AU2003226388B2 - Methods and compositions for treating ectoparasite infestation - Google Patents
Methods and compositions for treating ectoparasite infestation Download PDFInfo
- Publication number
- AU2003226388B2 AU2003226388B2 AU2003226388A AU2003226388A AU2003226388B2 AU 2003226388 B2 AU2003226388 B2 AU 2003226388B2 AU 2003226388 A AU2003226388 A AU 2003226388A AU 2003226388 A AU2003226388 A AU 2003226388A AU 2003226388 B2 AU2003226388 B2 AU 2003226388B2
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- Australia
- Prior art keywords
- fatty acid
- composition
- ectoparasites
- acid ester
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- VJFUPGQZSXIULQ-XIGJTORUSA-N pyrethrin II Chemical compound CC1(C)[C@H](/C=C(\C)C(=O)OC)[C@H]1C(=O)O[C@@H]1C(C)=C(C\C=C/C=C)C(=O)C1 VJFUPGQZSXIULQ-XIGJTORUSA-N 0.000 description 1
- 239000002728 pyrethroid Substances 0.000 description 1
- 229960002290 pyridostigmine Drugs 0.000 description 1
- NHDHVHZZCFYRSB-UHFFFAOYSA-N pyriproxyfen Chemical compound C=1C=CC=NC=1OC(C)COC(C=C1)=CC=C1OC1=CC=CC=C1 NHDHVHZZCFYRSB-UHFFFAOYSA-N 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 239000000018 receptor agonist Substances 0.000 description 1
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- 208000005687 scabies Diseases 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000015424 sodium Nutrition 0.000 description 1
- HVFAVOFILADWEZ-UHFFFAOYSA-M sodium;2-[2-(dodecanoylamino)ethyl-(2-hydroxyethyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCC(=O)NCCN(CCO)CC([O-])=O HVFAVOFILADWEZ-UHFFFAOYSA-M 0.000 description 1
- HWCHICTXVOMIIF-UHFFFAOYSA-M sodium;3-(dodecylamino)propanoate Chemical compound [Na+].CCCCCCCCCCCCNCCC([O-])=O HWCHICTXVOMIIF-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
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- 239000010959 steel Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229960002607 sulconazole Drugs 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/32—Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/002—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing a foodstuff as carrier or diluent, i.e. baits
- A01N25/006—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing a foodstuff as carrier or diluent, i.e. baits insecticidal
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Insects & Arthropods (AREA)
- Emergency Medicine (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008203312A AU2008203312B2 (en) | 2002-04-29 | 2008-07-24 | Methods and compositions for treating ectoparasite infestation |
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|---|---|---|---|
| US10/136,075 | 2002-04-29 | ||
| US10/136,075 US6663876B2 (en) | 2002-04-29 | 2002-04-29 | Methods and compositions for treating ectoparasite infestation |
| PCT/US2003/011527 WO2003092583A2 (en) | 2002-04-29 | 2003-04-14 | Methods and compositions for treating ectoparasite infestation |
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|---|---|---|---|
| AU2008203312A Division AU2008203312B2 (en) | 2002-04-29 | 2008-07-24 | Methods and compositions for treating ectoparasite infestation |
Publications (2)
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| AU2003226388A1 AU2003226388A1 (en) | 2003-11-17 |
| AU2003226388B2 true AU2003226388B2 (en) | 2008-04-24 |
