AU2016228080B2 - Reducing immune tolerance induced by PD-L1 - Google Patents

Reducing immune tolerance induced by PD-L1 Download PDF

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Publication number
AU2016228080B2
AU2016228080B2 AU2016228080A AU2016228080A AU2016228080B2 AU 2016228080 B2 AU2016228080 B2 AU 2016228080B2 AU 2016228080 A AU2016228080 A AU 2016228080A AU 2016228080 A AU2016228080 A AU 2016228080A AU 2016228080 B2 AU2016228080 B2 AU 2016228080B2
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modified
cell
cells
acid sequence
nucleic acid
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AU2016228080A1 (en
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Zhao Wu
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Innovative Cellular Therapeutics Holdings Ltd Grand Cayman
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Innovative Cellular Therapeutics Holdings Ltd Grand Cayman
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Assigned to Innovative Cellular Therapeutics CO., LTD. reassignment Innovative Cellular Therapeutics CO., LTD. Alteration of Name(s) of Applicant(s) under S113 Assignors: SHANGHAI SIDANSAI BIOTECHNOLOGY CO., LTD
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Assigned to INNOVATIVE CELLULAR THERAPEUTICS HOLDINGS, LTD. reassignment INNOVATIVE CELLULAR THERAPEUTICS HOLDINGS, LTD. Request for Assignment Assignors: Innovative Cellular Therapeutics CO., LTD.
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K2319/00—Fusion polypeptide
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

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AU2016228080A 2015-03-02 2016-03-01 Reducing immune tolerance induced by PD-L1 Ceased AU2016228080B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562126804P 2015-03-02 2015-03-02
US62/126,804 2015-03-02
PCT/CN2016/075061 WO2016138846A1 (en) 2015-03-02 2016-03-01 Reducing immune tolerance induced by pd‐l1

Publications (2)

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AU2016228080A1 AU2016228080A1 (en) 2017-09-07
AU2016228080B2 true AU2016228080B2 (en) 2020-11-12

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AU2016228080A Ceased AU2016228080B2 (en) 2015-03-02 2016-03-01 Reducing immune tolerance induced by PD-L1

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US (4) US9572837B2 (enExample)
EP (2) EP3549612B1 (enExample)
JP (2) JP6336684B2 (enExample)
KR (1) KR102133857B1 (enExample)
CN (2) CN108410892B (enExample)
AU (1) AU2016228080B2 (enExample)
BR (1) BR112017018770A2 (enExample)
CA (1) CA2976684C (enExample)
RU (1) RU2688692C2 (enExample)
SG (1) SG11201706947TA (enExample)
WO (1) WO2016138846A1 (enExample)

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