AU2015222805B2 - Treatment of conditions associated with hyperinsulinaemia - Google Patents
Treatment of conditions associated with hyperinsulinaemia Download PDFInfo
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- AU2015222805B2 AU2015222805B2 AU2015222805A AU2015222805A AU2015222805B2 AU 2015222805 B2 AU2015222805 B2 AU 2015222805B2 AU 2015222805 A AU2015222805 A AU 2015222805A AU 2015222805 A AU2015222805 A AU 2015222805A AU 2015222805 B2 AU2015222805 B2 AU 2015222805B2
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- AJZGFFKDLABHDD-UHFFFAOYSA-N thiazinane Chemical group C1CCSNC1 AJZGFFKDLABHDD-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
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- Engineering & Computer Science (AREA)
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- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
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- Physiology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201462054620P | 2014-09-24 | 2014-09-24 | |
| US62/054,620 | 2014-09-24 | ||
| PCT/US2015/018118 WO2015131113A1 (en) | 2014-02-28 | 2015-02-27 | Treatment of conditions associated with hyperinsulinaemia |
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| EP (1) | EP3110424A1 (enExample) |
| JP (2) | JP2017506666A (enExample) |
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| WO (1) | WO2015131113A1 (enExample) |
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| CA2799403C (en) | 2010-05-14 | 2020-01-21 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating leukemia |
| HUE031073T2 (en) | 2010-05-14 | 2017-06-28 | Dana Farber Cancer Inst Inc | Thieno triazolo-diazepine compounds for the treatment of neoplasia |
| RU2016122654A (ru) | 2013-11-08 | 2017-12-14 | Дана-Фарбер Кэнсер Инститьют, Инк. | Комбинированная терапия злокачественной опухоли с использованием ингибиторов бромодоменового и экстратерминального (вет) белка |
| US10150756B2 (en) | 2014-01-31 | 2018-12-11 | Dana-Farber Cancer Institute, Inc. | Diaminopyrimidine benzenesulfone derivatives and uses thereof |
| US10793571B2 (en) | 2014-01-31 | 2020-10-06 | Dana-Farber Cancer Institute, Inc. | Uses of diazepane derivatives |
| CA2940472A1 (en) | 2014-02-28 | 2015-09-03 | Tensha Therapeutics, Inc. | Treatment of conditions associated with hyperinsulinaemia |
| EA033325B1 (ru) | 2014-10-27 | 2019-09-30 | Тэнша Терапеутикс, Инк. | Ингибиторы бромодомена |
| AU2016283020A1 (en) | 2015-06-26 | 2018-01-04 | Tensha Therapeutics, Inc. | Treatment of nut midline carcinoma |
| CN108472300A (zh) | 2015-09-11 | 2018-08-31 | 达纳-法伯癌症研究所股份有限公司 | 氰基噻吩并三唑并二氮杂环庚三烯及其用途 |
| KR20180051576A (ko) * | 2015-09-11 | 2018-05-16 | 다나-파버 캔서 인스티튜트 인크. | 아세트아미드 티에노트리아졸로디아제핀 및 그의 용도 |
| PE20181298A1 (es) | 2015-11-25 | 2018-08-07 | Dana Farber Cancer Inst Inc | Inhibidores de bromodominio bivalentes y usos de los mismos |
| CN110088095A (zh) * | 2016-12-16 | 2019-08-02 | 豪夫迈·罗氏有限公司 | 用于制备二氮杂*衍生物的方法 |
| CN111094263A (zh) * | 2017-09-14 | 2020-05-01 | 豪夫迈·罗氏有限公司 | 可用于制造药物的新化合物 |
| JP2021527136A (ja) | 2018-06-13 | 2021-10-11 | ディブリー・アーゲー | 縮合トリアゼピン誘導体の調製及びｂｅｔ阻害剤としてのその使用 |
| CN111253871A (zh) * | 2020-03-13 | 2020-06-09 | 东莞市永益诚电子有限公司 | 一种钢化膜及其制备方法 |
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| WO2011143651A1 (en) * | 2010-05-14 | 2011-11-17 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for modulating metabolism |
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| EP0368175A1 (de) | 1988-11-06 | 1990-05-16 | Boehringer Ingelheim Kg | 3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin. |
| EP0387613A1 (de) | 1989-03-03 | 1990-09-19 | Boehringer Ingelheim Kg | Neue Thienodiazepine |
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- 2015-02-27 JP JP2016554661A patent/JP2017506666A/ja not_active Withdrawn
- 2015-02-27 CN CN201580010875.2A patent/CN106456653A/zh active Pending
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| JP2017506666A (ja) | 2017-03-09 |
| MX2016011160A (es) | 2017-04-27 |
| RU2016138027A3 (enExample) | 2018-10-29 |
| RU2016138027A (ru) | 2018-04-03 |
| US20170209461A1 (en) | 2017-07-27 |
| AU2015222805A1 (en) | 2016-09-15 |
| RU2722179C2 (ru) | 2020-05-28 |
| SG11201607108XA (en) | 2016-09-29 |
| EP3110424A1 (en) | 2017-01-04 |
| KR20160130778A (ko) | 2016-11-14 |
| WO2015131113A1 (en) | 2015-09-03 |
| JP6629947B2 (ja) | 2020-01-15 |
| CA2940472A1 (en) | 2015-09-03 |
| IL247354B (en) | 2020-06-30 |
| IL247354A0 (en) | 2016-11-30 |
| JP2019059751A (ja) | 2019-04-18 |
| CN106456653A (zh) | 2017-02-22 |
| MX377534B (es) | 2025-03-10 |
| US10925881B2 (en) | 2021-02-23 |
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