AU2003230245A1 - (S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor - Google Patents

(S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor Download PDF

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Publication number
AU2003230245A1
AU2003230245A1 AU2003230245A AU2003230245A AU2003230245A1 AU 2003230245 A1 AU2003230245 A1 AU 2003230245A1 AU 2003230245 A AU2003230245 A AU 2003230245A AU 2003230245 A AU2003230245 A AU 2003230245A AU 2003230245 A1 AU2003230245 A1 AU 2003230245A1
Authority
AU
Australia
Prior art keywords
compound
addition salt
amino
acid addition
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003230245A
Other languages
English (en)
Inventor
Yoshimi Hirokawa
Yoko Kan
Shiro Kato
Kazuo Morikage
Yukiko Morikage
Hiroshi Yamazaki
Naoyuki Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Publication of AU2003230245A1 publication Critical patent/AU2003230245A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2003230245A 2002-05-16 2003-05-15 (S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor Abandoned AU2003230245A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002-141262 2002-05-16
JP2002141262 2002-05-16
PCT/JP2003/006051 WO2003097638A1 (en) 2002-05-16 2003-05-15 (s)-4-amino-5-chloro-2-methoxy-n-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor

Publications (1)

Publication Number Publication Date
AU2003230245A1 true AU2003230245A1 (en) 2003-12-02

Family

ID=29267809

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003230245A Abandoned AU2003230245A1 (en) 2002-05-16 2003-05-15 (S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor

Country Status (26)

Country Link
US (1) US6696468B2 (https=)
EP (1) EP1362857B1 (https=)
JP (1) JP3643107B2 (https=)
KR (1) KR20040107520A (https=)
CN (1) CN1653063A (https=)
AR (1) AR040021A1 (https=)
AT (1) ATE273304T1 (https=)
AU (1) AU2003230245A1 (https=)
BR (1) BR0309933A (https=)
CA (1) CA2483368A1 (https=)
CZ (1) CZ20041084A3 (https=)
DE (1) DE60300021T2 (https=)
DK (1) DK1362857T3 (https=)
ES (1) ES2227500T3 (https=)
HU (1) HUP0501016A2 (https=)
IL (1) IL165012A0 (https=)
MX (1) MXPA04011332A (https=)
NO (1) NO20045469L (https=)
PL (1) PL372724A1 (https=)
PT (1) PT1362857E (https=)
RU (1) RU2004136853A (https=)
SK (1) SK50192004A3 (https=)
TR (1) TR200403020T2 (https=)
TW (1) TW200400186A (https=)
WO (1) WO2003097638A1 (https=)
ZA (1) ZA200409053B (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US7399862B2 (en) * 2004-11-05 2008-07-15 Theravance, Inc. 5-HT4 receptor agonist compounds
WO2006052889A2 (en) * 2004-11-05 2006-05-18 Theravance, Inc. Quinolinone-carboxamide compounds
CA2588037A1 (en) * 2004-12-22 2006-06-29 Theravance, Inc. Indazole-carboxamide compounds
CN101163701A (zh) * 2005-03-02 2008-04-16 施万制药 作为5-ht4受体激动剂的喹啉酮化合物
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
MY147756A (en) 2005-05-25 2013-01-15 Theravance Inc Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
TW200722419A (en) * 2005-05-27 2007-06-16 Astrazeneca Ab Chemical compounds
US20080200505A1 (en) * 2005-05-27 2008-08-21 Astrazeneca Ab Piperidines for the Treatment of Chemokine Mediated Diseases
WO2007011293A1 (en) 2005-07-21 2007-01-25 Astrazeneca Ab Novel piperidine derivatives
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
WO2011092290A1 (en) 2010-02-01 2011-08-04 Novartis Ag Pyrazolo[5,1b]oxazole derivatives as crf-1 receptor antagonists
AR080056A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de ciclohexil-amida como antagonistas de los receptores de crf
EP2531490B1 (en) 2010-02-02 2014-10-15 Novartis AG Cyclohexyl amide derivatives as crf receptor antagonists
AR086554A1 (es) 2011-05-27 2014-01-08 Novartis Ag Derivados de la piperidina 3-espirociclica como agonistas de receptores de la ghrelina
JP2015525202A (ja) 2012-05-03 2015-09-03 ノバルティス アーゲー グレリン受容体アゴニストとしての２，７−ジアザ−スピロ［４，５］デカ−７−イル誘導体のｌ−リンゴ酸塩およびその結晶形態
IL297456A (en) * 2020-05-04 2022-12-01 Takeda Pharmaceuticals Co n-(piperidin-4-yl)benzamide derivatives are active in Nahor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH111472A (ja) 1996-04-30 1999-01-06 Dainippon Pharmaceut Co Ltd ベンズアミド誘導体及びそれを含有する医薬組成物
EP1076055B1 (en) * 1998-04-28 2004-11-24 Dainippon Pharmaceutical Co., Ltd. 1- (1-substituted-4-piperidinyl)methyl]-4-piperidine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
JP2000080081A (ja) 1998-06-24 2000-03-21 Dainippon Pharmaceut Co Ltd １―〔（１―置換―４―ピペリジニル）メチル〕―４―ピペリジン誘導体及びそれを含有する医薬組成物
JP2001122784A (ja) 1999-10-27 2001-05-08 Dainippon Pharmaceut Co Ltd １−［（１−置換−４−ピペリジニル）メチル］−４−ピペリジン誘導体からなる医薬

Also Published As

Publication number Publication date
PL372724A1 (en) 2005-07-25
HK1060118A1 (en) 2004-07-30
HUP0501016A2 (en) 2006-02-28
ZA200409053B (en) 2005-07-12
KR20040107520A (ko) 2004-12-20
US20030216433A1 (en) 2003-11-20
DE60300021D1 (de) 2004-09-16
TR200403020T2 (tr) 2005-05-23
EP1362857A1 (en) 2003-11-19
US6696468B2 (en) 2004-02-24
BR0309933A (pt) 2005-02-09
AR040021A1 (es) 2005-03-09
DK1362857T3 (da) 2004-12-20
SK50192004A3 (sk) 2005-04-01
ES2227500T3 (es) 2005-04-01
IL165012A0 (en) 2005-12-18
EP1362857B1 (en) 2004-08-11
MXPA04011332A (es) 2005-02-14
ATE273304T1 (de) 2004-08-15
CZ20041084A3 (cs) 2005-02-16
JP3643107B2 (ja) 2005-04-27
WO2003097638A1 (en) 2003-11-27
CN1653063A (zh) 2005-08-10
CA2483368A1 (en) 2003-11-27
JP2004043453A (ja) 2004-02-12
DE60300021T2 (de) 2005-09-08
TW200400186A (en) 2004-01-01
RU2004136853A (ru) 2005-06-27
NO20045469L (no) 2005-02-16
PT1362857E (pt) 2004-11-30

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