AU2012303701B2 - System and method for locating and identifying functional nerves innervating wall of arteries and catheters for same - Google Patents

System and method for locating and identifying functional nerves innervating wall of arteries and catheters for same Download PDF

Info

Publication number
AU2012303701B2
AU2012303701B2 AU2012303701A AU2012303701A AU2012303701B2 AU 2012303701 B2 AU2012303701 B2 AU 2012303701B2 AU 2012303701 A AU2012303701 A AU 2012303701A AU 2012303701 A AU2012303701 A AU 2012303701A AU 2012303701 B2 AU2012303701 B2 AU 2012303701B2
Authority
AU
Australia
Prior art keywords
renal
catheter
nerve
ablation
energy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2012303701A
Other languages
English (en)
Other versions
AU2012303701A1 (en
Inventor
Jie Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SyMap Medical Suzhou Ltd
Original Assignee
SyMap Medical Suzhou Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SyMap Medical Suzhou Ltd filed Critical SyMap Medical Suzhou Ltd
Publication of AU2012303701A1 publication Critical patent/AU2012303701A1/en
Application granted granted Critical
Publication of AU2012303701B2 publication Critical patent/AU2012303701B2/en
Assigned to SYMAP HOLDING LIMITED reassignment SYMAP HOLDING LIMITED Request for Assignment Assignors: SYMAP MEDICAL LIMITED
Assigned to SYMAP MEDICAL (SUZHOU), LTD reassignment SYMAP MEDICAL (SUZHOU), LTD Request for Assignment Assignors: SYMAP HOLDING LIMITED
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/0036Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room including treatment, e.g., using an implantable medical device, ablating, ventilating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/0215Measuring pressure in heart or blood vessels by means inserted into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/20Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/201Assessing renal or kidney functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4833Assessment of subject's compliance to treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4887Locating particular structures in or on the body
    • A61B5/4893Nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852Catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852Catheters
    • A61B5/6853Catheters with a balloon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N7/02Localised ultrasound hyperthermia
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16ZINFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00Subject matter not provided for in other main groups of this subclass
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • A61B2018/00404Blood vessels other than those in or around the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434Neural system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505Urinary tract
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505Urinary tract
    • A61B2018/00511Kidney
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00642Sensing and controlling the application of energy with feedback, i.e. closed loop control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00702Power or energy
    • A61B2018/00708Power or energy switching the power on or off
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00839Bioelectrical parameters, e.g. ECG, EEG
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00875Resistance or impedance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0212Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024Measuring pulse rate or heart rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0538Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114Cardiac control, e.g. by vagal stimulation
    • A61N1/36117Cardiac control, e.g. by vagal stimulation for treating hypertension
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0004Applications of ultrasound therapy
    • A61N2007/0021Neural system treatment
    • A61N2007/003Destruction of nerve tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Electromagnetism (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Surgical Instruments (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Laser Surgery Devices (AREA)
  • Electrotherapy Devices (AREA)
AU2012303701A 2011-08-26 2012-08-24 System and method for locating and identifying functional nerves innervating wall of arteries and catheters for same Active AU2012303701B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161527893P 2011-08-26 2011-08-26
US61/527,893 2011-08-26
US201261609565P 2012-03-12 2012-03-12
US61/609,565 2012-03-12
PCT/IB2012/054310 WO2013030743A1 (en) 2011-08-26 2012-08-24 System and method for locating and identifying functional nerves innervating wall of arteries and catheters for same

Publications (2)

Publication Number Publication Date
AU2012303701A1 AU2012303701A1 (en) 2013-05-02
AU2012303701B2 true AU2012303701B2 (en) 2014-02-27

Family

ID=47755409

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2012303701A Active AU2012303701B2 (en) 2011-08-26 2012-08-24 System and method for locating and identifying functional nerves innervating wall of arteries and catheters for same
AU2012303696A Active AU2012303696B2 (en) 2011-08-26 2012-08-24 System and method for locating and identifying functional nerves innervating wall of arteries

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2012303696A Active AU2012303696B2 (en) 2011-08-26 2012-08-24 System and method for locating and identifying functional nerves innervating wall of arteries

Country Status (13)

Country Link
US (11) US9014821B2 (enExample)
EP (2) EP2747691B1 (enExample)
JP (3) JP6188159B2 (enExample)
KR (1) KR101862903B1 (enExample)
CN (2) CN103796604B (enExample)
AU (2) AU2012303701B2 (enExample)
CA (1) CA2846395C (enExample)
ES (2) ES2765011T3 (enExample)
IL (1) IL231127A (enExample)
RU (1) RU2638438C2 (enExample)
SG (2) SG2014013957A (enExample)
WO (2) WO2013030738A1 (enExample)
ZA (1) ZA201402085B (enExample)

