AU2003289338A1 - Novel nitrile hydratase - Google Patents
Novel nitrile hydratase Download PDFInfo
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- AU2003289338A1 AU2003289338A1 AU2003289338A AU2003289338A AU2003289338A1 AU 2003289338 A1 AU2003289338 A1 AU 2003289338A1 AU 2003289338 A AU2003289338 A AU 2003289338A AU 2003289338 A AU2003289338 A AU 2003289338A AU 2003289338 A1 AU2003289338 A1 AU 2003289338A1
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- amino acid
- sequence
- subunit
- nitrile hydratase
- seq
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01084—Nitrile hydratase (4.2.1.84)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
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|---|---|---|---|
| AU2010202683A AU2010202683B2 (en) | 2002-12-19 | 2010-06-28 | Novel nitrile hydratase |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002368360A JP2004194588A (ja) | 2002-12-19 | 2002-12-19 | 新規なニトリルヒドラターゼ |
| JP2002-368360 | 2002-12-19 | ||
| JP2003-379280 | 2003-11-10 | ||
| JP2003379280 | 2003-11-10 | ||
| PCT/JP2003/016014 WO2004056990A1 (ja) | 2002-12-19 | 2003-12-15 | 新規なニトリルヒドラターゼ |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| AU2010202683A Division AU2010202683B2 (en) | 2002-12-19 | 2010-06-28 | Novel nitrile hydratase |
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| AU2003289338A1 true AU2003289338A1 (en) | 2004-07-14 |
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| AU2003289338A Abandoned AU2003289338A1 (en) | 2002-12-19 | 2003-12-15 | Novel nitrile hydratase |
| AU2010202683A Expired AU2010202683B2 (en) | 2002-12-19 | 2010-06-28 | Novel nitrile hydratase |
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| Application Number | Title | Priority Date | Filing Date |
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| AU2010202683A Expired AU2010202683B2 (en) | 2002-12-19 | 2010-06-28 | Novel nitrile hydratase |
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| US (1) | US7595184B2 (enExample) |
| EP (1) | EP1586637B1 (enExample) |
| JP (1) | JP2004194588A (enExample) |
| KR (5) | KR100819228B1 (enExample) |
| CN (4) | CN101892211A (enExample) |
| AU (2) | AU2003289338A1 (enExample) |
| WO (1) | WO2004056990A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005248259B2 (en) * | 2004-05-26 | 2010-07-08 | Mitsubishi Chemical Corporation | Improved nitrile hydratase |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1842907A1 (en) | 2006-04-07 | 2007-10-10 | B.R.A.I.N. Ag | A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity |
| JP5069032B2 (ja) * | 2007-04-04 | 2012-11-07 | ダイヤニトリックス株式会社 | 改良型ニトリルヒドラターゼ |
| JP5551081B2 (ja) * | 2008-11-14 | 2014-07-16 | 三井化学株式会社 | ニトリルヒドラターゼ変異体 |
| JP5532618B2 (ja) * | 2009-01-30 | 2014-06-25 | 三菱レイヨン株式会社 | 改良型ニトリルヒドラターゼ及びその製造方法 |
| CN102575273B (zh) * | 2009-04-30 | 2015-01-28 | 三井化学株式会社 | 制造3-巯基丙酸或其盐的方法 |
| US9388403B2 (en) | 2011-05-31 | 2016-07-12 | Mitsubishi Rayon Co., Ltd. | Nitrile hydratase |
| KR101586132B1 (ko) | 2011-06-07 | 2016-01-19 | 미쯔비시 레이온 가부시끼가이샤 | 개량형 니트릴 히드라타제 |
| CN102517271B (zh) * | 2011-12-13 | 2013-04-03 | 清华大学 | 一种突变腈水合酶 |
| JP6489013B2 (ja) | 2014-06-06 | 2019-03-27 | 三菱ケミカル株式会社 | 改良型ニトリルヒドラターゼ |
| CN104725476B (zh) * | 2015-03-31 | 2018-10-16 | 清华大学 | 一种钩状结构寡肽及其应用 |
| EP3564368B1 (en) * | 2016-12-28 | 2025-03-26 | Mitsui Chemicals, Inc. | Mutant nitrile hydratase, nucleic acid coding said mutant nitrile hydratase, expression vector and transformant including said nucleic acid, production method for said mutant nitrile hydratase, and production method for amide compound |
| KR20190049109A (ko) | 2017-11-01 | 2019-05-09 | (주)대화정공 | 풀리 제조방법 |