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| AU2008203312A Expired AU2008203312B2 (en) | 2002-04-29 | 2008-07-24 | Methods and compositions for treating ectoparasite infestation |
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| AU2008203312A Expired AU2008203312B2 (en) | 2002-04-29 | 2008-07-24 | Methods and compositions for treating ectoparasite infestation |
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| EP (2) | EP1499184B1 (enExample) |
| JP (3) | JP2005529896A (enExample) |
| CN (2) | CN101912381B (enExample) |
| AU (2) | AU2003226388B2 (enExample) |
| BR (1) | BRPI0309696B8 (enExample) |
| CA (2) | CA2484183C (enExample) |
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| PT (2) | PT2286663T (enExample) |
| WO (1) | WO2003092583A2 (enExample) |
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| US6683065B1 (en) * | 1999-08-19 | 2004-01-27 | Host Pharmaceuticals Llc | Method of treating body insect infestation |
| US6889632B2 (en) * | 2002-09-12 | 2005-05-10 | The Hartz Mountain Corporation | High concentration dinotefuran formulations containing methoprene |
| US7354595B2 (en) * | 2002-09-12 | 2008-04-08 | Summit Vetpharm, Llc | High concentration dinotefuran formulations |
| US7132448B2 (en) | 2002-09-12 | 2006-11-07 | The Hartz Mountain Corporation | High concentration topical insecticide containing insect growth regulator |
| US7368435B2 (en) * | 2002-09-12 | 2008-05-06 | Summit Vetpharm, Llc | Topical endoparasiticide and ectoparasiticide formulations |
| US7345092B2 (en) * | 2002-09-12 | 2008-03-18 | Summit Vetpharm, Llc | High concentration topical insecticides containing pyrethroids |
| US20050245582A1 (en) * | 2002-09-12 | 2005-11-03 | The Hartz Mountain Corporation | High concentration topical insecticides containing pyrethroids |
| GB0312195D0 (en) * | 2003-05-28 | 2003-07-02 | Syngenta Ltd | Formulation |
| US7812163B2 (en) * | 2003-07-16 | 2010-10-12 | Hatchtech Pty Ltd. | Methods and compositions for controlling ectoparasites |
| AU2003903686A0 (en) | 2003-07-16 | 2003-07-31 | Hatchtech Pty Ltd | Methods and compositions for controlling ectoparasites |
| EP1651036A1 (en) * | 2003-08-08 | 2006-05-03 | The Hartz Mountain Corporation | High concentration topical insecticides containing pyrethroids |
| HUP0400960A2 (hu) * | 2004-05-11 | 2005-12-28 | BÁBOLNA Környezetbiológiai Központ Kft. | Kifejlett és lárvaállapotú fejtetű irtására szolgáló készítmény és eljárás tetű irtására |
| US20060046988A1 (en) * | 2004-08-30 | 2006-03-02 | Albert Boeckh | Methoprene formulations for the control of tick infestations |
| DE202006004172U1 (de) * | 2006-03-13 | 2006-05-11 | G. Pohl-Boskamp Gmbh & Co. Kg | Mittel zur Bekämpfung von Ectoparasiten und deren Eiern |
| FR2907013B1 (fr) | 2006-10-12 | 2012-09-21 | Galderma Sa | Produits de soin cutane a double compartiment comprenant de l'ivermectine, et leurs utilisations |
| CA2666365C (en) * | 2006-10-12 | 2016-08-09 | Topaz Pharmaceuticals Llc | Topical avermectin formulations and methods for elimination and prophylaxis of susceptible and treatment-resistant strains of head lice |
| US8293286B2 (en) * | 2006-10-16 | 2012-10-23 | Sergeant's Pet Care Products, Inc. | Natural compositions for killing parasites on a companion animal |
| WO2009038599A1 (en) * | 2007-03-22 | 2009-03-26 | Tyratech, Inc. | Synergistic pest-control compositions |