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6702811B2 (en) 1999-04-05 2004-03-09 Medtronic, Inc. Ablation catheter assembly with radially decreasing helix and method of use
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
CN101076290B (zh) 2004-12-09 2011-11-23 铸造品股份有限公司 主动脉瓣修复
US20070021803A1 (en) 2005-07-22 2007-01-25 The Foundry Inc. Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction
WO2007136566A2 (en) 2006-05-19 2007-11-29 Prorhythm, Inc. Ablation device with optimized input power profile and method of using the same
CN105056408B (zh) * 2006-06-28 2018-09-25 美敦力Af卢森堡公司 用于热诱导的肾神经调制的系统
US8083685B2 (en) 2007-05-08 2011-12-27 Propep, Llc System and method for laparoscopic nerve detection
US11376061B2 (en) 2008-11-11 2022-07-05 Covidien Lp Energy delivery device and methods of use
US11998266B2 (en) 2009-10-12 2024-06-04 Otsuka Medical Devices Co., Ltd Intravascular energy delivery
AU2010313379B2 (en) 2009-10-30 2015-11-05 Recor Medical, Inc. Method and apparatus for treatment of hypertension through percutaneous ultrasound renal denervation
US9743884B2 (en) 2010-04-30 2017-08-29 J3G Spine, Llc Devices and methods for nerve mapping
US9028417B2 (en) 2010-10-18 2015-05-12 CardioSonic Ltd. Ultrasound emission element
US9566456B2 (en) 2010-10-18 2017-02-14 CardioSonic Ltd. Ultrasound transceiver and cooling thereof
WO2012052920A1 (en) 2010-10-18 2012-04-26 CardioSonic Ltd. Therapeutics reservoir
US8585601B2 (en) 2010-10-18 2013-11-19 CardioSonic Ltd. Ultrasound transducer
EP3100696B1 (en) 2010-10-25 2023-01-11 Medtronic Ardian Luxembourg S.à.r.l. Catheter apparatuses having multi-electrode arrays for renal neuromodulation
EP2632373B1 (en) 2010-10-25 2018-07-18 Medtronic Ardian Luxembourg S.à.r.l. System for evaluation and feedback of neuromodulation treatment
WO2012161875A1 (en) 2011-04-08 2012-11-29 Tyco Healthcare Group Lp Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
EP2701623B1 (en) 2011-04-25 2016-08-17 Medtronic Ardian Luxembourg S.à.r.l. Apparatus related to constrained deployment of cryogenic balloons for limited cryogenic ablation of vessel walls
US8909316B2 (en) 2011-05-18 2014-12-09 St. Jude Medical, Cardiology Division, Inc. Apparatus and method of assessing transvascular denervation
US8702619B2 (en) * 2011-08-26 2014-04-22 Symap Holding Limited Mapping sympathetic nerve distribution for renal ablation and catheters for same
US9820811B2 (en) 2011-08-26 2017-11-21 Symap Medical (Suzhou), Ltd System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same
US12295650B2 (en) * 2011-08-26 2025-05-13 Symap Medical (Suzhou), Ltd Device for mapping and ablating renal nerves distributed on the renal artery
US20190110704A1 (en) * 2017-10-06 2019-04-18 Symap Medical (Suzhou), Limited System and method for mapping the functional nerves innervating the wall of arteries, 3-d mapping and catheters for same
RU2638438C2 (ru) * 2011-08-26 2017-12-13 Симап Холдинг Лимитед Система и способ определения места расположения и идентификации функциональных нервов, иннервирующих стенку артерий, и катетеры для них
US9427579B2 (en) 2011-09-29 2016-08-30 Pacesetter, Inc. System and method for performing renal denervation verification
US9327123B2 (en) 2011-11-07 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Endovascular nerve monitoring devices and associated systems and methods
KR102067583B1 (ko) 2011-12-09 2020-01-17 메타벤션, 인크. 간 시스템의 치료적 신경조절
US9649064B2 (en) * 2012-01-26 2017-05-16 Autonomix Medical, Inc. Controlled sympathectomy and micro-ablation systems and methods
CA2865242A1 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg S.A.R.L. Biomarker sampling in the context of neuromodulation devices and associated systems and methods
US20150111918A1 (en) 2012-03-08 2015-04-23 Medtronic Ardian Luxembourg S.a.r.l Immune system neuromodulation and associated systems and methods
WO2013157011A2 (en) 2012-04-18 2013-10-24 CardioSonic Ltd. Tissue treatment
JP6134382B2 (ja) 2012-05-11 2017-05-24 メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ 腎神経変調療法のための多電極カテーテル組立体並びに関連するシステム及び方法
JP2013236662A (ja) * 2012-05-11 2013-11-28 Olympus Corp 神経刺激電極および神経刺激システム
US11357447B2 (en) 2012-05-31 2022-06-14 Sonivie Ltd. Method and/or apparatus for measuring renal denervation effectiveness
CN203138452U (zh) * 2012-08-24 2013-08-21 苏州信迈医疗器械有限公司 一种能够定位或识别位于血管壁内或外膜上的神经的仪器
US9770593B2 (en) 2012-11-05 2017-09-26 Pythagoras Medical Ltd. Patient selection using a transluminally-applied electric current
CN104902836B (zh) 2012-11-05 2017-08-08 毕达哥拉斯医疗有限公司 受控组织消融
