AU2014266830B2 - Methods for engineering allogeneic and highly active T cell for immunotherapy - Google Patents

Methods for engineering allogeneic and highly active T cell for immunotherapy Download PDF

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AU2014266830B2
AU2014266830B2 AU2014266830A AU2014266830A AU2014266830B2 AU 2014266830 B2 AU2014266830 B2 AU 2014266830B2 AU 2014266830 A AU2014266830 A AU 2014266830A AU 2014266830 A AU2014266830 A AU 2014266830A AU 2014266830 B2 AU2014266830 B2 AU 2014266830B2
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cells
cell
tcr
val
leu
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AU2014266830A1 (en
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Roman Galetto
Agnes Gouble
Stephanie Grosse
Laurent Poirot
Andrew Scharenberg
Cecile Schiffer-Mannioui
Julianne Smith
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Cellectis SA
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Cellectis SA
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/32—T-cell receptors [TCR]
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AU2014266830A 2013-05-13 2014-05-13 Methods for engineering allogeneic and highly active T cell for immunotherapy Active AU2014266830B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
AUPCT/US2013/040766 2013-05-13
US13/892,805 2013-05-13
AUPCT/US2013/040755 2013-05-13
PCT/US2013/040766 WO2013176916A1 (en) 2012-05-25 2013-05-13 Use of pre t alpha or functional variant thereof for expanding tcr alpha deficient t cells
PCT/US2013/040755 WO2013176915A1 (en) 2012-05-25 2013-05-13 Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
US13/892,805 US11603539B2 (en) 2012-05-25 2013-05-13 Methods for engineering allogeneic and immunosuppressive resistant T cell for immunotherapy
US13/942,191 2013-07-15
US13/942,191 US20150017136A1 (en) 2013-07-15 2013-07-15 Methods for engineering allogeneic and highly active t cell for immunotherapy
PCT/IB2014/061409 WO2014184741A1 (en) 2013-05-13 2014-05-13 Methods for engineering allogeneic and highly active t cell for immunotheraphy

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AU2014266830A1 AU2014266830A1 (en) 2015-11-26
AU2014266830B2 true AU2014266830B2 (en) 2020-07-02

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KR (3) KR20210143926A (enExample)
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WO2013066438A2 (en) 2011-07-22 2013-05-10 President And Fellows Of Harvard College Evaluation and improvement of nuclease cleavage specificity
US20150017136A1 (en) * 2013-07-15 2015-01-15 Cellectis Methods for engineering allogeneic and highly active t cell for immunotherapy
US20230050345A1 (en) * 2013-05-13 2023-02-16 Cellectis Methods for engineering allogeneic and highly active t cell for immunotheraphy
US20150044192A1 (en) 2013-08-09 2015-02-12 President And Fellows Of Harvard College Methods for identifying a target site of a cas9 nuclease
US9359599B2 (en) 2013-08-22 2016-06-07 President And Fellows Of Harvard College Engineered transcription activator-like effector (TALE) domains and uses thereof
US9388430B2 (en) 2013-09-06 2016-07-12 President And Fellows Of Harvard College Cas9-recombinase fusion proteins and uses thereof
US9340799B2 (en) 2013-09-06 2016-05-17 President And Fellows Of Harvard College MRNA-sensing switchable gRNAs
US9737604B2 (en) 2013-09-06 2017-08-22 President And Fellows Of Harvard College Use of cationic lipids to deliver CAS9
KR20230054509A (ko) 2013-11-07 2023-04-24 에디타스 메디신, 인코포레이티드 지배적인 gRNA를 이용하는 CRISPR-관련 방법 및 조성물
AU2014351871B2 (en) * 2013-11-22 2020-02-13 Cellectis Method for generating batches of allogeneic T-cells with averaged potency
US11053481B2 (en) 2013-12-12 2021-07-06 President And Fellows Of Harvard College Fusions of Cas9 domains and nucleic acid-editing domains
AU2014368383B2 (en) * 2013-12-20 2020-01-16 Cellectis Method of engineering multi-input signal sensitive T cell for immunotherapy
ES2740903T3 (es) 2014-03-19 2020-02-07 Cellectis Receptores antigénicos quiméricos específicos de CD123 para inmunoterapia del cáncer
AU2015298571B2 (en) 2014-07-30 2020-09-03 President And Fellows Of Harvard College Cas9 proteins including ligand-dependent inteins
EP4427809A3 (en) 2014-10-31 2024-12-04 The Trustees of The University of Pennsylvania Altering gene expression in car-t cells and uses thereof
CA2973529A1 (en) 2015-01-26 2016-08-04 Cellectis Cll1-specific multi-chain chimeric antigen receptor
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