| GB0814713D0 (en) * | 2008-08-12 | 2008-09-17 | Thornton & Ross Ltd | A method and composition for the control of ectoparasites |
| IT1393056B1 (it) * | 2008-09-22 | 2012-04-11 | Bio Lo Ga Srl | Uso di vitamina e o suoi derivati per il controllo di artropodi |
| EP2326200B8 (en) | 2008-09-23 | 2016-02-17 | Larada Sciences Inc. | Airflow applicators and related treatment methods |
| FR2940909B1 (fr) * | 2009-01-12 | 2011-02-11 | Fabre Pierre Dermo Cosmetique | Composition pharmaceutique comprenant du malathion et un silicone cyclique volatil |
| GB2470208B (en) * | 2009-05-14 | 2014-01-29 | Thornton & Ross Ltd | A method and composition for the control of ectoparasites |
| DE102009034704A1 (de) * | 2009-07-24 | 2011-01-27 | G. Pohl-Boskamp Gmbh & Co. Kg | Mittel zur Bekämpfung von Ectoparasiten |
| FR2949182B1 (fr) | 2009-08-24 | 2011-11-11 | Horizzon Innovations Technologies | Utilisation d'une microemulsion pour lutter contre les poux |
| WO2012150891A1 (en) * | 2011-05-02 | 2012-11-08 | Lipidor Ab | Composition for administration of a pharmacologically or cosmetically active agent onto a surface of a living organism |
| EP2750680B1 (en) * | 2011-08-29 | 2018-12-26 | Orna Levin | Composition for treating lice infestation |
| CA3186350A1 (en) * | 2013-02-27 | 2014-09-04 | Argenta Innovation Limited | Transdermal formulations |
| ES2967618T3 (es) | 2013-12-17 | 2024-05-03 | Hatchtech Pty Ltd | Composición pediculicida |
| GB2527026A (en) * | 2014-04-22 | 2015-12-16 | Bob Martin Uk Ltd | Veterinary composition |
| NZ728657A (en) | 2014-07-30 | 2018-06-29 | Icb Pharma Spolka Jawna | Liquid spreading composition with ectoparasiticidal activity, a method and use thereof for combating ectoparasites in human and veterinary medicine, as well as in agricultural, horticultural and/or garden environments |
| CN106999460B (zh) * | 2014-08-12 | 2021-07-09 | 信息化学和应用神经研究所 | 用于抑制海虱附着于鱼上的棕榈油酸 |
| WO2016063963A1 (ja) * | 2014-10-22 | 2016-04-28 | アース製薬株式会社 | 吸血性害虫卵の孵化阻害剤、吸血性害虫の殺虫組成物および吸血性害虫の殺虫方法 |
| US10334853B2 (en) * | 2016-03-29 | 2019-07-02 | Larada Sciences | Compositions and methods for treating ectoparasite infestation |
| US10362849B2 (en) * | 2016-06-09 | 2019-07-30 | Wipe & Remove Nits, LLC | Lice and nit removal tool and method |
| EP3424321A1 (en) | 2017-07-06 | 2019-01-09 | Ferrer Internacional, S.A. | Compounds for treating ectoparasite infestation |
| JP6898170B2 (ja) * | 2017-08-07 | 2021-07-07 | アース製薬株式会社 | 吸血性害虫の行動停止方法 |
| FR3070865A1 (fr) | 2017-09-14 | 2019-03-15 | Concept | Solution huileuse d'alcool benzylique et utilisation dans la prevention et le traitement des parasitoses |
| JP2019081752A (ja) * | 2017-10-30 | 2019-05-30 | アース製薬株式会社 | 吸血性害虫の定着阻害方法及び吸血性害虫の定着阻害剤 |
| US10328112B2 (en) | 2017-11-29 | 2019-06-25 | Michael S. Hatten | Abrasive pediculicide compositions comprising materials, kits, and methods of use |
| FR3075040A1 (fr) * | 2017-12-15 | 2019-06-21 | Laboratoires Arkopharma | Composition antiparasitaire a usage externe |
| WO2019115980A1 (fr) | 2017-12-15 | 2019-06-20 | Laboratoires Arkopharma | Composition antiparasitaire à usage externe |
| JP7140364B2 (ja) * | 2018-04-19 | 2022-09-21 | 株式会社大阪製薬 | シラミの卵駆除剤 |
| FR3085821B1 (fr) | 2018-09-19 | 2021-09-10 | Invictus | Suspension huileuse de particules submicroniques minerales pour lutter contre les poux |
