KR20040095217A - 알부민-융합 항-혈관신생 펩타이드 - Google Patents

알부민-융합 항-혈관신생 펩타이드 Download PDF

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Publication number
KR20040095217A
KR20040095217A KR10-2004-7012255A KR20047012255A KR20040095217A KR 20040095217 A KR20040095217 A KR 20040095217A KR 20047012255 A KR20047012255 A KR 20047012255A KR 20040095217 A KR20040095217 A KR 20040095217A
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South Korea
Prior art keywords
albumin
fusion protein
albumin fusion
angiogenesis
leu
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KR10-2004-7012255A
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English (en)
Korean (ko)
Inventor
머틴스피터
셀릭일한
키스커올리버
슬립다렐
헤이조안나
하우저한스-피터
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델타 바이오테크놀로지 리미티드
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Publication of KR20040095217A publication Critical patent/KR20040095217A/ko
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    • A—HUMAN NECESSITIES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
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    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • C12Y—ENZYMES
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    • C12Y301/26—Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26003—Ribonuclease III (3.1.26.3)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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    • C12N2740/00—Reverse transcribing RNA viruses
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    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Bioinformatics & Cheminformatics (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
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  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
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  • Diabetes (AREA)
  • Hematology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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KR10-2004-7012255A 2002-02-07 2003-02-07 알부민-융합 항-혈관신생 펩타이드 Ceased KR20040095217A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35554702P 2002-02-07 2002-02-07
US60/355,547 2002-02-07
PCT/IB2003/000433 WO2003066085A1 (en) 2002-02-07 2003-02-07 Albumin-fused anti-angiogenesis peptides

Publications (1)

Publication Number Publication Date
KR20040095217A true KR20040095217A (ko) 2004-11-12

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Family Applications (4)

Application Number Title Priority Date Filing Date
KR10-2004-7012255A Ceased KR20040095217A (ko) 2002-02-07 2003-02-07 알부민-융합 항-혈관신생 펩타이드
KR10-2004-7012256A Ceased KR20050002823A (ko) 2002-02-07 2003-02-07 알부민-융합 쿠니츠 도메인 펩타이드
KR1020107028953A Ceased KR20110014661A (ko) 2002-02-07 2003-02-07 알부민-융합 쿠니츠 도메인 펩타이드
KR10-2004-7012254A Ceased KR20040089608A (ko) 2002-02-07 2003-02-07 Ｈｉｖ 억제 단백질

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KR10-2004-7012256A Ceased KR20050002823A (ko) 2002-02-07 2003-02-07 알부민-융합 쿠니츠 도메인 펩타이드
KR1020107028953A Ceased KR20110014661A (ko) 2002-02-07 2003-02-07 알부민-융합 쿠니츠 도메인 펩타이드
KR10-2004-7012254A Ceased KR20040089608A (ko) 2002-02-07 2003-02-07 Ｈｉｖ 억제 단백질

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Country Link
US (4) US20060122374A1 (enExample)
EP (4) EP2090589A1 (enExample)
JP (4) JP2005538932A (enExample)
KR (4) KR20040095217A (enExample)
CN (3) CN1646154B (enExample)
AU (5) AU2003210885B2 (enExample)
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