US9095321B2 (en) 2012-11-21 2015-08-04 Medtronic Ardian Luxembourg S.A.R.L. Cryotherapeutic devices having integral multi-helical balloons and methods of making the same
US20150297151A1 (en) * 2012-12-10 2015-10-22 Koninklijke Philips N.V. Positioning tool
US20140303617A1 (en) * 2013-03-05 2014-10-09 Neuro Ablation, Inc. Intravascular nerve ablation devices & methods
US10716914B2 (en) 2013-03-12 2020-07-21 St. Jude Medical, Cardiology Division, Inc. Catheter system
US10328238B2 (en) 2013-03-12 2019-06-25 St. Jude Medical, Cardiology Division, Inc. Catheter system
EP2777741A3 (en) 2013-03-12 2015-01-21 St. Jude Medical, Cardiology Division, Inc. Catheter system
WO2014163990A1 (en) 2013-03-12 2014-10-09 Boston Scientific Scimed, Inc. Medical systems and methods for modulating nerves
US9510902B2 (en) 2013-03-13 2016-12-06 St. Jude Medical, Cardiology Division, Inc. Ablation catheters and systems including rotational monitoring means
CN106178294B (zh) 2013-03-14 2018-11-20 瑞蔻医药有限公司 一种血管内的基于超声波的消融系统
US8876813B2 (en) 2013-03-14 2014-11-04 St. Jude Medical, Inc. Methods, systems, and apparatus for neural signal detection
US9179974B2 (en) 2013-03-15 2015-11-10 Medtronic Ardian Luxembourg S.A.R.L. Helical push wire electrode
US9186212B2 (en) 2013-03-15 2015-11-17 St. Jude Medical, Cardiology Division, Inc. Feedback systems and methods utilizing two or more sites along denervation catheter
US10543037B2 (en) 2013-03-15 2020-01-28 Medtronic Ardian Luxembourg S.A.R.L. Controlled neuromodulation systems and methods of use
US9713490B2 (en) 2013-03-15 2017-07-25 St. Jude Medical, Cardiology Division, Inc. Ablation system, methods, and controllers
US9974477B2 (en) 2013-03-15 2018-05-22 St. Jude Medical, Cardiology Division, Inc. Quantification of renal denervation via alterations in renal blood flow pre/post ablation
EP2967728A1 (en) 2013-03-15 2016-01-20 St. Jude Medical, Cardiology Division, Inc. Ablation system, methods, and controllers
US9179973B2 (en) 2013-03-15 2015-11-10 St. Jude Medical, Cardiology Division, Inc. Feedback systems and methods for renal denervation utilizing balloon catheter
EP2988691B1 (en) 2013-04-25 2018-03-28 St. Jude Medical, Cardiology Division, Inc. Electrode assembly for catheter system
EP2991717A4 (en) 2013-05-02 2016-12-07 Douglas C Harrington DEVICES AND METHOD FOR DETECTING AND TREATING THE GANGLION AORTICORENALE
US10933259B2 (en) 2013-05-23 2021-03-02 CardioSonic Ltd. Devices and methods for renal denervation and assessment thereof
US20160128767A1 (en) 2013-06-05 2016-05-12 Metavention, Inc. Modulation of targeted nerve fibers
US9872728B2 (en) 2013-06-28 2018-01-23 St. Jude Medical, Cardiology Division, Inc. Apparatuses and methods for affixing electrodes to an intravascular balloon
US20150011991A1 (en) 2013-07-03 2015-01-08 St. Jude Medical, Cardiology Division, Inc. Electrode Assembly For Catheter System
US20150025524A1 (en) * 2013-07-18 2015-01-22 St. Jude Medical, Cardiology Division, Inc. Renal denervation monitoring and feedback apparatus, system and method
US20150025421A1 (en) * 2013-07-19 2015-01-22 Highland Instruments, Inc. Stimulation to guide physical therapy
US9326816B2 (en) 2013-08-30 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation systems having nerve monitoring assemblies and associated devices, systems, and methods
US9339332B2 (en) 2013-08-30 2016-05-17 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters with nerve monitoring features for transmitting digital neural signals and associated systems and methods
US20150073515A1 (en) 2013-09-09 2015-03-12 Medtronic Ardian Luxembourg S.a.r.I. Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods
US10433902B2 (en) 2013-10-23 2019-10-08 Medtronic Ardian Luxembourg S.A.R.L. Current control methods and systems
USD747491S1 (en) 2013-10-23 2016-01-12 St. Jude Medical, Cardiology Division, Inc. Ablation generator
USD914883S1 (en) 2013-10-23 2021-03-30 St. Jude Medical, Cardiology Division, Inc. Ablation generator
USD774043S1 (en) 2013-10-23 2016-12-13 St. Jude Medical, Cardiology Division, Inc. Display screen with graphical user interface for ablation generator
US10856936B2 (en) 2013-10-23 2020-12-08 St. Jude Medical, Cardiology Division, Inc. Electrode assembly for catheter system including thermoplastic-based struts
WO2015061034A1 (en) 2013-10-24 2015-04-30 St. Jude Medical, Cardiology Division, Inc. Flexible catheter shaft and method of manufacture
US10034705B2 (en) 2013-10-24 2018-07-31 St. Jude Medical, Cardiology Division, Inc. High strength electrode assembly for catheter system including novel electrode
US9913961B2 (en) 2013-10-24 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Flexible catheter shaft and method of manufacture
