AU2018224094B2 - Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof - Google Patents

Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof Download PDF

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AU2018224094B2
AU2018224094B2 AU2018224094A AU2018224094A AU2018224094B2 AU 2018224094 B2 AU2018224094 B2 AU 2018224094B2 AU 2018224094 A AU2018224094 A AU 2018224094A AU 2018224094 A AU2018224094 A AU 2018224094A AU 2018224094 B2 AU2018224094 B2 AU 2018224094B2
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dart
seq
cooh
mab
trident
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AU2018224094A1 (en
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Ezio Bonvini
Gundo Diedrich
Leslie S. Johnson
Chia-Ying Kao Lam
Liqin Liu
Paul A. Moore
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Macrogenics Inc
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Macrogenics Inc
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    • G11C15/04—Digital stores in which information comprising one or more characteristic parts is written into the store and in which information is read-out by searching for one or more of these characteristic parts, i.e. associative or content-addressed stores using semiconductor elements
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K—PEPTIDES
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    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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AU2018224094A 2017-02-24 2018-02-22 Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof Active AU2018224094B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762463353P 2017-02-24 2017-02-24
US62/463,353 2017-02-24
US201762597594P 2017-12-12 2017-12-12
US62/597,594 2017-12-12
PCT/US2018/019188 WO2018156740A1 (en) 2017-02-24 2018-02-22 Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof

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AU2018224094A1 AU2018224094A1 (en) 2019-09-19
AU2018224094B2 true AU2018224094B2 (en) 2025-04-17

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EP (2) EP3585431A4 (cg-RX-API-DMAC7.html)
JP (1) JP7132232B2 (cg-RX-API-DMAC7.html)
KR (1) KR102585848B1 (cg-RX-API-DMAC7.html)
CN (1) CN110325209A (cg-RX-API-DMAC7.html)
AU (1) AU2018224094B2 (cg-RX-API-DMAC7.html)
BR (1) BR112019017628A2 (cg-RX-API-DMAC7.html)
CA (1) CA3053803A1 (cg-RX-API-DMAC7.html)
IL (1) IL268836B2 (cg-RX-API-DMAC7.html)
MA (1) MA47612A (cg-RX-API-DMAC7.html)
MX (1) MX2019009967A (cg-RX-API-DMAC7.html)
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