| AU2020205488B2 (en) * | 2019-01-08 | 2023-03-16 | Oro Agri Inc. | A liquid anti-pathogenic agricultural composition |
| JP2021050170A (ja) * | 2019-09-26 | 2021-04-01 | 株式会社大阪製薬 | シラミ駆除剤 |
| FR3103105B1 (fr) | 2019-11-15 | 2021-11-26 | Dermowave | composition sous forme d’une solution huileuse rinçable pour lutter contre les poux |
| EP3861857A1 (en) | 2020-02-07 | 2021-08-11 | Novaliq GmbH | Antiparasitic compositions |
| CN113749092B (zh) * | 2020-06-03 | 2024-10-11 | 迈克斯(如东)化工有限公司 | 不饱和脂肪酸酯化物应用、农化组合物和低眼刺农药制剂及其应用 |
| US12342828B2 (en) | 2020-09-14 | 2025-07-01 | Insight Pharmaceuticals Corporation | Repellant formulation and method |
| US12446547B2 (en) | 2021-01-08 | 2025-10-21 | Alyssa Lynn Fox | System and method for eradicating ectoparasites |
| JP2022147060A (ja) * | 2021-03-23 | 2022-10-06 | 株式会社大阪製薬 | シラミ駆除剤 |
| JP2022167308A (ja) * | 2021-04-23 | 2022-11-04 | 株式会社大阪製薬 | シラミの成虫及び卵の駆除剤 |
| US11654128B2 (en) | 2021-05-13 | 2023-05-23 | Nuvo Pharmaceuticals (Ireland) Designated Activity Company | Methods and compositions for treating ectoparasite infestations |
| JP2024526193A (ja) * | 2021-06-25 | 2024-07-17 | イン ザ ボウル アニマル ヘルス，インコーポレーテッド | 経口のネコ科動物の飼料およびネコ科動物におけるノミの侵入を制御する方法 |
| GB2615593B8 (en) * | 2022-02-14 | 2024-05-15 | Nitoff Ltd | Head lice treatment |
| FR3134968A1 (fr) | 2022-04-28 | 2023-11-03 | Nadine PAGNOTTA GRISLAIN | Composition huileuse anti-poux à base d’alcanes liquides et ses utilisations |
| CN117088935A (zh) * | 2022-05-20 | 2023-11-21 | 上海维洱生物医药科技有限公司 | 一种雷公藤甲素木蜡酸酯及其脂质体与制备方法 |
| FR3158038A1 (fr) | 2024-01-09 | 2025-07-11 | Eric Guez | Composition antiparasitaire à usage externe à base d’acides et alcools gras |
| DE102024112133A1 (de) * | 2024-04-30 | 2025-10-30 | G. Pohl-Boskamp Gmbh & Co. Kg | Verwendung von 2-Ethylhexyllaurat enthaltenden Zusammensetzungen zur Behandlung von Ektoparasiten |
| FR3162979A1 (fr) | 2024-06-06 | 2025-12-12 | Invictus | Agent lenticide et pédiculicide à base de Laureth-4 et de MIPA-Laureth sulfate |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147800A (en) * | 1977-01-17 | 1979-04-03 | Block Drug Company, Inc. | Pediculicidal toxicants |
| US6303581B2 (en) * | 1999-01-26 | 2001-10-16 | Dale L. Pearlman | Methods and kits for removing, treating, or preventing lice with driable pedicul ostatic agents |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB564729A (en) | 1940-06-26 | 1944-10-11 | Cooper Mcdougall & Robertson | Improved insecticide |
| GB776644A (en) | 1952-02-07 | 1957-06-12 | Metallgesellschaft Ag | Preparations for the care of the human hair and scalp |
| US3341465A (en) | 1965-01-14 | 1967-09-12 | Drew Chem Corp | Novel gel emulsions |
| CH630506A5 (en) | 1977-04-29 | 1982-06-30 | Ciba Geigy Ag | Composition for controlling ectoparasites |
| US4146619A (en) | 1977-05-31 | 1979-03-27 | Block Drug Company Inc. | Siloxane toxicants |
| US4297813A (en) * | 1980-01-09 | 1981-11-03 | Cornell Research Foundation, Inc. | Multiple layer insulation cover |
| CH647392A5 (en) | 1980-07-14 | 1985-01-31 | Ciba Geigy Ag | Ectoparasiticides and insecticides |
| GB2079604B (en) | 1980-07-14 | 1983-09-01 | Ciba Geigy Ag | Pesticidal composition |
| CH647131A5 (en) | 1981-06-05 | 1985-01-15 | Ciba Geigy Ag | Pesticide |
| GB2088212B (en) | 1980-11-21 | 1985-12-04 | Wellcome Found | Pest control |
| US5286749A (en) | 1980-11-21 | 1994-02-15 | Pitman-Moore Inc. | Control of sheep ectoparasites |