EP3062722B1 (en) 2013-10-28 2019-03-20 St. Jude Medical, Cardiology Division, Inc. Electrode assembly for catheter system including interlinked struts
JP2015089419A (ja) * 2013-11-05 2015-05-11 株式会社リバーセイコー 医療用アブレーションカテーテルおよびその製造方法
US9861433B2 (en) 2013-11-05 2018-01-09 St. Jude Medical, Cardiology Division, Inc. Helical-shaped ablation catheter and methods of use
US20170056104A1 (en) * 2014-03-10 2017-03-02 Mayo Foundation For Medical Education And Research Hemodynamic measurement devices and techniques
US9579149B2 (en) 2014-03-13 2017-02-28 Medtronic Ardian Luxembourg S.A.R.L. Low profile catheter assemblies and associated systems and methods
US9999463B2 (en) 2014-04-14 2018-06-19 NeuroMedic, Inc. Monitoring nerve activity
US12350050B2 (en) 2014-04-14 2025-07-08 Recor Medical, Inc. Intraluminal microneurography probes and related systems and methods
US20170027460A1 (en) 2015-07-29 2017-02-02 NeuroMedic, Inc. Intraluminal microneurography probe
CN106232043B (zh) 2014-04-24 2019-07-23 美敦力阿迪安卢森堡有限公司 具有编织轴的神经调节导管以及相关的系统和方法
EP2937053A1 (en) 2014-04-24 2015-10-28 St. Jude Medical, Cardiology Division, Inc. Ablation systems including pulse rate detector and feedback mechanism and methods of use
US10791931B2 (en) 2015-02-04 2020-10-06 Thornhill Scientific Inc. Imaging reductions in cerebrovascular reactivity
US11880989B2 (en) 2014-04-25 2024-01-23 Thornhill Scientific Inc. Imaging abnormalities in vascular response
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
WO2015161363A1 (en) * 2014-04-25 2015-10-29 Joseph Fisher Imaging abnormalities in vascular response
US10709490B2 (en) 2014-05-07 2020-07-14 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
CN106659531A (zh) * 2014-05-07 2017-05-10 毕达哥拉斯医疗有限公司 受控组织消融技术
US10987050B2 (en) 2014-07-21 2021-04-27 ProPep Surgical, LLC System and method for laparoscopic nerve identification, nerve location marking, and nerve location recognition
WO2016033543A1 (en) * 2014-08-28 2016-03-03 Medtronic Ardian Luxembourg S.A.R.L. Methods for assessing efficacy of renal neuromodulation and associated systems and devices
WO2016054379A1 (en) 2014-10-01 2016-04-07 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for evaluating neuromodulation therapy via hemodynamic responses
US10925579B2 (en) 2014-11-05 2021-02-23 Otsuka Medical Devices Co., Ltd. Systems and methods for real-time tracking of a target tissue using imaging before and during therapy delivery
WO2016084081A2 (en) * 2014-11-26 2016-06-02 Sonievie Ltd. Devices and methods for pulmonary hypertension treatment
EP3226795B1 (en) 2014-12-03 2020-08-26 Metavention, Inc. Systems for modulating nerves or other tissue
US10667736B2 (en) 2014-12-17 2020-06-02 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing sympathetic nervous system tone for neuromodulation therapy
US10376308B2 (en) 2015-02-05 2019-08-13 Axon Therapies, Inc. Devices and methods for treatment of heart failure by splanchnic nerve ablation
US10383685B2 (en) 2015-05-07 2019-08-20 Pythagoras Medical Ltd. Techniques for use with nerve tissue
WO2017012907A1 (en) 2015-07-21 2017-01-26 Koninklijke Philips N.V. System for stimulating renal nerves
WO2017024055A1 (en) 2015-08-03 2017-02-09 Boston Scientific Scimed, Inc. Steerable tissue mapping and ablation device
JP6894890B2 (ja) * 2015-09-24 2021-06-30 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 自動センサ認識
US11020166B2 (en) * 2015-09-25 2021-06-01 Gyrus Acmi, Inc. Multifunctional medical device
EP3397334A4 (en) * 2015-10-06 2019-08-07 Halcyon Medical, Inc. GANGLION-AORTICORENALE DETECTION
US10130420B2 (en) * 2015-10-08 2018-11-20 Biosense Webster (Israel) Ltd. Catheter with membraned spines for pulmonary vein isolation
US10207110B1 (en) 2015-10-13 2019-02-19 Axon Therapies, Inc. Devices and methods for treatment of heart failure via electrical modulation of a splanchnic nerve
AU2016338856B2 (en) * 2015-10-14 2021-01-28 President And Fellows Of Harvard College Automatically classifying animal behavior
SG11201804191TA (en) * 2015-12-01 2018-06-28 Symap Medical Suzhou Ltd System and method for mapping functional nerves innervating wall of arteries,3-d mapping and catheters for same
US10624554B2 (en) * 2016-01-14 2020-04-21 Biosense Webster (Israel) Ltd. Non-overlapping loop-type or spline-type catheter to determine activation source direction and activation source type
US20170202614A1 (en) * 2016-01-20 2017-07-20 Rainbow Medical Ltd. Catheter guidance and procedure planning
JP6419099B2 (ja) * 2016-01-20 2018-11-07 日本ライフライン株式会社 焼灼用針装置、高周波焼灼治療システムおよび化学焼灼治療システム
EP3457975A2 (en) * 2016-05-18 2019-03-27 Pythagoras Medical Ltd. Helical catheter
