EP1229790A4 - MODULATION OF $g(g)$g(d) T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS - Google Patents

MODULATION OF $g(g)$g(d) T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS

Info

Publication number
EP1229790A4
EP1229790A4 EP00967029A EP00967029A EP1229790A4 EP 1229790 A4 EP1229790 A4 EP 1229790A4 EP 00967029 A EP00967029 A EP 00967029A EP 00967029 A EP00967029 A EP 00967029A EP 1229790 A4 EP1229790 A4 EP 1229790A4
Authority
EP
European Patent Office
Prior art keywords
modulation
cells
airway hyperresponsiveness
regulate airway
regulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP00967029A
Other languages
German (de)
French (fr)
Other versions
EP1229790A1 (en
Inventor
Erwin Gelfand
Willi K Born
Michael F Lahn
Arihiko Kanehiro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Jewish Health
Original Assignee
National Jewish Medical and Research Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Jewish Medical and Research Center filed Critical National Jewish Medical and Research Center
Publication of EP1229790A1 publication Critical patent/EP1229790A1/en
Publication of EP1229790A4 publication Critical patent/EP1229790A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP00967029A 1999-09-30 2000-09-28 MODULATION OF $g(g)$g(d) T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS Ceased EP1229790A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15723199P 1999-09-30 1999-09-30
US157231P 1999-09-30
PCT/US2000/026684 WO2001022816A1 (en) 1999-09-30 2000-09-28 MODULATION OF ηδ T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS

Publications (2)

Publication Number Publication Date
EP1229790A1 EP1229790A1 (en) 2002-08-14
EP1229790A4 true EP1229790A4 (en) 2004-06-16

Family

ID=22562868

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00967029A Ceased EP1229790A4 (en) 1999-09-30 2000-09-28 MODULATION OF $g(g)$g(d) T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS

Country Status (3)

Country Link
EP (1) EP1229790A4 (en)
AU (1) AU7729000A (en)
WO (1) WO2001022816A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8178098B2 (en) 2001-04-03 2012-05-15 National Jewish Health Method to inhibit airway hyperresponsiveness using aerosolized T cell receptor antibodies
JP4607451B2 (en) 2001-07-20 2011-01-05 バイオエージェンシー・アーゲー Organophosphorus compounds for activating gamma / delta T cells
US20230009275A1 (en) * 2019-12-03 2023-01-12 Adicet Bio, Inc. Methods for expanding gamma delta t-cell populations with multivalent agents and compositions thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200002973T2 (en) * 1998-01-23 2001-02-21 National Jewish Medical And Research Center Treating inflammatory diseases using heat shock proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MUNK MARTIN E ET AL: "Human CD30+ cells are induced by Mycobacterium tuberculosis and present in tuberculosis lesions", INTERNATIONAL IMMUNOLOGY, OXFORD UNIVERSITY PRESS, GB, vol. 9, no. 5, 1997, pages 713 - 720, XP002202326, ISSN: 0953-8178 *
See also references of WO0122816A1 *

Also Published As

Publication number Publication date
AU7729000A (en) 2001-04-30
WO2001022816A1 (en) 2001-04-05
EP1229790A1 (en) 2002-08-14

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20020430

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: GELFAND, ERWIN

Inventor name: BORN, WILLI, K.

Inventor name: LAHN, MICHAEL, F.

Inventor name: KANEHIRO, ARIHIKO

A4 Supplementary search report drawn up and despatched

Effective date: 20040507

RIC1 Information provided on ipc code assigned before grant

Ipc: 7G 01N 33/53 B

Ipc: 7C 07K 14/00 B

Ipc: 7A 01N 37/18 A

Ipc: 7C 12Q 1/00 B

Ipc: 7C 07K 14/35 B

Ipc: 7C 07K 1/00 B

Ipc: 7G 01N 33/50 B

Ipc: 7C 07K 7/06 B

Ipc: 7A 61K 38/19 B

17Q First examination report despatched

Effective date: 20041123

RTI1 Title (correction)

Free format text: MODULATION OFGAMMA-DELTA T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS

STAA Information on the status of an ep patent application or granted ep patent

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Effective date: 20090312