| AU539105B2 (en) | 1981-10-30 | 1984-09-13 | Wellcome Australia Limited | Pour-on formulation for the control of lice |
| HUT37857A (en) | 1983-03-30 | 1986-03-28 | Sandoz Ag | Insectide compositions containing cyclodextrin inclusion complex as active substance and process for preparing the active substances |
| JPS59232198A (ja) | 1983-06-15 | 1984-12-26 | 株式会社ナサ | アタマジラミなどのシラミ駆除用シヤンプ− |
| CS238753B1 (cs) | 1983-09-22 | 1985-12-16 | Josef Moravec | Insekticidní prostředek pro hubení vši dětské a ektoparazitů domácích zvířat |
| DK191386D0 (da) | 1986-04-24 | 1986-04-24 | Koege Kemisk Vaerk | Emulgatorsystem |
| US4793708A (en) | 1987-03-27 | 1988-12-27 | Litton Systems Canada Limited | Fiber optic sensing coil |
| US4797856A (en) | 1987-04-16 | 1989-01-10 | Intel Corporation | Self-limiting erase scheme for EEPROM |
| GB8710784D0 (en) | 1987-05-07 | 1987-06-10 | Euro Celtique Sa | Tropical ectoparasiticidal composition |
| GB8726271D0 (en) | 1987-11-10 | 1987-12-16 | Univ London | Protein glycosylation assay |
| AU2632088A (en) | 1987-11-30 | 1989-06-01 | University Of Queensland, The | Improvements in the inhibition of lice |
| US4927813A (en) | 1988-03-08 | 1990-05-22 | Bernstein Joel E | Method and composition for treating pediculosis capitis |
| GB8821586D0 (en) | 1988-09-15 | 1988-10-12 | Euro Celtique Sa | Method for controlling lice/their ova |
| GB8821587D0 (en) | 1988-09-15 | 1988-10-12 | Euro Celtique Sa | Method for controlling lice/their ova |
| US5496852A (en) | 1989-02-28 | 1996-03-05 | Charwell Consumer Products, Ltd. | Louse repellent |
| NZ232874A (en) | 1989-03-13 | 1992-09-25 | Scient Chemicals Pty Ltd | Ectoparasiticide in polar solvent together miscible in aqueous component |
| GB2230446A (en) | 1989-04-12 | 1990-10-24 | Cerro Continental S A | Pediculicidal compositions |
| AU6507690A (en) | 1989-10-10 | 1991-05-16 | Peter Hugh Hull | Head lice treatment |
| WO1991005561A1 (en) | 1989-10-10 | 1991-05-02 | Peter Hugh Hull | Head lice treatment |
| US5288483A (en) | 1990-04-18 | 1994-02-22 | The Procter & Gamble Company | Anti-lice treatment compositions |
| ATE155642T1 (de) | 1990-04-18 | 1997-08-15 | Procter & Gamble | Zusammensetzungen zur bekämpfung von läusen |
| AU7756191A (en) | 1990-04-18 | 1991-11-11 | Procter & Gamble Company, The | Anti-lice treatment compositions |
| IL97151A (en) | 1991-02-05 | 1991-08-16 | Zvi Mordechai Liebman | Licidal and lice-ovicidal pharmaceutical and cosmetic formulations containing d-limonene |
| WO1994016665A2 (en) | 1993-01-25 | 1994-08-04 | Seleznev, Alexandr Georgievich | Agent to combat lice infestation |
| US5612047A (en) | 1994-03-08 | 1997-03-18 | Duffy; Eric P. | Pesticidal microemulsion formulation |
| DE4417742A1 (de) | 1994-05-20 | 1995-11-23 | Bayer Ag | Nicht-systemische Bekämpfung von Parasiten |
| US5501032A (en) | 1994-05-31 | 1996-03-26 | Fleaxperts, Inc. | Extermination of pupating insects |
| IL111554A (en) | 1994-11-08 | 1999-05-09 | Univ Ramot | Methods and compositions for hair treatment |
| DE4443888A1 (de) | 1994-12-09 | 1996-06-13 | Bayer Ag | Dermal applizierbare Formulierungen von Parasitiziden |
| DK0810823T3 (da) | 1995-02-24 | 2001-07-23 | Novartis Ag | Sammensætning til bekæmpelse af parasitter |
| US5783202A (en) | 1995-03-14 | 1998-07-21 | Soltec Research Pty. Ltd. | Pediculicidal mousse composition for killing head lice |
