MX9705697A - Metodos para reducir los niveles de calcio del suero. - Google Patents
Metodos para reducir los niveles de calcio del suero.Info
- Publication number
- MX9705697A MX9705697A MX9705697A MX9705697A MX9705697A MX 9705697 A MX9705697 A MX 9705697A MX 9705697 A MX9705697 A MX 9705697A MX 9705697 A MX9705697 A MX 9705697A MX 9705697 A MX9705697 A MX 9705697A
- Authority
- MX
- Mexico
- Prior art keywords
- calcium levels
- serum calcium
- methods
- decreasing serum
- decreasing
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- 210000002966 serum Anatomy 0.000 title abstract 2
- 230000003247 decreasing effect Effects 0.000 title 1
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 hexamethyleneimino Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Liquid Crystal Substances (AREA)
Abstract
La presente invencion se refiere a un método para reducir los niveles de calcio del suero, que comprende la administracion a un ser humano que tenga la necesidad del mismo, de un compuesto que tiene la formula (I), en donde R1 y R3 son independientemente hidrogeno, -CH3, (a), o (b), en donde Ar es fenilo substituido opcionalmente; R2 se selecciona del grupo que consiste de pirrolidina, hexametilenimino, y piperidino; o una sal o solvato del mismo aceptable farmacéuticamente.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/380,881 US5512583A (en) | 1995-01-30 | 1995-01-30 | Methods of decreasing serum calcium levels |
| US08380881 | 1995-01-30 | ||
| PCT/US1996/001406 WO1996023501A1 (en) | 1995-01-30 | 1996-01-29 | Methods of decreasing serum calcium levels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9705697A true MX9705697A (es) | 1997-10-31 |
| MXPA97005697A MXPA97005697A (es) | 1998-07-03 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996023501A1 (en) | 1996-08-08 |
| ES2172633T3 (es) | 2002-10-01 |
| DK0723780T3 (da) | 2002-06-17 |
| UA43389C2 (uk) | 2001-12-17 |
| CN1086943C (zh) | 2002-07-03 |
| NO973470L (no) | 1997-07-28 |
| JPH10513184A (ja) | 1998-12-15 |
| DE69620661T2 (de) | 2002-11-14 |
| CZ286161B6 (cs) | 2000-01-12 |
| RU2176503C2 (ru) | 2001-12-10 |
| CA2211530A1 (en) | 1996-08-08 |
| EP0723780A3 (es) | 1996-09-11 |
| NZ302546A (en) | 2000-06-23 |
| EP0723780B1 (en) | 2002-04-17 |
| HUP9801335A3 (en) | 2000-03-28 |
| ATE216232T1 (de) | 2002-05-15 |
| AU4862296A (en) | 1996-08-21 |
| PT723780E (pt) | 2002-08-30 |
| DE69620661D1 (de) | 2002-05-23 |
| US5512583A (en) | 1996-04-30 |
| HUP9801335A2 (hu) | 1999-05-28 |
| KR19980701731A (ko) | 1998-06-25 |
| CZ240397A3 (cs) | 1998-01-14 |
| CN1172432A (zh) | 1998-02-04 |
| AU701262B2 (en) | 1999-01-21 |
| NO973470D0 (no) | 1997-07-28 |
| EP0723780A2 (en) | 1996-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9701325A (es) | Metodos para inhibir la mucositis ulcerativa. | |
| AU8155894A (en) | Methods of inhibiting thrombin | |
| MX9701329A (es) | Metodos para la inhibicion de la replicacion viral. | |
| AU7578794A (en) | Methods for inhibiting endometriosis | |
| MY132251A (en) | Methods of inhibiting cell-cell adhesion | |
| MX9701360A (es) | Metodos para la inhibicion de la desmielinizacion y las enfermedades de la dismielinizacion. | |
| MY112973A (en) | Methods for inhibiting vascular smooth muscle cell migration | |
| AU7583494A (en) | Methods of inhibiting uterine fibrosis | |
| AU8156194A (en) | Methods of inhibiting dysfunctional uterine bleeding | |
| UA27910C2 (uk) | Засіб для підвищення експресії тромбомодуліну та підвищення активації протеїну с | |
| MX9709466A (es) | Medicamento para inhibir el melanoma. | |
| EA199700136A1 (ru) | Способы ингибирования экзогенных эстрогенов | |
| MX9701333A (es) | Metodos para inhibir el daño neuronal. | |
| MY113406A (en) | Methods of inhibiting physiological conditions associated with an excess of bradykinin | |
| IL115016A0 (en) | Methods for bone healing and fracture repair | |
| MX9705697A (es) | Metodos para reducir los niveles de calcio del suero. | |
| AU3409895A (en) | Methods of inhibiting primary endometrial hyperplasia | |
| MX9701328A (es) | Metodos de reduccion de la cicatrizacion en la curacion de heridas. | |
| MX9709651A (es) | Metodos para modulacion del factor de transcripcion nf-kb. | |
| MX9709536A (es) | Metodo para reducir el factor de transcripcion bef-1. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |