AU2015301632B2 - Signal amplification in plasmonic specific-binding partner assays - Google Patents

Signal amplification in plasmonic specific-binding partner assays Download PDF

Info

Publication number
AU2015301632B2
AU2015301632B2 AU2015301632A AU2015301632A AU2015301632B2 AU 2015301632 B2 AU2015301632 B2 AU 2015301632B2 AU 2015301632 A AU2015301632 A AU 2015301632A AU 2015301632 A AU2015301632 A AU 2015301632A AU 2015301632 B2 AU2015301632 B2 AU 2015301632B2
Authority
AU
Australia
Prior art keywords
metallic
nanostructures
lspr
gold
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2015301632A
Other languages
English (en)
Other versions
AU2015301632A1 (en
Inventor
Kenneth P. Aron
Vincent Chiang
Asher KRELL
Rajesh K. Mehra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoetis Services LLC
Original Assignee
Zoetis Services LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services LLC filed Critical Zoetis Services LLC
Publication of AU2015301632A1 publication Critical patent/AU2015301632A1/en
Assigned to ZOETIS SERVICES LLC reassignment ZOETIS SERVICES LLC Request for Assignment Assignors: ABAXIS, INC.
Priority to AU2021202253A priority Critical patent/AU2021202253B2/en
Application granted granted Critical
Publication of AU2015301632B2 publication Critical patent/AU2015301632B2/en
Priority to AU2023270256A priority patent/AU2023270256B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2015301632A 2014-08-13 2015-08-13 Signal amplification in plasmonic specific-binding partner assays Active AU2015301632B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2021202253A AU2021202253B2 (en) 2014-08-13 2021-04-14 Signal amplification in plasmonic specific-binding partner assays
AU2023270256A AU2023270256B2 (en) 2014-08-13 2023-11-22 Signal amplification in plasmonic specific-binding partner assays

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462037071P 2014-08-13 2014-08-13
US62/037,071 2014-08-13
US201462082468P 2014-11-20 2014-11-20
US62/082,468 2014-11-20
PCT/US2015/045041 WO2016025703A2 (en) 2014-08-13 2015-08-13 Signal amplification in plasmonic specific-binding partner assays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2021202253A Division AU2021202253B2 (en) 2014-08-13 2021-04-14 Signal amplification in plasmonic specific-binding partner assays

Publications (2)

Publication Number Publication Date
AU2015301632A1 AU2015301632A1 (en) 2017-03-02
AU2015301632B2 true AU2015301632B2 (en) 2021-05-06

Family

ID=55302002

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2015301632A Active AU2015301632B2 (en) 2014-08-13 2015-08-13 Signal amplification in plasmonic specific-binding partner assays
AU2021202253A Active AU2021202253B2 (en) 2014-08-13 2021-04-14 Signal amplification in plasmonic specific-binding partner assays
AU2023270256A Active AU2023270256B2 (en) 2014-08-13 2023-11-22 Signal amplification in plasmonic specific-binding partner assays

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2021202253A Active AU2021202253B2 (en) 2014-08-13 2021-04-14 Signal amplification in plasmonic specific-binding partner assays
AU2023270256A Active AU2023270256B2 (en) 2014-08-13 2023-11-22 Signal amplification in plasmonic specific-binding partner assays

Country Status (18)

Country Link
US (3) US10488409B2 (enExample)
EP (2) EP3943943A1 (enExample)
JP (3) JP6945445B2 (enExample)
KR (2) KR102787948B1 (enExample)
CN (2) CN106796228B (enExample)
AU (3) AU2015301632B2 (enExample)
CA (2) CA3209879A1 (enExample)
DK (1) DK3180619T3 (enExample)
ES (1) ES2888230T3 (enExample)
HU (1) HUE056514T2 (enExample)
IL (4) IL300266B2 (enExample)
MX (2) MX2017001905A (enExample)
PL (1) PL3180619T3 (enExample)
PT (1) PT3180619T (enExample)
SG (2) SG11201700864WA (enExample)
TW (1) TWI691716B (enExample)
WO (1) WO2016025703A2 (enExample)
ZA (1) ZA201700873B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
WO2016187588A1 (en) * 2015-05-21 2016-11-24 Lamdagen Corporation Plasmonic nanoparticles and lspr-based assays
DK3331818T3 (da) 2015-08-04 2024-08-12 Zoetis Services Llc Signalforstærkning i opløsningsbaserede plasmoniske assays med specifkke bindingspartnere
JP2017150865A (ja) * 2016-02-23 2017-08-31 コニカミノルタ株式会社 ガス検知方法及びガス検知装置
KR101842763B1 (ko) * 2016-03-11 2018-05-14 경희대학교 산학협력단 구리 나노구조물의 제조방법
CA3051465A1 (en) 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures
JP6926731B2 (ja) * 2017-06-30 2021-08-25 コニカミノルタ株式会社 検出チップ、検出キット、検出システムおよび被検出物質の検出方法
EP3775896B1 (en) * 2018-04-03 2023-06-07 Sanofi Lateral flow immunoassay strip device
CN111024942B (zh) * 2019-11-27 2023-06-02 北京农业智能装备技术研究中心 一种免疫层析试纸条的高灵敏检测方法
WO2022221946A1 (en) * 2021-04-21 2022-10-27 Nicoya Lifesciences, Inc. System and method for simulating a localized surface plasmon resonance (lspr) spectrometer
WO2024196805A1 (en) 2023-03-17 2024-09-26 Beckman Coulter, Inc. Benzothienopyrrole cyanine dyes
WO2025014842A1 (en) * 2023-07-07 2025-01-16 Ohio University Test strips and methods of testing for bio-analytes using titanium nitride nanoparticles and gold coated copper nanoparticles
EP4567426A1 (en) * 2023-12-05 2025-06-11 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) A nanoparticle, a suspension comprising nanoparticles, and related method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100062545A1 (en) * 2005-06-15 2010-03-11 University Of Maryland Biotechnology Institute Bioassays using plasmonic scattering from noble metal nanostructures
US20130034854A1 (en) * 2010-04-27 2013-02-07 Ventana Medical Systems, Inc. Antibody-Nanoparticle Conjugates and Methods for Making and Using Such Conjugates

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
JPH03164195A (ja) * 1989-11-22 1991-07-16 Idemitsu Petrochem Co Ltd 液体試料の分析方法及び分析装置
US5122284A (en) 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
US5186844A (en) 1991-04-01 1993-02-16 Abaxis, Inc. Apparatus and method for continuous centrifugal blood cell separation
US5061381A (en) 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5413732A (en) 1991-08-19 1995-05-09 Abaxis, Inc. Reagent compositions for analytical testing
US5304348A (en) 1992-02-11 1994-04-19 Abaxis, Inc. Reagent container for analytical rotor
AU4047493A (en) 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
JP3706214B2 (ja) 1996-10-28 2005-10-12 株式会社三菱化学ヤトロン 免疫学的分析方法
US5939021A (en) 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
WO1998037417A1 (en) 1997-02-20 1998-08-27 The Regents Of The University Of California Plasmon resonant particles, methods and apparatus
US7144627B2 (en) 1997-03-12 2006-12-05 William Marsh Rice University Multi-layer nanoshells comprising a metallic or conducting shell
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US6699724B1 (en) 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
JP3841559B2 (ja) 1998-07-07 2006-11-01 日東電工株式会社 免疫学的検査方法および免疫学的検査キット
JP2000028612A (ja) 1998-07-07 2000-01-28 Nitto Denko Corp 免疫学的検査方法および免疫学的検査キット
JP3298836B2 (ja) 1998-11-12 2002-07-08 アークレイ株式会社 検体分析用具
WO2001009388A1 (en) 1999-07-30 2001-02-08 The Penn State Research Foundation Instruments, methods and reagents for surface plasmon resonance
WO2001035081A1 (en) 1999-11-12 2001-05-17 Surromed, Inc. Biosensing using surface plasmon resonance
WO2002079764A1 (en) 2001-01-26 2002-10-10 Nanoplex Technologies, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
US6660381B2 (en) 2000-11-03 2003-12-09 William Marsh Rice University Partial coverage metal nanoshells and method of making same
US7238472B2 (en) * 2001-05-25 2007-07-03 Nanosphere, Inc. Non-alloying core shell nanoparticles
US7135054B2 (en) 2001-09-26 2006-11-14 Northwestern University Nanoprisms and method of making them
CN1417586A (zh) 2001-11-05 2003-05-14 福州市迈新生物技术开发公司 一种免疫检测信号放大系统和它的制备方法及其应用
US6970239B2 (en) 2002-06-12 2005-11-29 Intel Corporation Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate
US7212692B2 (en) 2002-11-08 2007-05-01 Ming Yan Multiple array surface plasmon resonance biosensor
JP4787938B2 (ja) 2003-03-28 2011-10-05 ザ・プロウボウスト・フェロウズ・ファウンデーション・スカラーズ・アンド・ザ・アザー・メンバーズ・オブ・ボード・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン 銀ナノ粒子を用いた検体検出用センサ
KR100531760B1 (ko) 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US20060240573A1 (en) 2003-07-29 2006-10-26 Lamdagen, Llc Optical system including nanostructures for biological or chemical sensing
GB0321937D0 (en) * 2003-09-19 2003-10-22 Univ Liverpool Nanoparticle conjugates and method of production thereof
US20070298432A1 (en) * 2003-11-07 2007-12-27 Hep-Genics Pty Ltd Binding Assay Components
JP4109205B2 (ja) 2004-01-07 2008-07-02 富士フイルム株式会社 被検体検出方法
WO2007040559A2 (en) 2004-11-17 2007-04-12 Bioveris Electrochemiluminescent assay
CN1296492C (zh) 2004-11-18 2007-01-24 博奥生物有限公司 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
US7405054B1 (en) 2004-12-13 2008-07-29 University Of Washington Uw Tech Transfer - Invention Licensing Signal amplification method for surface plasmon resonance-based chemical detection
US8628727B2 (en) 2005-04-08 2014-01-14 Northwestern University Compositions, devices and methods for SERS and LSPR
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
US20070092978A1 (en) 2005-10-20 2007-04-26 Ronald Mink Target ligand detection
JP5442179B2 (ja) 2005-10-21 2014-03-12 アルフレッサファーマ株式会社 反応性物質が結合した微小粒子の沈降抑制方法および該微小粒子含有試薬
EP2308900B1 (en) 2005-10-25 2014-02-12 Artificial Cell Technologies, Inc. Immunogenic compositions and methods of use
JP4837743B2 (ja) 2005-11-18 2011-12-14 アメリカ合衆国 修飾カルジオリピンおよびその使用法
WO2007103802A2 (en) 2006-03-03 2007-09-13 William Marsh Rice University Nanorice particles: hybrid plasmonic nanostructures
JP4810304B2 (ja) 2006-05-12 2011-11-09 キヤノン株式会社 化学センサ素子及びその製造方法
EP2126570A1 (en) * 2006-06-06 2009-12-02 Vivacta Limited A method for sensing a chemical
US8426152B2 (en) 2007-01-03 2013-04-23 Lamdagen Corporation Enzymatic assay for LSPR
MX2009009994A (es) 2007-03-20 2009-10-19 Becton Dickinson Co Ensayos que usan particulas activas para espectroscopia raman mejorada por superficie (sers).
JP2009150708A (ja) * 2007-12-19 2009-07-09 Canon Inc 標的物質の検出方法及び検査キット
EP2229251B1 (en) 2007-12-21 2013-03-20 The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin A process for preparing nanoparticles
WO2009117510A2 (en) 2008-03-20 2009-09-24 Abaxis, Inc. Multi-wavelength analyses of sol-particle specific binding assays
WO2010006201A2 (en) 2008-07-10 2010-01-14 Abaxis, Inc. Methods of reducing non-specific interaction in metal nanoparticle assays