WO2017203380A1 (en) * 2016-05-24 2017-11-30 Ecole Polytechnique Federale De Lausanne (Epfl) Endoluminal nerve modulation device and methods for using thereof
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
CN106109006B (zh) * 2016-07-18 2019-01-22 谢贇 经冠状静脉系统的射频消融导管
CN109843160B (zh) 2016-07-29 2022-04-15 阿克松疗法公司 通过脏神经消融术治疗心脏衰竭的装置、系统和方法
US10231784B2 (en) 2016-10-28 2019-03-19 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for optimizing perivascular neuromodulation therapy using computational fluid dynamics
US20180250054A1 (en) * 2017-03-06 2018-09-06 Pythagoras Medical Ltd. Ultrasound transucer with electrode feelers
US20200238107A1 (en) 2017-03-20 2020-07-30 Sonie Vie Ltd. Pulmonary hypertension treatment method and/or system
CN107468237B (zh) * 2017-08-24 2024-02-13 郭铮蔚 一种多功能神经监测探查系统及其实现方法
WO2019118976A1 (en) 2017-12-17 2019-06-20 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
RU179539U1 (ru) * 2018-01-11 2018-05-17 Федеральное государственное бюджетное образовательное учреждение высшего образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Зонд для остановки кровотечений из вен пищевода
US12082917B2 (en) 2018-01-24 2024-09-10 Medtronic Ireland Manufacturing Unlimited Company Systems, devices, and methods for assessing efficacy of renal neuromodulation therapy
EP4406567A3 (en) 2018-01-26 2024-10-09 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
WO2019169446A1 (en) * 2018-03-09 2019-09-12 The University Of Sydney Response monitoring
CN112367935A (zh) * 2018-06-13 2021-02-12 赫拉库雷医疗有限公司 组织块的选择性切除和检测
US10980599B2 (en) 2018-07-05 2021-04-20 Avent, Inc. System and method for adjusting available power per probe during an ablation procedure
US11633120B2 (en) 2018-09-04 2023-04-25 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing efficacy of renal neuromodulation therapy
US11832965B2 (en) 2018-10-06 2023-12-05 Symap Medical (Suzhou), Limited System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same
CN112955974B (zh) * 2018-10-26 2025-01-14 皇家飞利浦有限公司 用于确定肾脏去神经支配处置反应指数的设备、系统和方法
CN109528297A (zh) * 2018-10-29 2019-03-29 四川大学华西医院 一种可进行喉返神经监测的消融针及监测系统
CN112168335A (zh) * 2019-01-30 2021-01-05 苏州信迈医疗器械有限公司 一种具有防止重复消融功能的射频消融仪
US11607275B2 (en) 2019-05-20 2023-03-21 Medtronic Ireland Manufacturing Unlimited Company Selection of hypertensive patients for treatment with renal denervation
US20200376262A1 (en) * 2019-05-30 2020-12-03 Boston Scientific Neuromodulation Corporation Systems and methods for making and using implantable electrical/optical stimulation leads and systems
WO2020257763A1 (en) 2019-06-20 2020-12-24 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
CN114340720B (zh) * 2019-08-29 2024-12-20 迪普库雷公司 用于包围体内的管的电极装置及其方法
US12179013B2 (en) 2019-08-29 2024-12-31 Deepqure Inc. Electrode device for wrapping vessel in the body and method therefor
CN112336445B (zh) * 2019-12-26 2021-11-26 上海微创电生理医疗科技股份有限公司 一种消融系统及其神经探测设备
WO2021146724A1 (en) 2020-01-17 2021-07-22 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
CN111643727B (zh) * 2020-06-02 2021-02-09 中国人民解放军总医院 具有电磁感应功能的神经导管及其使用方法和制备方法
WO2022025783A1 (ru) 2020-07-28 2022-02-03 Общество с ограниченной ответственностью "Ангиолайф" Применения комбинации генов ангиогенных и нейротрофических факторов
CN111743621A (zh) * 2020-07-30 2020-10-09 中国人民解放军空军军医大学 一种用于食道肿瘤组织不可逆电穿孔治疗的侵入式电极
US12419662B2 (en) 2021-02-19 2025-09-23 Otsuka Medical Devices Co., Ltd. Selectively insulated ultrasound transducers
CN113133745A (zh) * 2021-04-30 2021-07-20 中南大学湘雅二医院 一种交感神经链神经纤维定位标测装置
IL309961A (en) 2021-07-05 2024-03-01 Veinway Ltd Vessel blockage passing
US12440165B2 (en) 2021-07-28 2025-10-14 Otsuka Medical Devices Co., Ltd. Catheter for neural measurements and treatment and related systems and methods
WO2023031053A1 (en) * 2021-08-30 2023-03-09 Implantica Patent Ltd Treatment of hypertension
EP4395673A1 (en) * 2021-08-31 2024-07-10 Medtronic Ireland Manufacturing Unlimited Company Cryotherapeutic treatment devices
CN114569237A (zh) * 2022-02-09 2022-06-03 高传玉 去肾动脉交感神经术用射频消融系统及射频消融钳
US20250195041A1 (en) * 2022-03-02 2025-06-19 Zeptomed, Inc. Method for Evaluating Outcome of Renal Denervation
CN114767263A (zh) * 2022-04-12 2022-07-22 杭州睿笛生物科技有限公司 一种肾动脉消融系统
EP4424260B1 (en) * 2023-02-28 2025-09-17 Medtronic Ireland Manufacturing Unlimited Company Heurisitic selection of denervation therapy
WO2025247725A1 (en) * 2024-05-30 2025-12-04 Medtronic Ireland Manufacturing Unlimited Company Predictive stimulation and ablation therapy for renal denervation
CN120078509B (zh) * 2025-04-27 2025-07-04 中国人民解放军联勤保障部队第九〇〇医院 基于智能数据分析的个性化心律失常射频消融系统