| ATE210451T1 (de) | 1995-05-26 | 2001-12-15 | Ropapharm B V I O | Pharmazeutische zubereitungen, auf der basis von pflanzlichen etherischen ölen für die verwendung im menschlichen oder veterinären medizinischem bereich |
| GB9601128D0 (en) | 1995-08-11 | 1996-03-20 | Pfizer Ltd | Parasiticidal compounds |
| CO4750805A1 (es) | 1995-12-13 | 1999-03-31 | Sumitomo Chemical Co | Compuesto para champu |
| US6277415B1 (en) | 1996-03-29 | 2001-08-21 | Orna Levin | Pediculocidal and veterinary compositions |
| DE19613334A1 (de) | 1996-04-03 | 1997-10-09 | Bayer Ag | Mittel zur Bekämpfung parasitierender Insekten und Milben an Menschen |
| ATE245356T1 (de) | 1996-04-29 | 2003-08-15 | Syngenta Participations Ag | Pestizidzusammensetzungen |
| IE960347A1 (en) | 1996-05-15 | 1997-11-19 | Bimeda Res Dev Ltd | Control of ectoparasites |
| FR2750861B1 (fr) | 1996-07-11 | 1998-12-24 | Rhone Merieux | Procedes d'elimination des parasites, et notamment des ectoparasites de vertebres, notamment de mammiferes et compositions pour la mise en oeuvre de ce procede |
| US5902595A (en) | 1996-07-29 | 1999-05-11 | Effcon, Inc. | Pesticidal composition and method of use |
| DK0915693T3 (da) | 1996-08-02 | 2004-02-09 | Plum Kemi Produktion As | En olie-i-vand emulsion til brug på menneskers hud for at rengøre, beskytte eller forbedre hudens tilstand |
| US6200554B1 (en) | 1996-10-16 | 2001-03-13 | The Procter & Gamble Company | Conditioning shampoo compositions having improved silicone deposition |
| US6069157A (en) | 1997-11-25 | 2000-05-30 | Pfizer Inc. | Parasiticidal compounds |
| BE1010790A3 (nl) * | 1997-03-05 | 1999-01-05 | Frans Christiaan Vangertruyden | Verpakking voor pralines. |
| US5858383A (en) | 1997-08-11 | 1999-01-12 | Summers Laboratories, Inc. | Methods and compositions for topical treatment of ectoparasites |
| AU1074299A (en) | 1997-10-10 | 1999-05-03 | Dale L. Pearlman | Methods and kits for removing, treating or preventing lice |
| US6596291B2 (en) | 1997-12-05 | 2003-07-22 | Thomas A. Bell | Compositions and methods for treating surfaces infected with ectoparasitic insects |
| US5997847A (en) | 1998-01-07 | 1999-12-07 | Spiesel; Sydney Z. | Ectoparasite detection method |
| US6130253A (en) | 1998-01-27 | 2000-10-10 | Ximed Group Plc | Terpene based pesticide treatments for killing terrestrial arthropods including, amongst others, lice, lice eggs, mites and ants |
| US5977186A (en) | 1998-01-27 | 1999-11-02 | Ximed Group Plc | Terpene treatments for killing lice and lice eggs |
| DE19807630A1 (de) | 1998-02-23 | 1999-08-26 | Bayer Ag | Wasserhaltige Mittel zur Bekämpfung parasitierender Insekten und Milben an Menschen |
| US6103248A (en) | 1998-05-22 | 2000-08-15 | Burkhart; Craig G. | Topical preparation and therapy for head lice |
| US6646011B2 (en) * | 1998-06-03 | 2003-11-11 | Johnson & Johnson Consumer Companies, Inc. | Insect repellant compositions |
| PL197431B1 (pl) * | 1998-07-02 | 2008-03-31 | Lilly Co Eli | Szampon do zwalczania wszawicy u ludzi, preparat przeciw wszawicy kondycjonujący włosy, płukanka przeciw wszawicy, zastosowanie spinozyny lub jej pochodnej lub soli do wytwarzania leku do leczenia wszawicy |
| ATE235818T1 (de) | 1998-08-07 | 2003-04-15 | Pfizer Prod Inc | Neue gelformulierung enthaltendes halsband zur bekämpfung von arthropodenbefall bei tieren |