| KR102068615B1 (ko) | 2019-04-08 | 2020-01-21 | (주)대화정공 | 자동차 댐퍼풀리 제조방법 |
| KR102146408B1 (ko) | 2019-04-08 | 2020-08-21 | (주)대화정공 | 단류선 개선을 위해 압연롤러를 이용한 자동차 댐퍼풀리 제조방법 |
| CN111690675B (zh) * | 2019-08-01 | 2022-07-19 | 安徽瑞邦生物科技有限公司 | 一种表达腈水合酶突变体的重组菌及其制备方法和应用 |
| CN112322606B (zh) * | 2020-11-20 | 2022-05-10 | 江南大学 | 一种腈水合酶突变体及其应用 |
| CN112522245A (zh) * | 2020-12-09 | 2021-03-19 | 江南大学 | 一种腈水合酶氨基酸基序的改造及其应用 |
| CN113151234B (zh) * | 2021-04-13 | 2022-08-12 | 浙江工业大学 | 腈水合酶赖氨酸突变体hba-k2h2r、编码基因及应用 |
| CN113444714B (zh) * | 2021-07-29 | 2022-06-21 | 浙江大学杭州国际科创中心 | 一种β亚基突变的腈水合酶突变体及其应用 |
| CN114317507B (zh) * | 2021-11-30 | 2024-07-02 | 清华大学 | 腈水合酶突变体及其应用 |
| KR20250011936A (ko) * | 2022-06-30 | 2025-01-22 | 미쓰이 가가쿠 가부시키가이샤 | 변이형 나이트릴 하이드라타제, 그 변이형 나이트릴 하이드라타제를 코딩하는 핵산, 그 핵산을 포함하는 벡터 및 형질 전환체, 그 변이형 나이트릴 하이드라타제의 제조 방법, 및 아마이드 화합물의 제조 방법 |
| CN115772514B (zh) * | 2022-11-03 | 2025-03-04 | 无锡新晨宇生物工程有限公司 | 一种腈水合酶底物通道氨基酸基序的改造用于肉桂酰胺的制备 |
| EP4600368A1 (en) * | 2024-02-09 | 2025-08-13 | Adisseo France S.A.S. | A method for enzymatic production of an amide compound |
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| DD274631A5 (de) | 1987-09-18 | 1989-12-27 | Kk | Verfahren zur biologischen herstellung von amiden |
| AU627648B2 (en) | 1990-02-28 | 1992-08-27 | Teruhiko Beppu | Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant |
| JPH0856684A (ja) | 1994-08-16 | 1996-03-05 | Mitsui Toatsu Chem Inc | 微生物によるアミド化合物の製造法 |
| JP3380133B2 (ja) * | 1996-02-14 | 2003-02-24 | 三井化学株式会社 | 新規なニトリルヒドラターゼ |
| CN1260363C (zh) | 1996-02-14 | 2006-06-21 | 三井化学株式会社 | 由腈化合物生产酰胺的方法 |
| JP3408737B2 (ja) | 1998-03-16 | 2003-05-19 | 三井化学株式会社 | ニトリルヒドラターゼの活性化に関与するタンパク質及びそれをコードする遺伝子 |
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2003
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- 2003-12-15 AU AU2003289338A patent/AU2003289338A1/en not_active Abandoned
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- 2003-12-15 WO PCT/JP2003/016014 patent/WO2004056990A1/ja not_active Ceased
- 2003-12-15 KR KR1020057011335A patent/KR100825147B1/ko not_active Expired - Lifetime
- 2003-12-15 CN CNA2003801069930A patent/CN1729288A/zh active Pending
- 2003-12-15 CN CN2012105742117A patent/CN103215242A/zh active Pending
- 2003-12-15 KR KR1020077015994A patent/KR100794001B1/ko not_active Expired - Lifetime
- 2003-12-15 US US10/539,560 patent/US7595184B2/en not_active Expired - Lifetime
- 2003-12-15 EP EP03780752.6A patent/EP1586637B1/en not_active Expired - Lifetime
- 2003-12-15 KR KR1020067026866A patent/KR100785548B1/ko not_active Expired - Lifetime
- 2003-12-15 CN CN2012105742761A patent/CN103103175A/zh active Pending
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005248259B2 (en) * | 2004-05-26 | 2010-07-08 | Mitsubishi Chemical Corporation | Improved nitrile hydratase |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070110146A (ko) | 2007-11-15 |
| KR20070011620A (ko) | 2007-01-24 |
| CN103103175A (zh) | 2013-05-15 |
| KR20070007393A (ko) | 2007-01-15 |
| CN101892211A (zh) | 2010-11-24 |
| EP1586637A1 (en) | 2005-10-19 |
| CN1729288A (zh) | 2006-02-01 |
| KR100785549B1 (ko) | 2007-12-12 |
| KR20070087054A (ko) | 2007-08-27 |
| KR100819228B1 (ko) | 2008-04-03 |
| JP2004194588A (ja) | 2004-07-15 |
| KR20050089972A (ko) | 2005-09-09 |
| EP1586637A4 (en) | 2008-03-19 |
| US20070009985A1 (en) | 2007-01-11 |
| KR100785548B1 (ko) | 2007-12-12 |
| CN103215242A (zh) | 2013-07-24 |
| WO2004056990A1 (ja) | 2004-07-08 |
| AU2010202683A1 (en) | 2010-07-15 |
| EP1586637B1 (en) | 2014-02-26 |
| US7595184B2 (en) | 2009-09-29 |
| KR100794001B1 (ko) | 2008-01-10 |
| KR100825147B1 (ko) | 2008-04-24 |
| AU2010202683B2 (en) | 2012-01-19 |
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