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6292695B1 (en) * 1998-06-19 2001-09-18 Wilton W. Webster, Jr. Method and apparatus for transvascular treatment of tachycardia and fibrillation
WO2008061150A2 (en) * 2006-11-14 2008-05-22 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation or denervation

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4323585A1 (de) 1993-07-14 1995-01-19 Delma Elektro Med App Bipolares Hochfrequenz-Chirurgieinstrument
US6090104A (en) * 1995-06-07 2000-07-18 Cordis Webster, Inc. Catheter with a spirally wound flat ribbon electrode
US5718241A (en) * 1995-06-07 1998-02-17 Biosense, Inc. Apparatus and method for treating cardiac arrhythmias with no discrete target
SE507465C2 (sv) * 1995-07-07 1998-06-08 Lund Instr Ab Anordning för värmebehandling av prostatavävnad
WO1997012548A1 (en) 1995-10-06 1997-04-10 Cordis Webster, Inc. Split tip electrode catheter
US5836857A (en) 1997-07-28 1998-11-17 Fred C. Jennings Apparatus and method for applying lateral force to body joints
US6171275B1 (en) * 1998-12-03 2001-01-09 Cordis Webster, Inc. Irrigated split tip electrode catheter
US20070066972A1 (en) 2001-11-29 2007-03-22 Medwaves, Inc. Ablation catheter apparatus with one or more electrodes
US20020082594A1 (en) * 1999-10-02 2002-06-27 Cary Hata Injectable biomaterial and methods for use thereof
US6564096B2 (en) 2001-02-28 2003-05-13 Robert A. Mest Method and system for treatment of tachycardia and fibrillation
US7778703B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Selective nerve fiber stimulation for treating heart conditions
US8974446B2 (en) 2001-10-11 2015-03-10 St. Jude Medical, Inc. Ultrasound ablation apparatus with discrete staggered ablation zones
US20070135875A1 (en) * 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7653438B2 (en) * 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8347891B2 (en) * 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US20050033137A1 (en) * 2002-10-25 2005-02-10 The Regents Of The University Of Michigan Ablation catheters and methods for their use
US7938828B2 (en) * 2003-03-28 2011-05-10 Boston Scientific Scimed, Inc. Cooled ablation catheter
US20050149132A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation based on cardiac activity
US8691877B2 (en) 2004-10-15 2014-04-08 Palo Alto Investors Methods and compositions for treating a disease condition in a subject
US7937143B2 (en) 2004-11-02 2011-05-03 Ardian, Inc. Methods and apparatus for inducing controlled renal neuromodulation
US7561923B2 (en) * 2005-05-09 2009-07-14 Cardiac Pacemakers, Inc. Method and apparatus for controlling autonomic balance using neural stimulation
US20080091193A1 (en) 2005-05-16 2008-04-17 James Kauphusman Irrigated ablation catheter having magnetic tip for magnetic field control and guidance
US9861836B2 (en) * 2005-06-16 2018-01-09 Biosense Webster, Inc. Less invasive methods for ablation of fat pads
US8660647B2 (en) 2005-07-28 2014-02-25 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US20070156200A1 (en) 2005-12-29 2007-07-05 Lilian Kornet System and method for regulating blood pressure and electrolyte balance
JP5256048B2 (ja) * 2006-02-03 2013-08-07 シネコー・エルエルシー 神経調節のための脈管内デバイス
CN105056408B (zh) 2006-06-28 2018-09-25 美敦力Af卢森堡公司 用于热诱导的肾神经调制的系统
US20080076991A1 (en) * 2006-09-21 2008-03-27 Starr Life Sciences Corp. Medical display devices for cardiac and breathing parameters derived from extra-thoracic blood flow measurements
US11395694B2 (en) 2009-05-07 2022-07-26 St. Jude Medical, Llc Irrigated ablation catheter with multiple segmented ablation electrodes
CN101888807B (zh) * 2007-11-30 2014-02-19 圣朱德医疗有限公司房颤分公司 具有用于磁场控制和引导的磁性尖端的冲洗消融导管
JP5153892B2 (ja) 2008-02-07 2013-02-27 カーディアック ペースメイカーズ, インコーポレイテッド 無線組織電気刺激
WO2009121009A2 (en) * 2008-03-27 2009-10-01 The Regents Of The University Of California Irreversible electroporation device for use in attenuating neointimal
US20100114244A1 (en) 2008-10-31 2010-05-06 Medtronic, Inc. Electrical renal autonomic blockade
US20100168739A1 (en) 2008-12-31 2010-07-01 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
WO2010148088A2 (en) * 2009-06-16 2010-12-23 Surgivision, Inc. Mri-guided devices and mri-guided interventional systems that can track and generate dynamic visualizations of the devices in near real time
CN201469401U (zh) 2009-08-21 2010-05-19 刘小青 螺旋状环肾动脉肾交感神经射频消融电极导管
US9174065B2 (en) * 2009-10-12 2015-11-03 Kona Medical, Inc. Energetic modulation of nerves
US8517962B2 (en) 2009-10-12 2013-08-27 Kona Medical, Inc. Energetic modulation of nerves
US20110092880A1 (en) 2009-10-12 2011-04-21 Michael Gertner Energetic modulation of nerves
US20110200171A1 (en) 2010-01-19 2011-08-18 Ardian, Inc. Methods and apparatus for renal neuromodulation via stereotactic radiotherapy
US8975233B2 (en) 2010-01-26 2015-03-10 Northwind Medical, Inc. Methods for renal denervation
US8870863B2 (en) * 2010-04-26 2014-10-28 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
RU2477158C2 (ru) 2010-09-02 2013-03-10 Федеральное государственное учреждение "Новосибирский научно-исследовательский институт патологии кровообращения имени академика Е.Н.Мешалкина" Министерства здравоохранения и социального развития Российской Федерации (ФГУ "ННИИПК им. акад. Е.Н.Мешалкина" Минздравсоцразвития РФ) Способ лечения фибрилляции предсердий у пациентов с артериальной гипертензией
