AU2014329421B2 - Stabilized efinaconazole compositions - Google Patents
Stabilized efinaconazole compositions Download PDFInfo
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- AU2014329421B2 AU2014329421B2 AU2014329421A AU2014329421A AU2014329421B2 AU 2014329421 B2 AU2014329421 B2 AU 2014329421B2 AU 2014329421 A AU2014329421 A AU 2014329421A AU 2014329421 A AU2014329421 A AU 2014329421A AU 2014329421 B2 AU2014329421 B2 AU 2014329421B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361886569P | 2013-10-03 | 2013-10-03 | |
| US61/886,569 | 2013-10-03 | ||
| US201461922867P | 2014-01-01 | 2014-01-01 | |
| US61/922,867 | 2014-01-01 | ||
| PCT/US2014/058911 WO2015051183A1 (en) | 2013-10-03 | 2014-10-02 | Stabilized efinaconazole compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2014329421A1 AU2014329421A1 (en) | 2016-04-07 |
| AU2014329421B2 true AU2014329421B2 (en) | 2018-08-02 |
Family
ID=52777446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014329421A Active AU2014329421B2 (en) | 2013-10-03 | 2014-10-02 | Stabilized efinaconazole compositions |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9662394B2 (enExample) |
| EP (1) | EP3052487B1 (enExample) |
| JP (3) | JP6516759B2 (enExample) |
| KR (1) | KR102320051B1 (enExample) |
| CN (2) | CN105683184B (enExample) |
| AU (1) | AU2014329421B2 (enExample) |
| CA (1) | CA2924748C (enExample) |
| IL (1) | IL244850B (enExample) |
| MX (1) | MX363386B (enExample) |
| MY (1) | MY179756A (enExample) |
| PH (1) | PH12016500586B1 (enExample) |
| SG (1) | SG11201602596UA (enExample) |
| WO (1) | WO2015051183A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090175810A1 (en) | 2008-01-03 | 2009-07-09 | Gareth Winckle | Compositions and methods for treating diseases of the nail |
| US8039494B1 (en) | 2010-07-08 | 2011-10-18 | Dow Pharmaceutical Sciences, Inc. | Compositions and methods for treating diseases of the nail |
| CN105683184B (zh) | 2013-10-03 | 2019-05-10 | 道尔医药科学公司 | 稳定的艾菲康唑组合物 |
| CA2931144C (en) | 2013-11-22 | 2020-02-04 | Dow Pharmaceutical Sciences, Inc. | Anti-infective methods, compositions, and devices |
| CN106918672B (zh) * | 2015-12-28 | 2021-02-09 | 中美华世通生物医药科技（武汉）有限公司 | 利用hplc测定艾氟康唑原料药及其制剂中有关物质的方法 |
| CN110087652A (zh) * | 2016-12-16 | 2019-08-02 | 株式会社钟化 | 甲癣治疗剂 |
| WO2019077163A2 (en) * | 2017-10-20 | 2019-04-25 | Galenicum Health S.L. | PHARMACEUTICAL DEVICE |
| JP7430070B2 (ja) * | 2019-02-08 | 2024-02-09 | 沢井製薬株式会社 | エフィナコナゾール含有爪外用液 |
| KR102060546B1 (ko) * | 2019-06-07 | 2019-12-30 | 주식회사 바이오빌리프 | 에피나코나졸을 함유하는 용액 형태의 국소 투여용 약학 조성물 |
| KR102352960B1 (ko) * | 2019-06-07 | 2022-01-19 | 주식회사 바이오빌리프 | 에피나코나졸을 함유하는 용액 형태의 국소 투여용 약학 조성물 |
| KR20210032672A (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 에피나코나졸을 함유하는 안정화된 약학 조성물 |
