07 | 2008-08-05 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
IL120266A (en) | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
TW442286B (en) * | 1996-02-28 | 2001-06-23 | Pfizer | New therapeutic uses of estrogen agonists |
ZA982877B (en) * | 1997-04-09 | 1999-10-04 | Lilly Co Eli | Treatment of central nervous system disorders with selective estrogen receptor modulators. |
US6117911A (en) * | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
US5990129A (en) * | 1997-09-23 | 1999-11-23 | Eli Lilly And Company | Methods for regulating trkA expression |
US6355677B1 (en) | 1998-09-28 | 2002-03-12 | The Johns Hopkins University | Adrenoleukodystrophy treatments and drug screening |
HUP0200871A3 (en) | 1999-05-04 | 2004-04-28 | Strakan Int Ltd | Androgen glycosides and androgenic activity thereof |
US6458838B1 (en) | 1999-09-28 | 2002-10-01 | Johns Hopkins University | Adrenoleukodystrophy treatments |
US6329564B1 (en) * | 1999-11-29 | 2001-12-11 | Michael Lebner | Bandage for wound or incision closure |
CN1723013A (zh) * | 2003-01-06 | 2006-01-18 | 惠氏公司 | 雌激素受体α调节剂在治疗多发性硬化症中的用途 |
WO2011011781A1 (en) | 2009-07-24 | 2011-01-27 | Baylor College Of Medicine | Methods of modulation of branched chain acids and uses thereof |
JP2019524805A (ja) * | 2016-08-12 | 2019-09-05 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California | 髄鞘再生療法 |
WO2019006164A1 (en) | 2017-06-28 | 2019-01-03 | Baylor College Of Medicine | POLYTHERAPY TO TREAT UREA CYCLE DISORDERS |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US4380635A (en) * | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
US5075321A (en) * | 1987-03-24 | 1991-12-24 | University Of Pennsylvania | Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes |
US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
US5521198A (en) * | 1993-12-21 | 1996-05-28 | Eli Lilly And Company | Methods of inhibiting autoimmune diseases |
US5708009A (en) * | 1993-12-21 | 1998-01-13 | Eli Lilly And Company | Methods of inhibiting myeloperoxidase activity |
US5552415A (en) * | 1993-12-21 | 1996-09-03 | Eli Lilly And Company | Method of inhibiting Alzheimer's Disease |
-
1994
- 1994-08-22 US US08/294,238 patent/US5434166A/en not_active Expired - Fee Related
-
1995
- 1995-02-02 US US08/382,544 patent/US5530010A/en not_active Expired - Fee Related
- 1995-08-21 MX MX9701360A patent/MX9701360A/es unknown
- 1995-08-21 JP JP8508231A patent/JPH10505823A/ja not_active Withdrawn
- 1995-08-21 BR BR9508732A patent/BR9508732A/pt not_active Application Discontinuation
- 1995-08-21 AU AU33685/95A patent/AU3368595A/en not_active Abandoned
- 1995-08-21 CA CA002198114A patent/CA2198114A1/en not_active Abandoned
- 1995-08-21 IL IL11501595A patent/IL115015A0/xx unknown
- 1995-08-21 ZA ZA9506993A patent/ZA956993B/xx unknown
- 1995-08-21 EP EP95930224A patent/EP0769943A4/en not_active Withdrawn
- 1995-08-21 WO PCT/US1995/010581 patent/WO1996005823A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL115015A0 (en) | 1995-12-08 |
EP0769943A1 (en) | 1997-05-02 |
BR9508732A (pt) | 1997-11-11 |
US5434166A (en) | 1995-07-18 |
ZA956993B (en) | 1997-02-21 |
US5530010A (en) | 1996-06-25 |
EP0769943A4 (en) | 1999-07-07 |
CA2198114A1 (en) | 1996-02-29 |
AU3368595A (en) | 1996-03-14 |
WO1996005823A1 (en) | 1996-02-29 |
JPH10505823A (ja) | 1998-06-09 |
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