US20120059286A1 (en) 2010-09-07 2012-03-08 Roger Hastings Self-Powered Ablation Catheter for Renal Denervation
RU2445013C1 (ru) 2010-09-07 2012-03-20 Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Федерального агентства по высокотехнологичной медицинской помощи" Способ лечения рака левой почки с тромбом, прорастающим в кровеносный сосуд
ES2751156T3 (es) 2010-10-20 2020-03-30 Medtronic Ardian Luxembourg Aparatos de catéter que tienen estructuras de malla expansibles para neuromodulación renal
TWI556849B (zh) 2010-10-21 2016-11-11 美敦力阿福盧森堡公司 用於腎臟神經協調的導管裝置
EP3100696B1 (en) 2010-10-25 2023-01-11 Medtronic Ardian Luxembourg S.à.r.l. Catheter apparatuses having multi-electrode arrays for renal neuromodulation
US20120123326A1 (en) 2010-11-12 2012-05-17 Christian Steven C Catheter systems with distal end function, such as distal deflection, using remote actuation or low input force
AU2011329669B2 (en) 2010-11-19 2016-07-28 Boston Scientific Scimed, Inc. Renal nerve detection and ablation apparatus and method
US10016233B2 (en) * 2010-12-06 2018-07-10 Biosense Webster (Israel) Ltd. Treatment of atrial fibrillation using high-frequency pacing and ablation of renal nerves
US20120150169A1 (en) 2010-12-09 2012-06-14 Medtronic, Inc. Impedance measurement to monitor organ perfusion or hemodynamic status
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US20120184952A1 (en) 2011-01-19 2012-07-19 Jenson Mark L Low-profile off-wall electrode device for renal nerve ablation
EP2667812A1 (en) 2011-01-28 2013-12-04 Medtronic Ardian Luxembourg S.à.r.l. Ablation catheter equipped with a shape memory material
CN202184797U (zh) 2011-04-06 2012-04-11 湖南依微迪医疗器械有限公司 高血压血管内治疗导管
CN102125725A (zh) 2011-04-06 2011-07-20 湖南依微迪医疗器械有限公司 高血压血管内治疗导管
CN102125460B (zh) 2011-04-15 2012-11-28 深圳市惠泰医疗器械有限公司 肾动脉射频消融导管及其制备方法
CN102274074A (zh) 2011-05-03 2011-12-14 上海微创电生理医疗科技有限公司 多极开放式射频消融导管
CN102198015B (zh) 2011-05-03 2013-11-06 上海微创电生理医疗科技有限公司 可伸缩螺旋叠环式电极导管
US20120290024A1 (en) 2011-05-11 2012-11-15 St. Jude Medical, Inc. Transvenous renal nerve modulation for treatment of hypertension, cardiovascular disorders, and chronic renal diseases
US8909316B2 (en) 2011-05-18 2014-12-09 St. Jude Medical, Cardiology Division, Inc. Apparatus and method of assessing transvascular denervation
RU2638438C2 (ru) * 2011-08-26 2017-12-13 Симап Холдинг Лимитед Система и способ определения места расположения и идентификации функциональных нервов, иннервирующих стенку артерий, и катетеры для них
US9820811B2 (en) * 2011-08-26 2017-11-21 Symap Medical (Suzhou), Ltd System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same
US20190110704A1 (en) 2017-10-06 2019-04-18 Symap Medical (Suzhou), Limited System and method for mapping the functional nerves innervating the wall of arteries, 3-d mapping and catheters for same
US8702619B2 (en) * 2011-08-26 2014-04-22 Symap Holding Limited Mapping sympathetic nerve distribution for renal ablation and catheters for same
CN102551874B (zh) 2011-10-20 2015-07-22 上海微创电生理医疗科技有限公司 肾动脉射频消融导管
US9327123B2 (en) 2011-11-07 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Endovascular nerve monitoring devices and associated systems and methods
CN202365923U (zh) 2011-12-07 2012-08-08 北京天助畅运医疗技术股份有限公司 肾神经射频消融涂层电极
US8825130B2 (en) 2011-12-30 2014-09-02 St. Jude Medical, Atrial Fibrillation Division, Inc. Electrode support structure assemblies
AU2013211951B2 (en) 2012-01-26 2017-02-16 Autonomix Medical, Inc. Controlled sympathectomy and micro-ablation systems and methods
US9439598B2 (en) 2012-04-12 2016-09-13 NeuroMedic, Inc. Mapping and ablation of nerves within arteries and tissues
CN102631240A (zh) 2012-04-13 2012-08-15 上海微创电生理医疗科技有限公司 冷盐水灌注型射频消融导管
CN102688093B (zh) 2012-06-20 2014-08-27 深圳市惠泰医疗器械有限公司 肾动脉冷盐水射频消融可控电极导管
CN202637111U (zh) 2012-06-20 2013-01-02 深圳市惠泰医疗器械有限公司 肾动脉冷盐水射频消融可控电极导管
CN203138452U (zh) 2012-08-24 2013-08-21 苏州信迈医疗器械有限公司 一种能够定位或识别位于血管壁内或外膜上的神经的仪器
CN102908189B (zh) 2012-08-29 2015-04-08 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经多功能消融导管系统
CN102885649B (zh) 2012-08-29 2015-01-21 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经射频线控消融导管系统
CN202843784U (zh) 2012-08-29 2013-04-03 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经消融导管系统
CN102908188B (zh) 2012-08-29 2015-04-08 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经射频消融导管系统
CN202761434U (zh) 2012-08-29 2013-03-06 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经多功能消融导管系统
CN102885648B (zh) 2012-08-29 2015-03-18 中国人民解放军第三军医大学第一附属医院 肾脏去交感神经消融导管系统
EP2895095A2 (en) 2012-09-17 2015-07-22 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
WO2014047411A1 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
CN102940526A (zh) 2012-10-17 2013-02-27 上海安通医疗科技有限公司 一种推拉控制头电极的射频消融导管
CN202933012U (zh) 2012-10-17 2013-05-15 上海安通医疗科技有限公司 一种推拉控制头电极的射频消融导管
CN104902836B (zh) 2012-11-05 2017-08-08 毕达哥拉斯医疗有限公司 受控组织消融
CN203042429U (zh) 2012-12-31 2013-07-10 上海安通医疗科技有限公司 一种可操控式射频导管电极装置
JP6422894B2 (ja) 2013-02-08 2018-11-14 アクタス メディカル インクAcutus Medical,Inc. フレキシブルプリント回路板を備える拡張可能なカテーテルアッセンブリ
EP3054881A4 (en) 2013-10-15 2017-06-14 Autonomix Medical, Inc. Systems and methods for treating cancer and/or augmenting organ function
CN106659531A (zh) 2014-05-07 2017-05-10 毕达哥拉斯医疗有限公司 受控组织消融技术
US20160078307A1 (en) 2014-09-17 2016-03-17 Thomas D. Pawlik System for authenticating an object

