AU2018258049B2 - Constructs specifically recognizing glypican 3 and uses thereof - Google Patents

Constructs specifically recognizing glypican 3 and uses thereof Download PDF

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Publication number
AU2018258049B2
AU2018258049B2 AU2018258049A AU2018258049A AU2018258049B2 AU 2018258049 B2 AU2018258049 B2 AU 2018258049B2 AU 2018258049 A AU2018258049 A AU 2018258049A AU 2018258049 A AU2018258049 A AU 2018258049A AU 2018258049 B2 AU2018258049 B2 AU 2018258049B2
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amino acid
seq
acid sequence
gpc3
cdr2
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AU2018258049A1 (en
Inventor
Timothy ACKER
Hong Liu
Javier Morales
Yoko Nakano
Jingyi Xiang
Yiyang XU
Pengbo Zhang
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Eureka Therapeutics Inc
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Eureka Therapeutics Inc
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    • A61K39/0011—Cancer antigens
    • A61K39/00118—Cancer antigens from embryonic or fetal origin
    • A61K39/001181—Alpha-feto protein
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    • A61K40/4261—Proteoglycans, e.g. glypican, brevican or CSPG4
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    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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AU2018258049A 2017-04-26 2018-04-24 Constructs specifically recognizing glypican 3 and uses thereof Active AU2018258049B2 (en)

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Application Number Priority Date Filing Date Title
US201762490586P 2017-04-26 2017-04-26
US62/490,586 2017-04-26
PCT/US2018/029221 WO2018200586A1 (en) 2017-04-26 2018-04-24 Constructs specifically recognizing glypican 3 and uses thereof

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AU2018258049B2 true AU2018258049B2 (en) 2025-03-27

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EP (1) EP3615574A4 (enExample)
JP (2) JP7295030B2 (enExample)
KR (2) KR20240067275A (enExample)
CN (1) CN110741019B (enExample)
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WO2018200585A1 (en) 2017-04-26 2018-11-01 Eureka Therapeutics, Inc. Cells expressing chimeric antigen receptors and secondary effectors and uses thereof
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