WO2010065781A2 (en) 2008-12-03 2010-06-10 Abaxis, Inc. Lateral flow strip assay with immobilized conjugate
US8313915B2 (en) 2009-01-21 2012-11-20 Gundersen Lutheran Medical Foundation, Inc. Early detection of canine lyme disease by specific peptides and antibodies
WO2010091293A1 (en) 2009-02-06 2010-08-12 The Regents Of The University Of California Plasmonic system for detecting binding of biological molecules
BRPI1008760B1 (pt) 2009-02-27 2019-12-10 Beckman Coulter Inc método de ensaio e kit para um analito em uma amostra e sistema para realizar o método de ensaio
WO2010116346A1 (en) 2009-04-08 2010-10-14 National University Of Ireland, Galway Silver nanoplates
JP5563789B2 (ja) * 2009-06-11 2014-07-30 富士フイルム株式会社 検出方法
JP2013511530A (ja) 2009-11-17 2013-04-04 アバクシス， インコーポレイテッド ライム病抗体の検出のためのペプチドおよび方法
JP6161291B2 (ja) 2009-11-20 2017-07-12 アバクシス， インコーポレイテッド エールリッヒア抗体の検出のためのペプチド、装置、および方法
KR101256628B1 (ko) 2009-11-24 2013-04-19 한국생명공학연구원 나노입자를 이용한 미생물의 고속 검출방법
US9308582B2 (en) 2009-12-24 2016-04-12 Yi Sun Solution stable and chemically reactive metallic nanoparticles
EP2354792A1 (en) 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
JP5728006B2 (ja) 2010-05-28 2015-06-03 国立大学法人東京工業大学 金属微粒子複合体及びその製造方法
JP5822239B2 (ja) * 2010-12-08 2015-11-24 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法
CN102103145B (zh) 2011-02-24 2013-01-16 南京基蛋生物科技有限公司 一种双放大系统的胶体金试纸条及其制备方法
US8697129B2 (en) 2011-03-02 2014-04-15 Imra America, Inc. Stable colloidal gold nanoparticles with controllable surface modification and functionalization
WO2012125693A2 (en) 2011-03-15 2012-09-20 Northwestern University Multifunctional metal nanoparticles having a polydopamine-based surface and methods of making and using the same
US20130230717A1 (en) 2011-09-02 2013-09-05 Washington University In St. Louis Copper nanostructures and methods for their preparation
US8758772B2 (en) 2011-11-04 2014-06-24 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
US9823246B2 (en) * 2011-12-28 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon
US20130189793A1 (en) 2012-01-20 2013-07-25 Wei Qian Stable Colloidal Suspensions Of Gold Nanoconjugates And The Method For Preparing The Same
WO2013116513A2 (en) 2012-01-31 2013-08-08 American University Of Cairo (Auc) Direct detection of disease biomarkers in clinical specimens using cationic nanoparticle-based assays & versatile and green methods forsynthesis of anisotropic silver nanostructures
EP2625966A1 (en) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof
TWI435843B (zh) 2012-04-27 2014-05-01 Univ Nat Taiwan 奈米顆粒的製造方法
TW201408690A (zh) * 2012-05-05 2014-03-01 Academia Sinica 二氨基苯甲酸或鄰苯二胺共軛的胜肽作為功能性的醣類標幟劑
JP6325552B2 (ja) 2012-10-11 2018-05-16 ナノコンポジックス，インコーポレイテッド 銀ナノプレート組成物および方法
WO2014059274A1 (en) * 2012-10-11 2014-04-17 Abaxis, Inc. Peptides, devices, and methods for the detection of ehrlichia antibodies
US9441301B2 (en) 2012-12-06 2016-09-13 Nanyang Technological University Method for forming a bimetallic core-shell nanostructure
JP6505076B2 (ja) 2013-03-14 2019-04-24 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ Ｈｃｖ抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物
EP2970947A4 (en) 2013-03-14 2016-10-12 Abbott Lab RECOMBINANT HCV NS3 ANTIGENS AND THEIR MUTANTS FOR ENHANCED ANTIBODY DETECTION
WO2014197222A1 (en) 2013-06-05 2014-12-11 Purdue Research Foundation Titanium nitride plasmonic nanoparticles for clinical therapeutic applications
WO2015017285A2 (en) 2013-07-30 2015-02-05 Bio-Rad Laboratories, Inc. Multiplex blocker beads for immunoassays
TW201538959A (zh) 2014-02-26 2015-10-16 Lamdagen Corp 用於增強分析靈敏度之數位局域表面電漿子共振（ｌｓｐｒ）
WO2015160923A1 (en) 2014-04-15 2015-10-22 Rutgers, The State University Of New Jersey Gold nanostar substrates for sers sensing in the femtomolar regime
WO2016007942A1 (en) 2014-07-11 2016-01-14 Northwestern University Synthesis of uniform anisotropic nanoparticles
JP5867890B1 (ja) 2014-08-01 2016-02-24 株式会社ビークル 免疫学的測定法に用いられるウイルス様粒子、それに用いられるブロッキング剤、及びこれらを含むキット
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
KR20170128342A (ko) 2015-02-19 2017-11-22 이오니카 사이언시즈 감염성 질병을 검출하기 위한 시약 및 방법
WO2016170183A1 (en) 2015-04-24 2016-10-27 Pharmadiagnostics Nv Improved method of measuring an interaction between molecules
DK3331818T3 (da) 2015-08-04 2024-08-12 Zoetis Services Llc Signalforstærkning i opløsningsbaserede plasmoniske assays med specifkke bindingspartnere
CA3051465A1 (en) 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100062545A1 (en) * 2005-06-15 2010-03-11 University Of Maryland Biotechnology Institute Bioassays using plasmonic scattering from noble metal nanostructures
US20130034854A1 (en) * 2010-04-27 2013-02-07 Ventana Medical Systems, Inc. Antibody-Nanoparticle Conjugates and Methods for Making and Using Such Conjugates