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6292695B1 (en) * 1998-06-19 2001-09-18 Wilton W. Webster, Jr. Method and apparatus for transvascular treatment of tachycardia and fibrillation
WO2008061150A2 (en) * 2006-11-14 2008-05-22 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation or denervation

Also Published As

Publication number Publication date
AU2012303696B2 (en) 2014-05-29
CA2846395A1 (en) 2013-03-07
US20170296265A1 (en) 2017-10-19
EP2747691B1 (en) 2019-10-09
EP3659537B1 (en) 2023-12-06
CN103796604A (zh) 2014-05-14
JP6188159B2 (ja) 2017-08-30
JP2019195674A (ja) 2019-11-14
US10842559B2 (en) 2020-11-24
US20240024024A1 (en) 2024-01-25
IL231127A (en) 2015-01-29
US11337748B2 (en) 2022-05-24
JP2017213393A (ja) 2017-12-07
EP3659537A1 (en) 2020-06-03
US20140194866A1 (en) 2014-07-10
US20150289770A1 (en) 2015-10-15
US9723998B2 (en) 2017-08-08
US20250072961A1 (en) 2025-03-06
KR101862903B1 (ko) 2018-05-30
US20210393320A9 (en) 2021-12-23
SG2014013957A (en) 2014-03-28
ES2972941T3 (es) 2024-06-17
US10111708B2 (en) 2018-10-30
WO2013030743A1 (en) 2013-03-07
US20210085389A1 (en) 2021-03-25
EP2747691A1 (en) 2014-07-02
RU2638438C2 (ru) 2017-12-13
WO2013030738A1 (en) 2013-03-07
EP2747691A4 (en) 2015-08-19
US20150216590A1 (en) 2015-08-06
KR20140053335A (ko) 2014-05-07
US20180042670A1 (en) 2018-02-15
US9770291B2 (en) 2017-09-26
US9375154B2 (en) 2016-06-28
IL231127A0 (en) 2014-03-31
AU2012303701A1 (en) 2013-05-02
CN203089369U (zh) 2013-07-31
US20140213873A1 (en) 2014-07-31
SG11201501257UA (en) 2015-04-29
US20190076191A1 (en) 2019-03-14
EP3659537C0 (en) 2023-12-06
RU2015110113A (ru) 2016-12-27
US9022948B2 (en) 2015-05-05
CA2846395C (en) 2018-05-22
CN103796604B (zh) 2017-03-01
US20160374568A1 (en) 2016-12-29
AU2012303696A1 (en) 2013-05-02
ZA201402085B (en) 2015-08-26
US9014821B2 (en) 2015-04-21
JP2014525814A (ja) 2014-10-02
ES2765011T3 (es) 2020-06-05
JP6905759B2 (ja) 2021-07-21

Similar Documents

Publication Publication Date Title
US20250072961A1 (en) System and method for locating and identifying the functional nerves innervating the wall of arteries and catheters for same
US11576721B2 (en) System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same
AU2016362114B2 (en) System and method for mapping functional nerves innervating wall of arteries,3-D mapping and catheters for same
US20210145342A1 (en) System and method for mapping the functional nerves innervating the wall of arteries, 3-d mapping and catheters for same
US9743845B2 (en) Mapping sympathetic nerve distribution for renal ablation and catheters for same
IL282001B2 (en) A method and system for mapping a functional wall of arteries, three-dimensional mapping and catheters for this purpose
US20230210593A1 (en) System and method for mapping the functional nerves innervating the wall of arteries, 3-d mapping and catheters for same
US20260000446A1 (en) System and method for mapping the functional nerves innervating the wall of arteries, 3-d mapping and catheters for same

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: SYMAP HOLDING LIMITED

Free format text: FORMER APPLICANT(S): SYMAP MEDICAL LIMITED

FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: SYMAP MEDICAL (SUZHOU), LTD

Free format text: FORMER OWNER WAS: SYMAP HOLDING LIMITED