| NL1011336C2 (nl) | 1999-02-18 | 2001-06-26 | Beaphar B V | Halsband voor een kat of hond waarbij in het materiaal van de band bepaalde werkzame stoffen zijn opgenomen en werkwijze voor de vervaardiging van een dergelijke band. |
| US6262031B1 (en) | 1999-03-12 | 2001-07-17 | Merck & Co., Inc. | Method for treating pediculosis capitisinfestation |
| US5972987A (en) * | 1999-03-16 | 1999-10-26 | Lori Fox Reid | Method for removing nits from hair |
| NL1011681C2 (nl) | 1999-03-26 | 2000-09-27 | Campina Melkunie Bv | Werkwijze en samenstelling voor het bestrijden van luizen. |
| US6277389B1 (en) | 1999-03-31 | 2001-08-21 | Erroll M. Pullen | Non-toxic aqueous pesticide |
| US6350724B1 (en) | 1999-04-20 | 2002-02-26 | Effcon Laboratories, Inc. | Lice removing composition |
| US6342253B1 (en) | 1999-05-18 | 2002-01-29 | Karen L. Whitledge | Use of essential oils to repel and treat head lice |
| US6115958A (en) | 1999-06-29 | 2000-09-12 | Enderle; A. Joy | Head lice treatment protocol |
| US6762158B2 (en) | 1999-07-01 | 2004-07-13 | Johnson & Johnson Consumer Companies, Inc. | Personal care compositions comprising liquid ester mixtures |
| HUP0202823A2 (en) * | 1999-08-12 | 2003-03-28 | Lilly Co Eli | Topical organic ectoparasiticidal formulations |
| WO2001012173A1 (en) | 1999-08-13 | 2001-02-22 | Effcon Laboratories, Inc. | Low concentration pest treatment composition and method |
| EP1207908A4 (en) | 1999-08-19 | 2002-09-11 | David Holzer | METHOD FOR TREATING INSECT INFECTION OF THE BODY |
| AUPQ246999A0 (en) | 1999-08-26 | 1999-09-16 | Australian Native Foods Management Ltd | Insecticidal composition |
| GB9921858D0 (en) | 1999-09-16 | 1999-11-17 | Ansell Jane | Composition and method for the eradication of head lice |
| ATE253825T1 (de) | 1999-09-16 | 2003-11-15 | Durminster Ltd | Verfahren und zusammensetzung zur arthropodenbekämpfung |
| AU1421901A (en) | 1999-10-21 | 2001-05-08 | Maria Teresa Delgadillo Guillen | Atoxic insecticide, bactericide, fungicide and antimicotic agent |
| AUPQ441699A0 (en) * | 1999-12-02 | 2000-01-06 | Eli Lilly And Company | Pour-on formulations |
| JP2001240541A (ja) * | 2000-03-02 | 2001-09-04 | Kanto Kachiku Rinsho Center:Kk | 動物外部寄生虫の駆除方法及び駆除剤 |
| AR035912A1 (es) * | 2000-03-02 | 2004-07-28 | Aventis Cropscience Sa | Compuestos de 4-tiometilpirazol, composicion plaguicida, metodo para el control de plagas en un lugar, semillas tratadas o recubiertas,uso de estos compuestos o composiciones para el control de plagas, uso de estos compuestos para preparar un medicamento veterinario, y,proceso para la preparacion de |
| WO2001078750A1 (en) | 2000-04-17 | 2001-10-25 | Care Technologies, Inc. | Lice remover composition |
| JP2002012595A (ja) * | 2000-04-27 | 2002-01-15 | Sankyo Co Ltd | ミルベマイシン誘導体 |
| AU2001274877A1 (en) | 2000-05-19 | 2001-12-03 | Effcon Laboratories, Inc. | Pest treatment composition |
| BG518Y1 (bg) | 2001-04-09 | 2002-04-30 | "ВИП Системс"ЕООД | Препарат за борба с pediculis humanis |
-
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147800A (en) * | 1977-01-17 | 1979-04-03 | Block Drug Company, Inc. | Pediculicidal toxicants |
| US6303581B2 (en) * | 1999-01-26 | 2001-10-16 | Dale L. Pearlman | Methods and kits for removing, treating, or preventing lice with driable pedicul ostatic agents |
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