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BOLDUC O.R. ET AL., "Advances in surface plasmon resonance sensing with nanoparticles and thin films: Nanomaterials, surface chemistry, and hybrid plasmonic techniques" ANAL. CHEM. (2011) vol. 83, no. 21, pages 8057-8062 *
CUI Y. ET AL., "Synthesis of AgcoreAushell Bimetallic Nanoparticles for Immunoassay Based on Surface Enhanced Raman Spectroscopy", J. PHYS. CHEM. B, (2006-02-04), vol. 110, pages 4002-4006 *
CUI Y. ET AL., "Synthesis of AgcoreAushell Bimetallic Nanoparticles for Immunoassay Based on Surface-Enhanced Raman Spectroscopy", J. PHYS. CHEM. B, (2006-02-04), vol. 110, pages 4002-4006 *
DONG P. ET AL., "Ultrathin gold-shell coated silver nanoparticles onto a glass platform for improvement of plasmonic sensors", ACS APPL. MATER. INTERFACES, (2013-03-11), vol. 5, no. 7, pages 2392 - 2399 *
HAES A. ET AL., "Nanoscale plasmonics begins to unravel Alzheimer’s disease", LASER FOCUS WORLD, (2005-06-01) *

Also Published As

Publication number Publication date
BR112017002603A8 (pt) 2023-03-14
ES2888230T3 (es) 2022-01-03
EP3180619B1 (en) 2021-07-14
AU2015301632A1 (en) 2017-03-02
JP2022008384A (ja) 2022-01-13
SG10201901240TA (en) 2019-03-28
KR20230025925A (ko) 2023-02-23
WO2016025703A2 (en) 2016-02-18
US10488409B2 (en) 2019-11-26
KR20170040331A (ko) 2017-04-12
JP2017524140A (ja) 2017-08-24
IL280263B (en) 2022-05-01
EP3943943A1 (en) 2022-01-26
IL280263A (en) 2021-03-01
CA2957134C (en) 2023-09-05
PL3180619T3 (pl) 2021-12-13
CA3209879A1 (en) 2016-02-18
EP3180619A2 (en) 2017-06-21
BR112017002603A2 (pt) 2018-07-17
AU2021202253A1 (en) 2021-05-06
AU2021202253B2 (en) 2023-12-07
IL300266A (en) 2023-03-01
IL300266B1 (en) 2025-10-01
MX2017001905A (es) 2017-04-27
CN112415192B (zh) 2023-12-01
JP7793564B2 (ja) 2026-01-05
AU2023270256A1 (en) 2023-12-07
AU2023270256B2 (en) 2026-02-12
NZ728879A (en) 2024-08-30
PT3180619T (pt) 2021-09-20
IL300266B2 (en) 2026-02-01
IL291833A (en) 2022-06-01
EP3180619A4 (en) 2018-01-03
WO2016025703A3 (en) 2016-09-29
HUE056514T2 (hu) 2022-02-28
TW201614219A (en) 2016-04-16
IL250564A0 (en) 2017-03-30
US20200150115A1 (en) 2020-05-14
CN106796228A (zh) 2017-05-31
CA2957134A1 (en) 2016-02-18
US20220074934A1 (en) 2022-03-10
JP6945445B2 (ja) 2021-10-06
US11209430B2 (en) 2021-12-28
CN106796228B (zh) 2020-11-06
IL291833B2 (en) 2023-07-01
SG11201700864WA (en) 2017-03-30
US20160047804A1 (en) 2016-02-18
DK3180619T3 (da) 2021-09-13
JP2023067953A (ja) 2023-05-16
KR102787948B1 (ko) 2025-03-31
MX2022013567A (es) 2022-11-30
JP7240460B2 (ja) 2023-03-15
IL250564B (en) 2021-02-28
CN112415192A (zh) 2021-02-26
TWI691716B (zh) 2020-04-21
ZA201700873B (en) 2020-06-24
KR102497598B1 (ko) 2023-02-09
IL291833B1 (en) 2023-03-01

Similar Documents

Publication Publication Date Title
AU2023270256B2 (en) Signal amplification in plasmonic specific-binding partner assays
US11614447B2 (en) Signal amplification in solution-based plasmonic specific-binding partner assays
WO2016187588A1 (en) Plasmonic nanoparticles and lspr-based assays
HK40064559A (en) Signal amplification in plasmonic specific-binding partner assays
BR112017002603B1 (pt) Dispositivo de detecção de analito e método de detectar um analito alvo em uma amostra

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: ZOETIS SERVICES LLC

Free format text: FORMER APPLICANT(S): ABAXIS, INC.

FGA Letters patent sealed or granted (standard patent)