JP7132232B2 - Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 - Google Patents

Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 Download PDF

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JP7132232B2
JP7132232B2 JP2019546216A JP2019546216A JP7132232B2 JP 7132232 B2 JP7132232 B2 JP 7132232B2 JP 2019546216 A JP2019546216 A JP 2019546216A JP 2019546216 A JP2019546216 A JP 2019546216A JP 7132232 B2 JP7132232 B2 JP 7132232B2
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seq
cdr
mab
binding
binding molecule
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リキン リュウ
チャーイン カオ ラム
グンド ディードリッヒ
レスリー エス． ジョンソン
ポール エー． ムーア
エツィオ ボンビニ
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マクロジェニクス，インコーポレーテッド
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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JP2019546216A 2017-02-24 2018-02-22 Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 Active JP7132232B2 (ja)

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US201762463353P 2017-02-24 2017-02-24
US62/463,353 2017-02-24
US201762597594P 2017-12-12 2017-12-12
US62/597,594 2017-12-12
PCT/US2018/019188 WO2018156740A1 (en) 2017-02-24 2018-02-22 Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof

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