AU2003215087B2 - Heteroaryl compounds useful as inhibitors of GSK-3 - Google Patents

Heteroaryl compounds useful as inhibitors of GSK-3 Download PDF

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Publication number
AU2003215087B2
AU2003215087B2 AU2003215087A AU2003215087A AU2003215087B2 AU 2003215087 B2 AU2003215087 B2 AU 2003215087B2 AU 2003215087 A AU2003215087 A AU 2003215087A AU 2003215087 A AU2003215087 A AU 2003215087A AU 2003215087 B2 AU2003215087 B2 AU 2003215087B2
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Australia
Prior art keywords
benzoimidazol
furazan
ring
nitrogen
disease
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Ceased
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AU2003215087A
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AU2003215087A1 (en
Inventor
Michael J Arnost
Jeremy Green
Scott L Harbeson
Vladimir Savic
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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AU2003215087A 2002-02-06 2003-02-06 Heteroaryl compounds useful as inhibitors of GSK-3 Ceased AU2003215087B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35484302P 2002-02-06 2002-02-06
US60/354,843 2002-02-06
PCT/US2003/003655 WO2003066629A2 (en) 2002-02-06 2003-02-06 Heteroaryl compounds useful as inhibitors of gsk-3

Publications (2)

Publication Number Publication Date
AU2003215087A1 AU2003215087A1 (en) 2003-09-02
AU2003215087B2 true AU2003215087B2 (en) 2009-07-16

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AU2003215087A Ceased AU2003215087B2 (en) 2002-02-06 2003-02-06 Heteroaryl compounds useful as inhibitors of GSK-3

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US (2) US20040034037A1 (https=)
EP (2) EP1472245A2 (https=)
JP (2) JP4656838B2 (https=)
KR (1) KR20040084896A (https=)
AU (1) AU2003215087B2 (https=)
CA (1) CA2475633C (https=)
ES (1) ES2437391T3 (https=)
MX (1) MXPA04007697A (https=)
NO (1) NO20043726L (https=)
PL (1) PL372198A1 (https=)
RU (1) RU2004126671A (https=)
SG (1) SG159380A1 (https=)
WO (1) WO2003066629A2 (https=)

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