AU2005222902B2 - iRNA agents targeting VEGF - Google Patents

iRNA agents targeting VEGF Download PDF

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Publication number
AU2005222902B2
AU2005222902B2 AU2005222902A AU2005222902A AU2005222902B2 AU 2005222902 B2 AU2005222902 B2 AU 2005222902B2 AU 2005222902 A AU2005222902 A AU 2005222902A AU 2005222902 A AU2005222902 A AU 2005222902A AU 2005222902 B2 AU2005222902 B2 AU 2005222902B2
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AU
Australia
Prior art keywords
irna agent
seq
nucleotide
irna
vegf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005222902A
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English (en)
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AU2005222902A1 (en
Inventor
Antonin De Fougerolles
Maria Frank-Kamenetsky
Phillipp Hadwiger
Muthiah Manoharan
Kallanthottahil G. Rajeev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alnylam Pharmaceuticals Inc
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Alnylam Pharmaceuticals Inc
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Publication date
Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of AU2005222902A1 publication Critical patent/AU2005222902A1/en
Application granted granted Critical
Publication of AU2005222902B2 publication Critical patent/AU2005222902B2/en
Priority to AU2010212443A priority Critical patent/AU2010212443B8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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AU2005222902A 2004-03-12 2005-03-11 iRNA agents targeting VEGF Ceased AU2005222902B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010212443A AU2010212443B8 (en) 2004-03-12 2010-08-19 iRNA agents targeting VEGF

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US55262004P 2004-03-12 2004-03-12
US60/552,620 2004-03-12
US55982404P 2004-04-05 2004-04-05
US60/559,824 2004-04-05
US64719105P 2005-01-25 2005-01-25
US60/647,191 2005-01-25
PCT/US2005/008182 WO2005089224A2 (en) 2004-03-12 2005-03-11 iRNA AGENTS TARGETING VEGF

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2010212443A Division AU2010212443B8 (en) 2004-03-12 2010-08-19 iRNA agents targeting VEGF

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AU2005222902A1 AU2005222902A1 (en) 2005-09-29
AU2005222902B2 true AU2005222902B2 (en) 2010-06-10

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AU2005222902A Ceased AU2005222902B2 (en) 2004-03-12 2005-03-11 iRNA agents targeting VEGF
AU2010212443A Ceased AU2010212443B8 (en) 2004-03-12 2010-08-19 iRNA agents targeting VEGF

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AU2010212443A Ceased AU2010212443B8 (en) 2004-03-12 2010-08-19 iRNA agents targeting VEGF

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US (5) US7947659B2 (enExample)
EP (4) EP1735009A4 (enExample)
JP (4) JP4937899B2 (enExample)
AU (2) AU2005222902B2 (enExample)
CA (1) CA2559161C (enExample)
ES (1) ES2423060T3 (enExample)
WO (1) WO2005089224A2 (enExample)

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US7148342B2 (en) 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
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US9839649B2 (en) 2002-11-14 2017-12-12 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
US10011836B2 (en) 2002-11-14 2018-07-03 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
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