AU2015350103A1 - Engineered gamma delta T-cells - Google Patents
Engineered gamma delta T-cells Download PDFInfo
- Publication number
- AU2015350103A1 AU2015350103A1 AU2015350103A AU2015350103A AU2015350103A1 AU 2015350103 A1 AU2015350103 A1 AU 2015350103A1 AU 2015350103 A AU2015350103 A AU 2015350103A AU 2015350103 A AU2015350103 A AU 2015350103A AU 2015350103 A1 AU2015350103 A1 AU 2015350103A1
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- AU
- Australia
- Prior art keywords
- cell
- engineered
- antigen
- cells
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
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- A61K40/31—Chimeric antigen receptors [CAR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C—CHEMISTRY; METALLURGY
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
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- Hematology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2021221785A AU2021221785B2 (en) | 2014-11-17 | 2021-08-25 | Engineered gamma delta T-cells |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462080500P | 2014-11-17 | 2014-11-17 | |
| US62/080,500 | 2014-11-17 | ||
| PCT/US2015/061189 WO2016081518A2 (en) | 2014-11-17 | 2015-11-17 | Engineered gamma delta t-cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021221785A Division AU2021221785B2 (en) | 2014-11-17 | 2021-08-25 | Engineered gamma delta T-cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2015350103A1 true AU2015350103A1 (en) | 2017-06-29 |
Family
ID=56014675
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015350103A Abandoned AU2015350103A1 (en) | 2014-11-17 | 2015-11-17 | Engineered gamma delta T-cells |
| AU2021221785A Active AU2021221785B2 (en) | 2014-11-17 | 2021-08-25 | Engineered gamma delta T-cells |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021221785A Active AU2021221785B2 (en) | 2014-11-17 | 2021-08-25 | Engineered gamma delta T-cells |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11135245B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP4545639A3 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7146397B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102660362B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN117143814A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2015350103A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2966634C (cg-RX-API-DMAC7.html) |
| DK (1) | DK3220926T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES3023783T3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL252131B2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2017006408A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2756247C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016081518A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201703505B (cg-RX-API-DMAC7.html) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT1814580T (lt) | 2004-11-24 | 2016-12-12 | Fred Hutchinson Cancer Research Center | Il 21 naudojimo pritaikomajai imunoterapijai ir naviko antigenų identifikavimo metodai |
| GB201506423D0 (en) | 2015-04-15 | 2015-05-27 | Tc Biopharm Ltd | Gamma delta T cells and uses thereof |
| AU2015350103A1 (en) | 2014-11-17 | 2017-06-29 | Adicet Bio, Inc. | Engineered gamma delta T-cells |
| WO2016122320A1 (en) | 2015-01-27 | 2016-08-04 | Stichting Vu-Vumc | Single domain antibodies targeting cd1d |
| GB201507368D0 (en) | 2015-04-30 | 2015-06-17 | Ucl Business Plc | Cell |
| ES2908840T3 (es) | 2015-06-09 | 2022-05-04 | Lymphact Lymphocyte Activation Tech S A | Procedimiento para la producción de células T TCR gamma delta+ |
| EP3344760B1 (en) | 2015-09-03 | 2022-01-12 | The UAB Research Foundation | Genetically-engineered drug resistant t cells and methods of using the same |
| EP3454870A4 (en) * | 2016-05-12 | 2020-03-04 | Adicet Bio Inc. | METHOD FOR SELECTIVE EXPANSION OF GAMMA DELTA T CELL POPULATIONS AND COMPOSITIONS THEREOF |
| US10426796B2 (en) * | 2016-06-13 | 2019-10-01 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US10456423B2 (en) | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| CA3032429A1 (en) | 2016-08-03 | 2018-02-08 | Washington University | Gene editing of car-t cells for the treatment of t cell malignancies with chimeric antigen receptors |
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