GB1336732A - Diethanolamine derivatives - Google Patents

Diethanolamine derivatives

Info

Publication number
GB1336732A
GB1336732A GB5122870A GB5122870A GB1336732A GB 1336732 A GB1336732 A GB 1336732A GB 5122870 A GB5122870 A GB 5122870A GB 5122870 A GB5122870 A GB 5122870A GB 1336732 A GB1336732 A GB 1336732A
Authority
GB
United Kingdom
Prior art keywords
compounds
diethanolamines
morpholines
salts
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5122870A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Gentili SpA
Original Assignee
Istituto Gentili SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Gentili SpA filed Critical Istituto Gentili SpA
Priority to GB5122870A priority Critical patent/GB1336732A/en
Priority to AU34072/71A priority patent/AU3407271A/en
Priority to AR23859171A priority patent/AR192325A1/en
Priority to DE19712152686 priority patent/DE2152686A1/en
Priority to NL7114581A priority patent/NL7114581A/xx
Priority to FR7138592A priority patent/FR2111882A1/fr
Priority to CA126216A priority patent/CA934373A/en
Priority to BE774629A priority patent/BE774629A/en
Publication of GB1336732A publication Critical patent/GB1336732A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1336732 Diethanolamines; morpholines ISTITUTO GENTILI SpA-PISA 28 Oct 1970 51228/70 Heading C2C Compounds of the general formula (Ar=Ph optionally substituted by one or more alkoxy groups; R 1-3 =H, alkyl; provided that at least one of R 1-3 =H, R 2 and R 3 =H when R 1 = alkyl, and when R 2 and R 3 = H the ring is substituted) and salts thereof are prepared by reacting the appropriate styrene oxide and aminoethanol, or arylethanolamine and ethylene chlorohydrin or ethylene oxide. These compounds may be ring-closed to the corresponding morpholines and salts thereof. Some of the above compounds are convulsants, and some of the diethanolamines are diuretics. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB5122870A 1970-10-28 1970-10-28 Diethanolamine derivatives Expired GB1336732A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GB5122870A GB1336732A (en) 1970-10-28 1970-10-28 Diethanolamine derivatives
AU34072/71A AU3407271A (en) 1970-10-28 1971-09-30 New diethanolamine and morpholine derivatives
AR23859171A AR192325A1 (en) 1970-10-28 1971-10-21 A PROCEDURE FOR THE PREPARATION OF COMPOUNDS DERIVED FROM SUBSTITUTED MORPHOLINS
DE19712152686 DE2152686A1 (en) 1970-10-28 1971-10-22 New derivatives of diaethanolamine and morpholine and processes for their preparation
NL7114581A NL7114581A (en) 1970-10-28 1971-10-22
FR7138592A FR2111882A1 (en) 1970-10-28 1971-10-27
CA126216A CA934373A (en) 1970-10-28 1971-10-27 Diethanolamine and morpholine derivatives
BE774629A BE774629A (en) 1970-10-28 1971-10-28 DIETHANOLAMINE AND MORPHOLINE DERIVATIVES AND THEIR PREPARATION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5122870A GB1336732A (en) 1970-10-28 1970-10-28 Diethanolamine derivatives

Publications (1)

Publication Number Publication Date
GB1336732A true GB1336732A (en) 1973-11-07

Family

ID=10459148

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5122870A Expired GB1336732A (en) 1970-10-28 1970-10-28 Diethanolamine derivatives

Country Status (8)

Country Link
AR (1) AR192325A1 (en)
AU (1) AU3407271A (en)
BE (1) BE774629A (en)
CA (1) CA934373A (en)
DE (1) DE2152686A1 (en)
FR (1) FR2111882A1 (en)
GB (1) GB1336732A (en)
NL (1) NL7114581A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027695A1 (en) * 1979-10-20 1981-04-29 JOHN WYETH & BROTHER LIMITED Morpholine derivatives, pharmaceutical compositions containing them and processes for their preparation
WO1992018489A1 (en) * 1991-04-23 1992-10-29 The Wellcome Foundation Limited Arylmorpholine, preparation and use
WO2006079809A1 (en) * 2005-01-25 2006-08-03 Norgine Europe Bv Compounds for treating urinary incontinence
US8906908B2 (en) 2010-05-21 2014-12-09 Research Triangle Institute Hydroxybupropion analogues for treating drug dependence
US9562001B2 (en) 2009-04-15 2017-02-07 Research Triangle Institute Monoamine reuptake inhibitors
US9617229B2 (en) 2010-05-21 2017-04-11 Research Triangle Institute Phenylmorpholines and analogues thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471378A1 (en) * 1979-12-14 1981-06-19 Lafon Labor Alkylated 2:phenyl morpholine derivs. - having antidepressant and cardiovascular activity, prepd. by cyclising hydroxyalkyl phenyl ethanol(s)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027695A1 (en) * 1979-10-20 1981-04-29 JOHN WYETH & BROTHER LIMITED Morpholine derivatives, pharmaceutical compositions containing them and processes for their preparation
WO1992018489A1 (en) * 1991-04-23 1992-10-29 The Wellcome Foundation Limited Arylmorpholine, preparation and use
US5648347A (en) * 1991-04-23 1997-07-15 Glaxo Wellcome Inc. Arylmorpholine, preparation and use
WO2006079809A1 (en) * 2005-01-25 2006-08-03 Norgine Europe Bv Compounds for treating urinary incontinence
JP2008528474A (en) * 2005-01-25 2008-07-31 ノージン ヨーロッパ ビーブイ Compounds for the treatment of urinary incontinence
US9562001B2 (en) 2009-04-15 2017-02-07 Research Triangle Institute Monoamine reuptake inhibitors
US10919841B2 (en) 2009-04-15 2021-02-16 Research Triangle Institute Monoamine reuptake inhibitors
US8906908B2 (en) 2010-05-21 2014-12-09 Research Triangle Institute Hydroxybupropion analogues for treating drug dependence
US9527823B2 (en) 2010-05-21 2016-12-27 Research Triangle Institute Hydroxybupropion analogues for treating drug dependence
US9617229B2 (en) 2010-05-21 2017-04-11 Research Triangle Institute Phenylmorpholines and analogues thereof

Also Published As

Publication number Publication date
BE774629A (en) 1972-02-14
NL7114581A (en) 1972-05-03
AR192325A1 (en) 1973-02-14
CA934373A (en) 1973-09-25
DE2152686A1 (en) 1972-05-10
FR2111882A1 (en) 1972-06-09
AU3407271A (en) 1973-04-05

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Legal Events

Date Code Title Description
416 Proceeding under section 16 patents act 1949
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees