ATE512231T1 - Impfstoffe, immuntherapeutika und verfahren zur anwendung derselben - Google Patents
Impfstoffe, immuntherapeutika und verfahren zur anwendung derselbenInfo
- Publication number
- ATE512231T1 ATE512231T1 AT99936096T AT99936096T ATE512231T1 AT E512231 T1 ATE512231 T1 AT E512231T1 AT 99936096 T AT99936096 T AT 99936096T AT 99936096 T AT99936096 T AT 99936096T AT E512231 T1 ATE512231 T1 AT E512231T1
- Authority
- AT
- Austria
- Prior art keywords
- vaccines
- methods
- disclosed
- immunotherapeutics
- same
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5421—IL-8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7620798P | 1998-02-27 | 1998-02-27 | |
PCT/US1999/004332 WO1999043839A1 (en) | 1998-02-27 | 1999-02-26 | Vaccines, immunotherapeutics and methods for using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE512231T1 true ATE512231T1 (de) | 2011-06-15 |
Family
ID=22130587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99936096T ATE512231T1 (de) | 1998-02-27 | 1999-02-26 | Impfstoffe, immuntherapeutika und verfahren zur anwendung derselben |
Country Status (12)
Country | Link |
---|---|
US (2) | US8119395B1 (de) |
EP (1) | EP1078093B1 (de) |
JP (3) | JP2002504380A (de) |
KR (2) | KR100743894B1 (de) |
CN (1) | CN100352930C (de) |
AT (1) | ATE512231T1 (de) |
AU (1) | AU759603B2 (de) |
BR (1) | BR9908267A (de) |
CA (2) | CA2322160C (de) |
IL (3) | IL138075A0 (de) |
MX (1) | MXPA00008352A (de) |
WO (1) | WO1999043839A1 (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020136722A1 (en) * | 1997-06-18 | 2002-09-26 | Heath Andrew William | Vaccination method |
WO2001087066A1 (en) * | 2000-05-12 | 2001-11-22 | The Trustees Of The University Of Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
ATE512231T1 (de) | 1998-02-27 | 2011-06-15 | Univ Pennsylvania | Impfstoffe, immuntherapeutika und verfahren zur anwendung derselben |
SE9904863D0 (sv) * | 1999-12-30 | 1999-12-30 | Medscand Medical Ab | New use |
US7371392B2 (en) | 2000-02-02 | 2008-05-13 | The United States Of America As Represented By The Department Of Health And Human Services | Cd40 ligand adjuvant for respiratory syncytial virus |
US20020022017A1 (en) * | 2000-04-12 | 2002-02-21 | Hua Yu | Regulation of systemic immune responses utilizing soluble CD40 |
US7361329B2 (en) | 2000-04-21 | 2008-04-22 | Chemocentryx, Inc. | Compositions for inducing an immune response |
ES2256232T3 (es) * | 2000-04-21 | 2006-07-16 | Chemocentryx, Inc. | Metodos y composiciones para provocar una respuesta inmunitaria. |
WO2001080887A2 (en) * | 2000-04-21 | 2001-11-01 | Chemocentryx, Inc. | Methods and chemokin compositions for inducing an immune response |
AU5810201A (en) | 2000-05-10 | 2001-11-20 | Aventis Pasteur | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
WO2001085209A2 (en) * | 2000-05-10 | 2001-11-15 | Eli Lilly And Company | Treating t-cell mediated diseases by modulating dr6 activity |
US6544780B1 (en) * | 2000-06-02 | 2003-04-08 | Genphar, Inc. | Adenovirus vector with multiple expression cassettes |
US7754201B2 (en) | 2000-06-02 | 2010-07-13 | GenPhar, Inc | Method of vaccination through serotype rotation |
CA2412436C (en) | 2000-06-05 | 2013-05-21 | The Trustees Of Columbia University In The City Of New York | Identification and use of human bone marrow-derived endothelial progenitor cells to improve myocardial function after ischemic injury |
US7183376B2 (en) | 2000-06-23 | 2007-02-27 | Maxygen, Inc. | Variant B7 co-stimulatory molecules |
JP2004513878A (ja) | 2000-06-23 | 2004-05-13 | マキシジェン, インコーポレイテッド | 新規同時刺激分子 |
DE60134408D1 (de) | 2000-07-14 | 2008-07-24 | Univ Pennsylvania | Für akzessorische hiv proteine kodierende dna impfstoffe |
ATE381351T1 (de) * | 2000-07-27 | 2008-01-15 | Univ Pennsylvania | Anwendung des herpes simplex virus glykoproteins- d zur unterdrückung von immunantworten |
AUPR524101A0 (en) | 2001-05-25 | 2001-06-21 | Council Of The Queensland Institute Of Medical Research, The | Antigen targeting |
WO2003035106A1 (en) * | 2001-10-24 | 2003-05-01 | Chemocentryx | Methods and compositions for inducing an immune response by co-administering a chemokine with an antigen |
US6923958B2 (en) * | 2002-03-02 | 2005-08-02 | The Scripps Research Institute | DNA vaccines encoding CEA and a CD40 ligand and methods of use thereof |
US7786278B2 (en) | 2002-04-09 | 2010-08-31 | Sanofi Pasteur Limited | Modified CEA nucleic acid and expression vectors |
US20030199464A1 (en) | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
CN100542608C (zh) * | 2002-10-24 | 2009-09-23 | 株式会社Eci | 树突细胞前体的血中水平上升剂 |
AU2003285586A1 (en) * | 2002-12-03 | 2004-06-23 | Medical Research Council | Regulatory t-cells |
EP2353615B1 (de) * | 2003-08-20 | 2014-11-19 | University of Miami | Zusammensetzungen und Verfahren zur Behandlung von entzündlicher Lungenerkrankung |
CA2550583C (en) | 2003-10-08 | 2013-01-15 | Sanofi Pasteur, Inc. | Modified cea /b7 vector |
GB0325836D0 (en) * | 2003-11-05 | 2003-12-10 | Celltech R&D Ltd | Biological products |
AU2004299512B2 (en) | 2003-12-17 | 2010-11-25 | Janssen Alzheimer Immunotherapy | Abeta immunogenic peptide carrier conjugates and methods of producing same |
US20070134762A1 (en) | 2003-12-17 | 2007-06-14 | Arumugham Rasappa G | Immunogenic peptide carrier conjugates and methods of producing same |
GB0410220D0 (en) | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
TW200613554A (en) | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
US20060121031A1 (en) | 2004-12-07 | 2006-06-08 | Mckenzie Brent S | Relay vaccine |
US20070128184A1 (en) | 2005-08-30 | 2007-06-07 | Eckhard Podack | Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists and immunotoxins |
EP1979488A4 (de) * | 2006-01-09 | 2009-05-27 | Univ California | Immunstimulierende kombinationen aus tnfrsf, tlr, nlr, rhr, purinergischem rezeptor, und zytokin-rezeptor-antaonisten für impfstoffe und die tumorimmuntherapie |
US9259463B2 (en) | 2006-01-16 | 2016-02-16 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Chlamydia vaccine |
SI2495307T1 (en) | 2006-07-13 | 2018-05-31 | Wyeth Llc | Production of the calibration factor IX with an improved glycolization pattern |
JP5401319B2 (ja) | 2006-11-03 | 2014-01-29 | ワイス・エルエルシー | 細胞培養における解糖阻害物質 |
EP2924113B1 (de) | 2007-03-02 | 2019-04-10 | Wyeth LLC | Verwendung von kupfer und glutamat in zellkulturen zur herstellung von polypeptiden |
KR20110089185A (ko) | 2008-11-25 | 2011-08-04 | 바이오겐 아이덱 엠에이 인코포레이티드 | 신경계 세포의 생존을 촉진하기 위한 dr6 및 p75 길항제의 용도 |
KR20120089259A (ko) | 2009-08-03 | 2012-08-09 | 유니버시티 오브 마이애미 | T 조절 세포의 생체 내 확장 방법 |
JP5553906B2 (ja) | 2009-12-23 | 2014-07-23 | グラダリス インク. | フューリンノックダウン及びgm−csf増強(fang)癌ワクチン |
US9157084B2 (en) | 2009-12-23 | 2015-10-13 | Gradalis, Inc. | Furin-knockdown bi-functional RNA |
JP5388971B2 (ja) | 2010-08-24 | 2014-01-15 | 住友重機械工業株式会社 | 減速装置 |
CN103619350A (zh) * | 2011-03-11 | 2014-03-05 | 麦克马斯特大学 | 包含组蛋白去乙酰化酶抑制剂的疫苗接种方法 |
MX2015000789A (es) | 2012-07-19 | 2015-05-07 | Zoetis Llc | Composiciones de virus de la gripe bovina. |
WO2014018724A1 (en) | 2012-07-27 | 2014-01-30 | Zoetis Llc | Tick toxin compositions |
KR102565827B1 (ko) | 2013-01-09 | 2023-08-11 | 유니버시티 오브 마이애미 | TL1A-Ig 융합 단백질을 사용한 T 조절 세포의 조절을 위한 조성물 및 방법 |
AU2014234982A1 (en) | 2013-03-15 | 2015-09-24 | Zoetis Services Llc | Cross-protection of bovines against B. trehalosi infection by a multi-valent vaccine |
WO2015076282A1 (ja) * | 2013-11-20 | 2015-05-28 | 国立大学法人北海道大学 | 免疫制御剤 |
HRP20221440T1 (hr) | 2015-08-14 | 2023-02-03 | Zoetis Services Llc | Pripravci bakterije mycoplasma bovis |
WO2017123201A1 (en) | 2016-01-11 | 2017-07-20 | Zoetis Services Llc | Novel cross protective vaccine compositions for porcine epidemic diarrhea virus |
GB201703529D0 (en) | 2017-03-06 | 2017-04-19 | Cambridge Entpr Ltd | Vaccine composition |
RU2021117813A (ru) | 2017-12-13 | 2021-06-25 | Иновио Фармасьютикалз, Инк. | Мезотелин-нацеленные вакцины от рака и их применение |
CN110464841B (zh) * | 2019-08-19 | 2020-05-22 | 启辰生生物科技(珠海)有限公司 | 免疫增强的药物组合物及其应用 |
US11597770B2 (en) | 2020-01-24 | 2023-03-07 | Pfizer Inc. | Anti-E-selectin antibodies, compositions and methods of use |
CN113005072A (zh) * | 2021-04-09 | 2021-06-22 | 佛山科学技术学院 | 一种马链球菌兽疫亚种基因缺失株及其制备方法和应用 |
WO2023177655A1 (en) | 2022-03-14 | 2023-09-21 | Generation Bio Co. | Heterologous prime boost vaccine compositions and methods of use |
Family Cites Families (46)
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1999
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- 1999-02-26 JP JP2000533578A patent/JP2002504380A/ja active Pending
- 1999-02-26 CA CA 2322160 patent/CA2322160C/en not_active Expired - Fee Related
- 1999-02-26 CA CA 2792479 patent/CA2792479A1/en not_active Abandoned
- 1999-02-26 WO PCT/US1999/004332 patent/WO1999043839A1/en active Application Filing
- 1999-02-26 KR KR1020007009514A patent/KR100743894B1/ko not_active IP Right Cessation
- 1999-02-26 CN CNB998031828A patent/CN100352930C/zh not_active Expired - Fee Related
- 1999-02-26 BR BR9908267A patent/BR9908267A/pt not_active IP Right Cessation
- 1999-02-26 AU AU33130/99A patent/AU759603B2/en not_active Ceased
- 1999-02-26 IL IL13807599A patent/IL138075A0/xx unknown
- 1999-02-26 KR KR1020077005921A patent/KR20070039615A/ko active Search and Examination
- 1999-02-26 EP EP99936096A patent/EP1078093B1/de not_active Expired - Lifetime
- 1999-02-26 MX MXPA00008352A patent/MXPA00008352A/es not_active IP Right Cessation
- 1999-02-26 US US09/622,452 patent/US8119395B1/en not_active Expired - Fee Related
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- 2009-07-09 JP JP2009162877A patent/JP5485601B2/ja not_active Expired - Fee Related
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- 2010-02-23 JP JP2010037428A patent/JP2010187672A/ja active Pending
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2012
- 2012-01-27 US US13/360,389 patent/US20130045180A9/en not_active Abandoned
- 2012-06-03 IL IL220133A patent/IL220133A0/en unknown
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AU759603B2 (en) | 2003-04-17 |
IL220133A0 (en) | 2012-07-31 |
CA2322160A1 (en) | 1999-09-02 |
EP1078093A1 (de) | 2001-02-28 |
JP2010187672A (ja) | 2010-09-02 |
CA2322160C (en) | 2013-01-29 |
CN100352930C (zh) | 2007-12-05 |
US20130045180A9 (en) | 2013-02-21 |
US20120195852A1 (en) | 2012-08-02 |
EP1078093B1 (de) | 2011-06-08 |
KR20010082517A (ko) | 2001-08-30 |
KR20070039615A (ko) | 2007-04-12 |
IL138075A (en) | 2012-08-30 |
CN1291235A (zh) | 2001-04-11 |
WO1999043839A1 (en) | 1999-09-02 |
CA2792479A1 (en) | 1999-09-02 |
JP2009263396A (ja) | 2009-11-12 |
JP2002504380A (ja) | 2002-02-12 |
US8119395B1 (en) | 2012-02-21 |
IL138075A0 (en) | 2001-10-31 |
BR9908267A (pt) | 2000-10-24 |
JP5485601B2 (ja) | 2014-05-07 |
EP1078093A4 (de) | 2001-12-05 |
AU3313099A (en) | 1999-09-15 |
MXPA00008352A (es) | 2002-10-17 |
KR100743894B1 (ko) | 2007-07-30 |
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