| WO2021054535A2 (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 킬레이트화제, 항산화제, 및 산의 조합을 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| WO2021054533A2 (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 산으로서 소르빈산을 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| KR20210032662A (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 킬레이트화제를 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| WO2021054531A2 (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 항산화제를 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| KR20210032665A (ko) * | 2019-09-17 | 2021-03-25 | 주식회사 바이오빌리프 | 킬레이트화제 및 항산화제의 조합을 포함하는 안정화된 에피나코나졸-함유 약학 조성물 |
| KR102266145B1 (ko) | 2019-09-26 | 2021-06-17 | 대봉엘에스 주식회사 | 비정질 에피나코나졸 고체 분산체 |
| JP2021054781A (ja) | 2019-09-26 | 2021-04-08 | デボン エルエス，リミテッド | 共結晶形エフィナコナゾール、及びその製造方法 |
| KR20220119363A (ko) | 2019-12-24 | 2022-08-29 | 가껭세이야꾸가부시기가이샤 | 에피나코나졸을 함유하는 의약 |
| KR102394599B1 (ko) * | 2020-03-19 | 2022-05-06 | 동아에스티 주식회사 | 에피나코나졸을 함유하는 국소 투여용 약학 조성물 |
| WO2021245206A1 (en) | 2020-06-03 | 2021-12-09 | The Materia Company Limited | Topical solution of efinaconazole with high subungual penetration |
| JP7664026B2 (ja) * | 2020-08-06 | 2025-04-17 | 沢井製薬株式会社 | エフィナコナゾール含有爪外用液 |
| EP3981402A4 (en) * | 2020-08-14 | 2022-08-10 | BL&H Co., Ltd. | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF RINGWORM |
| KR102729906B1 (ko) * | 2020-10-30 | 2024-11-14 | 주식회사 대웅제약 | 항진균제를 포함하는 안정화된 조성물 |
| KR102301743B1 (ko) | 2020-12-29 | 2021-09-13 | 대봉엘에스 주식회사 | 에피나코나졸 경구용 조성물 |
| US20240108613A1 (en) * | 2021-02-05 | 2024-04-04 | Acp Laboratories Llc | Topical composition for treating fungi forming on a user's body |
| KR102863832B1 (ko) * | 2021-05-04 | 2025-09-25 | 주식회사 제뉴원사이언스 | 에피나코나졸을 함유하는 액상 형태의 약학적 조성물 |
| WO2022235048A1 (ko) * | 2021-05-04 | 2022-11-10 | 주식회사 제뉴원사이언스 | 에피나코나졸을 함유하는 액상 형태의 약학적 조성물 |
| KR20230158920A (ko) | 2022-05-12 | 2023-11-21 | 주식회사한국파마 | 에피나코나졸을 함유하는 안정화된 국소투여용 약학 조성물 |
| KR102842759B1 (ko) | 2022-05-20 | 2025-08-06 | 주식회사한국파마 | 항진균제로서 에피나코나졸을 함유하는 약학 조성물 |
| KR102597564B1 (ko) * | 2023-03-03 | 2023-11-03 | 장병모 | 조갑 및 피부 백선의 예방 또는 치료용 약학적 조성물 |
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| US6042845A (en) * | 1994-12-22 | 2000-03-28 | Johnson & Johnson Consumer Products, Inc. | Anti fungal treatment of nails |
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| DE41306C (de) | A. STORIE VAN DEN ABEELE in Brügge, Belgien | Tabak-Trockner | ||
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| DE3106635A1 (de) | 1981-02-23 | 1982-09-09 | Bayer Ag | Antimykotisches mittel mit hoher wirkstoff-freisetzung in form von stiften |
| US4384589A (en) | 1981-07-27 | 1983-05-24 | American Cyanamid Company | Novel liquid delivery system for toiletries |
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| AU599064B2 (en) | 1985-11-04 | 1990-07-12 | Dermatological Products Of Texas | Film-forming, pharmaceutical vehicles for application of medicaments to nails, pharmaceutical compositions based on those vehicles, and methods of using same |
| DE3544983A1 (de) | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
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