AU2005316739A1 - Spiro derivatives as lipoxygenase inhibitors - Google Patents

Spiro derivatives as lipoxygenase inhibitors Download PDF

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Publication number
AU2005316739A1
AU2005316739A1 AU2005316739A AU2005316739A AU2005316739A1 AU 2005316739 A1 AU2005316739 A1 AU 2005316739A1 AU 2005316739 A AU2005316739 A AU 2005316739A AU 2005316739 A AU2005316739 A AU 2005316739A AU 2005316739 A1 AU2005316739 A1 AU 2005316739A1
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AU
Australia
Prior art keywords
cyclobutan
chromene
dihydrospiro
dimethyl
cyclobutane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2005316739A
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English (en)
Inventor
Jian Chen
Daniel T. W. Chu
Qiang Cong
Donald R. James
Xianfeng Li
Jiangao Song
Bing Wang
Wei Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galileo Pharmaceuticals Inc
Original Assignee
Galileo Pharmaceuticals Inc
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Filing date
Publication date
Application filed by Galileo Pharmaceuticals Inc filed Critical Galileo Pharmaceuticals Inc
Publication of AU2005316739A1 publication Critical patent/AU2005316739A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Organic Chemistry (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
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AU2005316739A 2004-12-13 2005-12-09 Spiro derivatives as lipoxygenase inhibitors Abandoned AU2005316739A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US63558104P 2004-12-13 2004-12-13
US60/635,581 2004-12-13
US65671005P 2005-02-25 2005-02-25
US65670905P 2005-02-25 2005-02-25
US60/656,709 2005-02-25
US60/656,710 2005-02-25
US67538605P 2005-04-27 2005-04-27
US60/675,386 2005-04-27
US70258005P 2005-07-26 2005-07-26
US60/702,580 2005-07-26
PCT/US2005/044768 WO2006065686A2 (en) 2004-12-13 2005-12-09 Spiro derivatives as lipoxygenase inhibitors

Publications (1)

Publication Number Publication Date
AU2005316739A1 true AU2005316739A1 (en) 2006-06-22

Family

ID=36370831

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005316739A Abandoned AU2005316739A1 (en) 2004-12-13 2005-12-09 Spiro derivatives as lipoxygenase inhibitors

Country Status (8)

Country Link
US (1) US7576094B2 (https=)
EP (1) EP1836183A2 (https=)
JP (1) JP2008523145A (https=)
AU (1) AU2005316739A1 (https=)
BR (1) BRPI0519013A2 (https=)
CA (1) CA2589363A1 (https=)
MX (1) MX2007007103A (https=)
WO (1) WO2006065686A2 (https=)

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MX2010011762A (es) * 2008-06-17 2011-02-03 Glenmark Pharmaceuticals Sa Derivados de cromano como moduladores del trpv3.
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CA2924141C (en) 2013-08-22 2022-06-07 The General Hospital Corporation 5-amino 4-cyano substituted oxazole and thiazole derivatives as inhibitors of human 12/15-lipoxygenase
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WO2016168510A1 (en) 2015-04-17 2016-10-20 Peloton Therapeutics, Inc. Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof
US9796697B2 (en) 2015-06-12 2017-10-24 Peloton Therapeutics, Inc. Tricyclic inhibitors of HIF-2-alpha and uses thereof
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WO2006065686A3 (en) 2006-08-24
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