AU2003210885B2 - Albumin-fused kunitz domain peptides - Google Patents
Albumin-fused kunitz domain peptides Download PDFInfo
- Publication number
- AU2003210885B2 AU2003210885B2 AU2003210885A AU2003210885A AU2003210885B2 AU 2003210885 B2 AU2003210885 B2 AU 2003210885B2 AU 2003210885 A AU2003210885 A AU 2003210885A AU 2003210885 A AU2003210885 A AU 2003210885A AU 2003210885 B2 AU2003210885 B2 AU 2003210885B2
- Authority
- AU
- Australia
- Prior art keywords
- albumin
- albumin fusion
- fusion protein
- fragment
- variant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A61K38/38—Albumins
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- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/475—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
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- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- C—CHEMISTRY; METALLURGY
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- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8114—Kunitz type inhibitors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/26—Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
- C12Y301/26003—Ribonuclease III (3.1.26.3)
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- C—CHEMISTRY; METALLURGY
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- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
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- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Immunology (AREA)
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- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009212820A AU2009212820B2 (en) | 2002-02-07 | 2009-08-27 | Albumin-fused kunitz domain peptides |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35554702P | 2002-02-07 | 2002-02-07 | |
| US60/355,547 | 2002-02-07 | ||
| PCT/US2003/003616 WO2003066824A2 (en) | 2002-02-07 | 2003-02-07 | Albumin-fused kunitz domain peptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2009212820A Division AU2009212820B2 (en) | 2002-02-07 | 2009-08-27 | Albumin-fused kunitz domain peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003210885A1 AU2003210885A1 (en) | 2003-09-02 |
| AU2003210885B2 true AU2003210885B2 (en) | 2009-06-04 |
Family
ID=27734531
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003210885A Ceased AU2003210885B2 (en) | 2002-02-07 | 2003-02-07 | Albumin-fused kunitz domain peptides |
| AU2003244515A Abandoned AU2003244515A1 (en) | 2002-02-07 | 2003-02-07 | Albumin-fused anti-angiogenesis peptides |
| AU2003244516A Abandoned AU2003244516A1 (en) | 2002-02-07 | 2003-02-07 | Hiv inhibiting proteins |
| AU2008264153A Abandoned AU2008264153A1 (en) | 2002-02-07 | 2008-12-23 | HIV inhibiting proteins |
| AU2009212820A Expired - Fee Related AU2009212820B2 (en) | 2002-02-07 | 2009-08-27 | Albumin-fused kunitz domain peptides |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003244515A Abandoned AU2003244515A1 (en) | 2002-02-07 | 2003-02-07 | Albumin-fused anti-angiogenesis peptides |
| AU2003244516A Abandoned AU2003244516A1 (en) | 2002-02-07 | 2003-02-07 | Hiv inhibiting proteins |
| AU2008264153A Abandoned AU2008264153A1 (en) | 2002-02-07 | 2008-12-23 | HIV inhibiting proteins |
| AU2009212820A Expired - Fee Related AU2009212820B2 (en) | 2002-02-07 | 2009-08-27 | Albumin-fused kunitz domain peptides |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20060122374A1 (enExample) |
| EP (4) | EP2090589A1 (enExample) |
| JP (4) | JP2005530484A (enExample) |
| KR (4) | KR20040095217A (enExample) |
| CN (3) | CN1642567A (enExample) |
| AU (5) | AU2003210885B2 (enExample) |
| CA (3) | CA2475539A1 (enExample) |
| NZ (3) | NZ534310A (enExample) |
| WO (3) | WO2003066824A2 (enExample) |
| ZA (3) | ZA200406124B (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2229236T3 (es) | 1994-01-11 | 2005-04-16 | Dyax Corporation | Inhibidores de la plasmina humana derivados de los dominios de kunitz. |
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| ATE528014T1 (de) | 2002-06-07 | 2011-10-15 | Dyax Corp | Polypeptid mit modifizierten kunitz domains |
| GB0217033D0 (en) * | 2002-07-23 | 2002-08-28 | Delta Biotechnology Ltd | Gene and polypeptide sequences |
| EP1542710B1 (en) * | 2002-08-28 | 2012-09-26 | Dyax Corp. | Methods for preserving organs and tissues |
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| WO2001047958A2 (en) * | 1999-12-29 | 2001-07-05 | Zymogenetics, Inc. | Kunitz domain polypeptide zkun10 |
| WO2001079443A2 (en) * | 2000-04-12 | 2001-10-25 | Human Genome Sciences, Inc. | Albumin fusion proteins |
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